Tobias Derfuss

Tobias Derfuss

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Tobias Derfuss

Publications by authors named "Tobias Derfuss"

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Advances in oral immunomodulating therapies in relapsing multiple sclerosis.

Lancet Neurol 2020 Feb 11. Epub 2020 Feb 11.

Neurology Clinic and Policlinic, Departments of Medicine, Clinical Research and Biomedicine University Hospital Basel, University of Basel, Basel, Switzerland; Department of Biomedical Engineering, University Hospital Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/S1474-4422(19)30391-6DOI Listing
February 2020

PARP-1 deregulation in multiple sclerosis.

Mult Scler J Exp Transl Clin 2019 Oct-Dec;5(4):2055217319894604. Epub 2019 Dec 16.

Departments of Biomedicine and Neurology, University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1177/2055217319894604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918498PMC
December 2019

A case of progressive multifocal leukoencephalopathy under dimethyl fumarate treatment without severe lymphopenia or immunosenescence.

Mult Scler 2019 10 18;25(12):1682-1685. Epub 2019 Jun 18.

Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1177/1352458519852100DOI Listing
October 2019

PML with dimethyl fumarate-No convincing case against natalizumab.

Mult Scler 2019 10 22;25(12):1687-1688. Epub 2019 Aug 22.

Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1177/1352458519872894DOI Listing
October 2019

Hepatitis E virus infections in patients with MS on oral disease-modifying treatment.

Neurol Neuroimmunol Neuroinflamm 2019 Sep 11;6(5). Epub 2019 Jul 11.

From the Departments of Medicine, University Hospital Basel, Neurologic Clinic and Policlinic, Clinical Research and Biomedicine, University of Basel, Petersgraben, Switzerland.

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http://dx.doi.org/10.1212/NXI.0000000000000594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705628PMC
September 2019

A case of concomitant psoriasis and multiple sclerosis: Secukinumab and rituximab exert dichotomous effects in two autoimmune conditions.

Mult Scler Relat Disord 2019 Jun 9;31:38-40. Epub 2019 Mar 9.

Neurological Clinic and Policlinic, University Hospital and University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.msard.2019.03.009DOI Listing
June 2019

Quantitative 7T MRI does not detect occult brain damage in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2019 May 7;6(3):e541. Epub 2019 Mar 7.

Neurologic Clinic and Policlinic (B.P., T.J.D., T.S.), Departments of Medicine, Clinical Research and Biomedical Engineering, University Hospital and University of Basel, Basel, Switzerland; NeuroCure Clinical Research Center (N.B., L.R., J.B.-S., F.P., T.S.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Department of Neurology (N.B., J.B.-S., K.R., F.P.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Experimental and Clinical Research Center (F.P.), Charité-Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine; Clinical and Experimental Multiple Sclerosis Research Center (K.R., F.P.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Berlin Ultrahigh Field Facility (T.N.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Germany; Medical Image Analysis Center AG (J.W., T.S.); and qbig (J.W.), Department of Biomedical Engineering, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1212/NXI.0000000000000541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410932PMC
May 2019

Central Slab versus Whole Brain to Measure Brain Atrophy in Multiple Sclerosis.

Eur Neurol 2018 3;80(3-4):207-214. Epub 2019 Jan 3.

Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research and Biomedical Engineering, University Hospital Basel and University of Basel, Basel, Switzerland,

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https://www.karger.com/Article/FullText/495798
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http://dx.doi.org/10.1159/000495798DOI Listing
March 2019

The monoclonal antibody GNbAC1: targeting human endogenous retroviruses in multiple sclerosis.

Ther Adv Neurol Disord 2019 7;12:1756286419833574. Epub 2019 Mar 7.

Neurological Policlinic and Clinic, University Hospital and University of Basel, Petersgraben 4, Basel, 4031, Switzerland.

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http://dx.doi.org/10.1177/1756286419833574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407165PMC
March 2019

Extensive bilateral brain lesions in neuromyelitis optica spectrum disorders.

Mult Scler 2018 08 20;24(9):1262-1263. Epub 2018 Apr 20.

Neurological Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1177/1352458518771888DOI Listing
August 2018

Anti-Myelin Oligodendrocyte Glycoprotein Antibody-Associated Central Nervous System Demyelination-A Novel Disease Entity?

JAMA Neurol 2018 08;75(8):909-910

Institute of Neuropathology, University Medical Center, Göttingen, Germany.

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http://dx.doi.org/10.1001/jamaneurol.2018.1055DOI Listing
August 2018

Serum neurofilament light chain: a biomarker of neuronal injury in vasculitic neuropathy.

Ann Rheum Dis 2018 07 25;77(7):1093-1094. Epub 2017 Jul 25.

Clinic for Rheumatology, Department of Medicine, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1136/annrheumdis-2017-212045DOI Listing
July 2018

Testosterone and estrogen in multiple sclerosis: from pathophysiology to therapeutics.

Expert Rev Neurother 2018 06 6;18(6):515-522. Epub 2018 Jun 6.

d Departments of Neurology and Biomedicine , University Hospital Basel , Basel , Switzerland.

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http://dx.doi.org/10.1080/14737175.2018.1481390DOI Listing
June 2018

Comparative analysis of natalizumab versus fingolimod as second-line treatment in relapsing-remitting multiple sclerosis.

Mult Scler 2018 05 24;24(6):777-785. Epub 2018 Apr 24.

Neurologic Clinic and Policlinic, Department of Neurology, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1177/1352458518768433DOI Listing
May 2018

Defining distinct features of anti-MOG antibody associated central nervous system demyelination.

Ther Adv Neurol Disord 2018 29;11:1756286418762083. Epub 2018 Mar 29.

Institute of Neuropathology, University Medical Center, Göttingen, Germany.

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http://dx.doi.org/10.1177/1756286418762083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881972PMC
March 2018

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.

Mult Scler 2018 02 20;24(2):96-120. Epub 2018 Jan 20.

Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunology (FZI), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1177/1352458517751049DOI Listing
February 2018

Dimethyl fumarate influences innate and adaptive immunity in multiple sclerosis.

J Autoimmun 2018 01 27;86:39-50. Epub 2017 Sep 27.

Laboratory of Clinical Neuroimmunology, Neurologic Clinic and Policlinic, Departments of Biomedicine and Clinical Research, University Hospital Basel and University of Basel, Hebelstrasse 20, 4031, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.09.009DOI Listing
January 2018

PML risk and natalizumab: the elephant in the room.

Lancet Neurol 2017 11 29;16(11):864-865. Epub 2017 Sep 29.

Neurology Clinic and Policlinic, Departments of Medicine, Biomedicine, Clinical Research, and Biomedical Engineering, University Hospital Basel, University of Basel, Basel 4031, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422173033
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http://dx.doi.org/10.1016/S1474-4422(17)30335-6DOI Listing
November 2017

Daclizumab for the treatment of multiple sclerosis.

Neurodegener Dis Manag 2017 Oct 29;7(5):279-297. Epub 2017 Aug 29.

Department of Neurology, University Hospital Basel & University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.2217/nmt-2017-0023DOI Listing
October 2017

α4-integrin receptor desaturation and disease activity return after natalizumab cessation.

Neurol Neuroimmunol Neuroinflamm 2017 Sep 25;4(5):e388. Epub 2017 Aug 25.

Neurological Clinic and Policlinic (T.D.), Departments of Medicine and Biomedicine, University Hospital Basel; Novartis Pharma AG (J.M.K., M.S., D.T.), Basel; Neurological Clinic and Policlinic (L.K.), Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel, Switzerland; Novartis Pharmaceuticals Corporation (Y.Z.), East Hanover, NJ; and Department of Neurology (H.W.), University of Münster, Germany; Novartis Healthcare Pvt. Ltd. (R.C.. A.T.), Hyderabad, India.

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http://dx.doi.org/10.1212/NXI.0000000000000388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572051PMC
September 2017

Expression of the Antioxidative Enzyme Peroxiredoxin 2 in Multiple Sclerosis Lesions in Relation to Inflammation.

Int J Mol Sci 2017 Apr 4;18(4). Epub 2017 Apr 4.

Institute of Neuropathology, University Hospital Essen, Hufelandstr. 55, Essen 45122, Germany.

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http://dx.doi.org/10.3390/ijms18040760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412345PMC
April 2017

Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop.

Mult Scler 2017 01 6:1352458516686847. Epub 2017 Jan 6.

Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1177/1352458516686847DOI Listing
January 2017

Interdisciplinary Risk Management in the Treatment of Multiple Sclerosis.

Dtsch Arztebl Int 2016 Dec;113(51-52):879-886

Institute for Clinical Neuroimmunology, Biomedical Center and Hospital, Ludwig-Maximilians Universität München, Munich; Department of Neurology, Faculty of Medicine, Heinrich Heine University Düsseldorf; Department of Neurology, University Hospital Basel; Munich Cluster for Systems Neurology (SyNergy).

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http://dx.doi.org/10.3238/arztebl.2016.0879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282476PMC
December 2016

Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity.

Mult Scler 2016 10 11;22(12):1550-1559. Epub 2016 Jan 11.

Advanced Clinical Imaging Technology Group, Siemens Healthcare IM BM PI, Lausanne, Switzerland/Neuro-Immunology, Neurology Division, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland/LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1177/1352458515623365DOI Listing
October 2016

Optimizing treatment success in multiple sclerosis.

J Neurol 2016 Jun 24;263(6):1053-65. Epub 2015 Dec 24.

Department of Neurology, Neuroimmunology and Multiple Sclerosis Research, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00415-015-7986-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893374PMC
June 2016

Natalizumab-induced POU2AF1/Spi-B upregulation: A possible route for PML development.

Neurol Neuroimmunol Neuroinflamm 2016 Jun 31;3(3):e223. Epub 2016 Mar 31.

Clinical Neuroimmunology (M.M., C.S., F.H., M.R., B.F.D., J.K., T.D., L.K., R.L.P.L.), Departments of Biomedicine and Neurology, University Hospital Basel, Switzerland; and Department of Neurology (A.H.), St. Josef-Hospital, Ruhr-University Bochum, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821666PMC
June 2016

Disease activity return after natalizumab cessation in multiple sclerosis.

Expert Rev Neurother 2016 05 6;16(5):587-94. Epub 2016 Apr 6.

a Department of Neurology , University Hospital Basel , Basel , Switzerland.

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http://dx.doi.org/10.1586/14737175.2016.1168295DOI Listing
May 2016

Severe exacerbation of relapsing-remitting multiple sclerosis after G-CSF therapy.

Neurol Neuroimmunol Neuroinflamm 2016 Apr 9;3(2):e215. Epub 2016 Mar 9.

University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1212/NXI.0000000000000215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794809PMC
April 2016

Multiple Sclerosis and Antibodies against KIR4.1.

N Engl J Med 2016 Apr;374(15):1496-8

University Hospital Basel, Basel, Switzerland

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http://dx.doi.org/10.1056/NEJMc1507131DOI Listing
April 2016

Promising Oral Compounds for the Treatment of Multiple Sclerosis: A Glance into the Future.

Semin Neurol 2016 Apr 26;36(2):128-39. Epub 2016 Apr 26.

Department of Neurology, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1055/s-0036-1580720DOI Listing
April 2016

Immunological treatment of multiple sclerosis.

Semin Hematol 2016 04 7;53 Suppl 1:S54-7. Epub 2016 Apr 7.

Departments of Neurology and Biomedicine, University Hospital Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2016.04.016DOI Listing
April 2016

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.

J Neuroinflammation 2015 Dec 18;12:235. Epub 2015 Dec 18.

Institute of Clinical Neuroimmunology, Biomedical Center (BMC) and University Hospital, Campus Martinsried-Grosshadern, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1186/s12974-015-0450-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683913PMC
December 2015

Immunologic monitoring during a phase 2a trial of the GNbAC1 antibody in patients with MS.

Neurol Neuroimmunol Neuroinflamm 2015 Oct 20;2(5):e144. Epub 2015 Aug 20.

Laboratory of Clinical Neuroimmunology (M.Z., N.S.R.S., M.R., R.L.P.L., L.K., T.D.), Department of Biomedicine, University Hospital Basel and University of Basel, Switzerland; Department of Neurology (M.R., L.K., T.D.), University Hospital Basel, Switzerland; Department of Neurosciences (P.H.L.), Division of Neurology, University Hospital Geneva and Faculty of Medicine, Geneva, Switzerland; and GeNeuro SA (A.B.L., F.C.), Plan-les-Ouates/Geneva, Switzerland.

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http://dx.doi.org/10.1212/NXI.0000000000000144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547879PMC
October 2015

Optimizing treatment initiation: Effects of a patient education program about fingolimod treatment on knowledge, self-efficacy and patient satisfaction.

Mult Scler Relat Disord 2015 Sep 19;4(5):444-450. Epub 2015 Jun 19.

Departments of Neurology and Biomedicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2015.06.010DOI Listing
September 2015

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up.

J Neuroimmunol 2015 Aug 20;285:68-70. Epub 2015 May 20.

Department of Clinical Neurosciences, Division of Neurology, Unit of Neuroimmunology and Multiple Sclerosis, Geneva University Hospital, 1211 Geneva, Switzerland; Department of Genetic and Laboratory Medicine, Division of Laboratory Medicine, Geneva University Hospital, 1211 Geneva, Switzerland; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.jneuroim.2015.05.019DOI Listing
August 2015

Switching from natalizumab to fingolimod: A randomized, placebo-controlled study in RRMS.

Neurology 2015 Jul 29;85(1):29-39. Epub 2015 May 29.

From Neurology, the Departments of Medicine, Clinical Research and Biomedicine (L.K., T.D., Y.N., T.S.), the Medical Image Analysis Center (MIAC) (E.-W.R., T.S., N.M.-L.), and the Department of Radiology, Division of Neuroradiology (T.S.), University Hospital, University of Basel, Switzerland; the Department of Neuroscience (G.C.), Scientific Institute H. San Raffaele, University of Milan, Italy; Vall d'Hebron University Hospital (X.M.), Barcelona, Spain; Royal Melbourne Hospital (H.B.), Parkville, Australia; the Department of Neurology (H.W.), University of Münster, Germany; the Neuroscience and Trauma Centre (G.G.), Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK; the Department of Neurology (H.-P.H.), Heinrich Heine University, Düsseldorf, Germany; Oxford PharmaGenesis Ltd. (S.G.), Tubney Warren Barns, Oxford, UK; Novartis Pharma AG (P.v.R., Y.Z., F.D., D.T.), Basel, Switzerland; and Novartis Pharmaceutical Corporation (R.G.), East Hanover, NJ.

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http://www.neurology.org/content/85/1/29.full.pdf
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000170
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http://dx.doi.org/10.1212/WNL.0000000000001706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501941PMC
July 2015

B Cells and Autoantibodies in Multiple Sclerosis.

Int J Mol Sci 2015 Jul 21;16(7):16576-92. Epub 2015 Jul 21.

Department of Neurology, University Hospital Basel, Petersgraben 4 & Clinical Neuroimmunology, Hebelstrasse 20, 4031 Basel, Switzerland.

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http://dx.doi.org/10.3390/ijms160716576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519967PMC
July 2015

A pragmatic approach to dealing with fingolimod-related lymphopaenia in Europe.

Mult Scler Relat Disord 2015 Jan 13;4(1):83-4. Epub 2014 Oct 13.

Department of Laboratory Medicine, Stem Cell Center, Lund University, Sweden; Department of Hematology, Skåne University Hospital, Sweden.

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http://dx.doi.org/10.1016/j.msard.2014.09.215DOI Listing
January 2015

Unraveling natalizumab effects on deregulated miR-17 expression in CD4+ T cells of patients with relapsing-remitting multiple sclerosis.

J Immunol Res 2014 12;2014:897249. Epub 2014 May 12.

Clinical Neuroimmunology, Departments of Biomedicine and Neurology, University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland.

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http://dx.doi.org/10.1155/2014/897249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036714PMC
December 2014

Cerebellar abnormalities contribute to disability including cognitive impairment in multiple sclerosis.

PLoS One 2014 22;9(1):e86916. Epub 2014 Jan 22.

Department of Neurology, University Hospital Basel, Basel, Switzerland ; Department of Radiology, Division of Neuroradiology, University Hospital Basel, Basel, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086916PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899307PMC
September 2014

MiR-126: a novel route for natalizumab action?

Mult Scler 2014 Sep 5;20(10):1363-70. Epub 2014 Mar 5.

University Hospital Basel, University of Basel, Switzerland

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http://dx.doi.org/10.1177/1352458514524998DOI Listing
September 2014

Predicting PML in natalizumab-treated patients: can we do better?

J Neurol Neurosurg Psychiatry 2013 Nov 20;84(11):1182-3. Epub 2013 Apr 20.

Department of Neurology, University Hospital Basel, , Basel, Switzerland.

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http://dx.doi.org/10.1136/jnnp-2012-304777DOI Listing
November 2013

T-cell response against varicella-zoster virus in fingolimod-treated MS patients.

Neurology 2013 Jul 22;81(2):174-81. Epub 2013 May 22.

Clinical Neuroimmunology, Department of Biomedicine, University of Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0b013e31829a3311DOI Listing
July 2013

Natalizumab therapy for multiple sclerosis.

Semin Neurol 2013 Feb 25;33(1):26-36. Epub 2013 May 25.

Department of Neurology, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1055/s-0033-1343793DOI Listing
February 2013

B cells and antibodies in multiple sclerosis pathogenesis and therapy.

Nat Rev Neurol 2012 Nov 9;8(11):613-23. Epub 2012 Oct 9.

Institute of Clinical Neuroimmunology, Ludwig Maximilian University Munich, Germany.

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http://dx.doi.org/10.1038/nrneurol.2012.203DOI Listing
November 2012

Personalized medicine in multiple sclerosis: hope or reality?

Authors:
Tobias Derfuss

BMC Med 2012 Oct 4;10:116. Epub 2012 Oct 4.

Department of Neurology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

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http://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7
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http://dx.doi.org/10.1186/1741-7015-10-116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523020PMC
October 2012

Identifying autoantigens in demyelinating diseases: valuable clues to diagnosis and treatment?

Curr Opin Neurol 2012 Jun;25(3):231-8

Clinical Neuroimmunology, Department of Biomedicine, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1097/WCO.0b013e3283533a64DOI Listing
June 2012

Clonal expansions of CD8⁺ T cells in latently HSV-1-infected human trigeminal ganglia.

J Neurovirol 2012 Feb 14;18(1):62-8. Epub 2011 Dec 14.

Institute of Clinical Neuroimmunology, Ludwig Maximilian University, 81377 Munich, Germany.

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http://dx.doi.org/10.1007/s13365-011-0067-9DOI Listing
February 2012

Control of HSV-1 latency in human trigeminal ganglia--current overview.

J Neurovirol 2011 Dec 3;17(6):518-27. Epub 2011 Dec 3.

Institute of Neuroimmunology, Max-Planck-Institute of Neurobiology, 82152, Martinsried, Germany.

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http://link.springer.com/10.1007/s13365-011-0063-0
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http://dx.doi.org/10.1007/s13365-011-0063-0DOI Listing
December 2011

Fingolimod for multiple sclerosis: mechanism of action, clinical outcomes, and future directions.

Curr Neurol Neurosci Rep 2011 Oct;11(5):492-7

Department of Neurology and Department of Biomedicine, University Hospital Basel, Petersgraben, Switzerland.

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http://dx.doi.org/10.1007/s11910-011-0216-9DOI Listing
October 2011

Humoral autoimmunity in multiple sclerosis.

J Neurol Sci 2011 Jul 3;306(1-2):180-2. Epub 2010 Sep 3.

Department of Neuroimmunology, Max Planck Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X100035
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http://dx.doi.org/10.1016/j.jns.2010.08.009DOI Listing
July 2011

Non-paraneoplastic limbic encephalitis associated with NMDAR and VGKC antibodies.

J Neurol Neurosurg Psychiatry 2010 Dec 28;81(12):1407-8. Epub 2010 Jul 28.

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http://dx.doi.org/10.1136/jnnp.2009.186494DOI Listing
December 2010

Axo-glial antigens as targets in multiple sclerosis: implications for axonal and grey matter injury.

J Mol Med (Berl) 2010 Aug 6;88(8):753-61. Epub 2010 May 6.

Department of Neurology, Friedrich-Alexander-University, Schwabachanlage 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00109-010-0632-3DOI Listing
August 2010

The presence of lytic HSV-1 transcripts and clonally expanded T cells with a memory effector phenotype in human sensory ganglia.

Ann N Y Acad Sci 2009 May;1164:300-4

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1111/j.1749-6632.2009.03871.xDOI Listing
May 2009

Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis.

J Neuroimmunol 2008 Nov;204(1-2):92-100

Department of Pathology, University of Utah School of Medicine, 30 North 1900 East, RM 3R330, Salt Lake City, Utah 84132, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2008.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646907PMC
November 2008

Compartmentalization of inflammation in the CNS: a major mechanism driving progressive multiple sclerosis.

J Neurol Sci 2008 Nov 19;274(1-2):42-4. Epub 2008 Aug 19.

Department of Neuroimmunology, Max Planck Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1016/j.jns.2008.06.032DOI Listing
November 2008

The prevalence of human herpesvirus 6 in human sensory ganglia and its co-occurrence with alpha-herpesviruses.

J Neurovirol 2007 Oct;13(5):462-7

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistrasse 23, Munich, Germany.

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http://dx.doi.org/10.1080/13550280701447059DOI Listing
October 2007

Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response.

J Neurol 2005 Aug 21;252(8):968-71. Epub 2005 Mar 21.

Dept. of Neuroimmunology, Max-Planck-Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany.

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http://link.springer.com/10.1007/s00415-005-0794-z
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http://dx.doi.org/10.1007/s00415-005-0794-zDOI Listing
August 2005

Expression and function of glial cell line-derived neurotrophic factor family ligands and their receptors on human immune cells.

J Immunol 2005 Aug;175(4):2301-8

Department of Neuroimmunology, Max-Planck-Institute of Neurobiology, Martinsried, Germany.

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http://dx.doi.org/10.4049/jimmunol.175.4.2301DOI Listing
August 2005

Prevalence and distribution of HSV-1, VZV, and HHV-6 in human cranial nerve nuclei III, IV, VI, VII, and XII.

J Med Virol 2004 Sep;74(1):102-6

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1002/jmv.20152DOI Listing
September 2004

Dually infected (HSV-1/VZV) single neurons in human trigeminal ganglia.

Ann Neurol 2003 Nov;54(5):678-82

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistrasse 23, 81377 Munich, Germany.

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http://dx.doi.org/10.1002/ana.10746DOI Listing
November 2003