Tom Cupedo

Tom Cupedo

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Tom Cupedo

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Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells.

Cell Rep 2020 Jan;30(1):37-45.e3

Department of Hematology, Erasmus University Medical Center, 3000CA Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.115DOI Listing
January 2020

De novo generation of a functional human thymus from induced pluripotent stem cells.

J Allergy Clin Immunol 2019 Nov 16;144(5):1416-1419.e7. Epub 2019 Jul 16.

Department of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.05.042DOI Listing
November 2019

Frequencies of circulating regulatory TIGITCD38 effector T cells correlate with the course of inflammatory bowel disease.

Mucosal Immunol 2019 01 20;12(1):154-163. Epub 2018 Aug 20.

Laboratory of Pediatrics, division Gastroenterology and Nutrition, Erasmus University Medical Center-Sophia Children's Hospital, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41385-018-0078-4DOI Listing
January 2019

ILC2: at home in the thymus.

Authors:
Tom Cupedo

Eur J Immunol 2018 09;48(9):1441-1444

Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/eji.201847779DOI Listing
September 2018

IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes.

J Exp Med 2018 04 22;215(4):1069-1077. Epub 2018 Feb 22.

Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, England, UK

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http://dx.doi.org/10.1084/jem.20170518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881462PMC
April 2018

Review: Innate Lymphoid Cells: Sparking Inflammatory Rheumatic Disease?

Arthritis Rheumatol 2017 05;69(5):885-897

University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/art.40068DOI Listing
May 2017

Group 3 innate lymphoid cells in tissue damage and graft-versus-host disease pathogenesis.

Curr Opin Hematol 2016 07;23(4):410-5

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/MOH.0000000000000262DOI Listing
July 2016

Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice.

Eur J Immunol 2016 06 12;46(6):1404-14. Epub 2016 May 12.

Department of Rheumatology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/eji.201546241DOI Listing
June 2016

A Stromal Cell Niche for Human and Mouse Type 3 Innate Lymphoid Cells.

J Immunol 2015 Nov 16;195(9):4257-4263. Epub 2015 Sep 16.

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1402584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640183PMC
November 2015

Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage.

J Exp Med 2015 Oct 21;212(11):1783-91. Epub 2015 Sep 21.

Department of Hematology and Department of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center, 3015 CN Rotterdam, Netherlands

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http://dx.doi.org/10.1084/jem.20150318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612094PMC
October 2015

Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-κB-Inducing Kinase-Positive Endothelial Cells as Central Players.

Am J Pathol 2015 Jul 9;185(7):1935-43. Epub 2015 May 9.

Department of Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.03.012DOI Listing
July 2015

Progressive maturation toward hematopoietic stem cells in the mouse embryo aorta.

Blood 2015 Jan 9;125(3):465-9. Epub 2014 Oct 9.

Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences & University Medical Center Utrecht, Utrecht, The Netherlands; Department of Cell Biology and Department of Cell Biology, University Medical Center, Utrecht, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-07-58
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http://dx.doi.org/10.1182/blood-2014-07-588954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296008PMC
January 2015

Innate protection from graft-versus-host disease.

Authors:
Tom Cupedo

Blood 2014 Jul;124(5):673-5

ERASMUS UNIVERSITY MEDICAL CENTER.

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http://dx.doi.org/10.1182/blood-2014-06-578971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118481PMC
July 2014

Innate TCRs: single use only.

Nat Immunol 2014 Jan;15(1):12-3

Laboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ni.2792DOI Listing
January 2014

Characterization of Lgr5-positive epithelial cells in the murine thymus.

Eur J Immunol 2013 May 21;43(5):1243-51. Epub 2013 Mar 21.

Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/eji.201242947DOI Listing
May 2013

Dynamics of thymus organogenesis and colonization in early human development.

Development 2013 May;140(9):2015-26

MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, CRM Building, 5 Little France Drive, Edinburgh..

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http://dx.doi.org/10.1242/dev.087320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631974PMC
May 2013

Damage control: Rorγt+ innate lymphoid cells in tissue regeneration.

Curr Opin Immunol 2013 Apr 19;25(2):156-60. Epub 2013 Feb 19.

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.coi.2013.01.007DOI Listing
April 2013

Application of tissue engineering to the immune system: development of artificial lymph nodes.

Front Immunol 2012 16;3:343. Epub 2012 Nov 16.

Department of Hematology, Erasmus University Medical Center Rotterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2012.00343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499788PMC
November 2012

Innate lymphoid cells: emerging insights in development, lineage relationships, and function.

Annu Rev Immunol 2012 6;30:647-75. Epub 2012 Jan 6.

Tytgat Institute of Liver and Intestinal Research of the Academic Medical Center, Amsterdam 1105 AZ, The Netherlands.

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http://dx.doi.org/10.1146/annurev-immunol-020711-075053DOI Listing
July 2012

Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice.

Blood 2012 May 21;119(20):4723-30. Epub 2012 Feb 21.

Department of Hematology, Erasmus University Medical Center, Dr Molewaterplein 50, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-10-386359DOI Listing
May 2012

Rorγt+ innate lymphoid cells in intestinal homeostasis and immunity.

J Innate Immun 2011 5;3(6):577-84. Epub 2011 Sep 5.

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1159/000330668DOI Listing
March 2012

NK cells can generate from precursors in the adult human liver.

Eur J Immunol 2011 Nov 26;41(11):3340-50. Epub 2011 Sep 26.

Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.201141760DOI Listing
November 2011

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161.

Nat Immunol 2011 Sep 11;12(11):1055-62. Epub 2011 Sep 11.

Tytgat Institute for Liver and Intestinal Research, University of Amsterdam, Amsterdam, The Netherlands.

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http://www.nature.com/articles/ni.2104
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http://dx.doi.org/10.1038/ni.2104DOI Listing
September 2011

Human lymph node development: An inflammatory interaction.

Authors:
Tom Cupedo

Immunol Lett 2011 Jul 17;138(1):4-6. Epub 2011 Feb 17.

Department Hematology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.imlet.2011.02.008DOI Listing
July 2011

Activation and effector functions of human RORC+ innate lymphoid cells.

Curr Opin Immunol 2011 Jun 9;23(3):361-7. Epub 2011 May 9.

Department of Hematology, Erasmus University Medical Center, PO Box 2040, 3000CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.coi.2011.03.002DOI Listing
June 2011

An unexpected role for IL-17 in lymphoid organogenesis.

Authors:
Tom Cupedo

Nat Immunol 2011 Jun 20;12(7):590-2. Epub 2011 Jun 20.

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http://dx.doi.org/10.1038/ni.2058DOI Listing
June 2011

Thymic cysts originate from Foxn1 positive thymic medullary epithelium.

Mol Immunol 2010 Feb 27;47(5):1106-13. Epub 2009 Nov 27.

Laboratory for Lymphocyte Development, RIKEN Research Centre for Allergy and Immunology, Yokohama, Japan.

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http://dx.doi.org/10.1016/j.molimm.2009.10.034DOI Listing
February 2010

Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells.

J Exp Med 2010 Feb 8;207(2):281-90. Epub 2010 Feb 8.

Department of Immunology, Genentech, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1084/jem.20091509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822607PMC
February 2010

Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair?

Nat Rev Immunol 2009 04;9(4):229-34

Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, INSERM, U631, France.

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http://www.nature.com/articles/nri2522
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http://dx.doi.org/10.1038/nri2522DOI Listing
April 2009

Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells.

Nat Immunol 2009 Jan 23;10(1):66-74. Epub 2008 Nov 23.

Department of Hematology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ni.1668DOI Listing
January 2009

T cell-independent development and induction of somatic hypermutation in human IgM+ IgD+ CD27+ B cells.

J Exp Med 2008 Sep 11;205(9):2033-42. Epub 2008 Aug 11.

Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1084/jem.20070447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526198PMC
September 2008

Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner.

J Leukoc Biol 2008 Jul 10;84(1):152-61. Epub 2008 Apr 10.

Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0907659DOI Listing
July 2008

Development of human lymph nodes and Peyer's patches.

Semin Immunol 2008 Jun 18;20(3):164-70. Epub 2008 Apr 18.

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.smim.2008.02.003DOI Listing
June 2008

Transient accumulation of human mature thymocytes and regulatory T cells with CD28 superagonist in "human immune system" Rag2(-/-)gammac(-/-) mice.

Blood 2006 Jul 2;108(1):238-45. Epub 2006 Mar 2.

Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam (AMC-UvA), Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2006-01-0190DOI Listing
July 2006

Development and activation of regulatory T cells in the human fetus.

Eur J Immunol 2005 Feb;35(2):383-90

Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.200425763DOI Listing
February 2005

Cellular interactions in lymph node development.

J Immunol 2005 Jan;174(1):21-5

Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam, Vrije Universiteit Medical Center, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.174.1.21DOI Listing
January 2005

Induction of secondary and tertiary lymphoid structures in the skin.

Immunity 2004 Nov;21(5):655-67

Department of Molecular Cell Biology and Immunology, VU Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.immuni.2004.09.006DOI Listing
November 2004

Initiation of cellular organization in lymph nodes is regulated by non-B cell-derived signals and is not dependent on CXC chemokine ligand 13.

J Immunol 2004 Oct;173(8):4889-96

Department of Molecular Cell Biology and Immunology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.173.8.4889DOI Listing
October 2004

Presumptive lymph node organizers are differentially represented in developing mesenteric and peripheral nodes.

J Immunol 2004 Sep;173(5):2968-75

Department of Molecular Cell Biology and Immunology, Vrije University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.173.5.2968DOI Listing
September 2004

Role of chemokines in the development of secondary and tertiary lymphoid tissues.

Semin Immunol 2003 Oct;15(5):243-8

VU Medical Center, Department of Molecular Cell Biology, van der Boechorststraat 7, Amsterdam, BT 1081, The Netherlands.

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http://dx.doi.org/10.1016/j.smim.2003.08.002DOI Listing
October 2003

The role of CD45+CD4+CD3- cells in lymphoid organ development.

Immunol Rev 2002 Nov;189:41-50

VU Medical Center, Department of Molecular Cell Biology, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1034/j.1600-065x.2002.18905.xDOI Listing
November 2002