Publications by authors named "Toin H van Kuppevelt"

100Publications

Oncolytic Virus Therapy with HSV-1 for Hematological Malignancies.

Mol Ther 2020 Sep 30. Epub 2020 Sep 30.

Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2020.09.041DOI Listing
September 2020

Construction and evaluation of an antibody phage display library targeting heparan sulfate.

Glycoconj J 2020 08 28;37(4):445-455. Epub 2020 May 28.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud university medical center, PO Box 9101, 6500, HB, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1007/s10719-020-09925-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329785PMC
August 2020

Introduction of Specific 3D Micromorphologies in Collagen Scaffolds Using Odd and Even Dicarboxylic Acids.

ACS Omega 2020 Mar 18;5(8):3908-3916. Epub 2020 Feb 18.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/acsomega.9b03350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057318PMC
March 2020

Sustained Postnatal Skin Regeneration Upon Prenatal Application of Functionalized Collagen Scaffolds.

Tissue Eng Part A 2020 Jan 22. Epub 2020 Jan 22.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1089/ten.tea.2019.0234DOI Listing
January 2020

Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.

Cancer Biomark 2019 ;25(3):233-241

Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, the Netherlands.

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http://dx.doi.org/10.3233/CBM-181826DOI Listing
January 2020

A versatile salt-based method to immobilize glycosaminoglycans and create growth factor gradients.

Glycoconj J 2019 06 4;36(3):227-236. Epub 2019 May 4.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud university medical center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10719-019-09872-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548755PMC
June 2019

Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.

Int J Gynecol Pathol 2020 Mar;39(2):184-192

Departments of Obstetrics and Gynaecology (M.C.V., E.H.) Pathology, Elisabeth-Tweesteden Hospital (E.H., A.A.M.v.d.W.), LC Tilburg Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre (S.C.H.A.v.d.S., T.H.V.K.) Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre (S.C.H.A.v.d.S., L.F.A.G.M.), HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/PGP.0000000000000587DOI Listing
March 2020

Muscle fibrosis in the soft palate: Delivery of cells, growth factors and anti-fibrotics.

Adv Drug Deliv Rev 2019 06 11;146:60-76. Epub 2018 Aug 11.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, P.O. Box 9101, 6500HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.08.002DOI Listing
June 2019

Self-expandable tubular collagen implants.

J Tissue Eng Regen Med 2018 06 15;12(6):1494-1498. Epub 2018 May 15.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/term.2685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032829PMC
June 2018

Chemotherapeutic drug delivery by tumoral extracellular matrix targeting.

J Control Release 2018 03 31;274:1-8. Epub 2018 Jan 31.

Radboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2018.01.029DOI Listing
March 2018

Unidirectional BMP2-loaded collagen scaffolds induce chondrogenic differentiation.

Biomed Mater 2017 Nov 22;13(1):015007. Epub 2017 Nov 22.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1088/1748-605X/aa8960DOI Listing
November 2017

Sequencing of glycosaminoglycans with potential to interrogate sequence-specific interactions.

Sci Rep 2017 11 1;7(1):14785. Epub 2017 Nov 1.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud university medical center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-15009-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665995PMC
November 2017

Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation.

Sci Rep 2017 10 23;7(1):13847. Epub 2017 Oct 23.

Department of Molecular Neurobiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Ibaraki, 305-8575, Japan.

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http://dx.doi.org/10.1038/s41598-017-14185-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653861PMC
October 2017

Membrane permeation of arginine-rich cell-penetrating peptides independent of transmembrane potential as a function of lipid composition and membrane fluidity.

J Control Release 2017 06 12;256:68-78. Epub 2017 Apr 12.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 28, 6525 GA Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.04.013DOI Listing
June 2017

Tissue Engineering of the Urethra: A Systematic Review and Meta-analysis of Preclinical and Clinical Studies.

Eur Urol 2017 10 4;72(4):594-606. Epub 2017 Apr 4.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.03.026DOI Listing
October 2017

Changes in the Extracellular Matrix Are Associated With the Development of Serous Tubal Intraepithelial Carcinoma Into High-Grade Serous Carcinoma.

Int J Gynecol Cancer 2017 07;27(6):1072-1081

*Department of Obstetrics and Gynaecology, Radboud University Medical Center; †Department of Biochemistry, Radboud Institute for Molecular Life Sciences; ‡Department of Pathology, Radboud University Medical Center, Nijmegen; and §Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/IGC.0000000000000933DOI Listing
July 2017

Bladder Regeneration Using Multiple Acellular Scaffolds with Growth Factors in a Bladder.

Tissue Eng Part A 2018 01 2;24(1-2):11-20. Epub 2017 May 2.

1 Department of Urology, Radboudumc Amalia Children's Hospital, Radboud University Medical Center , Nijmegen, The Netherlands .

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http://dx.doi.org/10.1089/ten.TEA.2016.0356DOI Listing
January 2018

Tubular collagen scaffolds with radial elasticity for hollow organ regeneration.

Acta Biomater 2017 04 5;52:1-8. Epub 2017 Feb 5.

Department of Biochemistry, Radboud Institute for Molecular Life Science, Radboud University Medical Center, Geert Grooteplein 26-28, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2017.02.005DOI Listing
April 2017

A potential role for chondroitin sulfate/dermatan sulfate in arm regeneration in Amphiura filiformis.

Glycobiology 2017 05;27(5):438-449

Department of Medical Biochemistry and Microbiology, The Biomedical Center, Uppsala University, Box 582, SE-751 23 Uppsala, Sweden.

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http://dx.doi.org/10.1093/glycob/cwx010DOI Listing
May 2017

Evaluation of cultured human dermal- and dermo-epidermal substitutes focusing on extracellular matrix components: Comparison of protein and RNA analysis.

Burns 2017 May 29;43(3):520-530. Epub 2016 Dec 29.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 28, 6525 GA, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03054179163042
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http://dx.doi.org/10.1016/j.burns.2016.10.002DOI Listing
May 2017

Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes.

Eur J Pharm Biopharm 2017 Apr 26;113:229-239. Epub 2016 Dec 26.

Department of Biochemistry, Radboud university medical center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejpb.2016.12.010DOI Listing
April 2017

Increased deposition of glycosaminoglycans and altered structure of heparan sulfate in idiopathic pulmonary fibrosis.

Int J Biochem Cell Biol 2017 02 11;83:27-38. Epub 2016 Dec 11.

Department of Experimental Medical Sciences, Lund University, Sweden; Department of Respiratory Medicine and Allergology, Lund University, Sweden,. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.12.005DOI Listing
February 2017

Improved cartilage regeneration by implantation of acellular biomaterials after bone marrow stimulation: a systematic review and meta-analysis of animal studies.

PeerJ 2016 8;4:e2243. Epub 2016 Sep 8.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.7717/peerj.2243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018675PMC
September 2016

MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.

J Ovarian Res 2016 Sep 2;9(1):53. Epub 2016 Sep 2.

Department of Obstetrics and Gynecology, Radboud University Medical Centre, PO Box 9101, 6500, HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13048-016-0262-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010680PMC
September 2016

Cathepsin L is crucial for the development of early experimental diabetic nephropathy.

Kidney Int 2016 11 26;90(5):1012-1022. Epub 2016 Aug 26.

Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.06.035DOI Listing
November 2016

Design of an elasticized collagen scaffold: A method to induce elasticity in a rigid protein.

Acta Biomater 2016 10 21;44:277-85. Epub 2016 Aug 21.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 26-28, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.08.038DOI Listing
October 2016

Scaffolds for whole organ tissue engineering: Construction and in vitro evaluation of a seamless, spherical and hollow collagen bladder construct with appendices.

Acta Biomater 2016 10 14;43:112-121. Epub 2016 Jul 14.

Department of Biochemistry 280, Radboud Institute for Molecular Life Sciences, Radboud university medical center, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.07.022DOI Listing
October 2016

Altered interaction and distribution of glycosaminoglycans and growth factors in mucopolysaccharidosis type I bone disease.

Bone 2016 07 19;88:92-100. Epub 2016 Apr 19.

Laboratory of Genetic Metabolic Diseases, Department of Clinical Chemistry and Pediatrics, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands; Department of Pediatrics and Amsterdam Lysosome Centre "Sphinx", Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.01.029DOI Listing
July 2016

GRP75 upregulates clathrin-independent endocytosis through actin cytoskeleton reorganization mediated by the concurrent activation of Cdc42 and RhoA.

Exp Cell Res 2016 05 22;343(2):223-236. Epub 2016 Apr 22.

Department of Biochemistry & Cell Biology, School of Medicine, Nankai University, Tianjin, PR China; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2016.04.009DOI Listing
May 2016

Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer.

Diagn Pathol 2016 Apr 2;11:34. Epub 2016 Apr 2.

Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13000-016-0485-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818939PMC
April 2016

N-sulfation of heparan sulfate is critical for syndecan-4-mediated podocyte cell-matrix interactions.

Am J Physiol Renal Physiol 2016 05 2;310(10):F1123-35. Epub 2016 Mar 2.

Department of Cell Biology and Anatomy, LSU Health Sciences Center, Shreveport, Louisiana; Department of Pathology, LSU Health Sciences Center, Shreveport, Louisiana; and

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http://dx.doi.org/10.1152/ajprenal.00603.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002056PMC
May 2016

Novel tubular constructs for urinary diversion: a biocompatibility study in pigs.

J Tissue Eng Regen Med 2017 08 16;11(8):2241-2249. Epub 2016 Feb 16.

Department of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/term.2122DOI Listing
August 2017

Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis.

Am J Pathol 2016 Apr 9;186(4):805-15. Epub 2016 Feb 9.

Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.12.008DOI Listing
April 2016

Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.

Am J Physiol Renal Physiol 2016 Mar 13;310(5):F395-408. Epub 2016 Jan 13.

Kidney and Vascular Pathology, Faculty of Medicine and Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan;

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http://dx.doi.org/10.1152/ajprenal.00445.2015DOI Listing
March 2016

Visualisation of newly synthesised collagen in vitro and in vivo.

Sci Rep 2016 Jan 7;6:18780. Epub 2016 Jan 7.

Radboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/srep18780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704054PMC
January 2016

Prognostic significance of highly sulfated chondroitin sulfates in ovarian cancer defined by the single chain antibody GD3A11.

Gynecol Oncol 2016 Mar 28;140(3):527-36. Epub 2015 Dec 28.

Department of Obstetrics and Gynaecology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ygyno.2015.12.024DOI Listing
March 2016

Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro.

J Biol Chem 2016 Mar 4;291(10):4974-81. Epub 2016 Jan 4.

From the Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands,

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http://dx.doi.org/10.1074/jbc.M115.702506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777835PMC
March 2016

Drug delivery systems for ovarian cancer treatment: a systematic review and meta-analysis of animal studies.

PeerJ 2015 10;3:e1489. Epub 2015 Dec 10.

Department of Biochemistry, Radboud university medical center , Nijmegen , The Netherlands.

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http://dx.doi.org/10.7717/peerj.1489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690347PMC
December 2015

ERRATUM TO: Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.

Methods Mol Biol 2015 ;1324:E1

Department of Biochemistry, Radboud University Medical Center, Geert Grooteplein 28, 6525, GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-2806-4_32DOI Listing
October 2015

Bladder Regeneration Using a Smart Acellular Collagen Scaffold with Growth Factors VEGF, FGF2 and HB-EGF.

Tissue Eng Part A 2016 Jan 1;22(1-2):83-92. Epub 2015 Dec 1.

1 Department of Urology Radboudumc Amalia Children's Hospital, Radboud University Medical Center , Nijmegen, The Netherlands .

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http://dx.doi.org/10.1089/ten.TEA.2015.0096DOI Listing
January 2016

Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology.

PLoS One 2015 31;10(9):e0134946. Epub 2015 Aug 31.

Nephrology Research Laboratory, Radboud Institute for Molecular Life Sciences, Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556443PMC
May 2016

Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.

ACS Chem Biol 2015 Oct 10;10(10):2353-63. Epub 2015 Aug 10.

Cluster for Molecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen , Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/acschembio.5b00501DOI Listing
October 2015

Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma.

Cell Signal 2015 Oct 23;27(10):2054-67. Epub 2015 Jul 23.

Karolinska Institutet, Department of Laboratory Medicine, Division of Pathology, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.cellsig.2015.07.017DOI Listing
October 2015

Vitamin D attenuates proteinuria by inhibition of heparanase expression in the podocyte.

J Pathol 2015 Dec 31;237(4):472-81. Epub 2015 Aug 31.

Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/path.4593DOI Listing
December 2015

Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.

Methods Mol Biol 2015 ;1324:123-31

Department of Biochemistry, Radboud University Medical Center, Geert Grooteplein 28, 6525, GA, Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-2806-4_8
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http://dx.doi.org/10.1007/978-1-4939-2806-4_8DOI Listing
April 2016

Interactions between Skeletal Muscle Myoblasts and their Extracellular Matrix Revealed by a Serum Free Culture System.

PLoS One 2015 1;10(6):e0127675. Epub 2015 Jun 1.

School of Biomedical Science, CHIRI Biosciences Research Precinct, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127675PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450880PMC
March 2016

Biodistribution of size-selected lyophilisomes in mice.

Eur J Pharm Biopharm 2015 Aug 5;94:141-51. Epub 2015 May 5.

Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2015.04.020DOI Listing
August 2015

A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3).

FASEB J 2015 Jul 13;29(7):2993-3002. Epub 2015 Apr 13.

*Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Department of Synthetic Organic Chemistry, Institute for Molecules and Materials, and Department of Neurology, Laboratory for Genetic, Endocrine and Metabolic Disease, Radboud University Medical Centre, Nijmegen, The Netherlands; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, and Glycotechnology Core, University of California San Diego, San Diego, California, USA; and Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Centre, Amsterdam, The Netherlands

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http://dx.doi.org/10.1096/fj.14-264226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478805PMC
July 2015

Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis.

Kidney Int 2015 Nov 8;88(5):990-8. Epub 2015 Apr 8.

Department of Internal Medicine II, Nephrology and Clinical Immunology, RWTH Aachen University Hospital, Aachen, Germany.

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http://dx.doi.org/10.1038/ki.2015.116DOI Listing
November 2015

HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.

Brain 2015 May 4;138(Pt 5):1339-54. Epub 2015 Apr 4.

1 Laboratory Cell Growth, Tissue Repair and Regeneration (CRRET), Centre National de la Recherche Scientifique (CNRS) EA UPEC 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, F-94000, Créteil, France

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http://dx.doi.org/10.1093/brain/awv056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963411PMC
May 2015

Versatile wedge-based system for the construction of unidirectional collagen scaffolds by directional freezing: practical and theoretical considerations.

ACS Appl Mater Interfaces 2015 Apr 14;7(16):8495-505. Epub 2015 Apr 14.

†Department of Biochemistry 280, Radboud Institute for Molecular Life Sciences, Radboud university medical center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/acsami.5b00169DOI Listing
April 2015

Directing collagen fibers using counter-rotating cone extrusion.

Acta Biomater 2015 Jan 16;12:113-121. Epub 2014 Oct 16.

Department of Biochemistry 280, RIMLS, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, Netherlands.

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http://dx.doi.org/10.1016/j.actbio.2014.10.012DOI Listing
January 2015

Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth.

Exp Cell Res 2015 Jan 13;330(2):358-370. Epub 2014 Nov 13.

Department of Surgery, Walter-Reed National Military Medical Center, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1016/j.yexcr.2014.11.002DOI Listing
January 2015

Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I.

J Biol Chem 2014 Dec 30;289(52):36194-203. Epub 2014 Oct 30.

From the Stem Cell & Neurotherapies Group, Faculty of Medical and Human Sciences, University of Manchester, Manchester M13 9PT, United Kingdom,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.599944
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http://dx.doi.org/10.1074/jbc.M114.599944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276882PMC
December 2014

Use of flow cytometry for characterization and fractionation of cell populations based on their expression of heparan sulfate epitopes.

Methods Mol Biol 2015 ;1229:239-51

Wellcome Trust Centre for Cell Matrix Research, Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1007/978-1-4939-1714-3_21DOI Listing
June 2015

Sulfated sugars in the extracellular matrix orchestrate ovarian cancer development: 'when sweet turns sour'.

Gynecol Oncol 2014 Nov 23;135(2):371-81. Epub 2014 Aug 23.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ygyno.2014.08.023DOI Listing
November 2014

Novel single-chain antibody GD3A10 defines a chondroitin sulfate biomarker for ovarian cancer.

Biomark Med 2014 ;8(5):699-711

Department of Biochemistry, Nijmegen Center for Molecular Life Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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August 2015

Glycosaminoglycan modifications in Duchenne muscular dystrophy: specific remodeling of chondroitin sulfate/dermatan sulfate.

J Neuropathol Exp Neurol 2014 Aug;73(8):789-97

From the INSERM U972, Paul Brousse Hospital, Villejuif (EN, FC, GU); and EAC CNRS 7149, CRRET Laboratory, Sciences and Technology Faculty, Paris-Est Creteil University, Créteil (EH, FC, MG-S, DP-G, PA), France; and Department of Biochemistry (280), Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands (THVK).

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https://academic.oup.com/jnen/article-lookup/doi/10.1097/NEN
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http://dx.doi.org/10.1097/NEN.0000000000000098DOI Listing
August 2014

'Immunosequencing' of heparan sulfate from human cell lines and rat kidney: the (GlcNS6S-IdoA2S)₃ motif, recognized by antibody NS4F5, is located towards the non-reducing end.

Biochem J 2014 Aug;461(3):461-8

*Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Geert Grooteplein 26-28, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1042/BJ20140355DOI Listing
August 2014

Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis.

Kidney Int 2014 Nov 23;86(5):932-42. Epub 2014 Apr 23.

Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ki.2014.115DOI Listing
November 2014

Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling.

PLoS One 2014 25;9(3):e92381. Epub 2014 Mar 25.

Ann and Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, Illinois, United States of America; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965413PMC
January 2015

Immunohistochemical expression of MMP-14 and MMP-2, and MMP-2 activity during human ovarian follicular development.

Reprod Biol Endocrinol 2014 Jan 31;12:12. Epub 2014 Jan 31.

Department of Obstetrics and Gynaecology, St, Elisabeth Hospital, PO Box 90151, 5000 LC Tilburg, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937151PMC
January 2014

Specific targeting of tumor cells by lyophilisomes functionalized with antibodies.

Eur J Pharm Biopharm 2014 May 23;87(1):80-9. Epub 2014 Jan 23.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2014.01.005DOI Listing
May 2014

Is there a need for smooth muscle cell transplantation in urethral reconstruction?

Tissue Eng Part A 2014 May 6;20(9-10):1542-9. Epub 2014 Feb 6.

1 Department of Urology, Karl-Eberhard University of Tübingen , Tübingen, Germany .

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http://dx.doi.org/10.1089/ten.TEA.2013.0185DOI Listing
May 2014

The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides.

Cell Mol Life Sci 2014 Jul 24;71(14):2717-29. Epub 2013 Nov 24.

Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Geert Grooteplein 28, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00018-013-1517-8DOI Listing
July 2014

Heparan sulfate in angiogenesis: a target for therapy.

Angiogenesis 2014 Jul 22;17(3):443-62. Epub 2013 Oct 22.

Department of Biochemistry (280), Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, PO. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10456-013-9401-6DOI Listing
July 2014

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity.

Proc Natl Acad Sci U S A 2013 Oct 7;110(43):17380-5. Epub 2013 Oct 7.

Department of Clinical Sciences, Section of Oncology, Lund University, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1073/pnas.1304266110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808637PMC
October 2013

Similar hyaline-like cartilage repair of osteochondral defects in rabbits using isotropic and anisotropic collagen scaffolds.

Tissue Eng Part A 2014 Feb 19;20(3-4):635-45. Epub 2013 Oct 19.

1 Orthopaedic Research Lab, Department of Orthopaedics, Radboud University Nijmegen Medical Centre , Nijmegen, The Netherlands .

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http://dx.doi.org/10.1089/ten.TEA.2013.0083DOI Listing
February 2014

Podocyte-specific deletion of NDST1, a key enzyme in the sulfation of heparan sulfate glycosaminoglycans, leads to abnormalities in podocyte organization in vivo.

Kidney Int 2014 Feb 7;85(2):307-18. Epub 2013 Aug 7.

1] Department of Cell Biology and Anatomy, LSU Health Sciences Center, Shreveport, Louisiana, USA [2] Department of Pathology, LSU Health Sciences Center, Shreveport, Louisiana, USA.

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http://dx.doi.org/10.1038/ki.2013.281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624314PMC
February 2014

Heparinized collagen scaffolds with and without growth factors for the repair of diaphragmatic hernia: construction and in vivo evaluation.

Organogenesis 2013 Jul-Sep;9(3):161-7. Epub 2013 Jul 18.

Department of Biochemistry; NCMLS; Radboud University Nijmegen Medical Centre; Nijmegen, The Netherlands.

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http://dx.doi.org/10.4161/org.25587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896586PMC
June 2014

Heparin increases the infectivity of Human Papillomavirus type 16 independent of cell surface proteoglycans and induces L1 epitope exposure.

Cell Microbiol 2013 Nov 6;15(11):1818-36. Epub 2013 May 6.

Emmy-Noether Group 'Virus Endocytosis', Institutes of Molecular Virology and Medical Biochemistry, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1111/cmi.12150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731924PMC
November 2013

Construction and in vivo evaluation of a dual layered collagenous scaffold with a radial pore structure for repair of the diaphragm.

Acta Biomater 2013 Jun 14;9(6):6844-51. Epub 2013 Mar 14.

Department of Biochemistry, 280, NCMLS, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S17427061130012
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June 2013