Publications by authors named "Toke Bek"

100Publications

Low educational level increases the incidence of vision-threatening diabetic retinopathy.

Authors:
Toke Bek

Dan Med J 2020 Sep 29;67(10). Epub 2020 Sep 29.

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September 2020

Differential Effects of Intra- and Extravascular ATP on the Diameter of Porcine Vessels at Different Branching Levels Ex Vivo.

Invest Ophthalmol Vis Sci 2020 Oct;61(12)

Department of Ophthalmology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

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http://dx.doi.org/10.1167/iovs.61.12.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552936PMC
October 2020

Oxygenation differs among white matter hyperintensities, intersected fiber tracts and unaffected white matter.

Brain Commun 2019 18;1(1):fcz033. Epub 2019 Nov 18.

Center of Functionally Integrative Neuroscience & MINDLab, Aarhus University Hospital, 8200 Aarhus C., Denmark.

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http://dx.doi.org/10.1093/braincomms/fcz033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425421PMC
November 2019

Systemic risk factors contribute differently to the development of proliferative diabetic retinopathy and clinically significant macular oedema.

Authors:
Toke Bek

Diabetologia 2020 Nov 21;63(11):2462-2470. Epub 2020 Jul 21.

Department of Ophthalmology, Aarhus University Hospital, DK-8200, Aarhus N, Denmark.

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http://dx.doi.org/10.1007/s00125-020-05234-0DOI Listing
November 2020

Is Early Blindness Protective of Psychosis or Are We Turning a Blind Eye to the Lack of Statistical Power?

Schizophr Bull 2020 Dec;46(6):1335-1336

Department of Affective Disorders, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1093/schbul/sbaa048DOI Listing
December 2020

Incidence and Risk for Developing Proliferative Diabetic Retinopathy after Photocoagulation for Diabetic Maculopathy.

Authors:
Toke Bek

Curr Eye Res 2020 08 10;45(8):986-991. Epub 2020 Jan 10.

Department of Ophthalmology, Aarhus University Hospital , Aarhus, Denmark.

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http://dx.doi.org/10.1080/02713683.2020.1712729DOI Listing
August 2020

Dilatation of Retinal Arterioles Induced by Topical Dorzolamide for One Week Is Impaired in Patients with Type 1 Diabetes and Mild Retinopathy.

Ophthalmologica 2020 5;243(3):236-242. Epub 2019 Dec 5.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1159/000504178DOI Listing
December 2019

The Oxygen Saturation in Vascular Abnormalities Depends on the Extent of Arteriovenous Shunting in Diabetic Retinopathy.

Invest Ophthalmol Vis Sci 2019 09;60(12):3762-3767

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1167/iovs.19-27472DOI Listing
September 2019

Reduced baseline diameter and contraction of peripheral retinal arterioles immediately after remote ischemia in diabetic patients.

Graefes Arch Clin Exp Ophthalmol 2019 Oct 4;257(10):2095-2101. Epub 2019 Jul 4.

Department of Ophthalmology, Aarhus University Hospital, 8200, Aarhus N, Denmark.

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http://dx.doi.org/10.1007/s00417-019-04407-xDOI Listing
October 2019

Retinal vessel reactivity is not attenuated in patients with type 2 diabetes compared with matched controls and is associated with peripheral endothelial function in controls.

J Diabetes Complications 2019 09 3;33(9):641-647. Epub 2019 Jun 3.

Department of Internal Medicine and Endocrinology, Aarhus University Hospital, DK-8200, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jdiacomp.2019.05.024DOI Listing
September 2019

Retinal vasodilatation in the affected eye but reduced pressure autoregulation of both eyes in unilateral Coats' disease.

Acta Ophthalmol 2019 Nov 6;97(7):679-683. Epub 2019 Mar 6.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.14073DOI Listing
November 2019

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy.

Mol Ther Nucleic Acids 2019 Jun 2;16:38-50. Epub 2019 Feb 2.

Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393707PMC
June 2019

Development and validation of a multiple-choice questionnaire-based theoretical test in direct ophthalmoscopy.

Acta Ophthalmol 2019 Nov 28;97(7):700-706. Epub 2019 Feb 28.

Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark.

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http://dx.doi.org/10.1111/aos.14065DOI Listing
November 2019

Translational research in retinal vascular disease. An approach.

Authors:
Toke Bek

Acta Ophthalmol 2019 Aug 22;97(5):441-450. Epub 2019 Feb 22.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, DK-8000, Denmark.

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http://dx.doi.org/10.1111/aos.14045DOI Listing
August 2019

The vasodilating effect of glucose differs among vessels at different branching level in the porcine retina ex vivo.

Exp Eye Res 2019 02 10;179:150-156. Epub 2018 Nov 10.

Department of Ophthalmology, Aarhus University Hospital, DK-8000, Aarhus C, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S00144835183052
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http://dx.doi.org/10.1016/j.exer.2018.11.006DOI Listing
February 2019

Retinal oxygen saturation is an independent risk factor for the severity of diabetic retinopathy.

Br J Ophthalmol 2019 08 18;103(8):1167-1172. Epub 2018 Oct 18.

Departments of Physiology, University of Iceland, Reykjavik, Iceland.

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3127
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http://dx.doi.org/10.1136/bjophthalmol-2018-312764DOI Listing
August 2019

Evidence-based Danish guidelines for screening of diabetic retinopathy.

Acta Ophthalmol 2018 Dec 11;96(8):763-769. Epub 2018 Oct 11.

Danish Ophthalmological Society, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/aos.13936DOI Listing
December 2018

The Retinal Oxygen Saturation Measured by Dual Wavelength Oximetry in Larger Retinal Vessels is Influenced by the Linear Velocity of the Blood.

Curr Eye Res 2019 01 5;44(1):46-52. Epub 2018 Oct 5.

a Department of Ophthalmology , Aarhus University Hospital , Aarhus C , Denmark.

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http://dx.doi.org/10.1080/02713683.2018.1524015DOI Listing
January 2019

Incidence and risk factors for neovascular age-related macular degeneration in the fellow eye.

Graefes Arch Clin Exp Ophthalmol 2018 Nov 10;256(11):2061-2068. Epub 2018 Aug 10.

Department of Ophthalmology, Aarhus University Hospital, 8000, Aarhus, Denmark.

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http://dx.doi.org/10.1007/s00417-018-4100-zDOI Listing
November 2018

Time to steroid treatment in severe acute optic neuritis.

Brain Behav 2018 08 22;8(8):e01032. Epub 2018 Jun 22.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1002/brb3.1032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085902PMC
August 2018

The area of fixation covaries with short-term changes in visual acuity after anti-vascular endothelial growth factor treatment in patients with diabetic macular oedema.

Acta Ophthalmol 2018 Nov 24;96(7):744-748. Epub 2018 Apr 24.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1111/aos.13773DOI Listing
November 2018

Age, sex, and type of medication predict the effect of anti-VEGF treatment on central retinal thickness in wet age-related macular degeneration.

Clin Ophthalmol 2018 8;12:473-479. Epub 2018 Mar 8.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.2147/OPTH.S158760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848666PMC
March 2018

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells.

Mol Ther Nucleic Acids 2017 Dec 21;9:89-99. Epub 2017 Sep 21.

Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2017.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626917PMC
December 2017

Is lack of autonomic nerves in retinal vessels a protection from electrical stimulation generated by activity in visual neurons?

Authors:
Toke Bek

Acta Ophthalmol 2018 03 2;96(2):e263. Epub 2017 Nov 2.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.13578DOI Listing
March 2018

The Diameter of Retinal Vessels Is Affected by Transient Ischemia of the Arm in Normal Persons.

Invest Ophthalmol Vis Sci 2017 10;58(12):5263-5269

Department of Ophthalmology, Aarhus University Hospital, Denmark.

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http://dx.doi.org/10.1167/iovs.17-22461DOI Listing
October 2017

ARTERIAL OXYGEN SATURATION IN NEOVASCULARIZATIONS IN PROLIFERATIVE DIABETIC RETINOPATHY.

Authors:
Toke Bek

Retina 2018 Dec;38(12):2301-2308

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1097/IAE.0000000000001870DOI Listing
December 2018

Activation of Veratridine Sensitive Sodium Channels, But not Electrical Field Stimulation, Dilates Porcine Retinal Arterioles with Preserved Perivascular Tissue.

Curr Eye Res 2017 11 14;42(11):1497-1502. Epub 2017 Sep 14.

a Department of Ophthalmology , Aarhus University Hospital , Aarhus C , Denmark.

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http://dx.doi.org/10.1080/02713683.2017.1337156DOI Listing
November 2017

Spatial distribution of early red lesions is a risk factor for development of vision-threatening diabetic retinopathy.

Diabetologia 2017 12 7;60(12):2361-2367. Epub 2017 Sep 7.

Department of Ophthalmology, Aarhus University Hospital, DK-8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s00125-017-4424-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449026PMC
December 2017

Diameter Changes of Retinal Vessels in Diabetic Retinopathy.

Authors:
Toke Bek

Curr Diab Rep 2017 08 8;17(10):82. Epub 2017 Aug 8.

Department of Ophthalmology, Aarhus University Hospital, 8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s11892-017-0909-9DOI Listing
August 2017

Post-hypoxic constriction of retinal arterioles is impaired during nitric oxide and cyclo-oxygenase inhibition and in diabetic patients without retinopathy.

Graefes Arch Clin Exp Ophthalmol 2017 Oct 27;255(10):1965-1971. Epub 2017 Jul 27.

Department of Ophthalmology, Aarhus University Hospital, DK-8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s00417-017-3746-2DOI Listing
October 2017

Binocular Fixation Reduces Fixational Eye Movements in the Worst Eye of Patients with Center-Involving Diabetic Macular Edema.

Ophthalmic Res 2017 7;58(3):142-149. Epub 2017 Jul 7.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1159/000476038DOI Listing
October 2017

Retinal Oxygen Saturation Correlates With Visual Acuity but Does Not Predict Outcome After Anti-VEGF Treatment in Central Retinal Vein Occlusion.

Invest Ophthalmol Vis Sci 2017 05;58(5):2498-2502

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1167/iovs.17-21532DOI Listing
May 2017

Differential effects of nitric oxide and cyclo-oxygenase inhibition on the diameter of porcine retinal vessels with different caliber during hypoxia ex vivo.

Exp Eye Res 2017 07 7;160:38-44. Epub 2017 Apr 7.

Department of Ophthalmology, Aarhus University Hospital, DK-8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.exer.2017.04.001DOI Listing
July 2017

Dissecting microRNA dysregulation in age-related macular degeneration: new targets for eye gene therapy.

Acta Ophthalmol 2018 Feb 7;96(1):9-23. Epub 2017 Mar 7.

Department of Biomedicine, Aarhus University, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.13407DOI Listing
February 2018

The role of retinopathy distribution and other lesion types for the definition of examination intervals during screening for diabetic retinopathy.

Acta Ophthalmol 2017 Jun 19;95(4):400-404. Epub 2016 Nov 19.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.13334DOI Listing
June 2017

Subretinal neovascularization as the only ocular sign of osteogenesis imperfecta: a case report.

Acta Ophthalmol 2017 Mar 19;95(2):e159-e160. Epub 2016 Nov 19.

Department of Ophthalmology, Aarhus University Hospital, Århus C, Denmark.

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http://dx.doi.org/10.1111/aos.13242DOI Listing
March 2017

Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone.

ChemMedChem 2016 10 13;11(20):2299-2310. Epub 2016 Sep 13.

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/cmdc.201600356DOI Listing
October 2016

The Systemic Blood Pressure and Oxygen Saturation in Retinal Arterioles Predict the Effect of Intravitreal Anti-VEGF Treatment on Diabetic Maculopathy.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5429-5434

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1167/iovs.16-20305DOI Listing
October 2016

Niels Ehlers 1930-2016.

Acta Ophthalmol 2016 Nov;94(7):637

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http://dx.doi.org/10.1111/aos.13268DOI Listing
November 2016

Lack of differences in the regional variation of oxygen saturation in larger retinal vessels in diabetic maculopathy and proliferative diabetic retinopathy.

Br J Ophthalmol 2017 06 23;101(6):752-757. Epub 2016 Aug 23.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1136/bjophthalmol-2016-308894DOI Listing
June 2017

The frequency of small saccades during fixation is age independent in children between 5 and 16 years of age.

Acta Ophthalmol 2017 Feb 18;95(1):79-84. Epub 2016 Aug 18.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1111/aos.13222DOI Listing
February 2017

Mitochondrial dysfunction and diabetic retinopathy.

Authors:
Toke Bek

Mitochondrion 2017 09 22;36:4-6. Epub 2016 Jul 22.

Department of Ophthalmology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2016.07.011DOI Listing
September 2017

The diameter response of retinal arterioles in diabetic maculopathy is reduced during hypoxia and is unaffected by the inhibition of cyclo-oxygenase and nitric oxide synthesis.

Graefes Arch Clin Exp Ophthalmol 2016 Dec 7;254(12):2339-2346. Epub 2016 Jun 7.

Department of Ophthalmology, Aarhus University Hospital, DK-8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s00417-016-3399-6DOI Listing
December 2016

The vasodilating effects of insulin and lactate are increased in precapillary arterioles in the porcine retina ex vivo.

Acta Ophthalmol 2016 Aug 24;94(5):454-62. Epub 2016 Mar 24.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.13025DOI Listing
August 2016

Aquaporin-1 Expression in Retinal Pigment Epithelial Cells Overlying Retinal Drusen.

Ophthalmic Res 2016 13;55(4):180-4. Epub 2016 Feb 13.

Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1159/000443207DOI Listing
October 2016

Tone regulation in giraffe retinal arterioles.

Acta Ophthalmol 2016 Sep 25;94(6):e523-4. Epub 2016 Jan 25.

Department of Biomedicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1111/aos.12958DOI Listing
September 2016

Preserved Pressure Autoregulation but Disturbed Cyclo-Oxygenase and Nitric Oxide Effects on Retinal Arterioles during Acute Hypoxia in Diabetic Patients without Retinopathy.

Ophthalmologica 2016 8;235(2):114-20. Epub 2016 Jan 8.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1159/000443147DOI Listing
October 2016

Lack of effect of nitroglycerin on the diameter response of larger retinal arterioles in normal persons during hypoxia.

Graefes Arch Clin Exp Ophthalmol 2016 Feb 30;254(2):277-83. Epub 2015 Nov 30.

Department of Ophthalmology, Aarhus University Hospital, DK-8000, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s00417-015-3227-4DOI Listing
February 2016

Purinergic mechanisms and prostaglandin E receptors involved in ATP-induced relaxation of porcine retinal arterioles in vitro.

Ophthalmic Res 2015 17;54(3):135-42. Epub 2015 Sep 17.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1159/000438905DOI Listing
April 2016

Prostaglandin induced changes in the tone of porcine retinal arterioles in vitro involve other factors than calcium activity in perivascular cells.

Exp Eye Res 2015 Sep 2;138:96-103. Epub 2015 Jul 2.

Department of Ophthalmology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.exer.2015.06.031DOI Listing
September 2015

Reoperation for rhegmatogenous retinal detachment as quality indicator for disease management: a register study.

Acta Ophthalmol 2015 Sep 1;93(6):505-11. Epub 2015 Jun 1.

Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark.

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http://dx.doi.org/10.1111/aos.12756DOI Listing
September 2015

Hypoxia-induced relaxation of porcine retinal arterioles in vitro depends on inducible NO synthase and EP4 receptor stimulation in the perivascular retina.

Acta Ophthalmol 2015 Aug 25;93(5):457-63. Epub 2015 Jan 25.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://doi.wiley.com/10.1111/aos.12669
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http://dx.doi.org/10.1111/aos.12669DOI Listing
August 2015

Diameter changes of retinal arterioles during acute hypoxia in vivo are modified by the inhibition of nitric oxide and prostaglandin synthesis.

Curr Eye Res 2015 Jul 8;40(7):737-43. Epub 2014 Sep 8.

Department of Ophthalmology, Aarhus University Hospital , Aarhus C, Aarhus , Denmark.

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http://dx.doi.org/10.3109/02713683.2014.954676DOI Listing
July 2015

Increasing oxygen saturation in larger retinal vessels after photocoagulation for diabetic retinopathy.

Invest Ophthalmol Vis Sci 2014 Aug 5;55(8):5365-9. Epub 2014 Aug 5.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1167/iovs.14-14811DOI Listing
August 2014

A nationwide study on the incidence of rhegmatogenous retinal detachment in Denmark, with emphasis on the risk of the fellow eye.

Retina 2014 Aug;34(8):1658-65

*Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark; and †Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1097/IAE.0000000000000104DOI Listing
August 2014

Fine structure in diabetic retinopathy lesions as observed by adaptive optics imaging. A qualitative study.

Authors:
Toke Bek

Acta Ophthalmol 2014 Dec 12;92(8):753-8. Epub 2014 Jun 12.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.12464DOI Listing
December 2014

Improvement of mild retinopathy in type 2 diabetic patients correlates with narrowing of retinal arterioles. A prospective observational study.

Graefes Arch Clin Exp Ophthalmol 2014 Oct 1;252(10):1561-7. Epub 2014 Apr 1.

Department of Ophthalmology, Aarhus University Hospital, 8000, Aarhus C, Denmark,

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http://dx.doi.org/10.1007/s00417-014-2614-6DOI Listing
October 2014

Dual effects of adenosine on the tone of porcine retinal arterioles in vitro.

Invest Ophthalmol Vis Sci 2014 Mar 19;55(3):1630-6. Epub 2014 Mar 19.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1167/iovs.13-13428DOI Listing
March 2014

Altered aquaporin expression in glaucoma eyes.

APMIS 2014 Sep 31;122(9):772-80. Epub 2014 Jan 31.

Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/apm.12225DOI Listing
September 2014

The oxygen saturation in retinal vessels from diabetic patients depends on the severity and type of vision-threatening retinopathy.

Acta Ophthalmol 2014 Feb 16;92(1):34-9. Epub 2013 Dec 16.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.12283DOI Listing
February 2014

Acute hyperinsulinemia increases the contraction of retinal arterioles induced by elevated blood pressure.

Am J Physiol Heart Circ Physiol 2013 Dec 20;305(11):H1600-4. Epub 2013 Sep 20.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark; and.

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http://dx.doi.org/10.1152/ajpheart.00560.2013DOI Listing
December 2013

Regional morphology and pathophysiology of retinal vascular disease.

Authors:
Toke Bek

Prog Retin Eye Res 2013 Sep 26;36:247-59. Epub 2013 Jul 26.

Department of Ophthalmology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.preteyeres.2013.07.002DOI Listing
September 2013

Relaxation of porcine retinal arterioles exposed to hypercholesterolemia in vivo is modified by hepatic LDL-receptor deficiency and diabetes mellitus.

Exp Eye Res 2013 Oct 24;115:79-86. Epub 2013 Jun 24.

Department of Ophthalmology, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2013.06.013DOI Listing
October 2013

Relaxation of porcine retinal arterioles during acute hypoxia in vitro depends on prostaglandin and NO synthesis in the perivascular retina.

Curr Eye Res 2013 Sep 14;38(9):965-71. Epub 2013 Jun 14.

Department of Ophthalmology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.3109/02713683.2013.794247DOI Listing
September 2013

Constriction of porcine retinal arterioles induced by endothelin-1 and the thromboxane analogue U46619 in vitro decreases with increasing vascular branching level.

Acta Ophthalmol 2014 May 7;92(3):232-7. Epub 2013 May 7.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1111/aos.12143DOI Listing
May 2014

Perivascular cells with pericyte characteristics are involved in ATP- and PGE(2)-induced relaxation of porcine retinal arterioles in vitro.

Invest Ophthalmol Vis Sci 2013 May 7;54(5):3258-64. Epub 2013 May 7.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1167/iovs.13-11685DOI Listing
May 2013

Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus.

Invest Ophthalmol Vis Sci 2013 Jan 21;54(1):636-40. Epub 2013 Jan 21.

Department of Ophthalmology, Aarhus University Hospital, Denmark.

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http://dx.doi.org/10.1167/iovs.12-11182DOI Listing
January 2013

Neurogenic contractions in intraocular porcine ciliary arteries are mediated by α₂-adrenoceptors and NPY₁ receptors and are inhibited by prostaglandin E₂ acting on prejunctional EP₄ receptors.

Exp Eye Res 2013 Feb 23;107:32-6. Epub 2012 Nov 23.

Department of Ophthalmology, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.exer.2012.11.008DOI Listing
February 2013

Aquaporins 6-12 in the human eye.

Acta Ophthalmol 2013 Sep 13;91(6):557-63. Epub 2012 Sep 13.

Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1755-3768.2012.02547.xDOI Listing
September 2013

[Eye complications in type 2 diabetes mellitus].

Authors:
Toke Bek

Ugeskr Laeger 2012 Sep;174(37):2147-50

Øjenafdelingen, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.

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September 2012

Dual effect of prostaglandins on isolated intraocular porcine ciliary arteries.

Acta Ophthalmol 2013 Sep 3;91(6):498-504. Epub 2012 Aug 3.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/j.1755-3768.2012.02479.xDOI Listing
September 2013

GABA-induced relaxation of porcine retinal arterioles in vitro depends on inhibition from the perivascular retina and is mediated by GABAC receptors.

Invest Ophthalmol Vis Sci 2012 Jun 5;53(7):3309-15. Epub 2012 Jun 5.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1167/iovs.12-9838DOI Listing
June 2012

[Limited value of ophthalmoscopy in arterial hypertension].

Authors:
Toke Bek

Ugeskr Laeger 2011 Oct;173(43):2709-10

Øjenafdelingen, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.

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October 2011

Topical treatment for 1 week with latanoprost but not diclofenac reduces the diameter of dilated retinal arterioles in patients with type 1 diabetes mellitus and mild retinopathy.

Acta Ophthalmol 2012 Dec 5;90(8):750-5. Epub 2011 Jul 5.

Department of Ophthalmology, Århus University Hospital, Århus C, Denmark.

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http://doi.wiley.com/10.1111/j.1755-3768.2011.02185.x
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http://dx.doi.org/10.1111/j.1755-3768.2011.02185.xDOI Listing
December 2012

The predictive value of subjective symptoms and clinical signs for the presence of treatment-requiring exudative age-related macular degeneration.

Acta Ophthalmol 2012 Aug 14;90(5):471-5. Epub 2011 Jan 14.

Department of Ophthalmology, Århus University Hospital, Århus C, Denmark.

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http://dx.doi.org/10.1111/j.1755-3768.2010.02074.xDOI Listing
August 2012

Differential diameter responses in macular and peripheral retinal arterioles may contribute to the regional distribution of diabetic retinopathy lesions.

Graefes Arch Clin Exp Ophthalmol 2011 Mar 11;249(3):407-12. Epub 2010 Nov 11.

Department of Ophthalmology, Århus University Hospital, DK-8000, Århus C, Denmark.

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http://link.springer.com/10.1007/s00417-010-1549-9
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http://dx.doi.org/10.1007/s00417-010-1549-9DOI Listing
March 2011

Lack of correlation between short-term dynamics of diabetic retinopathy lesions and the arterial blood pressure.

Authors:
Toke Bek

Graefes Arch Clin Exp Ophthalmol 2011 Feb 3;249(2):267-71. Epub 2010 Oct 3.

Department of Ophthalmology, Århus University Hospital, DK-8000, Århus C, Denmark.

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http://link.springer.com/10.1007/s00417-010-1525-4
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http://dx.doi.org/10.1007/s00417-010-1525-4DOI Listing
February 2011

[Unspecific effects of certain siRNA molecules used in the treatment of age related macular degeneration].

Ugeskr Laeger 2010 Sep;172(36):2457-9

Aarhus Universitet, Center for Bioetik og Nanoetik, Denmark.

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September 2010

Novel cellular bouton structure activated by ATP in the vascular wall of porcine retinal arterioles.

Invest Ophthalmol Vis Sci 2010 Dec 4;51(12):6681-7. Epub 2010 Aug 4.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1167/iovs.10-5753DOI Listing
December 2010

Voltage-gated calcium channels are involved in the regulation of calcium oscillations in vascular smooth muscle cells from isolated porcine retinal arterioles.

Exp Eye Res 2010 Jul 20;91(1):69-75. Epub 2010 Apr 20.

Aarhus University Hospital, Department of Ophthalmology, Norrebrogade 44, 8000 Aarhus C, Denmark.

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http://linkinghub.elsevier.com/retrieve/pii/S001448351000114
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http://dx.doi.org/10.1016/j.exer.2010.04.003DOI Listing
July 2010

Individualized optimization of the screening interval for diabetic retinopathy: a new model.

Acta Ophthalmol 2012 Mar 6;90(2):109-14. Epub 2010 Apr 6.

Department of Ophthalmology, Aarhus University Hospital, DK- 8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1111/j.1755-3768.2010.01882.xDOI Listing
March 2012