Tjeerd Van Staa

Tjeerd Van Staa

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Tjeerd Van Staa

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Antibiotic prescribing for common infections in UK general practice: variability and drivers.

J Antimicrob Chemother 2019 Aug;74(8):2440-2450

Greater Manchester Connected Health Cities, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester M13 9PL, UK.

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http://dx.doi.org/10.1093/jac/dkz163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640319PMC
August 2019

Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study.

Lancet 2019 08 25;394(10199):663-671. Epub 2019 Jul 25.

Department of Non-Communicable Diseases Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Health Data Research UK, London, UK.

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http://dx.doi.org/10.1016/S0140-6736(19)31359-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717081PMC
August 2019

Do population-level risk prediction models that use routinely collected health data reliably predict individual risks?

Sci Rep 2019 Aug 2;9(1):11222. Epub 2019 Aug 2.

Health e-Research Centre, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Sciences Centre (MAHSC), Oxford Road, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1038/s41598-019-47712-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677736PMC
August 2019

Correction to: The uncertainty with using risk prediction models for individual decision making: an exemplar cohort study examining the prediction of cardiovascular disease in English primary care.

BMC Med 2019 Aug 10;17(1):158. Epub 2019 Aug 10.

Centre of Health eResearch, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1186/s12916-019-1404-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689154PMC
August 2019

Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing.

J Antimicrob Chemother 2019 Aug 20. Epub 2019 Aug 20.

Greater Manchester Connected Health Cities, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester M13 9PL, UK.

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http://dx.doi.org/10.1093/jac/dkz345DOI Listing
August 2019

The uncertainty with using risk prediction models for individual decision making: an exemplar cohort study examining the prediction of cardiovascular disease in English primary care.

BMC Med 2019 07 17;17(1):134. Epub 2019 Jul 17.

Centre of Health eResearch, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1186/s12916-019-1368-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636064PMC
July 2019

The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex 'mix-and-match' implementation package.

Eur J Clin Microbiol Infect Dis 2019 Jun 2;38(6):1015-1022. Epub 2019 Feb 2.

Division of Infection and Pathway Medicine, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1007/s10096-019-03492-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520316PMC
June 2019

Evaluation protocol of the implementation of a learning healthcare system in clinical practice: the Connected Health Cities programme in the north of England.

BMJ Open 2019 Jun 4;9(6):e025484. Epub 2019 Jun 4.

Division of Informatics, Imaging and Data Sciences, School of Health Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/bmjopen-2018-025484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561425PMC
June 2019

Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink.

Clin Pharmacol Ther 2019 Jun 20. Epub 2019 Jun 20.

Wolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1002/cpt.1557DOI Listing
June 2019

The use of wearable technology to monitor physical activity in patients with COPD: a literature review.

Int J Chron Obstruct Pulmon Dis 2019 19;14:1317-1322. Epub 2019 Jun 19.

Health eResearch Centre, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.

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http://dx.doi.org/10.2147/COPD.S193037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590412PMC
June 2019

Response to: 'Statins in systemic lupus erythematosus' by Abud-Mendoza.

Ann Rheum Dis 2019 May 22;78(5):e43. Epub 2018 Jan 22.

School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2017-212902DOI Listing
May 2019

Exposure measurement error when assessing current glucocorticoid use using UK primary care electronic prescription data.

Pharmacoepidemiol Drug Saf 2019 Feb 28;28(2):179-186. Epub 2018 Sep 28.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/pds.4649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492099PMC
February 2019

Term sets: A transparent and reproducible representation of clinical code sets.

PLoS One 2019 14;14(2):e0212291. Epub 2019 Feb 14.

Greater Manchester Patient Safety Translational Research Centre, University of Manchester, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212291PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375602PMC
February 2019

Relationship between prescribing of antibiotics and other medicines in primary care: a cross-sectional study.

Br J Gen Pract 2019 Jan 17;69(678):e42-e51. Epub 2018 Dec 17.

Health e-Research Centre, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK, and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

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http://dx.doi.org/10.3399/bjgp18X700457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301355PMC
January 2019

Using marginal structural models to adjust for treatment drop-in when developing clinical prediction models.

Stat Med 2018 12 2;37(28):4142-4154. Epub 2018 Aug 2.

Farr Institute, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/sim.7913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282523PMC
December 2018

The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study.

Bone 2018 12 13;117:83-90. Epub 2018 Sep 13.

Arthritis Research UK Centre for Epidemiology, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester M13 9PT, UK; Health eResearch Centre, Farr Institute for Health Informatics Research, University of Manchester, Vaughan House, Portsmouth Road, M13 9PL, UK; NIHR Manchester Biomedical Research Centre, Manchester University, NHS Foundation Trust, Manchester Academic Health Science Centre, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282183034
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http://dx.doi.org/10.1016/j.bone.2018.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173307PMC
December 2018

Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records.

RMD Open 2018 1;4(2):e000700. Epub 2018 Oct 1.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2018-00070
Publisher Site
http://dx.doi.org/10.1136/rmdopen-2018-000700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173262PMC
October 2018

Antibiotic prescribing patterns in general medical practices in England: Does area matter?

Health Place 2018 09 19;53:10-16. Epub 2018 Jul 19.

Greater Manchester Connected Health Cities, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Oxford Road, Manchester M13 9PL, UK.

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http://dx.doi.org/10.1016/j.healthplace.2018.07.004DOI Listing
September 2018

Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies.

Pharmacoepidemiol Drug Saf 2018 07 17;27(7):781-788. Epub 2018 Apr 17.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/pds.4440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055712PMC
July 2018

Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink.

PLoS One 2018 23;13(2):e0193297. Epub 2018 Feb 23.

Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193297PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825093PMC
May 2018

Supplementing electronic health records through sample collection and patient diaries: A study set within a primary care research database.

Pharmacoepidemiol Drug Saf 2018 02 19;27(2):239-242. Epub 2017 Sep 19.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/pds.4323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846885PMC
February 2018

A nationwide cohort study of slipped capital femoral epiphysis.

Arch Dis Child 2017 12 29;102(12):1132-1136. Epub 2017 Jun 29.

Health eResearch Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2016-312328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754864PMC
December 2017

Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study.

Ann Rheum Dis 2017 Oct 6;76(10):1723-1730. Epub 2017 Jul 6.

School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2016-210936DOI Listing
October 2017

Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study.

J Antimicrob Chemother 2017 09;72(9):2636-2646

Department of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1093/jac/dkx183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890755PMC
September 2017

Drug therapy for alcohol dependence in primary care in the UK: A Clinical Practice Research Datalink study.

PLoS One 2017 20;12(3):e0173272. Epub 2017 Mar 20.

Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173272PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358741PMC
August 2017

Epidemiology of alcohol dependence in UK primary care: Results from a large observational study using the Clinical Practice Research Datalink.

PLoS One 2017 31;12(3):e0174818. Epub 2017 Mar 31.

Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174818PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376077PMC
August 2017

Cost-effectiveness of antibiotics for COPD management: observational analysis using CPRD data.

ERJ Open Res 2017 Apr 19;3(2). Epub 2017 Jun 19.

Health eResearch Centre, Farr Institute for Health Informatics Research, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1183/23120541.00085-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478862PMC
April 2017

Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study.

Scand J Work Environ Health 2017 03 4;43(2):136-145. Epub 2017 Jan 4.

Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK.

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http://www.sjweh.fi/show_abstract.php?abstract_id=3618
Publisher Site
http://dx.doi.org/10.5271/sjweh.3618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367516PMC
March 2017

Erratum to: Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study.

BMC Med Res Methodol 2017 03 22;17(1):47. Epub 2017 Mar 22.

Health eResearch Centre, Farr Institute for Health Informatics Research, University of Manchester, Vaughan House, Portsmouth Road, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1186/s12874-017-0326-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363037PMC
March 2017

Better care through better use of data in GP-patient partnerships.

Br J Gen Pract 2017 Feb;67(655):54-55

Health eResearch Centre, Farr Institute of Health Informatics Research, Centre for Health Informatics, University of Manchester, Manchester.

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http://dx.doi.org/10.3399/bjgp17X688921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308088PMC
February 2017

Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study.

BMC Med Res Methodol 2017 01 31;17(1):17. Epub 2017 Jan 31.

Health eResearch Centre, Farr Institute for Health Informatics Research, University of Manchester, Vaughan House, Portsmouth Road, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1186/s12874-017-0295-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282910PMC
January 2017

On epidemiology of fractures and variation with age and ethnicity.

Bone 2016 12 17;93:230-231. Epub 2016 Jul 17.

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton SO16 6YD, UK; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton SO16 6YD, UK; NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Nuffield Orthopedic Centre, Headington, Oxford OX3 7HE, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081095PMC
http://dx.doi.org/10.1016/j.bone.2016.07.011DOI Listing
December 2016

Real-Life and RCT Participants: Alendronate Users Versus FITs' Trial Eligibility Criterion.

Calcif Tissue Int 2016 09 20;99(3):243-9. Epub 2016 Apr 20.

GREMPAL Research Group, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Universitat Autònoma de Barcelona, Gran Via Corts Catalanes 587, 08007, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00223-016-0141-7DOI Listing
September 2016

Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury.

BMJ Open 2016 09 2;6(9):e012102. Epub 2016 Sep 2.

Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2016-012102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020862PMC
September 2016

Job dissatisfaction and the older worker: baseline findings from the Health and Employment After Fifty study.

Occup Environ Med 2016 08 5;73(8):512-9. Epub 2016 May 5.

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK Arthritis Research UK/MRC Centre for Musculoskeletal Health and Work, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1136/oemed-2016-103591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962897PMC
August 2016

Cohort Multiple Randomised Controlled Trials (cmRCT) design: efficient but biased? A simulation study to evaluate the feasibility of the Cluster cmRCT design.

BMC Med Res Methodol 2016 08 26;16(1):109. Epub 2016 Aug 26.

Health eResearch Centre, Farr Institute for Health Informatics Research, University of Manchester, 1.003 Vaughan House, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1186/s12874-016-0208-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000409PMC
August 2016

Insulin glargine use and breast cancer risk: Associations with cumulative exposure.

Acta Oncol 2016 Jul 6;55(7):851-8. Epub 2016 May 6.

a Utrecht Institute for Pharmaceutical Sciences, Utrecht University , The Netherlands ;

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http://dx.doi.org/10.3109/0284186X.2016.1155736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975082PMC
July 2016

Epidemiology of fractures in the United Kingdom 1988-2012: Variation with age, sex, geography, ethnicity and socioeconomic status.

Bone 2016 06 9;87:19-26. Epub 2016 Mar 9.

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton SO16 6YD, UK; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1016/j.bone.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890652PMC
June 2016

Ethnic and geographic variations in the epidemiology of childhood fractures in the United Kingdom.

Bone 2016 Apr 21;85:9-14. Epub 2016 Jan 21.

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK; NIHR Southampton Nutrition Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK, SO16 6YD, UK; NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, OX3 7LD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841386PMC
April 2016

Comparative Performance of ATRIA, CHADS2, and CHA2DS2-VASc Risk Scores Predicting Stroke in Patients With Atrial Fibrillation: Results From a National Primary Care Database.

J Am Coll Cardiol 2015 Oct;66(17):1851-9

Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; Department of Health eResearch, University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.08.033DOI Listing
October 2015

Left truncation results in substantial bias of the relation between time-dependent exposures and adverse events.

Ann Epidemiol 2015 Aug 1;25(8):590-6. Epub 2015 Apr 1.

Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.annepidem.2015.03.019DOI Listing
August 2015

Using linkage to electronic primary care records to evaluate recruitment and nonresponse bias in the Avon Longitudinal Study of Parents and Children.

Epidemiology 2015 Jul;26(4):e41-2

School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom Health e-Research Centre, University of Manchester, Manchester, United Kingdom Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000000288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454477PMC
July 2015

Data Resource Profile: Clinical Practice Research Datalink (CPRD).

Int J Epidemiol 2015 Jun 6;44(3):827-36. Epub 2015 Jun 6.

London School of Hygiene & Tropical Medicine, London, UK.

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http://dx.doi.org/10.1093/ije/dyv098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131PMC
June 2015

Performance of prior event rate ratio adjustment method in pharmacoepidemiology: a simulation study.

Pharmacoepidemiol Drug Saf 2015 May 20;24(5):468-77. Epub 2014 Nov 20.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/pds.3724DOI Listing
May 2015

The identification of incident cancers in UK primary care databases: a systematic review.

Pharmacoepidemiol Drug Saf 2015 Jan 24;24(1):11-8. Epub 2014 Nov 24.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1002/pds.3729DOI Listing
January 2015

Predictors and outcomes of increases in creatine phosphokinase concentrations or rhabdomyolysis risk during statin treatment.

Br J Clin Pharmacol 2014 Sep;78(3):649-59

London School of Hygiene & Tropical Medicine, London, UK; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/bcp.12367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243915PMC
September 2014

Point-of-care cluster randomized trial in stroke secondary prevention using electronic health records.

Stroke 2014 Jul 5;45(7):2066-71. Epub 2014 Jun 5.

From the Department of Primary Care and Public Health Sciences, King's College London, London, United Kingdom (A.D., L.M., M.A., J.C., C.D.A.W., A.R., M.C.G.); NIHR Biomedical Research Centre at Guy's and St Thomas' Hospital London, London, United Kingdom (A.D., C.D.A.W., A.R., M.C.G.); Clinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, United Kingdom (T.P.v.S., G.M.); London School of Hygiene & Tropical Medicine, London, United Kingdom (T.P.v.S.); and Division of Community Clinical Sciences, University of Southampton, Southampton, United Kingdom (L.M., L.Y.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005713DOI Listing
July 2014

Cluster randomized trials utilizing primary care electronic health records: methodological issues in design, conduct, and analysis (eCRT Study).

Trials 2014 Jun 11;15:220. Epub 2014 Jun 11.

Department of Primary Care and Public Health Sciences, King's College London, Capital House, 42 Weston St, London SE1 3QD, UK.

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http://dx.doi.org/10.1186/1745-6215-15-220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062282PMC
June 2014

Bridging differences in outcomes of pharmacoepidemiological studies: design and first results of the PROTECT project.

Curr Clin Pharmacol 2014 May;9(2):130-8

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, P.O. Box 80082 3508 TB Utrecht, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083447PMC
May 2014

Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records.

Drug Discov Today 2014 Apr 14;19(4):361-6. Epub 2013 Nov 14.

Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK; Department of Pharmacoepidemiology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands; Clinical Practice Research Datalink (CPRD), Medicines and Healthcare Products Regulatory Agency, London, UK.

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http://dx.doi.org/10.1016/j.drudis.2013.11.003DOI Listing
April 2014

Validating childhood asthma in an epidemiological study using linked electronic patient records.

BMJ Open 2014 Apr 23;4(4):e005345. Epub 2014 Apr 23.

School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjopen-2014-005345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010849PMC
April 2014

Changes in mortality patterns following total hip or knee arthroplasty over the past two decades: a nationwide cohort study.

Arthritis Rheumatol 2014 Feb;66(2):311-8

Utrecht University and University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/art.38232DOI Listing
February 2014

Risk of mortality (including sudden cardiac death) and major cardiovascular events in atypical and typical antipsychotic users: a study with the general practice research database.

Cardiovasc Psychiatry Neurol 2013 26;2013:247486. Epub 2013 Dec 26.

Clinical Practice Research Datalink, Medicines and Healthcare Products Regulatory Agency, London SWIW 9SZ, UK ; London School of Hygiene & Tropical Medicine, London, UK ; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1155/2013/247486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888674PMC
January 2014

Risk of gastrointestinal bleeding in patients undergoing total hip or knee replacement compared with matched controls: a nationwide cohort study.

Am J Gastroenterol 2013 Aug 30;108(8):1277-85. Epub 2013 Apr 30.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/ajg.2013.108DOI Listing
August 2013

Mortality associations with long-term exposure to outdoor air pollution in a national English cohort.

Am J Respir Crit Care Med 2013 Jun;187(11):1226-33

Division of Population Health Sciences and Education and MRC-PHE Centre for Environment and Health, St George's, University of London, London, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201210-1758OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734610PMC
June 2013

Cancer recording and mortality in the General Practice Research Database and linked cancer registries.

Pharmacoepidemiol Drug Saf 2013 Feb 13;22(2):168-75. Epub 2012 Dec 13.

Clinical Practice Research Datalink, Medicines and Healthcare Products Regulatory Agency, London, UK.

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http://dx.doi.org/10.1002/pds.3374DOI Listing
February 2013

Long-term exposure to outdoor air pollution and incidence of cardiovascular diseases.

Epidemiology 2013 Jan;24(1):44-53

Division of Population Health Sciences and Education and MRC-HPA Centre for Environment and Health, St George's, University of London, London, United Kingdom.

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http://dx.doi.org/10.1097/EDE.0b013e318276ccb8DOI Listing
January 2013

Timing of stroke in patients undergoing total hip replacement and matched controls: a nationwide cohort study.

Stroke 2012 Dec 6;43(12):3225-9. Epub 2012 Nov 6.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1161/STROKEAHA.112.668509DOI Listing
December 2012

Regional and temporal variation in the treatment of rheumatoid arthritis across the UK: a descriptive register-based cohort study.

BMJ Open 2012 8;2(6). Epub 2012 Nov 8.

Department of Rheumatology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1136/bmjopen-2012-001603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533005PMC
November 2012

Timing of acute myocardial infarction in patients undergoing total hip or knee replacement: a nationwide cohort study.

Arch Intern Med 2012 Sep;172(16):1229-35

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, the Netherlands.

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http://dx.doi.org/10.1001/archinternmed.2012.2713DOI Listing
September 2012

Resource utilization and outcomes in patients with atrial fibrillation: a case control study.

Appl Health Econ Health Policy 2012 Jul;10(4):249-59

Clinical Practice Research Datalink, Medicines and Healthcare products Regulatory Agency, London, UK.

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http://dx.doi.org/10.2165/11599940-000000000-00000DOI Listing
July 2012

Will the revolution in genetics improve healthcare?

BMJ 2012 Jul 20;345:e4651. Epub 2012 Jul 20.

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http://dx.doi.org/10.1136/bmj.e4651DOI Listing
July 2012