Publications by authors named "Tobias Boettler"

51Publications

IL-2 contributes to cirrhosis-associated immune dysfunction by impairing follicular T helper cells in advanced cirrhosis.

J Hepatol 2020 Oct 24. Epub 2020 Oct 24.

Department of Medicine II, Medical Center - University of Freiburg, Germany; Faculty of Medicine, University of Freiburg, Germany; Berta-Ottenstein-Programme, Faculty of Medicine, University of Freiburg, Germany. Electronic address:

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October 2020

Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper.

JHEP Rep 2020 Jun 2;2(3):100113. Epub 2020 Apr 2.

Division of Hepatology, Clinic and Polyclinic for Gastroenterology, Hepatology, Infectious Diseases, and Pneumology, University Hospital Leipzig, Leipzig, Germany.

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June 2020

Exhausted phenotype of follicular CD8 T cells in CVID.

J Allergy Clin Immunol 2020 Oct 10;146(4):912-915.e13. Epub 2020 Mar 10.

Divison of Immunodeficiency, Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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October 2020

Efficacy of Retreatment After Failed Direct-acting Antiviral Therapy in Patients With HCV Genotype 1-3 Infections.

Clin Gastroenterol Hepatol 2021 Jan 6;19(1):195-198.e2. Epub 2019 Nov 6.

Department of Internal Medicine 1, University Hospital Frankfurt, Goethe University, Frankfurt, and German Center for Infection Research (DZIF), External Partner Site, Frankfurt, Germany; Medizinische Klinik 2, St Josefs-Hospital, Wiesbaden, Germany. Electronic address:

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January 2021

Acute pancreatitis and vasoplegic shock associated with leptospirosis - a case report and review of the literature.

BMC Infect Dis 2019 May 8;19(1):395. Epub 2019 May 8.

Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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May 2019

HCV-Specific T Cell Responses During and After Chronic HCV Infection.

Viruses 2018 11 17;10(11). Epub 2018 Nov 17.

Department of Medicine II, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

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November 2018

Treatment with proton pump inhibitors increases the risk for development of hepatic encephalopathy after implantation of transjugular intrahepatic portosystemic shunt (TIPS).

United European Gastroenterol J 2018 Nov 15;6(9):1380-1390. Epub 2018 Aug 15.

Department of Medicine II, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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November 2018

Follicular T Helper Cell Signatures in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.

Hepatol Commun 2018 Sep 7;2(9):1051-1063. Epub 2018 Sep 7.

Department of Medicine II, University Medical Cewnter, Faculty of Medicine University of Freiburg Freiburg Germany.

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September 2018

Lost in Inflammation: The Functional Conversion of Regulatory T Cells in Acute Hepatitis A Virus Infection.

Gastroenterology 2018 03 7;154(4):798-800. Epub 2018 Feb 7.

Department of Medicine II, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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March 2018

Differential virus-specific CD8 T-cell epitope repertoire in hepatitis C virus genotype 1 versus 4.

J Viral Hepat 2018 07 27;25(7):779-790. Epub 2018 Feb 27.

Faculty of Medicine, Department of Medicine II, University Hospital Freiburg, University of Freiburg, Freiburg, Germany.

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July 2018

Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience.

BMC Gastroenterol 2017 Aug 10;17(1):98. Epub 2017 Aug 10.

Department of Medicine II, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, D-79106, Freiburg, Germany.

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August 2017

[Cholestatic liver disease].

Dtsch Med Wochenschr 2016 Nov 17;141(23):1683-1687. Epub 2016 Nov 17.

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November 2016

A rare cause of upper GI bleeding in a critically ill patient.

Gut 2016 09 30;65(9):1438. Epub 2015 Dec 30.

Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.

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September 2016

[Cure of chronic Hepatitis B and C: vision versus reality].

Dtsch Med Wochenschr 2015 Jul 16;140(14):1056-62. Epub 2015 Jul 16.

Klinik für Innere Medizin II, Gastroenterologie, Hepatologie, Endokrinologie und Infektiologie, Universitätsklinikum Freiburg.

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July 2015

Antiviral Therapy in Hepatitis B Virus-Associated Liver Cirrhosis.

Dig Dis 2015 6;33(4):608-12. Epub 2015 Jul 6.

Clinic for Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Freiburg, Freiburg, Germany.

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April 2016

An uncommon presentation of a common pathogen.

Gut 2015 Sep 6;64(9):1411, 1453. Epub 2015 Jan 6.

Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.

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September 2015

Bridging basic science and clinical research: the EASL Monothematic Conference on Translational Research in Viral Hepatitis.

J Hepatol 2014 Sep 15;61(3):696-705. Epub 2014 May 15.

INSERM U1052, Cancer Research Center of Lyon (CRCL), Hepatology Department, Hospices Civils de Lyon, France. Electronic address:

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September 2014

The clinical and immunological significance of GAD-specific autoantibody and T-cell responses in type 1 diabetes.

J Autoimmun 2013 Aug 13;44:40-8. Epub 2013 Jun 13.

Type 1 Diabetes Center, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.

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August 2013

OX40 facilitates control of a persistent virus infection.

PLoS Pathog 2012 Sep 6;8(9):e1002913. Epub 2012 Sep 6.

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.

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September 2012

IL-7 receptor α blockade, an off-switch for autoreactive T cells.

Proc Natl Acad Sci U S A 2012 Jul 23;109(31):12270-1. Epub 2012 Jul 23.

Department of Internal Medicine II, University Hospital Freiburg, 79106 Freiburg, Germany.

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July 2012

TGF-β blockade does not improve control of an established persistent viral infection.

Viral Immunol 2012 Jun 23;25(3):232-8. Epub 2012 May 23.

La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.

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June 2012

Can an immune-regulatory vaccine prevent HIV infection?

Expert Rev Anti Infect Ther 2012 Mar;10(3):299-305

Division of Developmental Immunology at the La Jolla Institute for Allergy & Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA.

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March 2012

Virus infections in type 1 diabetes.

Cold Spring Harb Perspect Med 2012 Jan;2(1):a007682

Center for Type 1 Diabetes Research, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

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January 2012

Protection against or triggering of Type 1 diabetes? Different roles for viral infections.

Expert Rev Clin Immunol 2011 Jan;7(1):45-53

La Jolla Institute for Allergy and Immunology - LIAI, 9420 Athena Circle, La Jolla, CA 92037, USA.

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January 2011

Type 1 diabetes vaccine development: animal models vs. humans.

Hum Vaccin 2011 Jan 1;7(1):19-26. Epub 2011 Jan 1.

La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.

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January 2011

Immunotherapy of type 1 diabetes--how to rationally prioritize combination therapies in T1D.

Int Immunopharmacol 2010 Dec 25;10(12):1491-5. Epub 2010 Jul 25.

La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.

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December 2010

Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine.

Biol Chem 2008 May;389(5):457-67

Department of Medicine II, University Hospital Freiburg, D-79106 Freiburg, Germany.

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May 2008