Publications

Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.
Mol Pharmacol 2014 Sep 23;86(3):252-62. Epub 2014 Jun 23.
Department of Pharmacology, University of Illinois at Chicago College of Medicine, Chicago, Illinois (M.P., A.V.K., T.Ko.); Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia (T. Ka.); and Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (N.S., T.H., T.Ko.).



Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity.
Sci Signal 2010 May 11;3(121):ra37. Epub 2010 May 11.
Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface.
J Biol Chem 2009 Feb 12;284(8):5000-9. Epub 2008 Dec 12.
Laboratory of Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.



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