Publications by authors named "Todd Druley"

49Publications

Germline Sequencing Identifies Rare Variants in Finnish Subjects with Familial Germ Cell Tumors.

Appl Clin Genet 2020 30;13:127-137. Epub 2020 Jun 30.

Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.2147/TACG.S245093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335280PMC
June 2020

Prevalence of clinically actionable disease variants in exceptionally long-lived families.

BMC Med Genomics 2020 04 10;13(1):61. Epub 2020 Apr 10.

Department of Laboratory Medicine and Pathology, University of Minnesota, MMC 609, 420 Delaware street, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1186/s12920-020-0710-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146901PMC
April 2020

The evolutionary dynamics and fitness landscape of clonal hematopoiesis.

Science 2020 03;367(6485):1449-1454

Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1126/science.aay9333DOI Listing
March 2020

Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring.

BMC Med Genomics 2020 03 4;13(1):32. Epub 2020 Mar 4.

Department of Pediatrics, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8116, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1186/s12920-020-0671-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057603PMC
March 2020

NF1 glioblastoma clonal profiling reveals mutations as potential somatic oncogenic events.

Neurology 2019 12 5;93(24):1067-1069. Epub 2019 Nov 5.

From the Division of Hematology and Oncology (W.H.W., T.E.D.), Department of Pediatrics, Washington University School of Medicine; Edison Family Center for Genome Sciences and Systems Biology (W.H.W., T.E.D.), Washington University School of Medicine, St. Louis, MO; Department of Neurology (L.J.), University of Michigan Health System, Ann Arbor; Department of Neurology (D.H.G.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000008623DOI Listing
December 2019

Novel mutation in AIRE gene with autoimmune polyendocrine syndrome type 1.

Immunobiology 2019 11 6;224(6):728-733. Epub 2019 Sep 6.

Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01712985193016
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http://dx.doi.org/10.1016/j.imbio.2019.09.004DOI Listing
November 2019

Scope of hearing loss in Beckwith-Wiedemann syndrome and hemihypertrophy.

Am J Med Genet A 2019 11 24;179(11):2307-2310. Epub 2019 Jul 24.

Washington University in Saint Louis School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1002/ajmg.a.61308DOI Listing
November 2019

Clonal hematopoiesis and risk of acute myeloid leukemia.

Haematologica 2019 12 19;104(12):2410-2417. Epub 2019 Apr 19.

Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, Saint Louis, MO

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http://dx.doi.org/10.3324/haematol.2018.215269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959179PMC
December 2019

Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites.

PLoS One 2018 26;13(9):e0203147. Epub 2018 Sep 26.

Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203147PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157835PMC
February 2019

Rare Event Detection Using Error-corrected DNA and RNA Sequencing.

J Vis Exp 2018 08 3(138). Epub 2018 Aug 3.

Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine; Center for Genome Sciences and Systems Biology, Washington University School of Medicine;

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http://dx.doi.org/10.3791/57509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126605PMC
August 2018

Parental Age and Risk of Infant Leukaemia: A Pooled Analysis.

Paediatr Perinat Epidemiol 2017 11 22;31(6):563-572. Epub 2017 Sep 22.

Division of Epidemiology & Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1111/ppe.12412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901723PMC
November 2017

Congenital neurodevelopmental anomalies in pediatric and young adult cancer.

Am J Med Genet A 2017 Oct 29;173(10):2670-2679. Epub 2017 Aug 29.

Division of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, Saint Louis, Missouri.

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http://dx.doi.org/10.1002/ajmg.a.38387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639360PMC
October 2017

Pediatric cancer risk in association with birth defects: A systematic review.

PLoS One 2017 27;12(7):e0181246. Epub 2017 Jul 27.

Department of Pediatrics, Washington University School of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181246PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716403PMC
September 2017

Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults.

Nat Commun 2016 08 22;7:12484. Epub 2016 Aug 22.

Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, Saint Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/ncomms12484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996934PMC
August 2016

Late toxicity of a novel allogeneic stem cell transplant using single fraction total body irradiation for hematologic malignancies in children.

J Pediatr Hematol Oncol 2015 Mar;37(2):e94-e101

Division of Pediatric Hematology-Oncology, Washington University School of Medicine, St Louis, MO.

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http://dx.doi.org/10.1097/MPH.0000000000000272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337424PMC
March 2015

Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection.

Nucleic Acids Res 2014 Jun 20;42(10):e82. Epub 2014 Mar 20.

Department of Orthopaedic Surgery, Washington University School of Medicine, 660 S Euclid Ave., St Louis, MO 63110, USA Department of Pediatrics, Washington University School of Medicine, 660 S Euclid Ave., St Louis, MO 63110, USA Department of Neurology, Washington University School of Medicine, 660 S Euclid Ave., St Louis, MO 63110, USA

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http://dx.doi.org/10.1093/nar/gku218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041413PMC
June 2014

Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome.

J Pediatr 2014 Jun 20;164(6):1316-21.e3. Epub 2014 Mar 20.

Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.

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https://linkinghub.elsevier.com/retrieve/pii/S00223476140014
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http://dx.doi.org/10.1016/j.jpeds.2014.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035386PMC
June 2014

Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.

Front Genet 2013 17;4:310. Epub 2014 Jan 17.

Sergievsky Center, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Taub Institute, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Department of Epidemiology, School of Public Health, Columbia University New York, NY, USA ; Department of Neurology, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Department of Psychiatry, College of Physicians and Surgeons, Columbia University New York, NY, USA.

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http://dx.doi.org/10.3389/fgene.2013.00310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567PMC
January 2014

Integrated analysis of germline and somatic variants in ovarian cancer.

Nat Commun 2014 ;5:3156

1] The Genome Institute, Washington University, St. Louis, Missouri 63108, USA [2] Department of Genetics, Washington University, St. Louis, Missouri 63108, USA [3] Siteman Cancer Center, Washington University, St. Louis, Missouri 63108, USA [4] Department of Medicine, Washington University, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/ncomms4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025965PMC
March 2016

Commentary.

Authors:
Todd E Druley

Clin Chem 2013 Jan;59(1):50-1

Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1373/clinchem.2012.192310DOI Listing
January 2013

Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome.

Pediatrics 2012 Dec 19;130(6):e1575-82. Epub 2012 Nov 19.

Division of Newborn Medicine, The Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110.

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http://dx.doi.org/10.1542/peds.2012-0918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507255PMC
December 2012

Detection of rare genomic variants from pooled sequencing using SPLINTER.

J Vis Exp 2012 Jun 23(64). Epub 2012 Jun 23.

Center for Genome Sciences and Systems Biology, Department of Genetics, Washington University School of Medicine.

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http://dx.doi.org/10.3791/3943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471313PMC
June 2012

High-throughput discovery of rare insertions and deletions in large cohorts.

Genome Res 2010 Dec 1;20(12):1711-8. Epub 2010 Nov 1.

Center for Genome Sciences and Systems Biology, Department of Genetics, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1101/gr.109157.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989997PMC
December 2010

Herbaspirillum species bacteremia in a pediatric oncology patient.

J Clin Microbiol 2010 Nov 25;48(11):4320-1. Epub 2010 Aug 25.

Departments of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1128/JCM.01479-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020882PMC
November 2010

Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.

J Clin Invest 2010 Jan 14;120(1):280-9. Epub 2009 Dec 14.

Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, 660 S. Eucliud Avenue, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1172/JCI39085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798680PMC
January 2010

Severe ceftriaxone-induced hemolysis complicated by diffuse cerebral ischemia in a child with sickle cell disease.

J Pediatr Hematol Oncol 2009 Nov;31(11):870-2

Division of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1097/MPH.0b013e3181b7eda2DOI Listing
November 2009