Tom Van Maerken

Tom Van Maerken

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Tom Van Maerken

Tom Van Maerken

Publications by authors named "Tom Van Maerken"

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45Publications

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ALK positively regulates MYCN activity through repression of HBP1 expression.

Authors:
Shana Claeys Geertrui Denecker Kaat Durinck Bieke Decaesteker Liselot M Mus Siebe Loontiens Suzanne Vanhauwaert Kristina Althoff Caroline Wigerup Daniel Bexell Emmy Dolman Kai-Oliver Henrich Lea Wehrmann Ellen M Westerhout Jean-Baptiste Demoulin Candy Kumps Tom Van Maerken Genevieve Laureys Christophe Van Neste Bram De Wilde Olivier De Wever Frank Westermann Rogier Versteeg Jan J Molenaar Sven Påhlman Johannes H Schulte Katleen De Preter Frank Speleman

Oncogene 2019 04 11;38(15):2690-2705. Epub 2018 Dec 11.

Center for Medical Genetics Ghent (CMGG), Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1038/s41388-018-0595-3DOI Listing
April 2019

Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR.

Authors:
Steve Lefever Ali Rihani Joni Van der Meulen Filip Pattyn Tom Van Maerken Jo Van Dorpe Jan Hellemans Jo Vandesompele

Sci Rep 2019 Feb 15;9(1):2150. Epub 2019 Feb 15.

Center for Medical Genetics Ghent, Ghent University, Ghent, 9000, Belgium.

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http://dx.doi.org/10.1038/s41598-019-38581-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377641PMC
February 2019

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients.

Authors:
Fjoralba Zeka Anneleen Decock Alan Van Goethem Katrien Vanderheyden Fleur Demuynck Tim Lammens Hetty H Helsmoortel Joëlle Vermeulen Rosa Noguera Ana P Berbegall Valérie Combaret Gudrun Schleiermacher Geneviève Laureys Alexander Schramm Johannes H Schulte Sven Rahmann Julie Bienertová-Vašků Pavel Mazánek Marta Jeison Shifra Ash Michael D Hogarty Mirthala Moreno-Smith Eveline Barbieri Jason Shohet Frank Berthold Tom Van Maerken Frank Speleman Matthias Fischer Katleen De Preter Pieter Mestdagh Jo Vandesompele

JCI Insight 2018 12 6;3(23). Epub 2018 Dec 6.

Center for Medical Genetics, Department of Biomolecular Medicine, and.

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http://dx.doi.org/10.1172/jci.insight.97021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328024PMC
December 2018

MicroRNA Expression Analysis Using Small RNA Sequencing Discovery and RT-qPCR-Based Validation.

Authors:
Alan Van Goethem Pieter Mestdagh Tom Van Maerken Jo Vandesompele

Methods Mol Biol 2017 ;1654:197-208

Center for Medical Genetics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-7231-9_13DOI Listing
June 2018

Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium.

Authors:
Lien Cattoir Frederik Van Hoecke Tom Van Maerken Eveline Nys Inge Ryckaert Matthias De Boulle Anja Geerts Xavier Verhelst Isabelle Colle Veronik Hutse Vanessa Suin Magali Wautier Steven Van Gucht Hans Van Vlierberghe Elizaveta Padalko

J Clin Virol 2018 06 19;103:8-11. Epub 2018 Mar 19.

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium; School of Life Sciences, Hasselt University, Agoralaan Building D, 3590 Diepenbeek, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2018.03.004DOI Listing
June 2018

Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2 allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11.

Authors:
Annelot Baert Eva Machackova Ilse Coene Carol Cremin Kristin Turner Cheryl Portigal-Todd Marie Jill Asrat Jennifer Nuk Allison Mindlin Sean Young Andree MacMillan Tom Van Maerken Martin Trbusek Wendy McKinnon Marie E Wood William D Foulkes Marta Santamariña Miguel de la Hoya Lenka Foretova Bruce Poppe Anne Vral Toon Rosseel Kim De Leeneer Ana Vega Kathleen B M Claes

Hum Mutat 2018 04 22;39(4):515-526. Epub 2018 Jan 22.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://doi.wiley.com/10.1002/humu.23390
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http://dx.doi.org/10.1002/humu.23390DOI Listing
April 2018

Analytical and pre-analytical performance characteristics of a novel cartridge-type blood gas analyzer for point-of-care and laboratory testing.

Authors:
Matthijs Oyaert Tom Van Maerken Silke Bridts Silvi Van Loon Heleen Laverge Veronique Stove

Clin Biochem 2018 Mar 12;53:116-126. Epub 2018 Jan 12.

Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.clinbiochem.2018.01.007DOI Listing
March 2018

Meticulous plasma isolation is essential to avoid false low-level viraemia in Roche Cobas HIV-1 viral load assays.

Authors:
Virginie Mortier Leen Vancoillie Kenny Dauwe Delfien Staelens Els Demecheleer Marlies Schauvliege Sylvie Dinakis Tom Van Maerken Géraldine Dessilly Jean Ruelle Chris Verhofstede

Antivir Ther 2018 ;23(3):277-281

AIDS Reference Laboratory, Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.3851/IMP3203DOI Listing
January 2018

Hepatitis E virus serology and PCR: does the methodology matter?

Authors:
Lien Cattoir Frederik Van Hoecke Tom Van Maerken Eveline Nys Inge Ryckaert Matthias De Boulle Anja Geerts Xavier Verhelst Isabelle Colle Veronik Hutse Vanessa Suin Magali Wautier Steven Van Gucht Hans Van Vlierberghe Elizaveta Padalko

Arch Virol 2017 Sep 18;162(9):2625-2632. Epub 2017 May 18.

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, De Pintelaan 185, 2P8, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00705-017-3395-0DOI Listing
September 2017

Accelerating drug development for neuroblastoma - New Drug Development Strategy: an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma project.

Authors:
Lucas Moreno Hubert Caron Birgit Geoerger Angelika Eggert Gudrun Schleiermacher Penelope Brock Dominique Valteau-Couanet Louis Chesler Johannes H Schulte Katleen De Preter Jan Molenaar Alexander Schramm Martin Eilers Tom Van Maerken John Inge Johnsen Michelle Garrett Sally L George Deborah A Tweddle Per Kogner Frank Berthold Jan Koster Giuseppe Barone Elizabeth R Tucker Lynley Marshall Ralf Herold Jaroslav Sterba Koen Norga Gilles Vassal Andrew Dj Pearson

Expert Opin Drug Discov 2017 08 26;12(8):801-811. Epub 2017 Jun 26.

c Paediatric Drug Development, Children and Young People's Unit , Royal Marsden Hospital , London , UK.

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http://dx.doi.org/10.1080/17460441.2017.1340269DOI Listing
August 2017

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma.

Authors:
Alan Van Goethem Nurten Yigit Myrthala Moreno-Smith Sanjeev A Vasudevan Eveline Barbieri Frank Speleman Jason Shohet Jo Vandesompele Tom Van Maerken

Oncotarget 2017 Aug 4;8(34):57047-57057. Epub 2017 Jul 4.

Center for Medical Genetics Ghent (CMGG), Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.18632/oncotarget.18982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593624PMC
August 2017

A negative lactate dehydrogenase activity corrected after sample neuraminidase treatment.

Authors:
Matthijs Oyaert Tom Van Maerken Evelien Bauwens Veronique Stove Joris Delanghe

Clin Chim Acta 2017 May 12;468:209-210. Epub 2017 Mar 12.

Department of Laboratory Medicine, University Hospital Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2017.03.011DOI Listing
May 2017

Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay.

Authors:
Annelot Baert Julie Depuydt Tom Van Maerken Bruce Poppe Fransiska Malfait Tim Van Damme Sylvia De Nobele Gianpaolo Perletti Kim De Leeneer Kathleen B M Claes Anne Vral

Oncol Rep 2017 Mar 25;37(3):1379-1386. Epub 2017 Jan 25.

Department of Basic Medical Sciences, Ghent University, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.3892/or.2017.5407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364849PMC
March 2017

Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis.

Authors:
Heidi V N Küsters-Vandevelde Vibeke Kruse Tom Van Maerken Tom Boterberg Rolph Pfundt David Creytens Caroline Van den Broecke Trudi C Machielsen Christian Koelsche Andreas von Deimling Benno Küsters Patricia J T A Groenen Pieter Wesseling Willeke A M Blokx

Exp Mol Pathol 2017 Feb 11;102(1):25-31. Epub 2016 Dec 11.

Department of Pathology, Radboud University Medical Center, P.O. Box 9100, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2016.12.006DOI Listing
February 2017

Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples.

Authors:
Alan Van Goethem Nurten Yigit Celine Everaert Myrthala Moreno-Smith Liselot M Mus Eveline Barbieri Frank Speleman Pieter Mestdagh Jason Shohet Tom Van Maerken Jo Vandesompele

Sci Rep 2016 11 30;6:37876. Epub 2016 Nov 30.

Center for Medical Genetics Ghent (CMGG), Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1038/srep37876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129013PMC
November 2016

An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers.

Authors:
Dana Madorsky-Feldman Miri Sklair-Levy Tamar Perri Yael Laitman Shani Paluch-Shimon Rita Schmutzler Kerstin Rhiem Jenny Lester Beth Y Karlan Christian F Singer Tom Van Maerken Kathleen Claes Joan Brunet Angel Izquierdo Alex Teulé Jong Won Lee Sung-Won Kim Banu Arun Anna Jakubowska Jan Lubinski Katherine Tucker Nicola K Poplawski Liliana Varesco Luigina Ada Bonelli Saundra S Buys Gillian Mitchell Marc Tischkowitz Anne-Marie Gerdes Caroline Seynaeve Mark Robson Ava Kwong Nadine Tung Nalven Tessa Susan M Domchek Andrew K Godwin Johanna Rantala Brita Arver Eitan Friedman

Breast Cancer Res Treat 2016 06 27;157(2):319-327. Epub 2016 Apr 27.

The High Risk Clinic, Meirav Center, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1007/s10549-016-3805-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508745PMC
June 2016

Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation.

Authors:
Annelot Baert Julie Depuydt Tom Van Maerken Bruce Poppe Fransiska Malfait Katrien Storm Jenneke van den Ende Tim Van Damme Sylvia De Nobele Gianpaolo Perletti Kim De Leeneer Kathleen B M Claes Anne Vral

Breast Cancer Res 2016 05 17;18(1):52. Epub 2016 May 17.

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://link.springer.com/content/pdf/10.1186%2Fs13058-016-07
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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s13058-016-0709-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869288PMC
May 2016

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.

Authors:
Huong D Meeks Honglin Song Kyriaki Michailidou Manjeet K Bolla Joe Dennis Qin Wang Daniel Barrowdale Debra Frost Lesley McGuffog Steve Ellis Bingjian Feng Saundra S Buys John L Hopper Melissa C Southey Andrea Tesoriero Paul A James Fiona Bruinsma Ian G Campbell Annegien Broeks Marjanka K Schmidt Frans B L Hogervorst Matthias W Beckman Peter A Fasching Olivia Fletcher Nichola Johnson Elinor J Sawyer Elio Riboli Susana Banerjee Usha Menon Ian Tomlinson Barbara Burwinkel Ute Hamann Frederik Marme Anja Rudolph Ramunas Janavicius Laima Tihomirova Nadine Tung Judy Garber Daniel Cramer Kathryn L Terry Elizabeth M Poole Shelley S Tworoger Cecilia M Dorfling Elizabeth J van Rensburg Andrew K Godwin Pascal Guénel Thérèse Truong Dominique Stoppa-Lyonnet Francesca Damiola Sylvie Mazoyer Olga M Sinilnikova Claudine Isaacs Christine Maugard Stig E Bojesen Henrik Flyger Anne-Marie Gerdes Thomas V O Hansen Allen Jensen Susanne K Kjaer Claus Hogdall Estrid Hogdall Inge Sokilde Pedersen Mads Thomassen Javier Benitez Anna González-Neira Ana Osorio Miguel de la Hoya Pedro Perez Segura Orland Diez Conxi Lazaro Joan Brunet Hoda Anton-Culver Lee Eunjung Esther M John Susan L Neuhausen Yuan Chun Ding Danielle Castillo Jeffrey N Weitzel Patricia A Ganz Robert L Nussbaum Salina B Chan Beth Y Karlan Jenny Lester Anna Wu Simon Gayther Susan J Ramus Weiva Sieh Alice S Whittermore Alvaro N A Monteiro Catherine M Phelan Mary Beth Terry Marion Piedmonte Kenneth Offit Mark Robson Douglas Levine Kirsten B Moysich Rikki Cannioto Sara H Olson Mary B Daly Katherine L Nathanson Susan M Domchek Karen H Lu Dong Liang Michelle A T Hildebrant Roberta Ness Francesmary Modugno Leigh Pearce Marc T Goodman Pamela J Thompson Hermann Brenner Katja Butterbach Alfons Meindl Eric Hahnen Barbara Wappenschmidt Hiltrud Brauch Thomas Brüning Carl Blomqvist Sofia Khan Heli Nevanlinna Liisa M Pelttari Kristiina Aittomäki Ralf Butzow Natalia V Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Johanna Rantala Veli-Matti Kosma Arto Mannermaa Diether Lambrechts Patrick Neven Kathleen B M Claes Tom Van Maerken Jenny Chang-Claude Dieter Flesch-Janys Florian Heitz Raymonda Varon-Mateeva Paolo Peterlongo Paolo Radice Alessandra Viel Monica Barile Bernard Peissel Siranoush Manoukian Marco Montagna Cristina Oliani Ana Peixoto Manuel R Teixeira Anita Collavoli Emily Hallberg Janet E Olson Ellen L Goode Steven N Hart Hermela Shimelis Julie M Cunningham Graham G Giles Roger L Milne Sue Healey Kathy Tucker Christopher A Haiman Brian E Henderson Mark S Goldberg Marc Tischkowitz Jacques Simard Penny Soucy Diana M Eccles Nhu Le Anne-Lise Borresen-Dale Vessela Kristensen Helga B Salvesen Line Bjorge Elisa V Bandera Harvey Risch Wei Zheng Alicia Beeghly-Fadiel Hui Cai Katri Pylkäs Robert A E M Tollenaar Ans M W van der Ouweland Irene L Andrulis Julia A Knight Steven Narod Peter Devilee Robert Winqvist Jonine Figueroa Mark H Greene Phuong L Mai Jennifer T Loud Montserrat García-Closas Minouk J Schoemaker Kamila Czene Hatef Darabi Iain McNeish Nadeem Siddiquil Rosalind Glasspool Ava Kwong Sue K Park Soo Hwang Teo Sook-Yee Yoon Keitaro Matsuo Satoyo Hosono Yin Ling Woo Yu-Tang Gao Lenka Foretova Christian F Singer Christine Rappaport-Feurhauser Eitan Friedman Yael Laitman Gad Rennert Evgeny N Imyanitov Peter J Hulick Olufunmilayo I Olopade Leigha Senter Edith Olah Jennifer A Doherty Joellen Schildkraut Linetta B Koppert Lambertus A Kiemeney Leon F A G Massuger Linda S Cook Tanja Pejovic Jingmei Li Ake Borg Anna Öfverholm Mary Anne Rossing Nicolas Wentzensen Karin Henriksson Angela Cox Simon S Cross Barbara J Pasini Mitul Shah Maria Kabisch Diana Torres Anna Jakubowska Jan Lubinski Jacek Gronwald Bjarni A Agnarsson Jolanta Kupryjanczyk Joanna Moes-Sosnowska Florentia Fostira Irene Konstantopoulou Susan Slager Michael Jones Antonis C Antoniou Andrew Berchuck Anthony Swerdlow Georgia Chenevix-Trench Alison M Dunning Paul D P Pharoah Per Hall Douglas F Easton Fergus J Couch Amanda B Spurdle David E Goldgar

J Natl Cancer Inst 2016 Feb 19;108(2). Epub 2015 Nov 19.

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http://jnci.oxfordjournals.org/content/108/2/djv315.full.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv31
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http://dx.doi.org/10.1093/jnci/djv315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907358PMC
February 2016

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

Authors:
Valentina Silvestri Daniel Barrowdale Anna Marie Mulligan Susan L Neuhausen Stephen Fox Beth Y Karlan Gillian Mitchell Paul James Darcy L Thull Kristin K Zorn Natalie J Carter Katherine L Nathanson Susan M Domchek Timothy R Rebbeck Susan J Ramus Robert L Nussbaum Olufunmilayo I Olopade Johanna Rantala Sook-Yee Yoon Maria A Caligo Laura Spugnesi Anders Bojesen Inge Sokilde Pedersen Mads Thomassen Uffe Birk Jensen Amanda Ewart Toland Leigha Senter Irene L Andrulis Gord Glendon Peter J Hulick Evgeny N Imyanitov Mark H Greene Phuong L Mai Christian F Singer Christine Rappaport-Fuerhauser Gero Kramer Joseph Vijai Kenneth Offit Mark Robson Anne Lincoln Lauren Jacobs Eva Machackova Lenka Foretova Marie Navratilova Petra Vasickova Fergus J Couch Emily Hallberg Kathryn J Ruddy Priyanka Sharma Sung-Won Kim Manuel R Teixeira Pedro Pinto Marco Montagna Laura Matricardi Adalgeir Arason Oskar Th Johannsson Rosa B Barkardottir Anna Jakubowska Jan Lubinski Angel Izquierdo Miguel Angel Pujana Judith Balmaña Orland Diez Gabriella Ivady Janos Papp Edith Olah Ava Kwong Heli Nevanlinna Kristiina Aittomäki Pedro Perez Segura Trinidad Caldes Tom Van Maerken Bruce Poppe Kathleen B M Claes Claudine Isaacs Camille Elan Christine Lasset Dominique Stoppa-Lyonnet Laure Barjhoux Muriel Belotti Alfons Meindl Andrea Gehrig Christian Sutter Christoph Engel Dieter Niederacher Doris Steinemann Eric Hahnen Karin Kast Norbert Arnold Raymonda Varon-Mateeva Dorothea Wand Andrew K Godwin D Gareth Evans Debra Frost Jo Perkins Julian Adlard Louise Izatt Radka Platte Ros Eeles Steve Ellis Ute Hamann Judy Garber Florentia Fostira George Fountzilas Barbara Pasini Giuseppe Giannini Piera Rizzolo Antonio Russo Laura Cortesi Laura Papi Liliana Varesco Domenico Palli Ines Zanna Antonella Savarese Paolo Radice Siranoush Manoukian Bernard Peissel Monica Barile Bernardo Bonanni Alessandra Viel Valeria Pensotti Stefania Tommasi Paolo Peterlongo Jeffrey N Weitzel Ana Osorio Javier Benitez Lesley McGuffog Sue Healey Anne-Marie Gerdes Bent Ejlertsen Thomas V O Hansen Linda Steele Yuan Chun Ding Nadine Tung Ramunas Janavicius David E Goldgar Saundra S Buys Mary B Daly Anita Bane Mary Beth Terry Esther M John Melissa Southey Douglas F Easton Georgia Chenevix-Trench Antonis C Antoniou Laura Ottini

Breast Cancer Res 2016 Feb 9;18(1):15. Epub 2016 Feb 9.

Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy.

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http://dx.doi.org/10.1186/s13058-016-0671-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746828PMC
February 2016

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.

Authors:
Ignacio Blanco Karoline Kuchenbaecker Daniel Cuadras Xianshu Wang Daniel Barrowdale Gorka Ruiz de Garibay Pablo Librado Alejandro Sánchez-Gracia Julio Rozas Núria Bonifaci Lesley McGuffog Vernon S Pankratz Abul Islam Francesca Mateo Antoni Berenguer Anna Petit Isabel Català Joan Brunet Lidia Feliubadaló Eva Tornero Javier Benítez Ana Osorio Teresa Ramón y Cajal Heli Nevanlinna Kristiina Aittomäki Banu K Arun Amanda E Toland Beth Y Karlan Christine Walsh Jenny Lester Mark H Greene Phuong L Mai Robert L Nussbaum Irene L Andrulis Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Rosa B Barkardottir Anna Jakubowska Jan Lubinski Katarzyna Durda Katarzyna Jaworska-Bieniek Kathleen Claes Tom Van Maerken Orland Díez Thomas V Hansen Lars Jønson Anne-Marie Gerdes Bent Ejlertsen Miguel de la Hoya Trinidad Caldés Alison M Dunning Clare Oliver Elena Fineberg Margaret Cook Susan Peock Emma McCann Alex Murray Chris Jacobs Gabriella Pichert Fiona Lalloo Carol Chu Huw Dorkins Joan Paterson Kai-Ren Ong Manuel R Teixeira Frans B L Hogervorst Annemarie H van der Hout Caroline Seynaeve Rob B van der Luijt Marjolijn J L Ligtenberg Peter Devilee Juul T Wijnen Matti A Rookus Hanne E J Meijers-Heijboer Marinus J Blok Ans M W van den Ouweland Cora M Aalfs Gustavo C Rodriguez Kelly-Anne A Phillips Marion Piedmonte Stacy R Nerenstone Victoria L Bae-Jump David M O'Malley Elena S Ratner Rita K Schmutzler Barbara Wappenschmidt Kerstin Rhiem Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Hansjoerg J Plendl Dieter Niederacher Christian Sutter Shan Wang-Gohrke Doris Steinemann Sabine Preisler-Adams Karin Kast Raymonda Varon-Mateeva Andrea Gehrig Anders Bojesen Inge Sokilde Pedersen Lone Sunde Uffe Birk Jensen Mads Thomassen Torben A Kruse Lenka Foretova Paolo Peterlongo Loris Bernard Bernard Peissel Giulietta Scuvera Siranoush Manoukian Paolo Radice Laura Ottini Marco Montagna Simona Agata Christine Maugard Jacques Simard Penny Soucy Andreas Berger Anneliese Fink-Retter Christian F Singer Christine Rappaport Daphne Geschwantler-Kaulich Muy-Kheng Tea Georg Pfeiler Esther M John Alex Miron Susan L Neuhausen Mary Beth Terry Wendy K Chung Mary B Daly David E Goldgar Ramunas Janavicius Cecilia M Dorfling Elisabeth J van Rensburg Florentia Fostira Irene Konstantopoulou Judy Garber Andrew K Godwin Edith Olah Steven A Narod Gad Rennert Shani Shimon Paluch Yael Laitman Eitan Friedman Annelie Liljegren Johanna Rantala Marie Stenmark-Askmalm Niklas Loman Evgeny N Imyanitov Ute Hamann Amanda B Spurdle Sue Healey Jeffrey N Weitzel Josef Herzog David Margileth Chiara Gorrini Manel Esteller Antonio Gómez Sergi Sayols Enrique Vidal Holger Heyn Dominique Stoppa-Lyonnet Melanie Léoné Laure Barjhoux Marion Fassy-Colcombet Antoine de Pauw Christine Lasset Sandra Fert Ferrer Laurent Castera Pascaline Berthet François Cornelis Yves-Jean Bignon Francesca Damiola Sylvie Mazoyer Olga M Sinilnikova Christopher A Maxwell Joseph Vijai Mark Robson Noah Kauff Marina J Corines Danylko Villano Julie Cunningham Adam Lee Noralane Lindor Conxi Lázaro Douglas F Easton Kenneth Offit Georgia Chenevix-Trench Fergus J Couch Antonis C Antoniou Miguel Angel Pujana

PLoS One 2015 1;10(4):e0120020. Epub 2015 Apr 1.

Breast Cancer and Systems Biology Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120020PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382299PMC
December 2015

CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients.

Authors:
Ali Rihani Bram De Wilde Fjoralba Zeka Geneviève Laureys Nadine Francotte Gian Paolo Tonini Simona Coco Rogier Versteeg Rosa Noguera Johannes H Schulte Angelika Eggert Raymond L Stallings Frank Speleman Jo Vandesompele Tom Van Maerken

PLoS One 2014 11;9(12):e114696. Epub 2014 Dec 11.

Center for Medical Genetics, Ghent University, Ghent, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114696PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263607PMC
October 2015

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment.

Authors:
Irina Lambertz Candy Kumps Shana Claeys Sven Lindner Anneleen Beckers Els Janssens Daniel R Carter Alex Cazes Belamy B Cheung Marilena De Mariano An De Bondt Sara De Brouwer Olivier Delattre Jay Gibbons Isabelle Janoueix-Lerosey Geneviève Laureys Chris Liang Glenn M Marchall Michael Porcu Junko Takita David Camacho Trujillo Ilse Van Den Wyngaert Nadine Van Roy Alan Van Goethem Tom Van Maerken Piotr Zabrocki Jan Cools Johannes H Schulte Jorge Vialard Frank Speleman Katleen De Preter

Clin Cancer Res 2015 Jul 24;21(14):3327-39. Epub 2015 Mar 24.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://clincancerres.aacrjournals.org/content/early/2015/03/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-2024DOI Listing
July 2015

Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma.

Authors:
Ali Rihani Jo Vandesompele Frank Speleman Tom Van Maerken

Cancer Cell Int 2015 30;15:76. Epub 2015 Jul 30.

Center for Medical Genetics, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1186/s12935-015-0224-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518532PMC
July 2015

Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors.

Authors:
Melanie Schwermer Sangkyun Lee Johannes Köster Tom van Maerken Harald Stephan Angelika Eggert Katharina Morik Johannes H Schulte Alexander Schramm

Oncotarget 2015 Jun;6(17):15425-35

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558161PMC
http://dx.doi.org/10.18632/oncotarget.3908DOI Listing
June 2015

Identification of miRNAs contributing to neuroblastoma chemoresistance.

Authors:
Duncan Ayers Pieter Mestdagh Tom Van Maerken Jo Vandesompele

Comput Struct Biotechnol J 2015 29;13:307-19. Epub 2015 Apr 29.

Center for Medical Genetics Ghent, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.csbj.2015.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427660PMC
May 2015

Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma.

Authors:
Ali Rihani Alan Van Goethem Maté Ongenaert Sara De Brouwer Pieter-Jan Volders Saurabh Agarwal Katleen De Preter Pieter Mestdagh Jason Shohet Frank Speleman Jo Vandesompele Tom Van Maerken

Sci Rep 2015 Mar 12;5:9027. Epub 2015 Mar 12.

Center for Medical Genetics, Ghent University, De Pintelaan 185, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1038/srep09027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356961PMC
March 2015

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.

Authors:
Paolo Peterlongo Jenny Chang-Claude Kirsten B Moysich Anja Rudolph Rita K Schmutzler Jacques Simard Penny Soucy Rosalind A Eeles Douglas F Easton Ute Hamann Stefan Wilkening Bowang Chen Matti A Rookus Marjanka K Schmidt Frederieke H van der Baan Amanda B Spurdle Logan C Walker Felicity Lose Ana-Teresa Maia Marco Montagna Laura Matricardi Jan Lubinski Anna Jakubowska Encarna B Gómez Garcia Olufunmilayo I Olopade Robert L Nussbaum Katherine L Nathanson Susan M Domchek Timothy R Rebbeck Banu K Arun Beth Y Karlan Sandra Orsulic Jenny Lester Wendy K Chung Alex Miron Melissa C Southey David E Goldgar Saundra S Buys Ramunas Janavicius Cecilia M Dorfling Elizabeth J van Rensburg Yuan Chun Ding Susan L Neuhausen Thomas V O Hansen Anne-Marie Gerdes Bent Ejlertsen Lars Jønson Ana Osorio Cristina Martínez-Bouzas Javier Benitez Edye E Conway Kathleen R Blazer Jeffrey N Weitzel Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Giulietta Scuvera Monica Barile Filomena Ficarazzi Frederique Mariette Stefano Fortuzzi Alessandra Viel Giuseppe Giannini Laura Papi Aline Martayan Maria Grazia Tibiletti Paolo Radice Athanassios Vratimos Florentia Fostira Judy E Garber Alan Donaldson Carole Brewer Claire Foo D Gareth R Evans Debra Frost Diana Eccles Angela Brady Jackie Cook Marc Tischkowitz Julian Adlard Julian Barwell Lisa Walker Louise Izatt Lucy E Side M John Kennedy Mark T Rogers Mary E Porteous Patrick J Morrison Radka Platte Rosemarie Davidson Shirley V Hodgson Steve Ellis Trevor Cole Andrew K Godwin Kathleen Claes Tom Van Maerken Alfons Meindl Andrea Gehrig Christian Sutter Christoph Engel Dieter Niederacher Doris Steinemann Hansjoerg Plendl Karin Kast Kerstin Rhiem Nina Ditsch Norbert Arnold Raymonda Varon-Mateeva Barbara Wappenschmidt Shan Wang-Gohrke Brigitte Bressac-de Paillerets Bruno Buecher Capucine Delnatte Claude Houdayer Dominique Stoppa-Lyonnet Francesca Damiola Isabelle Coupier Laure Barjhoux Laurence Venat-Bouvet Lisa Golmard Nadia Boutry-Kryza Olga M Sinilnikova Olivier Caron Pascal Pujol Sylvie Mazoyer Muriel Belotti Marion Piedmonte Michael L Friedlander Gustavo C Rodriguez Larry J Copeland Miguel de la Hoya Pedro Perez Segura Heli Nevanlinna Kristiina Aittomäki Theo A M van Os Hanne E J Meijers-Heijboer Annemarie H van der Hout Maaike P G Vreeswijk Nicoline Hoogerbrugge Margreet G E M Ausems Helena C van Doorn J Margriet Collée Edith Olah Orland Diez Ignacio Blanco Conxi Lazaro Joan Brunet Lidia Feliubadalo Cezary Cybulski Jacek Gronwald Katarzyna Durda Katarzyna Jaworska-Bieniek Grzegorz Sukiennicki Adalgeir Arason Jocelyne Chiquette Manuel R Teixeira Curtis Olswold Fergus J Couch Noralane M Lindor Xianshu Wang Csilla I Szabo Kenneth Offit Marina Corines Lauren Jacobs Mark E Robson Liying Zhang Vijai Joseph Andreas Berger Christian F Singer Christine Rappaport Daphne Geschwantler Kaulich Georg Pfeiler Muy-Kheng M Tea Catherine M Phelan Mark H Greene Phuong L Mai Gad Rennert Anna Marie Mulligan Gord Glendon Sandrine Tchatchou Irene L Andrulis Amanda Ewart Toland Anders Bojesen Inge Sokilde Pedersen Mads Thomassen Uffe Birk Jensen Yael Laitman Johanna Rantala Anna von Wachenfeldt Hans Ehrencrona Marie Stenmark Askmalm Åke Borg Karoline B Kuchenbaecker Lesley McGuffog Daniel Barrowdale Sue Healey Andrew Lee Paul D P Pharoah Georgia Chenevix-Trench Antonis C Antoniou Eitan Friedman

Cancer Epidemiol Biomarkers Prev 2015 Jan 21;24(1):308-16. Epub 2014 Oct 21.

Sheba Medical Center, Tel Aviv, Israel.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294951PMC
January 2015

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers.

Authors:
Karoline B Kuchenbaecker Susan L Neuhausen Mark Robson Daniel Barrowdale Lesley McGuffog Anna Marie Mulligan Irene L Andrulis Amanda B Spurdle Marjanka K Schmidt Rita K Schmutzler Christoph Engel Barbara Wappenschmidt Heli Nevanlinna Mads Thomassen Melissa Southey Paolo Radice Susan J Ramus Susan M Domchek Katherine L Nathanson Andrew Lee Sue Healey Robert L Nussbaum Timothy R Rebbeck Banu K Arun Paul James Beth Y Karlan Jenny Lester Ilana Cass Mary Beth Terry Mary B Daly David E Goldgar Saundra S Buys Ramunas Janavicius Laima Tihomirova Nadine Tung Cecilia M Dorfling Elizabeth J van Rensburg Linda Steele Thomas v O Hansen Bent Ejlertsen Anne-Marie Gerdes Finn C Nielsen Joe Dennis Julie Cunningham Steven Hart Susan Slager Ana Osorio Javier Benitez Mercedes Duran Jeffrey N Weitzel Isaac Tafur Mary Hander Paolo Peterlongo Siranoush Manoukian Bernard Peissel Gaia Roversi Giulietta Scuvera Bernardo Bonanni Paolo Mariani Sara Volorio Riccardo Dolcetti Liliana Varesco Laura Papi Maria Grazia Tibiletti Giuseppe Giannini Florentia Fostira Irene Konstantopoulou Judy Garber Ute Hamann Alan Donaldson Carole Brewer Claire Foo D Gareth Evans Debra Frost Diana Eccles Fiona Douglas Angela Brady Jackie Cook Marc Tischkowitz Julian Adlard Julian Barwell Kai-ren Ong Lisa Walker Louise Izatt Lucy E Side M John Kennedy Mark T Rogers Mary E Porteous Patrick J Morrison Radka Platte Ros Eeles Rosemarie Davidson Shirley Hodgson Steve Ellis Andrew K Godwin Kerstin Rhiem Alfons Meindl Nina Ditsch Norbert Arnold Hansjoerg Plendl Dieter Niederacher Christian Sutter Doris Steinemann Nadja Bogdanova-Markov Karin Kast Raymonda Varon-Mateeva Shan Wang-Gohrke Andrea Gehrig Birgid Markiefka Bruno Buecher Cédrick Lefol Dominique Stoppa-Lyonnet Etienne Rouleau Fabienne Prieur Francesca Damiola Laure Barjhoux Laurence Faivre Michel Longy Nicolas Sevenet Olga M Sinilnikova Sylvie Mazoyer Valérie Bonadona Virginie Caux-Moncoutier Claudine Isaacs Tom Van Maerken Kathleen Claes Marion Piedmonte Lesley Andrews John Hays Gustavo C Rodriguez Trinidad Caldes Miguel de la Hoya Sofia Khan Frans B L Hogervorst Cora M Aalfs J L de Lange Hanne E J Meijers-Heijboer Annemarie H van der Hout Juul T Wijnen K E P van Roozendaal Arjen R Mensenkamp Ans M W van den Ouweland Carolien H M van Deurzen Rob B van der Luijt Edith Olah Orland Diez Conxi Lazaro Ignacio Blanco Alex Teulé Mireia Menendez Anna Jakubowska Jan Lubinski Cezary Cybulski Jacek Gronwald Katarzyna Jaworska-Bieniek Katarzyna Durda Adalgeir Arason Christine Maugard Penny Soucy Marco Montagna Simona Agata Manuel R Teixeira Curtis Olswold Noralane Lindor Vernon S Pankratz Emily Hallberg Xianshu Wang Csilla I Szabo Joseph Vijai Lauren Jacobs Marina Corines Anne Lincoln Andreas Berger Anneliese Fink-Retter Christian F Singer Christine Rappaport Daphne Gschwantler Kaulich Georg Pfeiler Muy-Kheng Tea Catherine M Phelan Phuong L Mai Mark H Greene Gad Rennert Evgeny N Imyanitov Gord Glendon Amanda Ewart Toland Anders Bojesen Inge Sokilde Pedersen Uffe Birk Jensen Maria A Caligo Eitan Friedman Raanan Berger Yael Laitman Johanna Rantala Brita Arver Niklas Loman Ake Borg Hans Ehrencrona Olufunmilayo I Olopade Jacques Simard Douglas F Easton Georgia Chenevix-Trench Kenneth Offit Fergus J Couch Antonis C Antoniou

Breast Cancer Res 2014 Dec 31;16(6):3416. Epub 2014 Dec 31.

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http://dx.doi.org/10.1186/s13058-014-0492-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406179PMC
December 2014

Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastoma.

Authors:
Ali Rihani Tom Van Maerken Bram De Wilde Fjoralba Zeka Geneviève Laureys Koen Norga Gian Paolo Tonini Simona Coco Rogier Versteeg Rosa Noguera Johannes H Schulte Angelika Eggert Raymond L Stallings Frank Speleman Jo Vandesompele

Pediatr Blood Cancer 2014 Oct 4;61(10):1867-70. Epub 2014 Jan 4.

Center for Medical Genetics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/pbc.24927DOI Listing
October 2014

Effective Alu repeat based RT-Qpcr normalization in cancer cell perturbation experiments.

Authors:
Ali Rihani Tom Van Maerken Filip Pattyn Gert Van Peer Anneleen Beckers Sara De Brouwer Candy Kumps Evelien Mets Joni Van der Meulen Pieter Rondou Carina Leonelli Pieter Mestdagh Frank Speleman Jo Vandesompele

PLoS One 2013 14;8(8):e71776. Epub 2013 Aug 14.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743747PMC
April 2014

Pharmacologic activation of wild-type p53 by nutlin therapy in childhood cancer.

Authors:
Tom Van Maerken Ali Rihani Alan Van Goethem Anne De Paepe Frank Speleman Jo Vandesompele

Cancer Lett 2014 Mar 18;344(2):157-65. Epub 2013 Nov 18.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.canlet.2013.11.002DOI Listing
March 2014

MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance.

Authors:
Giuseppe Barone Deborah A Tweddle Jason M Shohet Louis Chesler Lucas Moreno Andrew D J Pearson Tom Van Maerken

Curr Drug Targets 2014 Jan;15(1):114-23

The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, United Kingdom.

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January 2014

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes.

Authors:
Candy Kumps Annelies Fieuw Pieter Mestdagh Björn Menten Steve Lefever Filip Pattyn Sara De Brouwer Tom Sante Johannes Hubertus Schulte Alexander Schramm Nadine Van Roy Tom Van Maerken Rosa Noguera Valérie Combaret Christine Devalck Frank Westermann Geneviève Laureys Angelika Eggert Jo Vandesompele Katleen De Preter Frank Speleman

PLoS One 2013 4;8(1):e52321. Epub 2013 Jan 4.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052321PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537730PMC
July 2013

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.

Authors:
Anneleen Decock Maté Ongenaert Jasmien Hoebeeck Katleen De Preter Gert Van Peer Wim Van Criekinge Ruth Ladenstein Johannes H Schulte Rosa Noguera Raymond L Stallings An Van Damme Geneviève Laureys Joëlle Vermeulen Tom Van Maerken Frank Speleman Jo Vandesompele

Genome Biol 2012 Oct 3;13(10):R95. Epub 2012 Oct 3.

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http://dx.doi.org/10.1186/gb-2012-13-10-r95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491423PMC
October 2012

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells.

Authors:
An De Weer Joni Van der Meulen Pieter Rondou Tom Taghon Torsten A Konrad Katleen De Preter Pieter Mestdagh Tom Van Maerken Nadine Van Roy Marta Jeison Isaac Yaniv Barbara Cauwelier Lucien Noens Hélène-Antoine Poirel Peter Vandenberghe Frédéric Lambert Anne De Paepe Maria García Sánchez Maria Odero Bruno Verhasselt Jan Philippé Joke Vandesompele Rotraud Wieser Nicole Dastugue Pieter Van Vlierberghe Bruce Poppe Frank Speleman

Br J Haematol 2011 Aug 14;154(3):337-48. Epub 2011 May 14.

Centre for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08737.xDOI Listing
August 2011

Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist nutlin-3.

Authors:
Tom Van Maerken Ali Rihani Daniel Dreidax Sarah De Clercq Nurten Yigit Jean-Christophe Marine Frank Westermann Anne De Paepe Jo Vandesompele Frank Speleman

Mol Cancer Ther 2011 Jun 1;10(6):983-93. Epub 2011 Apr 1.

Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-1090DOI Listing
June 2011

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification.

Authors:
Sara De Brouwer Katleen De Preter Candy Kumps Piotr Zabrocki Michaël Porcu Ellen M Westerhout Arjan Lakeman Jo Vandesompele Jasmien Hoebeeck Tom Van Maerken Anne De Paepe Geneviève Laureys Johannes H Schulte Alexander Schramm Caroline Van Den Broecke Joëlle Vermeulen Nadine Van Roy Klaus Beiske Marleen Renard Rosa Noguera Olivier Delattre Isabelle Janoueix-Lerosey Per Kogner Tommy Martinsson Akira Nakagawara Miki Ohira Huib Caron Angelika Eggert Jan Cools Rogier Versteeg Frank Speleman

Clin Cancer Res 2010 Sep 18;16(17):4353-62. Epub 2010 Aug 18.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-2660DOI Listing
September 2010

A rapid and simple assay to determine pegylated erythropoietin in human serum.

Authors:
Tom Van Maerken Annemieke Dhondt Joris R Delanghe

J Appl Physiol (1985) 2010 Apr 21;108(4):800-3. Epub 2010 Jan 21.

Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1152/japplphysiol.01102.2009DOI Listing
April 2010

Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.

Authors:
Tom Van Maerken Liesbeth Ferdinande Jasmien Taildeman Irina Lambertz Nurten Yigit Liesbeth Vercruysse Ali Rihani Martin Michaelis Jindrich Cinatl Claude A Cuvelier Jean-Christophe Marine Anne De Paepe Marc Bracke Frank Speleman Jo Vandesompele

J Natl Cancer Inst 2009 Nov 10;101(22):1562-74. Epub 2009 Nov 10.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1093/jnci/djp355DOI Listing
November 2009

The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy.

Authors:
Nadine Van Roy Katleen De Preter Jasmien Hoebeeck Tom Van Maerken Filip Pattyn Pieter Mestdagh Joëlle Vermeulen Jo Vandesompele Frank Speleman

Genome Med 2009 Jul 27;1(7):74. Epub 2009 Jul 27.

Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm7
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http://dx.doi.org/10.1186/gm74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717400PMC
July 2009

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma.

Authors:
Tom Van Maerken Devanand Sarkar Frank Speleman Paul Dent William A Weiss Paul B Fisher

J Cell Physiol 2009 Jun;219(3):707-15

Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.1002/jcp.21719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921678PMC
June 2009

Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds.

Authors:
Katleen De Preter Sara De Brouwer Tom Van Maerken Filip Pattyn Alexander Schramm Angelika Eggert Jo Vandesompele Frank Speleman

Clin Cancer Res 2009 Jun 12;15(11):3690-6. Epub 2009 May 12.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-08-2699DOI Listing
June 2009

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma.

Authors:
Tom Van Maerken Frank Speleman Joëlle Vermeulen Irina Lambertz Sarah De Clercq Els De Smet Nurten Yigit Vicky Coppens Jan Philippé Anne De Paepe Jean-Christophe Marine Jo Vandesompele

Cancer Res 2006 Oct;66(19):9646-55

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-06-0792DOI Listing
October 2006

The role of serum erythropoietin levels in diagnosis and classification of erythrocytosis/polycythemia.

Authors:
Tom M A Van Maerken

Haematologica 2005 Nov;90 Suppl:ELT04; author reply ELT05

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November 2005

Familial and congenital polycythemias: a diagnostic approach.

Authors:
Tom Van Maerken Kathleen Hunninck Luc Callewaert Yves Benoit Geneviève Laureys Joris Verlooy

J Pediatr Hematol Oncol 2004 Jul;26(7):407-16

Department of Pediatric Hematology-Oncology, University Hospital Ghent, Belgium.

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July 2004