Tobey J MacDonald

Tobey J MacDonald

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Tobey J MacDonald

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Host Genome Variation is Associated with Neurocognitive Outcome in Survivors of Pediatric Medulloblastoma.

Transl Oncol 2019 Jul 9;12(7):908-916. Epub 2019 May 9.

Department of Pediatrics, Emory University School of Medicine, Atlanta, GA; Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1016/j.tranon.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515414PMC
July 2019

Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma.

Nat Commun 2019 06 3;10(1):2410. Epub 2019 Jun 3.

Department of Pediatrics, Neuro-Oncology Division and Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Emory University, Atlanta, 30322, GA, United States.

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http://dx.doi.org/10.1038/s41467-019-10458-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546707PMC
June 2019

Three-Dimensional Mass Spectrometry Imaging Identifies Lipid Markers of Medulloblastoma Metastasis.

Sci Rep 2019 Feb 18;9(1):2205. Epub 2019 Feb 18.

Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1038/s41598-018-38257-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379434PMC
February 2019

White matter network topology relates to cognitive flexibility and cumulative neurological risk in adult survivors of pediatric brain tumors.

Neuroimage Clin 2018 10;20:485-497. Epub 2018 Aug 10.

Department of Psychology, Georgia State University, Atlanta, GA, United States; Neuroscience Institute, Georgia State University, Atlanta, GA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105768PMC
January 2019

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

Phase I study of oral sonidegib (LDE225) in pediatric brain and solid tumors and a phase II study in children and adults with relapsed medulloblastoma.

Neuro Oncol 2017 Oct;19(11):1542-1552

Pediatric Neuro-Oncology, Dana-Farber Boston Children's Cancer Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, USA; The Royal Marsden Hospital, Sutton, Surrey, UK; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Medical Oncology, Azienda USL-IRCCS Institute of Neurological Science, Bologna, Italy; Institut Curie and University Paris Descartes, Paris, France; Division of Haematology/Oncology at The Hospital for Sick Children, Toronto, Ontario, Canada; Sir James Spence Institute of Child Health Royal Victoria Infirmary, Newcastle, UK; Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, Washington, USA; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA; The Royal Children's Hospital, Children's Cancer Center, Melbourne, Australia; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA; Catholic University of the Sacred Heart, Rome, Italy; Cancer Clinical Research Unit, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Paediatric Oncology Unit, Great Ormond Street Hospital, London, UK; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA; Gustave Roussy, Department of Pediatric and Adolescent Oncology, University Paris-Sud, Université Paris-Saclay, Villejuif, France.

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http://dx.doi.org/10.1093/neuonc/nox109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737275PMC
October 2017

Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma.

Neuro Oncol 2016 06 19;18(6):881-7. Epub 2015 Dec 19.

Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia (B.R.E., N.E.); Pediatrics, Emory University School of Medicine and Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Atlanta, Georgia (B.P., C.M., T.J.M.); Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, California (S.K.); Pediatrics, Massachusetts General Hospital, Boston, Massachusetts (D.E.); Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (B.R.E., E.A.W., L.T.T., S.M.M., N.J.T., T.I.Y.).

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http://dx.doi.org/10.1093/neuonc/nov302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864263PMC
June 2016

Hedgehog Pathway in Pediatric Cancers: They're Not Just for Brain Tumors Anymore.

Am Soc Clin Oncol Educ Book 2012 :605-9

From the Pediatric Neuro-Oncology Program, Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta, and Emory University School of Medicine, Emory Children's Center, Atlanta, GA.

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http://dx.doi.org/10.14694/EdBook_AM.2012.32.605DOI Listing
April 2016

Successful Retreatment of a Child with a Refractory Brainstem Ganglioglioma with Vemurafenib.

Pediatr Blood Cancer 2016 Mar 18;63(3):541-3. Epub 2015 Nov 18.

Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1002/pbc.25787DOI Listing
March 2016

Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:
A Sorana Morrissy Livia Garzia David J H Shih Scott Zuyderduyn Xi Huang Patryk Skowron Marc Remke Florence M G Cavalli Vijay Ramaswamy Patricia E Lindsay Salomeh Jelveh Laura K Donovan Xin Wang Betty Luu Kory Zayne Yisu Li Chelsea Mayoh Nina Thiessen Eloi Mercier Karen L Mungall Yusanne Ma Kane Tse Thomas Zeng Karey Shumansky Andrew J L Roth Sohrab Shah Hamza Farooq Noriyuki Kijima Borja L Holgado John J Y Lee Stuart Matan-Lithwick Jessica Liu Stephen C Mack Alex Manno K A Michealraj Carolina Nor John Peacock Lei Qin Juri Reimand Adi Rolider Yuan Y Thompson Xiaochong Wu Trevor Pugh Adrian Ally Mikhail Bilenky Yaron S N Butterfield Rebecca Carlsen Young Cheng Eric Chuah Richard D Corbett Noreen Dhalla An He Darlene Lee Haiyan I Li William Long Michael Mayo Patrick Plettner Jenny Q Qian Jacqueline E Schein Angela Tam Tina Wong Inanc Birol Yongjun Zhao Claudia C Faria José Pimentel Sofia Nunes Tarek Shalaby Michael Grotzer Ian F Pollack Ronald L Hamilton Xiao-Nan Li Anne E Bendel Daniel W Fults Andrew W Walter Toshihiro Kumabe Teiji Tominaga V Peter Collins Yoon-Jae Cho Caitlin Hoffman David Lyden Jeffrey H Wisoff James H Garvin Duncan S Stearns Luca Massimi Ulrich Schüller Jaroslav Sterba Karel Zitterbart Stephanie Puget Olivier Ayrault Sandra E Dunn Daniela P C Tirapelli Carlos G Carlotti Helen Wheeler Andrew R Hallahan Wendy Ingram Tobey J MacDonald Jeffrey J Olson Erwin G Van Meir Ji-Yeoun Lee Kyu-Chang Wang Seung-Ki Kim Byung-Kyu Cho Torsten Pietsch Gudrun Fleischhack Stephan Tippelt Young Shin Ra Simon Bailey Janet C Lindsey Steven C Clifford Charles G Eberhart Michael K Cooper Roger J Packer Maura Massimino Maria Luisa Garre Ute Bartels Uri Tabori Cynthia E Hawkins Peter Dirks Eric Bouffet James T Rutka Robert J Wechsler-Reya William A Weiss Lara S Collier Adam J Dupuy Andrey Korshunov David T W Jones Marcel Kool Paul A Northcott Stefan M Pfister David A Largaespada Andrew J Mungall Richard A Moore Nada Jabado Gary D Bader Steven J M Jones David Malkin Marco A Marra Michael D Taylor

Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.

Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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http://dx.doi.org/10.1038/nature16478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936195PMC
January 2016

EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma.

J Neurooncol 2015 Jan 26;121(1):109-18. Epub 2014 Sep 26.

Department of Pediatrics, Emory Children's Center, Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, 2015 Uppergate Drive NE, 4th Floor, Atlanta, GA, 30322, USA.

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http://link.springer.com/content/pdf/10.1007/s11060-014-1618
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http://link.springer.com/10.1007/s11060-014-1618-8
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http://dx.doi.org/10.1007/s11060-014-1618-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293301PMC
January 2015

Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283.

Cancer Lett 2014 Nov 10;354(1):68-76. Epub 2014 Aug 10.

Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, 1760 Haygood Drive, HSRB E-384, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.07.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179499PMC
November 2014

Response of subependymal giant cell astrocytoma with spinal cord metastasis to everolimus.

J Pediatr Hematol Oncol 2014 Oct;36(7):e448-51

*Aflac Cancer and Blood Disorders Center ‡Department of Pathology, Children's Healthcare of Atlanta, Emory University School of Medicine Departments of †Neurology §Radiology ∥Neurosurgery, Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1097/MPH.0000000000000005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009394PMC
October 2014

Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors.

J Pediatr Hematol Oncol 2014 Aug;36(6):451-7

Departments of *Pediatrics §Neuro-oncology #Pathology (Division of Neuropathology), Moores UCSD Cancer Center †Pediatrics ‡Neurosciences/Pediatrics, Rady Children's Hospital, University of California San Diego, La Jolla, CA ∥Oncovir Inc. ¶Children's Oncology Group, Childrens Hospital of Orange County, Orange, CA **Department of Pediatrics, Emory University, AFLAC Cancer Center, Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1097/MPH.0000000000000047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356196PMC
August 2014

The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma.

J Immunother Cancer 2014 7;2:21. Epub 2014 Jul 7.

GRU Cancer Center, Georgia Regents University, Augusta, Georgia, 30912, USA ; Program in Cancer immunology, Inflammation and Tolerance (CIT), Georgia Regents University, Augusta, GA, USA ; Medical College of Georgia Department of Pediatrics, Georgia Regents University, 1120 Fifteenth Street, Augusta, GA CN-4141A, USA.

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http://dx.doi.org/10.1186/2051-1426-2-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105871PMC
July 2014

Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres.

Nat Mater 2014 Mar 16;13(3):308-16. Epub 2014 Feb 16.

Neurological Biomaterials and Cancer Therapeutics Laboratory, Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology/Emory University School of Medicine, 313 Ferst Drive, Atlanta Georgia 30332 USA.

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http://www.nature.com/articles/nmat3878
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http://dx.doi.org/10.1038/nmat3878DOI Listing
March 2014

The rationale for targeted therapies in medulloblastoma.

Neuro Oncol 2014 Jan 4;16(1):9-20. Epub 2013 Dec 4.

Corresponding author: Robert C. Castellino, MD, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Health Sciences Research Building, 1760 Haygood Drive NE, Room E394, Atlanta, GA 30322.

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http://dx.doi.org/10.1093/neuonc/not147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870836PMC
January 2014

Phase II study of cilengitide in the treatment of refractory or relapsed high-grade gliomas in children: a report from the Children's Oncology Group.

Neuro Oncol 2013 Oct 5;15(10):1438-44. Epub 2013 Sep 5.

Corresponding Author: Tobey J. MacDonald, MD, Emory Children's Center, Aflac Cancer and Blood Disorders Center, 2015 Uppergate Drive NE, Suite 442, Atlanta, GA 30322.

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http://dx.doi.org/10.1093/neuonc/not058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779033PMC
October 2013

Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience.

Childs Nerv Syst 2013 Apr 8;29(4):589-96. Epub 2013 Jan 8.

Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, 5455 Meridian Mark Rd., NE, Suite 400, Atlanta, GA 30342, USA.

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http://dx.doi.org/10.1007/s00381-012-2013-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963487PMC
April 2013

Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration.

Mol Cancer 2013 Mar 5;12:18. Epub 2013 Mar 5.

Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1186/1476-4598-12-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599655PMC
March 2013

A feasibility and efficacy study of rapamycin and erlotinib for recurrent pediatric low-grade glioma (LGG).

Pediatr Blood Cancer 2013 Jan 20;60(1):71-6. Epub 2012 Mar 20.

The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1002/pbc.24142DOI Listing
January 2013

Prolonged survival after treatment of diffuse intrinsic pontine glioma with radiation, temozolamide, and bevacizumab: report of 2 cases.

J Pediatr Hematol Oncol 2013 Jan;35(1):e42-6

Aflac Center for Cancer and Blood Disorders Service, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1097/MPH.0b013e318279aed8DOI Listing
January 2013

Diffuse intrinsic pontine glioma (DIPG): time to biopsy again?

Pediatr Blood Cancer 2012 Apr;58(4):487-8

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http://dx.doi.org/10.1002/pbc.24090DOI Listing
April 2012

Secretome signature of invasive glioblastoma multiforme.

J Proteome Res 2011 Jul 31;10(7):3149-59. Epub 2011 May 31.

Research Center for Genetic Medicine, Children's National Medical Center, 111 Michigan Avenue NW, Washington, D.C. 20010, USA.

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http://dx.doi.org/10.1021/pr200210wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136381PMC
July 2011

Identification of transcriptional regulatory networks specific to pilocytic astrocytoma.

BMC Med Genomics 2011 Jul 11;4:57. Epub 2011 Jul 11.

Department of Pathology and Immunology, Washington University School of Medicine, 660, S, Euclid Ave, St, Louis, MO 63110, USA.

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http://dx.doi.org/10.1186/1755-8794-4-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200988PMC
July 2011

Characterization of signaling function and expression of HLA class I molecules in medulloblastoma.

J Neurooncol 2011 Jun 2;103(2):197-206. Epub 2010 Sep 2.

Center for Cancer and Immunology Research, Children's Research Institute, Children's National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010-2970, USA.

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http://dx.doi.org/10.1007/s11060-010-0378-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098313PMC
June 2011

Neurofibromatosis-2 and spinal cord ependymomas: Report of two cases and review of the literature.

Childs Nerv Syst 2011 May 4;27(5):757-64. Epub 2010 Dec 4.

Aflac Cancer Center and Blood Disorders Service at Children's Health Care of Atlanta, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1007/s00381-010-1351-3DOI Listing
May 2011

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells.

J Neurooncol 2011 Jan 4;101(2):215-26. Epub 2010 Jun 4.

Children's Research Institute, Center for Cancer and Immunology Research, Children's National Medical Center and The George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.

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http://dx.doi.org/10.1007/s11060-010-0259-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997175PMC
January 2011

ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration.

Clin Exp Metastasis 2010 Oct 6;27(7):481-91. Epub 2010 Jun 6.

Aflac Center for Cancer and Blood Disorders, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1007/s10585-010-9337-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954413PMC
October 2010

Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.

PLoS One 2010 May 26;5(5):e10849. Epub 2010 May 26.

Department of Pediatrics, Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010849PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877103PMC
May 2010

Detection of human herpesvirus-6 in adult central nervous system tumors: predominance of early and late viral antigens in glial tumors.

J Neurooncol 2009 Oct 8;95(1):49-60. Epub 2009 May 8.

Department of Hematology-Oncology, The George Washington University, 111 Michigan Ave NW, Washington, DC, 20010, USA.

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http://dx.doi.org/10.1007/s11060-009-9908-2DOI Listing
October 2009

Detection of human herpesvirus-6 variants in pediatric brain tumors: association of viral antigen in low grade gliomas.

J Clin Virol 2009 Sep 7;46(1):37-42. Epub 2009 Jun 7.

The Department of Neurology, Children's National Medical Center, The George Washington University, Washington, DC, United States.

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http://dx.doi.org/10.1016/j.jcv.2009.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749001PMC
September 2009

A novel role of HLA class I in the pathology of medulloblastoma.

J Transl Med 2009 Jul 12;7:59. Epub 2009 Jul 12.

Center for Cancer and Immunology Research, Children's Research Institute, Children's National Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1186/1479-5876-7-59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714836PMC
July 2009

Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor.

Mol Cancer Ther 2009 May 5;8(5):1137-47. Epub 2009 May 5.

The George Washington University and Center for Cancer and Immunology Research, Children's Research Institute, Washington, District of Columbia 20010, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891380PMC
May 2009

Aggressive infantile embryonal tumors.

J Child Neurol 2008 Oct;23(10):1195-204

Division of Oncology, Center for Cancer and Blood Disorders, Center for Cancer and Immunology Research, Children's Research Institute, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1177/0883073808321769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674573PMC
October 2008

IGFBP2 is overexpressed by pediatric malignant astrocytomas and induces the repair enzyme DNA-PK.

J Child Neurol 2008 Oct;23(10):1205-13

Center for Cancer and Immunology Research, Children's Research Institute, Washington, DC 20010, USA.

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http://dx.doi.org/10.1177/0883073808321766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674842PMC
October 2008

Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas.

Clin Cancer Res 2008 Jun;14(11):3386-94

Division of Hematology-Oncology, Children's National Medical Center, 4th Floor West Wing, 111 Michigan Avenue, Northwest, Washington, DC 20010, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953416PMC
June 2008

Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors.

Pediatr Blood Cancer 2008 May;50(5):970-5

Division of Hematology and Oncology, Children's National Medical Center, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1002/pbc.21381DOI Listing
May 2008

Medulloblastoma in childhood: new biological advances.

Lancet Neurol 2007 Dec;6(12):1073-85

Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Washington DC 20010, USA.

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http://dx.doi.org/10.1016/S1474-4422(07)70289-2DOI Listing
December 2007

Progression-associated genes in astrocytoma identified by novel microarray gene expression data reanalysis.

Methods Mol Biol 2007 ;377:203-22

Center for Cancer and Immunology Research, Children's Research Institute, Department of Hematology-Oncology, Children's National Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1007/978-1-59745-390-5_13DOI Listing
August 2007

Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue.

Pediatr Blood Cancer 2007 Mar;48(3):278-84

Division of Hematology and Oncology, Children's National Medical Center, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1002/pbc.20781DOI Listing
March 2007

An analysis of SEER data of increasing risk of secondary malignant neoplasms among long-term survivors of childhood brain tumors.

Pediatr Blood Cancer 2006 Jul;47(1):83-8

Center for Cancer Research, Children's National Medical Center, Michigan Ave NW, Washington, DC, USA.

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http://dx.doi.org/10.1002/pbc.20690DOI Listing
July 2006

Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches.

J Neurooncol 2005 Dec;75(3):267-72

Division of Hematology/Oncology, Center for Cancer and Immunology Research, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1007/s11060-005-6749-5DOI Listing
December 2005

Current treatment of medulloblastoma: recent advances and future challenges.

Semin Oncol 2004 Oct;31(5):666-75

Division of Hematology/Oncology, Center for Cancer Research, Children's National Medical Center, Washington, DC 20010, USA.

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October 2004

Advances in the diagnosis, molecular genetics, and treatment of pediatric embryonal CNS tumors.

Oncologist 2003 ;8(2):174-86

Departments of Hematology/Oncology, Children's Hospital National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1634/theoncologist.8-2-174DOI Listing
September 2003

Medulloblastoma: present concepts of stratification into risk groups.

Pediatr Neurosurg 2003 Jul;39(2):60-7

Department of Neurology, Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1159/000071316DOI Listing
July 2003

The use of gene expression analysis to gain insights into signaling mechanisms of metastatic medulloblastoma.

Pediatr Neurosurg 2003 Jul;39(2):68-74

Department of Pediatrics, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1159/000071317DOI Listing
July 2003

Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling.

Cancer Res 2003 Apr;63(8):1865-70

Center for Cancer Research, Children's Research Institute, Washington, DC 20010, USA.

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April 2003