Dr. Tiziano Scarabelli, MD, PhD - SJHS -

Dr. Tiziano Scarabelli

MD, PhD

SJHS

Richmond , Virginia | United States

Additional Specialties: Internal Medicine; Cardiology

Dr. Tiziano Scarabelli, MD, PhD - SJHS -

Dr. Tiziano Scarabelli

MD, PhD

Introduction

Primary Affiliation: SJHS - Richmond , Virginia , United States

Additional Specialties:

Research Interests:

Publications

65Publications

1062Reads

1205Profile Views

2PubMed Central Citations

Urocortin Induces Phosphorylation of Distinct Residues of Signal Transducer and Activator of Transcription 3 (STAT3) via Different Signaling Pathways.

Med Sci Monit Basic Res 2019 May 10;25:139-152. Epub 2019 May 10.

Center for Heart and Vessel Preclinical Studies, Department of Internal Medicine, St. John Hospital and Medical Center, Wayne State University, Detroit, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12659/MSMBR.914611DOI Listing
May 2019
6 Reads

Heart Failure Progression During Cardiotoxic Chemotherapy.

JACC Heart Fail 2019 Apr;7(4):365-367

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchf.2018.12.011DOI Listing
April 2019
2 Reads

Autophagy and Oncosis/Necroptosis Are Enhanced in Cardiomyocytes from Heart Failure Patients.

Med Sci Monit Basic Res 2019 Feb 4;25:33-44. Epub 2019 Feb 4.

Center for Heart and Vessel Preclinical Studies, Department of Internal Medicine, St. John Hospital and Medical Center, Wayne State University, Detroit, MI, USA.

View Article

Download full-text PDF

Source
https://basic.medscimonit.com/abstract/index/idArt/913436
Publisher Site
http://dx.doi.org/10.12659/MSMBR.913436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373236PMC
February 2019
29 Reads

Cardio-oncology: an evolving hybrid subspecialty.

Future Cardiol 2018 05 22;14(3):197-201. Epub 2018 Jan 22.

Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University (VCU) Medical Center, Richmond, VA 23219, USA.

View Article

Download full-text PDF

Source
https://www.futuremedicine.com/doi/10.2217/fca-2017-0080
Publisher Site
http://dx.doi.org/10.2217/fca-2017-0080DOI Listing
May 2018
11 Reads

The ethics of radiation exposure in cancer-treated patients : Editorial for: Frequent MUGA testing in a myeloma patient: a case-based ethics discussion.

J Nucl Cardiol 2017 08 16;24(4):1355-1360. Epub 2016 Jun 16.

Birmingham Veterans Affairs Medical Center, University of Alabama at Birmingham, 1530 3rd Avenue, South Tinsley Harrison Tower, Birmingham, AL, 35294-0006, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12350-016-0567-3DOI Listing
August 2017
9 Reads
2.942 Impact Factor

Comprehensive review on cardio-oncology: Role of multimodality imaging.

J Nucl Cardiol 2017 06 25;24(3):906-935. Epub 2016 May 25.

Birmingham Veterans Affairs Medical Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12350-016-0535-yDOI Listing
June 2017
17 Reads
2.942 Impact Factor

Editor Highlight Interview: Multi-modality imaging and clinical issues in cardio-oncology.

J Nucl Cardiol 2017 06;24(3):936-937

Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, 318 LHRB/1900 University BLVD, Birmingham, AL, 35294, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12350-016-0536-xDOI Listing
June 2017
6 Reads
2.942 Impact Factor

Diagnostic Approach to Myocarditis Mimicking Myocardial Infarction at Initial Presentation.

Cardiol Res 2016 Dec 31;7(6):209-213. Epub 2016 Dec 31.

St John Hospital and Medical Center, Wayne State University School of Medicine, Detroit, MI, USA; University of Alabama at Birmingham (UAB) Medical Center, Birmingham, Alabama, AL, USA; Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14740/cr485wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295512PMC
December 2016
13 Reads

Syncope While Driving in Denmark.

JAMA Intern Med 2016 08;176(8):1230

Birmingham VA Medical Center, Birmingham, Alabama2University of Alabama at Birmingham (UAB) Medical Center, Birmingham, Alabama.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamainternmed.2016.3723DOI Listing
August 2016
17 Reads

Current strategies in the evaluation and management of cocaine-induced chest pain.

Cardiol Rev 2015 Nov-Dec;23(6):303-11

From the *Department of Medicine, Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India; †Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, NY; ‡Department of Internal Medicine, St John Hospital and Medical Center, Wayne State University School of Medicine, Detroit, MI; §Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL; and ¶VA Ann Arbor Health Care System, University of Michigan, Ann Arbor, MI.

View Article

Download full-text PDF

Source
http://pdfs.journals.lww.com/cardiologyinreview/2015/11000/C
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/CRD.0000000000000050DOI Listing
July 2016
44 Reads
2.410 Impact Factor

Cyclosporine A Prior to Primary PCI in STEMI Patients: The Coup de Grâce to Post-Conditioning?

J Am Coll Cardiol 2016 Feb;67(4):375-378

Birmingham Veterans Affairs Medical Center, University of Alabama at Birmingham, Birmingham, Alabama; Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2015.11.024DOI Listing
February 2016
14 Reads
16.503 Impact Factor

Device-detected atrial fibrillation: what to do with asymptomatic patients?

J Am Coll Cardiol 2015 Jan;65(3):281-94

Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2014.10.045DOI Listing
January 2015
8 Reads
16.503 Impact Factor

Dilemmas in end-stage heart failure.

J Geriatr Cardiol 2015 Jan;12(1):57-65

St. John Hospital and Medical Center/Wayne State University, 22101 Moross Rd., Detroit, MI 48236, USA ; Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, One Gustave L. Levy Place, Box 1030, New York, NY 10029-6574, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308459PMC
January 2015
13 Reads
1.060 Impact Factor

The role and modulation of autophagy in experimental models of myocardial ischemia-reperfusion injury.

J Geriatr Cardiol 2014 Dec;11(4):338-48

Medical and Molecular Biology Unit, University College London, UCL, 30 Guildford St., London, WC1N 1EH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11909/j.issn.1671-5411.2014.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294150PMC
December 2014
13 Reads
1.060 Impact Factor

Diabetic hearts have lower basal urocortin levels that fail to increase after cardioplegic arrest: association with increased apoptosis and postsurgical cardiac dysfunction.

J Thorac Cardiovasc Surg 2014 Nov 14;148(5):2296-308. Epub 2014 May 14.

Center for Heart and Vessel Preclinical Studies, St John Hospital and Medical Center, Wayne State University, Detroit, Mich; Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

View Article

Download full-text PDF

Source
http://ac.els-cdn.com/S0022522314005546/1-s2.0-S002252231400
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S002252231400554
Publisher Site
http://dx.doi.org/10.1016/j.jtcvs.2014.05.018DOI Listing
November 2014
43 Reads
4.170 Impact Factor

Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury.

Int J Cardiol 2013 03 24;163(3):326-334. Epub 2011 Oct 24.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2011.08.849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581775PMC
March 2013
30 Reads
4.040 Impact Factor

A critical review of the use of carvedilol in ischemic heart disease.

Am J Cardiovasc Drugs 2012 Dec;12(6):391-401

Center for Heart and Vessel Preclinical Studies, St John Hospital and Medical Center, Wayne State University School of Medicine, Detroit, MI 48236, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2165/11636090-000000000-00000DOI Listing
December 2012
18 Reads
2.203 Impact Factor

STAT transcription in the ischemic heart.

JAKSTAT 2012 Apr;1(2):111-7

Medical Molecular Biology Unit; University College London; London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/jkst.20078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670290PMC
April 2012
7 Reads

Autophagy in mammalian cells.

World J Biol Chem 2012 Jan;3(1):1-6

Kadija Abounit, Tiziano M Scarabelli, Roy B McCauley, Department of Pharmacology, School of Medicine, Wayne State University, Detroit , MI 48201, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4331/wjbc.v3.i1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272585PMC
January 2012
8 Reads

Autophagy in the stress-induced myocardium.

Front Biosci (Elite Ed) 2012 Jan 1;4:2131-41. Epub 2012 Jan 1.

The Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH.

View Article

Download full-text PDF

Source
January 2012
5 Reads

The role of minocycline in ischemia-reperfusion injury: a comprehensive review of an old drug with new implications.

Recent Pat Cardiovasc Drug Discov 2011 May;6(2):123-32

Center for Heart and Vessel Preclinical Studies, St. John Hospital and Medical Center, Wayne State University School of Medicine, USA.

View Article

Download full-text PDF

Source
May 2011
12 Reads

STAT3 modulates the DNA damage response pathway.

Int J Exp Pathol 2010 Dec 27;91(6):506-14. Epub 2010 Aug 27.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2613.2010.00734.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010549PMC
December 2010
10 Reads
2.170 Impact Factor

New targets of urocortin-mediated cardioprotection.

J Mol Endocrinol 2010 Aug 25;45(2):69-85. Epub 2010 May 25.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1677/JME-09-0148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069736PMC
August 2010
25 Reads
3.081 Impact Factor

Mechanisms of action and clinical implications of cardiac urocortin: a journey from the heart to the systemic circulation, with a stopover in the mitochondria.

Int J Cardiol 2009 Nov 29;137(3):189-94. Epub 2009 Apr 29.

Center for Heart and Vessel Preclinical Studies, St John Hospital and Medical Center, Wayne State University Medical School, Detroit, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2009.03.112DOI Listing
November 2009
18 Reads
4.040 Impact Factor

T-wave inversion: cardiac memory or myocardial ischemia?

Am J Emerg Med 2009 Sep;27(7):898.e1-4

VA Ann Arbor/University of Michigan Healthcare System, Ann Arbor, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajem.2008.10.037DOI Listing
September 2009
15 Reads
1.152 Impact Factor

STAT3 deletion sensitizes cells to oxidative stress.

Biochem Biophys Res Commun 2009 Jul 18;385(3):324-9. Epub 2009 May 18.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N1EH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2009.05.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706948PMC
July 2009
11 Reads
2.300 Impact Factor

Referencing for reviews: How to distinguish unwillingness from mission impossible.

Int J Cardiol 2008 Jun 28;127(1):144-5. Epub 2007 Nov 28.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2007.07.135DOI Listing
June 2008
7 Reads
4.040 Impact Factor

Cardiac release of urocortin precedes the occurrence of irreversible myocardial damage in the rat heart exposed to ischemia/reperfusion injury.

FEBS Lett 2008 Mar 22;582(6):984-90. Epub 2008 Feb 22.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2008.02.035DOI Listing
March 2008
16 Reads
3.170 Impact Factor

Peripartum cardiomyopathy: a comprehensive review.

Int J Cardiol 2007 Jun 17;118(3):295-303. Epub 2007 Jan 17.

Center for Heart and Vessel Preclinical Studies, Division of Cardiology, St John Hospital and Medical Center, Wayne State University, Detroit, MI 48236, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2006.08.005DOI Listing
June 2007
11 Reads
4.040 Impact Factor

[Urocortin: molecular biology and cardiovascular effects].

G Ital Cardiol (Rome) 2007 Apr;8(4):236-45

Sezione di Cardiologia, Dipartimento di Medicina Sperimentale e Applicata, Università degli Studi, Brescia.

View Article

Download full-text PDF

Source
April 2007
9 Reads

Chronic renal insufficiency is an independent predictor of mortality in implantable cardioverter-defibrillator recipients.

Pacing Clin Electrophysiol 2007 Mar;30(3):371-6

VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8159.2007.00677.xDOI Listing
March 2007
8 Reads
1.250 Impact Factor

Erythropoietin: new horizon in cardiovascular medicine.

Recent Pat Cardiovasc Drug Discov 2007 Jan;2(1):5-12

Center for Heart & Vessel Preclinical Studies, Division of Cardiology, St John Hospital and Medical Center, Wayne State University, Detroit, MI, USA.

View Article

Download full-text PDF

Source
January 2007
8 Reads

Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury.

J Mol Cell Cardiol 2006 Jun 12;40(6):846-52. Epub 2006 May 12.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yjmcc.2006.03.428DOI Listing
June 2006
8 Reads
4.660 Impact Factor

Clinical implications of apoptosis in ischemic myocardium.

Curr Probl Cardiol 2006 Mar;31(3):181-264

Division of Cardiovascular Disease, Department of Medicine, Wayne State University, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cpcardiol.2005.11.002DOI Listing
March 2006
10 Reads
3.000 Impact Factor

Suboptimal glycemic control, independently of QT interval duration, is associated with increased risk of ventricular arrhythmias in a high-risk population.

Pacing Clin Electrophysiol 2006 Jan;29(1):9-14

Division of Cardiology, VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8159.2006.00298.xDOI Listing
January 2006
18 Reads
1.250 Impact Factor

Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis.

FASEB J 2004 Oct 19;18(13):1621-3. Epub 2004 Aug 19.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.04-1716fjeDOI Listing
October 2004
12 Reads
5.043 Impact Factor

Turning necrosis into apoptosis: the exacting task that can enhance survival.

Am Heart J 2004 Aug;148(2):196-9

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ahj.2004.03.030DOI Listing
August 2004
6 Reads
4.463 Impact Factor

Neurocardiogenic syncope.

BMJ 2004 Aug;329(7461):336-41

VA Ann Arbor Healthcare System, Division of Cardiology (111A), 2215 Fuller Road, Ann Arbor, MI 48105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.329.7461.336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC506859PMC
August 2004
15 Reads

Myocardial injury and cardiac troponin I release after off-pump versus on-pump coronary surgery.

Circulation 2004 Jul;110(4):e36; author reply e36

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.CIR.0000139384.27259.65DOI Listing
July 2004
7 Reads
14.430 Impact Factor

Effect of amino acid mixture on the isolated ischemic heart.

Am J Cardiol 2004 Apr;93(8A):30A-34A

Service of Metabolic and Nutritional Pathophysiology, Salvatore Maugeri Foundation, IRCCS, Medical Center of Montescano, Pavia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2003.11.007DOI Listing
April 2004
13 Reads
3.280 Impact Factor

Nutritional supplementation with mixed essential amino acids enhances myocyte survival, preserving mitochondrial functional capacity during ischemia-reperfusion injury.

Am J Cardiol 2004 Apr;93(8A):35A-40A

Division of Cardiology, St. John Hospital and Medical Center, Wayne State University, Detroit, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2003.11.008DOI Listing
April 2004
19 Reads
3.280 Impact Factor

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis.

J Biol Chem 2004 Feb 5;279(7):5811-20. Epub 2003 Nov 5.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M302637200DOI Listing
February 2004
12 Reads
4.573 Impact Factor

Fungal endocarditis due to Scopulariopsis.

Ann Intern Med 2003 Nov;139(9):W77

View Article

Download full-text PDF

Source
November 2003
10 Reads
17.810 Impact Factor

The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes.

FASEB J 2002 Nov 5;16(13):1841-3. Epub 2002 Sep 5.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London WC1N 1EH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.02-0150fjeDOI Listing
November 2002
15 Reads
5.043 Impact Factor

Urocortin promotes hemodynamic and bioenergetic recovery and improves cell survival in the isolated rat heart exposed to ischemia/reperfusion.

J Am Coll Cardiol 2002 Jul;40(1):155-61

Medical Molecular Biology Unit, Institute of Child Health and Great Ormond Street Hospital, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
July 2002
12 Reads
16.503 Impact Factor

Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury.

Circ Res 2002 Apr;90(6):745-8

Medical Molecular Biology Unit, Institute of Child Health, University College London, UK.

View Article

Download full-text PDF

Source
April 2002
12 Reads
11.020 Impact Factor

Antiapoptotic activity of the free caspase recruitment domain of procaspase-9: a novel endogenous rescue pathway in cell death.

J Biol Chem 2002 Apr 1;277(16):13693-9. Epub 2002 Feb 1.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M108530200DOI Listing
April 2002
12 Reads
4.573 Impact Factor

Top co-authors

Anastasis Stephanou
Anastasis Stephanou

Institute of Child Health

27
Louis Saravolatz
Louis Saravolatz

St John Hospital and Medical Center

26
Richard A Knight
Richard A Knight

Medical Research Council Toxicology Unit

18
David S Latchman
David S Latchman

University of London

17
Giuseppe Faggian
Giuseppe Faggian

University of Verona

15
Paul A Townsend
Paul A Townsend

Institute of Child Health

12
Richard Knight
Richard Knight

Houston Methodist Hospital

11
Evasio Pasini
Evasio Pasini

Scientific Institute of Lumezzane

10
Alessandro Mazzucco
Alessandro Mazzucco

University of Verona

9