Todd Mainprize

Todd Mainprize

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Todd Mainprize

Todd Mainprize

Publications by authors named "Todd Mainprize"

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Adverse Radiation Effect After Hypofractionated Stereotactic Radiosurgery in 5 Daily Fractions for Surgical Cavities and Intact Brain Metastases.

Int J Radiat Oncol Biol Phys 2020 03 9;106(4):772-779. Epub 2020 Jan 9.

Department of Radiation Oncology, University of Toronto, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ijrobp.2019.12.002DOI Listing
March 2020

Image-Guided, Linac-Based, Surgical Cavity-Hypofractionated Stereotactic Radiotherapy in 5 Daily Fractions for Brain Metastases.

Neurosurgery 2019 11;85(5):E860-E869

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1093/neuros/nyz162DOI Listing
November 2019

First-in-human trial of blood-brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound.

Nat Commun 2019 09 26;10(1):4373. Epub 2019 Sep 26.

Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, M4N 3M5, Canada.

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http://dx.doi.org/10.1038/s41467-019-12426-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763482PMC
September 2019

Optical Topographic Imaging for Spinal Intraoperative Three-Dimensional Navigation in Mini-Open Approaches: A Prospective Cohort Study of Initial Preclinical and Clinical Feasibility.

World Neurosurg 2019 05 8;125:e863-e872. Epub 2019 Feb 8.

Division of Neurosurgery, Department of Surgery, University of Toronto. Toronto, Toronto, Ontario, Canada; Institute of Medical Science, School of Graduate Studies, University of Toronto. Toronto, Toronto, Ontario, Canada; Biophotonics and Bioengineering Laboratory, Sunnybrook Health Sciences Centre. Toronto, Toronto, Ontario, Canada; Department of Electrical and Computer Engineering, Ryerson University, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.wneu.2019.01.201DOI Listing
May 2019

Utilization of Spinal Intra-operative Three-dimensional Navigation by Canadian Surgeons and Trainees: A Population-based Time Trend Study.

Can J Neurol Sci 2019 01;46(1):87-95

1Division of Neurosurgery,Department of Surgery,University of Toronto,Toronto,Ontario,Canada.

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http://dx.doi.org/10.1017/cjn.2018.376DOI Listing
January 2019

Somatosensory evoked potentials after decompressive craniectomy for traumatic brain injury.

J Clin Monit Comput 2018 Oct 30;32(5):881-887. Epub 2017 Nov 30.

Division of Neurosurgery, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.

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http://dx.doi.org/10.1007/s10877-017-0083-2DOI Listing
October 2018

High-Intensity Focused Ultrasound Ablation Therapy of Gliomas.

Prog Neurol Surg 2018 10;32:39-47. Epub 2018 Jul 10.

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http://dx.doi.org/10.1159/000469678DOI Listing
October 2018

Hypoxia Detection in Infiltrative Astrocytoma: Ferumoxytol-based Quantitative BOLD MRI with Intraoperative and Histologic Validation.

Radiology 2018 09 26;288(3):821-829. Epub 2018 Jun 26.

From the Department of Medical Imaging (P.J.M., A.B., S.S., Z.F.D., A.C., P.A.L., O.S., D.M.), Division of Neurosurgery (S.D., T.M., R.J.), Department of Laboratory Medicine and Pathobiology (J.K., D.G.M.), Department of Radiation Oncology (A.S.), Division of Neurology (S.I.), and Department of Biostatistics (E.G.A.), University of Toronto, 263 McCaul St, 4th Floor, Toronto, ON, Canada M5T 1W7; Department of Neurosurgery, Joan C. Edwards School of Medicine, Huntington, WV (N.P.); Department of Mechanical Engineering, Australian College of Kuwait, Kuwait City, Kuwait (A.E.); Department of Physics, Ryerson University, Toronto, Canada (R.J.); and Department of Radiology, Stanford University School of Medicine, Stanford, Calif (G.Z.).

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http://dx.doi.org/10.1148/radiol.2018172601DOI Listing
September 2018

An Algorithm for Managing Intraosseous Vascular Anomalies of the Craniofacial Skeleton.

J Craniofac Surg 2018 May;29(3):622-627

Division of Plastic and Reconstructive Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.1097/SCS.0000000000004014DOI Listing
May 2018

To frame or not to frame? Cone-beam CT-based analysis of head immobilization devices specific to linac-based stereotactic radiosurgery and radiotherapy.

J Appl Clin Med Phys 2018 Mar 24;19(2):111-120. Epub 2018 Jan 24.

Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/acm2.12251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849846PMC
March 2018

Stereotactic radiosurgery for resected brain metastasis: Cavity dynamics and factors affecting its evolution.

J Radiosurg SBRT 2018 ;5(3):191-200

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018046PMC
January 2018

Structure, Process, and Culture of Intensive Care Units Treating Patients with Severe Traumatic Brain Injury: Survey of Centers Participating in the American College of Surgeons Trauma Quality Improvement Program.

J Neurotrauma 2017 10 17;34(19):2760-2767. Epub 2017 May 17.

1 Sunnybrook Research Institute , Sunnybrook Health Sciences Center, Toronto, Ontario, Canada .

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http://dx.doi.org/10.1089/neu.2017.4997DOI Listing
October 2017

Optimal Therapies for Newly Diagnosed Elderly Patients with Glioblastoma.

Curr Treat Options Oncol 2017 10 27;18(11):66. Epub 2017 Oct 27.

Division of Neurology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.

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http://dx.doi.org/10.1007/s11864-017-0508-7DOI Listing
October 2017

Spinal intraoperative three-dimensional navigation: correlation between clinical and absolute engineering accuracy.

Spine J 2017 04 21;17(4):489-498. Epub 2016 Oct 21.

Division of Neurosurgery, Department of Surgery, University of Toronto, 399 Bathurst St., Toronto, ON, M5T 2S8, Canada; Institute of Medical Science, School of Graduate Studies, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada; Biophotonics and Bioengineering Laboratory, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada; Department of Electrical and Computer Engineering, Ryerson University, 350 Victoria St., Toronto, ON, M5B 2K3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.spinee.2016.10.020DOI Listing
April 2017

Understanding Hospital Volume-Outcome Relationship in Severe Traumatic Brain Injury.

Neurosurgery 2017 04;80(4):534-542

Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/neuros/nyw098DOI Listing
April 2017

Defining the Pathway to Definitive Care and Surgical Decompression after Traumatic Spinal Cord Injury: Results of a Canadian Population-Based Cohort Study.

J Neurotrauma 2016 05 11;33(10):963-71. Epub 2016 Feb 11.

1 Division of Neurosurgery and Spinal Program, University of Toronto , Toronto, Ontario, Canada .

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http://dx.doi.org/10.1089/neu.2015.4258DOI Listing
May 2016

Intracranial pressure monitoring among children with severe traumatic brain injury.

J Neurosurg Pediatr 2015 Nov 14;16(5):523-532. Epub 2015 Aug 14.

Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto.

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http://dx.doi.org/10.3171/2015.3.PEDS14507DOI Listing
November 2015

Dramatic Cataplexy Improvement Following Right Parietal Surgery.

J Clin Sleep Med 2015 Jul 15;11(7):829-30. Epub 2015 Jul 15.

Divison of Neurology, Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.5664/jcsm.4860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481063PMC
July 2015

Economic Evaluations in the Diagnosis and Management of Traumatic Brain Injury: A Systematic Review and Analysis of Quality.

Value Health 2015 Jul 26;18(5):721-34. Epub 2015 Jul 26.

Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada; Department of Surgery, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.jval.2015.04.012DOI Listing
July 2015

Economic evaluation of decompressive craniectomy versus barbiturate coma for refractory intracranial hypertension following traumatic brain injury.

Crit Care Med 2014 Oct;42(10):2235-43

1Sunnybrook Research Institute, Sunnybrook Health Sciences Center, Toronto, ON, Canada. 2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. 3Division of Neurosurgery, University of Ottawa, Ottawa, ON, Canada. 4Department of Medicine, University of Toronto, Toronto, ON, Canada. 5Division of Neurosurgery, University of Toronto, Toronto, ON, Canada. 6Department of Critical Care, Sunnybrook Health Sciences Center, Toronto, ON, Canada. 7Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada. 8Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada. 9Department of Surgery, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000000500DOI Listing
October 2014

Intracranial applications of magnetic resonance-guided focused ultrasound.

Neurotherapeutics 2014 Jul;11(3):593-605

Division of Neurosurgery, University Health Network, University of Toronto, 399 Bathurst Street, 4W-431, Toronoto, M5T 2S8, Canada,

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http://dx.doi.org/10.1007/s13311-014-0281-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121456PMC
July 2014

A systematic review of the effects of resident duty hour restrictions in surgery: impact on resident wellness, training, and patient outcomes.

Ann Surg 2014 Jun;259(6):1041-53

*Department of Surgery, University of Toronto, Toronto, Ontario, Canada †Department of Internal Medicine, Mount Sinai Hospital, New York City, NY ‡Department of Surgery, McGill University, Montreal, Quebec, Canada §Department of Internal Medicine, University of Toronto, Toronto, Ontario, Canada ‖Department of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada ¶Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada **Department of Surgery, Royal Inland Hospital, Kamloops, British Columbia, Canada.

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http://dx.doi.org/10.1097/SLA.0000000000000595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047317PMC
June 2014

A 49 year-old woman with a pineal mass.

Brain Pathol 2014 Mar;24(2):191-2

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http://dx.doi.org/10.1111/bpa.12121DOI Listing
March 2014

Tracheostomy timing in traumatic brain injury: a propensity-matched cohort study.

J Trauma Acute Care Surg 2014 Jan;76(1):70-6; discussion 76-8

From the Sunnybrook Research Institute (A.S.A., D.C.S., R.A.F., A.K., C.D.M., A.B.N.), Department of Critical Care (D.C.S., R.A.F.), Division of Neurosurgery (T.G.M.), Department of Research Design and Biostatistics (A.K.), and Department of Surgery (A.B.N.), Sunnybrook Health Sciences Center; Clinical Epidemiology Program (A.S.A., D.C.S., R.A.F., J.G.R., A.K., A.B.N.), Institute of Health Policy, Management and Evaluation, Interdepartmental Division of Critical Care (D.C.S., R.A.F.), and Keenan Research Centre of the Li Ka Shing Knowledge Institute (J.G.R, A.B.N) and Department of Medicine (J.G.R.), St. Michael's Hospital, University of Toronto, Toronto; and Division of Neurosurgery (A.S.A.), University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1097/TA.0b013e3182a8fd6aDOI Listing
January 2014

Probable IgG4-related pachymeningitis: a case with transverse sinus obliteration.

Clin Neuropathol 2013 Jul-Aug;32(4):291-7

Department of Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok.

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http://dx.doi.org/10.5414/NP300575DOI Listing
September 2013

Oligodendrogliomas with abundant refractile eosinophilic granular cells.

Can J Neurol Sci 2013 Sep;40(5):746-8

Department of Anatomical Pathology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1017/s0317167100015067DOI Listing
September 2013

Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound.

Nanomedicine 2012 Oct 17;8(7):1133-42. Epub 2012 Feb 17.

The Hospital for Sick Children - Arthur and Sonia Labatt Brain Tumour Research Centre, Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.nano.2012.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101537PMC
October 2012

Reducing time-to-treatment decreases mortality of trauma patients with acute subdural hematoma.

Ann Surg 2011 Jun;253(6):1178-83

Division of General Surgery, Tory Regional Trauma Centre, Sunnybrook Health Sciences Centre, University of Toronto, Canada.

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http://dx.doi.org/10.1097/SLA.0b013e318217e339DOI Listing
June 2011

An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma.

Cancer Res 2008 Dec;68(23):9945-53

Program in Cell Biology, Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, and Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2169DOI Listing
December 2008

Current concepts in the molecular genetics of pediatric brain tumors: implications for emerging therapies.

Childs Nerv Syst 2006 Nov 2;22(11):1379-94. Epub 2006 Sep 2.

Division of Neurosurgery, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada.

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http://link.springer.com/10.1007/s00381-006-0187-3
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http://dx.doi.org/10.1007/s00381-006-0187-3DOI Listing
November 2006

Endoscopic fenestration of a symptomatic cavum septum pellucidum: technical case report.

Neurosurgery 2006 Oct;59(4 Suppl 2):ONSE491; discussion ONSE491

Department of Neurosurgery, University Hospital Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1227/01.NEU.0000234051.86350.51DOI Listing
October 2006

A clinicobiological model predicting survival in medulloblastoma.

Clin Cancer Res 2004 Nov;10(22):7613-20

Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0499DOI Listing
November 2004

Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling.

Oncogene 2004 Jun;23(26):4577-83

The Division of Neurosurgery, The Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.1038/sj.onc.1207605DOI Listing
June 2004

Advanced cancer genetics in neurosurgical research.

Neurosurgery 2003 Nov;53(5):1168-78; discussion 1178

Division of Neurosurgery, Hospital for Sick Children, Arthur and Sonia Labatt Brain Tumor Research Center, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1227/01.neu.0000088807.95566.9bDOI Listing
November 2003

Imaging of murine brain tumors using a 1.5 Tesla clinical MRI system.

Can J Neurol Sci 2003 Nov;30(4):326-32

Arthur & Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1017/s0317167100003036DOI Listing
November 2003

Transcriptional profiling of medulloblastoma in children.

J Neurosurg 2003 Sep;99(3):534-41

Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3171/jns.2003.99.3.0534DOI Listing
September 2003

Bioinformatics in neurosurgery.

Neurosurgery 2003 Apr;52(4):723-30; discussion 730-1

Division of Neurosurgery, Hospital for Sick Children, Arthur and Sonia Labatt Brain Tumor Research Centre, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1227/01.neu.0000055042.61434.14DOI Listing
April 2003