Publications by authors named "Todd Heallen"

14Publications

Determinants of Cardiac Growth and Size.

Cold Spring Harb Perspect Biol 2020 03 2;12(3). Epub 2020 Mar 2.

Cardiomyocyte Renewal Lab, Texas Heart Institute, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/cshperspect.a037150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050588PMC
March 2020

Stimulating Cardiogenesis as a Treatment for Heart Failure.

Circ Res 2019 05;124(11):1647-1657

From the Cardiomyocyte Renewal Lab, Texas Heart Institute, Houston (T.R.H., J.H.K., J.F.M.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31357
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http://dx.doi.org/10.1161/CIRCRESAHA.118.313573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534162PMC
May 2019

Heart repair via cardiomyocyte-secreted vesicles.

Nat Biomed Eng 2018 05;2(5):271-272

Cardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41551-018-0239-5DOI Listing
May 2018

YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo.

Dev Cell 2019 03 14;48(6):765-779.e7. Epub 2019 Feb 14.

Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Cardiomyocyte Renewal Laboratory, Texas Heart Institute, 6770 Bertner Avenue, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Cardiovascular Research Institute, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807193004
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http://dx.doi.org/10.1016/j.devcel.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435425PMC
March 2019

The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration.

Nat Rev Cardiol 2018 11;15(11):672-684

Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41569-018-0063-3DOI Listing
November 2018

Hippo pathway deficiency reverses systolic heart failure after infarction.

Nature 2017 10 4;550(7675):260-264. Epub 2017 Oct 4.

Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature24045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729743PMC
October 2017

Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation.

Nature 2017 07 5;547(7662):227-231. Epub 2017 Jun 5.

Cardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature22979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528853PMC
July 2017

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.

Nature 2016 06 25;534(7605):119-23. Epub 2016 May 25.

Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature17959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999251PMC
June 2016

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice.

Sci Signal 2015 May 5;8(375):ra41. Epub 2015 May 5.

Texas Heart Institute, Houston, TX 77030, USA. Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA. Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1126/scisignal.2005781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442128PMC
May 2015

Hippo signaling impedes adult heart regeneration.

Development 2013 Dec;140(23):4683-90

Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1242/dev.102798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833428PMC
December 2013

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size.

Science 2011 Apr;332(6028):458-61

Institute of Biosciences and Technology, Texas A&M System Health Science Center, 2121 West Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1126/science.1199010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133743PMC
April 2011