Tobias Schmid

Tobias Schmid

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Tobias Schmid

Publications by authors named "Tobias Schmid"

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The hypoxia-response pathway modulates RAS/MAPK-mediated cell fate decisions in .

Life Sci Alliance 2019 Jun 24;2(3). Epub 2019 May 24.

Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.26508/lsa.201800255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536719PMC
June 2019

Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation.

Cell Rep 2019 May;27(7):2022-2028.e3

Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt am Main 60590, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193053
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http://dx.doi.org/10.1016/j.celrep.2019.04.064DOI Listing
May 2019

Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype.

Nat Commun 2019 03 8;10(1):1135. Epub 2019 Mar 8.

Faculty of Medicine, Institute of Biochemistry I, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://dx.doi.org/10.1038/s41467-019-08989-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408494PMC
March 2019

Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia.

Cell Mol Life Sci 2018 08 20;75(16):3051-3067. Epub 2018 Feb 20.

Faculty of Medicine, Institute of Biochemistry I, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00018-018-2779-yDOI Listing
August 2018

Mapping the distribution of language related genes FoxP1, FoxP2, and CntnaP2 in the brains of vocal learning bat species.

J Comp Neurol 2018 06 28;526(8):1235-1266. Epub 2018 Feb 28.

Neurogenetics of Vocal Communication Group, Max Planck Institute for Psycholinguistics, Nijmegen, 6500 AH, The Netherlands.

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http://dx.doi.org/10.1002/cne.24385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900884PMC
June 2018

Inhibition of IRES-dependent translation of caspase-2 by HuR confers chemotherapeutic drug resistance in colon carcinoma cells.

Oncotarget 2018 Apr 6;9(26):18367-18385. Epub 2018 Apr 6.

Pharmazentrum Frankfurt/ZAFES, Medical School, Goethe-University Frankfurt, Frankfurt/Main, Germany.

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http://dx.doi.org/10.18632/oncotarget.24840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915078PMC
April 2018

Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.

Biochim Biophys Acta Gene Regul Mech 2018 Feb 31;1861(2):147-157. Epub 2018 Jan 31.

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2018.01.010DOI Listing
February 2018

The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors.

Mol Carcinog 2017 Dec 28;56(12):2620-2629. Epub 2017 Jul 28.

Medical Faculty, Institute of Biochemistry 1, Goethe-University Frankfurt, Frankfurt, Germany.

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http://doi.wiley.com/10.1002/mc.22706
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http://dx.doi.org/10.1002/mc.22706DOI Listing
December 2017

Ras/MAPK Modifier Loci Revealed by eQTL in .

G3 (Bethesda) 2017 09 7;7(9):3185-3193. Epub 2017 Sep 7.

Laboratory of Nematology, Wageningen University and Research, 6708PB, The Netherlands

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http://dx.doi.org/10.1534/g3.117.1120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592943PMC
September 2017

Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4.

PLoS One 2016 16;11(3):e0151643. Epub 2016 Mar 16.

Dipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur - Fondazione Cenci Bolognetti, "Sapienza" University of Rome, 00185, Rome, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151643PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794182PMC
July 2016

Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis.

J Pathol 2016 07 29;239(3):274-85. Epub 2016 Apr 29.

Institute of Biochemistry I, Goethe-University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1002/path.4724DOI Listing
July 2016

sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism.

Biochim Biophys Acta 2016 Jul 8;1859(7):848-59. Epub 2016 May 8.

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2016.05.005DOI Listing
July 2016

TNF and regulatory T cells are critical for sepsis-induced suppression of T cells.

Immun Inflamm Dis 2015 Dec 4;3(4):374-85. Epub 2015 Aug 4.

Institute of Immunology University of Regensburg Regensburg Germany.

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http://dx.doi.org/10.1002/iid3.75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693718PMC
December 2015

Tristetraprolin regulation of interleukin-22 production.

Sci Rep 2015 Oct 21;5:15112. Epub 2015 Oct 21.

pharmazentrum frankfurt/ZAFES, University Hospital Goethe-University Frankfurt, Germany.

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http://dx.doi.org/10.1038/srep15112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613560PMC
October 2015

Lymphotoxin α, a novel target of posttranscriptional gene regulation by HuR in HepG2 cells.

FEBS Lett 2015 Jul 14;589(15):1943-50. Epub 2015 May 14.

pharmazentrum frankfurt/ZAFES, Klinikum der Goethe-Universität Frankfurt, Frankfurt am Main, Germany. Electronic address:

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http://doi.wiley.com/10.1016/j.febslet.2015.05.015
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http://dx.doi.org/10.1016/j.febslet.2015.05.015DOI Listing
July 2015

Signal transduction during C. elegans vulval development: a NeverEnding story.

Curr Opin Genet Dev 2015 Jun 9;32:1-9. Epub 2015 Feb 9.

University of Zurich, Institute of Molecular Life Sciences, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2015.01.006DOI Listing
June 2015

Identification and characterisation of a prototype for a new class of competitive PPARγ antagonists.

Eur J Pharmacol 2015 May 5;755:16-26. Epub 2015 Mar 5.

Institute of Biochemistry I - Pathobiochemistry, Faculty of Medicine, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.02.034DOI Listing
May 2015

Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA.

PLoS Genet 2015 May 15;11(5):e1005236. Epub 2015 May 15.

University of Zurich, Institute of Molecular Life Sciences, Zurich, Switzerland.

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http://dx.doi.org/10.1371/journal.pgen.1005236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433219PMC
May 2015

The cytoskeletal inhibitors latrunculin A and blebbistatin exert antitumorigenic properties in human hepatocellular carcinoma cells by interfering with intracellular HuR trafficking.

Exp Cell Res 2015 Jan 21;330(1):66-80. Epub 2014 Sep 21.

Pharmazentrum Frankfurt/ZAFES, Klinikum der Goethe-Universität Frankfurt, Frankfurt/Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.09.010DOI Listing
January 2015

Inflammatory conditions induce IRES-dependent translation of cyp24a1.

PLoS One 2014 8;9(1):e85314. Epub 2014 Jan 8.

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085314PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885688PMC
September 2014

Tricyclic guanidine alkaloids from the marine sponge Acanthella cavernosa that stabilize the tumor suppressor PDCD4.

Mar Drugs 2014 Aug 21;12(8):4593-601. Epub 2014 Aug 21.

Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.3390/md12084593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145332PMC
August 2014

Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans.

Sci Rep 2014 May 13;4:4926. Epub 2014 May 13.

Laboratory of Nematology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.

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http://dx.doi.org/10.1038/srep04926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019968PMC
May 2014

IL-4 reduces the proangiogenic capacity of macrophages by down-regulating HIF-1α translation.

J Leukoc Biol 2014 Jan 4;95(1):129-37. Epub 2013 Sep 4.

1.Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1189/jlb.0113045DOI Listing
January 2014

Redox control of inflammation in macrophages.

Antioxid Redox Signal 2013 Aug 6;19(6):595-637. Epub 2013 Mar 6.

Faculty of Medicine, Institute of Biochemistry I-Pathobiochemistry, Goethe-University Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1089/ars.2012.4785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718318PMC
August 2013

Betulinic acid suppresses NGAL-induced epithelial-to-mesenchymal transition in melanoma.

Biol Chem 2013 Jun;394(6):773-81

Department of Pathophysiology, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.

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http://dx.doi.org/10.1515/hsz-2013-0106DOI Listing
June 2013

Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages.

Carcinogenesis 2013 Apr 14;34(4):850-7. Epub 2012 Dec 14.

Institute of Biochemistry I, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1093/carcin/bgs387DOI Listing
April 2013

IRES-dependent translation of egr2 is induced under inflammatory conditions.

RNA 2012 Oct 22;18(10):1910-20. Epub 2012 Aug 22.

Institute of Biochemistry I, Goethe-University Frankfurt, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1261/rna.033019.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446713PMC
October 2012

HIF-1α protein is upregulated in HIF-2α depleted cells via enhanced translation.

FEBS Lett 2012 Jun 2;586(11):1652-7. Epub 2012 May 2.

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.febslet.2012.04.039DOI Listing
June 2012

Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation.

Eur J Immunol 2012 May;42(5):1282-93

Department of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbrücken, Germany.

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http://dx.doi.org/10.1002/eji.201142081DOI Listing
May 2012

Observation of the Gouy phase anomaly in astigmatic beams.

Appl Opt 2012 May;51(15):2902-8

The Institute of Optics, University of Rochester, Rochester, New York 14627, USA.

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http://dx.doi.org/10.1364/AO.51.002902DOI Listing
May 2012

Suppression of hypoxia-inducible factor-1α contributes to the antiangiogenic activity of red propolis polyphenols in human endothelial cells.

J Nutr 2012 Mar 25;142(3):441-7. Epub 2012 Jan 25.

Department of Clinical and Toxicology Analysis, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil.

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http://dx.doi.org/10.3945/jn.111.150706DOI Listing
March 2012

Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4.

J Nat Prod 2011 May 3;74(5):1015-20. Epub 2011 May 3.

Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States.

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http://dx.doi.org/10.1021/np100918zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671369PMC
May 2011

Environment-assisted quantum transport and trapping in dimers.

Phys Rev E Stat Nonlin Soft Matter Phys 2010 Oct 21;82(4 Pt 1):042104. Epub 2010 Oct 21.

Physikalisches Institut, Universität Freiburg, Hermann-Herder-Straße 3, 79104 Freiburg, Germany.

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http://dx.doi.org/10.1103/PhysRevE.82.042104DOI Listing
October 2010

A combination of hypoxia and lipopolysaccharide activates tristetraprolin to destabilize proinflammatory mRNAs such as tumor necrosis factor-alpha.

Am J Pathol 2010 Sep 16;177(3):1104-12. Epub 2010 Jul 16.

Goethe-University Frankfurt, Faculty of Medicine, Institute of Biochemistry, Frankfurt, Germany.

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http://dx.doi.org/10.2353/ajpath.2010.091212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928945PMC
September 2010

Separation of the effects of astigmatic figure error from misalignments using Nodal Aberration Theory (NAT).

Opt Express 2010 Aug;18(16):17433-47

CREOL - The College of Optics and Photonics, University of Central Florida, Orlando, FL 32816, USA.

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http://dx.doi.org/10.1364/OE.18.017433DOI Listing
August 2010

Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.

Hepatology 2010 Jun;51(6):2183-92

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1002/hep.23597DOI Listing
June 2010

Misalignment-induced nodal aberration fields in two-mirror astronomical telescopes.

Appl Opt 2010 Jun;49(16):D131-44

CREOL, The College of Optics and Photonics, University of Central Florida, 4000 Central Florida Boulevard, Orlando, Florida 32816, USA.

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http://dx.doi.org/10.1364/AO.49.00D131DOI Listing
June 2010

MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization.

J Biol Chem 2010 Apr 17;285(16):11846-53. Epub 2010 Feb 17.

Institute of Biochemistry I/ZAFES, Faculty of Medicine, Goethe-University Frankfurt, Germany.

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http://dx.doi.org/10.1074/jbc.M109.066399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852921PMC
April 2010

Dissipative dynamics with trapping in dimers.

Phys Rev E Stat Nonlin Soft Matter Phys 2010 Apr 15;81(4 Pt 1):041114. Epub 2010 Apr 15.

Physikalisches Institut, Universität Freiburg, Hermann-Herder-Strasse 3, 79104 Freiburg, Germany.

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http://dx.doi.org/10.1103/PhysRevE.81.041114DOI Listing
April 2010

A unique astigmatic nodal property in misaligned Ritchey-Chrétien telescopes with misalignment coma removed.

Opt Express 2010 Mar;18(5):5282-8

CREOL - The College of Optics and Photonics, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816, USA.

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http://dx.doi.org/10.1364/OE.18.005282DOI Listing
March 2010

Real-ray-based method for locating individual surface aberration field centers in imaging optical systems without rotational symmetry.

J Opt Soc Am A Opt Image Sci Vis 2009 Jun;26(6):1503-17

Optical Research Associates, 3280 East Foothill Blvd., Suite 300, Pasadena, California 91107, USA.

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June 2009

The misalignment induced aberrations of TMA telescopes.

Opt Express 2008 Dec;16(25):20345-53

Optical Research Associates, 3280 E. Foothill Blvd, Suite 300, Pasadena, California 91107, USA.

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http://dx.doi.org/10.1364/oe.16.020345DOI Listing
December 2008

Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.

Cancer Res 2008 Mar 22;68(5):1254-60. Epub 2008 Feb 22.

Laboratory of Cancer Prevention, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1719DOI Listing
March 2008

Tumor hypoxia and cancer progression.

Cancer Lett 2006 Jun 5;237(1):10-21. Epub 2005 Jul 5.

Institute of Biochemistry I, Faculty of Medicine, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.canlet.2005.05.028DOI Listing
June 2006

Lights on for low oxygen: a noninvasive mouse model useful for sensing oxygen deficiency.

Mol Interv 2006 Feb;6(1):20-2, 2

Laboratory of Cancer Prevention, National Cancer Institute-Frederick, Maryland 21702, USA.

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http://mr.crossref.org/iPage?doi=10.1124%2Fmi.6.1.4
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http://dx.doi.org/10.1124/mi.6.1.4DOI Listing
February 2006

NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.

Free Radic Biol Med 2005 Oct;39(7):925-36

Institute of Biochemistry I, Faculty of Medicine, Johann Wolfgang Goethe-University, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2005.05.009DOI Listing
October 2005

HIF-1 and p53: communication of transcription factors under hypoxia.

J Cell Mol Med 2004 Oct-Dec;8(4):423-31

University of Kaiserslautern, Faculty of Biology, Department of Cell Biology, Kaiserslautern 67663, Germany.

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http://dx.doi.org/10.1111/j.1582-4934.2004.tb00467.xDOI Listing
January 2005

Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia.

FEBS Lett 2005 Jan;579(2):529-33

Department of Cell Biology, Faculty of Biology, University of Kaiserslautern, Erwin Schroedinger Strasse, 67663 Kaiserslautern, Germany.

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http://dx.doi.org/10.1016/j.febslet.2004.12.023DOI Listing
January 2005

HIF-1alpha and p53 as targets of NO in affecting cell proliferation, death and adaptation.

Curr Mol Med 2004 Nov;4(7):741-51

Department of Cell Biology, Faculty of Biology, University of Kaiserslautern, Kaiserslautern, Germany.

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November 2004

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

Biochem J 2004 May;380(Pt 1):289-95

Department of Cell Biology, Faculty of Biology, University of Kaiserslautern, Erwin Schroedinger Strasse 13/4, 67663 Kaiserslautern, Germany.

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http://dx.doi.org/10.1042/BJ20031299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224165PMC
May 2004

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

J Biol Chem 2004 Apr 15;279(14):13506-13. Epub 2004 Jan 15.

Department of Cell Biology, Faculty of Biology, University of Kaiserslautern, 67663 Kaiserslautern, Germany.

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http://dx.doi.org/10.1074/jbc.M310164200DOI Listing
April 2004

Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway.

Mol Biol Cell 2003 Jun 6;14(6):2216-25. Epub 2003 Feb 6.

Department of Cell Biology, Faculty of Biology, University of Kaiserslautern, 67663 Kaiserslautern, Germany.

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http://dx.doi.org/10.1091/mbc.e02-09-0598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC194872PMC
June 2003