Publications by authors named "Tiziana Nardo"

38 Publications

A damaged DNA binding protein 2 mutation disrupting interaction with proliferating-cell nuclear antigen affects DNA repair and confers proliferation advantage.

Authors:
Paola Perucca Roberto Mocchi Isabella Guardamagna Elisabetta Bassi Sabrina Sommatis Tiziana Nardo Ennio Prosperi Lucia Anna Stivala Ornella Cazzalini

Biochim Biophys Acta Mol Cell Res 2018 Jun 28;1865(6):898-907. Epub 2018 Mar 28.

Dipartimento di Medicina Molecolare, Unità di Immunologia e Patologia generale, Università degli Studi di Pavia, Pavia, Italy. Electronic address:

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June 2018

Functional and clinical relevance of novel mutations in a large cohort of patients with Cockayne syndrome.

Authors:
Nadege Calmels Elena Botta Nan Jia Heather Fawcett Tiziana Nardo Yuka Nakazawa Manuela Lanzafame Shinichi Moriwaki Katsuo Sugita Masaya Kubota Cathy Obringer Marie-Aude Spitz Miria Stefanini Vincent Laugel Donata Orioli Tomoo Ogi Alan Robert Lehmann

J Med Genet 2018 05 23;55(5):329-343. Epub 2018 Mar 23.

Genome Damage and Stability Centre, University of Sussex, Brighton, UK.

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May 2018

Thyroid hormone regulates fibronectin expression through the activation of the hypoxia inducible factor 1.

Authors:
Ludovica Taglieri Tiziana Nardo Roberto Vicinanza Jaime M Ross Susanna Scarpa Giuseppe Coppotelli

Biochem Biophys Res Commun 2017 11 30;493(3):1304-1310. Epub 2017 Sep 30.

Department of Genetics, Harvard Medical School, Boston, MA, USA. Electronic address:

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November 2017

GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy.

Authors:
Christiane Kuschal Elena Botta Donata Orioli John J Digiovanna Sara Seneca Kathelijn Keymolen Deborah Tamura Elizabeth Heller Sikandar G Khan Giuseppina Caligiuri Manuela Lanzafame Tiziana Nardo Roberta Ricotti Fiorenzo A Peverali Robert Stephens Yongmei Zhao Alan R Lehmann Laura Baranello David Levens Kenneth H Kraemer Miria Stefanini

Am J Hum Genet 2016 Apr 17;98(4):627-42. Epub 2016 Mar 17.

Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche, Via Abbiategrasso 207, 27100 Pavia, Italy. Electronic address:

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April 2016

Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect.

Authors:
Hiva Fassihi Mieran Sethi Heather Fawcett Jonathan Wing Natalie Chandler Shehla Mohammed Emma Craythorne Ana M S Morley Rongxuan Lim Sally Turner Tanya Henshaw Isabel Garrood Paola Giunti Tammy Hedderly Adesoji Abiona Harsha Naik Gemma Harrop David McGibbon Nicolaas G J Jaspers Elena Botta Tiziana Nardo Miria Stefanini Antony R Young Robert P E Sarkany Alan R Lehmann

Proc Natl Acad Sci U S A 2016 Mar 16;113(9):E1236-45. Epub 2016 Feb 16.

Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, United Kingdom;

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March 2016

PolyDOPA Mussel-Inspired Coating as a Means for Hydroxyapatite Entrapment on Polytetrafluoroethylene Surface for Application in Periodontal Diseases.

Authors:
Tiziana Nardo Valeria Chiono Gianluca Ciardelli Maryam Tabrizian

Macromol Biosci 2016 Feb 7;16(2):288-98. Epub 2015 Oct 7.

Department of Biomedical Engineering, 740 Penfield - Genome Building, Room 4300, McGillUniversity, Montreal, H3A 0G1 Quebec, Canada.

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February 2016

Melanoma of the lower extremities: foot site is an independent risk factor for clinical outcome.

Authors:
Martina Sanlorenzo Simona Osella-Abate Simone Ribero Federica Marenco Tiziana Nardò Maria Teresa Fierro Mauro Novelli Ornella Cervetti Maria Grazia Bernengo Pietro Quaglino

Int J Dermatol 2015 Sep 6;54(9):1023-9. Epub 2015 Feb 6.

Section of Dermatology, Department of Medical Sciences, University of Turin, Turin, Italy.

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September 2015

A novel X-linked trichothiodystrophy associated with a nonsense mutation in RNF113A.

Authors:
Mark A Corbett Tracy Dudding-Byth Patricia A Crock Elena Botta Louise M Christie Tiziana Nardo Giuseppina Caligiuri Lynne Hobson Jackie Boyle Albert Mansour Kathryn L Friend Jo Crawford Graeme Jackson Lucianne Vandeleur Anna Hackett Patrick Tarpey Michael R Stratton Gillian Turner Jozef Gécz Michael Field

J Med Genet 2015 Apr 22;52(4):269-74. Epub 2015 Jan 22.

Genetics of Learning Disability Service, Hunter Genetics, Waratah, Australia.

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April 2015

Cranial nerve and cauda equina contrast enhancement in Cockayne syndrome.

Authors:
Roberta Biancheri Maria Margherita Mancardi Maria Elena Celle Tiziana Nardo Giovanni Morana

Neurology 2014 Oct;83(17):1581

From Istituto G. Gaslini (R.B., M.M.M., M.E.C., G.M.), Genova; and Istituto di Genetica Molecolare del CNR (T.N.), Pavia, Italy.

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October 2014

Adhesion to type V collagen enhances staurosporine-induced apoptosis of adrenocortical cancer cells.

Authors:
Tiziana Nardo Geraldina Micalizzi Roberto Vicinanza Francesca De Iuliis Ludovica Taglieri Susanna Scarpa

Tumour Biol 2014 Oct 10;35(10):9949-55. Epub 2014 Jul 10.

Experimental Medicine Department, Sapienza University of Rome, 00161, Rome, Italy.

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October 2014

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.

Authors:
Ornella Cazzalini Sabrina Sommatis Micol Tillhon Ilaria Dutto Angela Bachi Alexander Rapp Tiziana Nardo A Ivana Scovassi Daniela Necchi M Cristina Cardoso Lucia A Stivala Ennio Prosperi

Nucleic Acids Res 2014 Jul 17;42(13):8433-48. Epub 2014 Jun 17.

Institute of Molecular Genetics, National Research Council (CNR), Pavia 27100, Italy

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July 2014

Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack.

Authors:
Valentyn Oksenych Alexander Zhovmer Salim Ziani Pierre-Olivier Mari Jitka Eberova Tiziana Nardo Miria Stefanini Giuseppina Giglia-Mari Jean-Marc Egly Frédéric Coin

PLoS Genet 2013 4;9(7):e1003611. Epub 2013 Jul 4.

IGBMC, Department of Functional Genomics and Cancer, CNRS/INSERM/Université de Strasbourg, C. U. Strasbourg, France.

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January 2014

Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia.

Authors:
Kazuya Kashiyama Yuka Nakazawa Daniela T Pilz Chaowan Guo Mayuko Shimada Kensaku Sasaki Heather Fawcett Jonathan F Wing Susan O Lewin Lucinda Carr Tao-Sheng Li Koh-ichiro Yoshiura Atsushi Utani Akiyoshi Hirano Shunichi Yamashita Danielle Greenblatt Tiziana Nardo Miria Stefanini David McGibbon Robert Sarkany Hiva Fassihi Yoshito Takahashi Yuji Nagayama Norisato Mitsutake Alan R Lehmann Tomoo Ogi

Am J Hum Genet 2013 May 25;92(5):807-19. Epub 2013 Apr 25.

Department of Plastic and Reconstructive Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

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May 2013

From laboratory tests to functional characterisation of Cockayne syndrome.

Authors:
Manuela Lanzafame Bruno Vaz Tiziana Nardo Elena Botta Donata Orioli Miria Stefanini

Mech Ageing Dev 2013 May-Jun;134(5-6):171-9. Epub 2013 Apr 6.

Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche, Via Abbiategrasso 207, 27100 Pavia, Italy.

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December 2013

Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.

Authors:
Fortunata Vasaturo Fabiana Solai Carolina Malacrino Tiziana Nardo Bruno Vincenzi Mauro Modesti Susanna Scarpa

Oncol Lett 2013 Jan 17;5(1):316-320. Epub 2012 Oct 17.

Departments of Emergency.

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January 2013

Novel XPG (ERCC5) mutations affect DNA repair and cell survival after ultraviolet but not oxidative stress.

Authors:
Daniela T Soltys Clarissa R R Rocha Letícia K Lerner Tiago A de Souza Veridiana Munford Fernanda Cabral Tiziana Nardo Miria Stefanini Alain Sarasin Januário B Cabral-Neto Carlos F M Menck

Hum Mutat 2013 Mar 17;34(3):481-9. Epub 2013 Jan 17.

Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.

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March 2013

XPD mutations in trichothiodystrophy hamper collagen VI expression and reveal a role of TFIIH in transcription derepression.

Authors:
Donata Orioli Emmanuel Compe Tiziana Nardo Manuela Mura Christophe Giraudon Elena Botta Laura Arrigoni Fiorenzo A Peverali Jean Marc Egly Miria Stefanini

Hum Mol Genet 2013 Mar 5;22(6):1061-73. Epub 2012 Dec 5.

Istituto di Genetica Molecolare CNR, Pavia 27100, Italy.

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March 2013

Oxidized low-density lipoproteins impair endothelial function by inhibiting non-genomic action of thyroid hormone-mediated nitric oxide production in human endothelial cells.

Authors:
Roberto Vicinanza Giuseppe Coppotelli Carolina Malacrino Tiziana Nardo Barbara Buchetti Luisa Lenti Francesco S Celi Susanna Scarpa

Thyroid 2013 Feb;23(2):231-8

Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

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February 2013

p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG.

Authors:
Micol Tillhon Ornella Cazzalini Tiziana Nardo Daniela Necchi Sabrina Sommatis Lucia A Stivala A Ivana Scovassi Ennio Prosperi

DNA Repair (Amst) 2012 Oct 3;11(10):844-52. Epub 2012 Sep 3.

Istituto di Genetica Molecolare (IGM) del CNR, Pavia, Italy.

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October 2012

Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair.

Authors:
Yuka Nakazawa Kensaku Sasaki Norisato Mitsutake Michiko Matsuse Mayuko Shimada Tiziana Nardo Yoshito Takahashi Kaname Ohyama Kosei Ito Hiroyuki Mishima Masayo Nomura Akira Kinoshita Shinji Ono Katsuya Takenaka Ritsuko Masuyama Takashi Kudo Hanoch Slor Atsushi Utani Satoshi Tateishi Shunichi Yamashita Miria Stefanini Alan R Lehmann Koh-ichiro Yoshiura Tomoo Ogi

Nat Genet 2012 May;44(5):586-92

Nagasaki University Research Centre for Genomic Instability and Carcinogenesis, Nagasaki, Japan.

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May 2012

Electrochemotherapy in the treatment of Kaposi sarcoma cutaneous lesions: a two-center prospective phase II trial.

Authors:
Pietro Curatolo Pietro Quaglino Federica Marenco Monica Mancini Tiziana Nardò Claudio Mortera Roberta Rotunno Stefano Calvieri Maria Grazia Bernengo

Ann Surg Oncol 2012 Jan 6;19(1):192-8. Epub 2011 Aug 6.

Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome La Sapienza, Rome, Italy.

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January 2012

FoxP3 expression on melanoma cells is related to early visceral spreading in melanoma patients treated by electrochemotherapy.

Authors:
Pietro Quaglino Simona Osella-Abate Federica Marenco Tiziana Nardò Chiara Gado Mauro Novelli Paola Savoia Maria Grazia Bernengo

Pigment Cell Melanoma Res 2011 Aug 2;24(4):734-6. Epub 2011 Aug 2.

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August 2011

Effectiveness of electrochemotherapy in treatment of a recurrent squamous cell carcinoma of the scalp.

Authors:
Federica Marenco Tiziana Nardò Paola Savoia Maria Grazia Bernengo

Eur J Dermatol 2011 Jul-Aug;21(4):618-9

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December 2011

Melanoma of unknown primary site: a 33-year experience at the Turin Melanoma Centre.

Authors:
Paola Savoia Paolo Fava Simona Osella-Abate Tiziana Nardò Alessandra Comessatti Pietro Quaglino Maria Grazia Bernengo

Melanoma Res 2010 Jun;20(3):227-32

Department of Biomedical Sciences and Human Oncology, Section of Clinics and Oncological Dermatology, University of Turin, Italy.

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June 2010

Skin metastases of malignant melanoma: a clinical and prognostic survey.

Authors:
Paola Savoia Paolo Fava Tiziana Nardò Simona Osella-Abate Pietro Quaglino Maria Grazia Bernengo

Melanoma Res 2009 Oct;19(5):321-6

Department of Biomedical Sciences and Human Oncology, Section of Clinics and Oncological Dermatology, University of Turin, Italy.

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October 2009

A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage.

Authors:
Tiziana Nardo Roberta Oneda Graciela Spivak Bruno Vaz Laurent Mortier Pierre Thomas Donata Orioli Vincent Laugel Anne Stary Philip C Hanawalt Alain Sarasin Miria Stefanini

Proc Natl Acad Sci U S A 2009 Apr 27;106(15):6209-14. Epub 2009 Mar 27.

Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche, via Abbiategrasso 207, 27100 Pavia, Italy.

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April 2009

Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.

Authors:
Monica Savio Tania Coppa Ornella Cazzalini Paola Perucca Daniela Necchi Tiziana Nardo Lucia A Stivala Ennio Prosperi

DNA Repair (Amst) 2009 Jul 24;8(7):778-85. Epub 2009 Mar 24.

Dipartimento di Medicina Sperimentale, sez. Patologia Generale C. Golgi, Università di Pavia, Pavia, Italy.

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July 2009

Genotype-phenotype relationships in trichothiodystrophy patients with novel splicing mutations in the XPD gene.

Authors:
Elena Botta Tiziana Nardo Donata Orioli Roberta Guglielmino Roberta Ricotti Sergio Bondanza Francesco Benedicenti Giovanna Zambruno Miria Stefanini

Hum Mutat 2009 Mar;30(3):438-45

Istituto di Genetica Molecolare Consiglio Nazionale delle Ricerche, Pavia, Italy.

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March 2009

Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy.

Authors:
Wim J Kleijer Vincent Laugel Mark Berneburg Tiziana Nardo Heather Fawcett Alexei Gratchev Nicolaas G J Jaspers Alain Sarasin Miria Stefanini Alan R Lehmann

DNA Repair (Amst) 2008 May 10;7(5):744-50. Epub 2008 Mar 10.

Department of Clinical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands.

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May 2008

Prognostic relevance of baseline and sequential peripheral blood tyrosinase expression in 200 consecutive advanced metastatic melanoma patients.

Authors:
Pietro Quaglino Simona Osella-Abate Nazario Cappello Michela Ortoncelli Tiziana Nardò Maria Teresa Fierro Franco Cavallo Paola Savoia Maria Grazia Bernengo

Melanoma Res 2007 Apr;17(2):75-82

Department of Biomedical Sciences and Human Oncology, Section of Dermatologic Oncology, University of Turin, Turin, Italy.

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April 2007