Publications by authors named "Tobias Rausch"

46Publications

TRiCoLOR: tandem repeat profiling using whole-genome long-read sequencing data.

Gigascience 2020 Oct;9(10)

European Molecular Biology Laboratory (EMBL), GeneCore, Meyerhofstraße 1, Heidelberg 69117, Germany.

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http://dx.doi.org/10.1093/gigascience/giaa101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539535PMC
October 2020

Tracy: basecalling, alignment, assembly and deconvolution of sanger chromatogram trace files.

BMC Genomics 2020 Mar 14;21(1):230. Epub 2020 Mar 14.

European Molecular Biology Laboratory (EMBL), Genomics Core Facility, Heidelberg, 69117, Germany.

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http://dx.doi.org/10.1186/s12864-020-6635-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071639PMC
March 2020

A highly soluble Sleeping Beauty transposase improves control of gene insertion.

Nat Biotechnol 2019 12 4;37(12):1502-1512. Epub 2019 Nov 4.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41587-019-0291-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894935PMC
December 2019

VISOR: a versatile haplotype-aware structural variant simulator for short- and long-read sequencing.

Bioinformatics 2020 02;36(4):1267-1269

European Molecular Biology Laboratory (EMBL), GeneCore, Heidelberg 69917, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btz719DOI Listing
February 2020

The NSL complex maintains nuclear architecture stability via lamin A/C acetylation.

Nat Cell Biol 2019 10 1;21(10):1248-1260. Epub 2019 Oct 1.

Department of Chromatin Regulation, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41556-019-0397-zDOI Listing
October 2019

Multi-platform discovery of haplotype-resolved structural variation in human genomes.

Nat Commun 2019 04 16;10(1):1784. Epub 2019 Apr 16.

The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.

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http://www.nature.com/articles/s41467-018-08148-z
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http://dx.doi.org/10.1038/s41467-018-08148-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467913PMC
April 2019

Alfred: interactive multi-sample BAM alignment statistics, feature counting and feature annotation for long- and short-read sequencing.

Bioinformatics 2019 07;35(14):2489-2491

Genomics Core Facility, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bty1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612896PMC
July 2019

ToTem: a tool for variant calling pipeline optimization.

BMC Bioinformatics 2018 06 26;19(1):243. Epub 2018 Jun 26.

Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1186/s12859-018-2227-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020218PMC
June 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers.

BMC Cancer 2018 01 4;18(1):23. Epub 2018 Jan 4.

Department of Cell Biology, Laboratory of Signal Transduction, Nencki Institute of Experimental Biology of Polish Academy of Sciences, 3 Pasteur St, 02-093, Warsaw, Poland.

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
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http://dx.doi.org/10.1186/s12885-017-3943-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755140PMC
January 2018

Potential protective role of Grainyhead-like genes in the development of clear cell renal cell carcinoma.

Mol Carcinog 2017 Nov 15;56(11):2414-2423. Epub 2017 Jun 15.

Laboratory of Signal Transduction, Department of Cell Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.

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http://dx.doi.org/10.1002/mc.22682DOI Listing
November 2017

An integrated map of structural variation in 2,504 human genomes.

Nature 2015 Oct;526(7571):75-81

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature15394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617611PMC
October 2015

Identification of cytokine-induced modulation of microRNA expression and secretion as measured by a novel microRNA specific qPCR assay.

Sci Rep 2015 Jun 25;5:11590. Epub 2015 Jun 25.

Department of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, D 40225 Düsseldorf, Germany.

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http://www.nature.com/articles/srep11590
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http://dx.doi.org/10.1038/srep11590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480321PMC
June 2015

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Cancer Cell 2014 Mar;25(3):393-405

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69121 Heidelberg, Germany; Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ccr.2014.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493053PMC
March 2014

Identification of novel sequence variations in microRNAs in chronic lymphocytic leukemia.

Carcinogenesis 2014 May 4;35(5):992-1002. Epub 2013 Dec 4.

CEITEC - Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno 625 00, Czech Republic.

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http://dx.doi.org/10.1093/carcin/bgt396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004199PMC
May 2014

Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency.

J Allergy Clin Immunol 2013 May 3;131(5):1376-83.e3. Epub 2013 Apr 3.

Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jaci.2013.02.012DOI Listing
May 2013

Impact of genomic structural variation in Drosophila melanogaster based on population-scale sequencing.

Genome Res 2013 Mar 6;23(3):568-79. Epub 2012 Dec 6.

Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1101/gr.142646.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589545PMC
March 2013

DELLY: structural variant discovery by integrated paired-end and split-read analysis.

Bioinformatics 2012 Sep;28(18):i333-i339

European Molecular Biology Laboratory, Genome Biology, Meyerhofstr. 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bts378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436805PMC
September 2012

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

RazerS--fast read mapping with sensitivity control.

Genome Res 2009 Sep 10;19(9):1646-54. Epub 2009 Jul 10.

Department of Computer Science, Free University of Berlin, 14195 Berlin, Germany.

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http://dx.doi.org/10.1101/gr.088823.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752123PMC
September 2009

A consistency-based consensus algorithm for de novo and reference-guided sequence assembly of short reads.

Bioinformatics 2009 May 5;25(9):1118-24. Epub 2009 Mar 5.

International Max Planck Research School for Computational Biology and Scientific Computing, Ihnestr. 63-73, Algorithmische Bioinformatik, Institut für Informatik, Takustr. 9, 14195 Berlin, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btp131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732307PMC
May 2009

Segment-based multiple sequence alignment.

Bioinformatics 2008 Aug;24(16):i187-92

International Max Planck Research School for Computational Biology and Scientific Computing, Ihnestr 63-73, 14195 Berlin, Germany.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btn281DOI Listing
August 2008

A parallel genetic algorithm to discover patterns in genetic markers that indicate predisposition to multifactorial disease.

Comput Biol Med 2008 Jul 10;38(7):826-36. Epub 2008 Jun 10.

Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.compbiomed.2008.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532987PMC
July 2008

SeqAn an efficient, generic C++ library for sequence analysis.

BMC Bioinformatics 2008 Jan 9;9:11. Epub 2008 Jan 9.

Algorithmische Bioinformatik, Institut für Informatik, Takustr, 9, 14195 Berlin, Germany.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-9-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246154PMC
January 2008