Tingting Pan

Tingting Pan

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Tingting Pan

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Metformin ameliorates endotoxemia-induced endothelial pro-inflammatory responses via AMPK-dependent mediation of HDAC5 and KLF2.

Biochim Biophys Acta Mol Basis Dis 2019 Jun 16;1865(6):1701-1712. Epub 2019 Apr 16.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439193012
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http://dx.doi.org/10.1016/j.bbadis.2019.04.009DOI Listing
June 2019

PGE signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia.

Proc Natl Acad Sci U S A 2019 May 29;116(20):10019-10024. Epub 2019 Apr 29.

Department of Neurology & Neurological Sciences, Stanford University School of Medicine, Stanford University, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1818544116DOI Listing
May 2019

LBX2-AS1 is activated by ZEB1 and promotes the development of esophageal squamous cell carcinoma by interacting with HNRNPC to enhance the stability of ZEB1 and ZEB2 mRNAs.

Biochem Biophys Res Commun 2019 Apr 26;511(3):566-572. Epub 2019 Feb 26.

Department of Thoracic Surgery, Tumor Hospital of Wuwei, Wuwei, Gansu, 733000, China.

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http://dx.doi.org/10.1016/j.bbrc.2019.02.079DOI Listing
April 2019

LINC00473/miR-374a-5p regulates esophageal squamous cell carcinoma via targeting SPIN1 to weaken the effect of radiotherapy.

J Cell Biochem 2019 Apr 24. Epub 2019 Apr 24.

Department of Thoracic Surgery, Tumor Hospital of Wuwei, Wuwei, Gansu, China.

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http://dx.doi.org/10.1002/jcb.28717DOI Listing
April 2019

High-throughput extracellular pH monitoring and antibiotics screening by polymeric fluorescent sensor with LCST property.

Methods 2019 Apr 30. Epub 2019 Apr 30.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa, Macau, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2019.04.017DOI Listing
April 2019

Facile fabrication of Shewanella@graphene core-shell material and its enhanced performance in nitrobenzene reduction.

Sci Total Environ 2019 Mar 5;658:324-332. Epub 2018 Dec 5.

Department of Environmental Science, Zhejiang University, Hangzhou 310058, China; Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Hangzhou 310058, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00489697183486
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http://dx.doi.org/10.1016/j.scitotenv.2018.12.028DOI Listing
March 2019

Circulating Heme Oxygenase-1 and Complement Activation in Transplant-Associated Thrombotic Microangiopathy.

Biol Blood Marrow Transplant 2019 Mar 12. Epub 2019 Mar 12.

The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou, China; Collaborative Innovation Center of Hematology, Suzhou, China; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China; Institute of Blood and Marrow Transplantation, Suzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.03.002DOI Listing
March 2019

Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.

Eur J Med Chem 2019 Feb 7;163:512-526. Epub 2018 Dec 7.

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.12.013DOI Listing
February 2019

Design, Synthesis, and Biological Evaluation of Dual-Target Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 9A (PDE9A) for the Treatment of Alzheimer's Disease.

ACS Chem Neurosci 2019 Jan 12;10(1):537-551. Epub 2018 Oct 12.

School of Pharmaceutical Sciences , Sun Yat-sen University , Guangzhou 510006 , China.

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http://dx.doi.org/10.1021/acschemneuro.8b00376DOI Listing
January 2019

Preparation and application of ratiometric polystyrene-based microspheres as oxygen sensors.

Anal Chim Acta 2018 Nov 5;1030:194-201. Epub 2018 May 5.

Department of Materials Science and Engineering, Southern University of Science and Technology, No. 1088, Xueyuan Rd., Xili, Nanshan District, Shenzhen, Guangdong, 518055, China. Electronic address:

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https://www.sciencedirect.com/journal/analytica-chimica-acta
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https://linkinghub.elsevier.com/retrieve/pii/S00032670183060
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http://dx.doi.org/10.1016/j.aca.2018.05.017DOI Listing
November 2018

Design, synthesis, and biological evaluation of histone deacetylase inhibitors possessing glutathione peroxidase-like and antioxidant activities against Alzheimer's disease.

Bioorg Med Chem 2018 Nov 24;26(21):5718-5729. Epub 2018 Oct 24.

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

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http://dx.doi.org/10.1016/j.bmc.2018.10.022DOI Listing
November 2018

Efficacy and safety of recombinant human parathyroid hormone (1-34) are similar to those of alendronate in the treatment of postmenopausal osteoporosis.

Medicine (Baltimore) 2018 Nov;97(47):e13341

Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1097/MD.0000000000013341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392772PMC
November 2018

Next-generation sequencing of the BALF in the diagnosis of community-acquired pneumonia in immunocompromised patients.

J Infect 2018 Nov 23. Epub 2018 Nov 23.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Rui-Jin Er Rd, Shanghai 200025, China. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2018.11.005DOI Listing
November 2018

Discovery of boron-containing compounds as Aβ aggregation inhibitors and antioxidants for the treatment of Alzheimer's disease.

Medchemcomm 2018 Nov 12;9(11):1862-1870. Epub 2018 Sep 12.

Institute of Drug Synthesis and Pharmaceutical Process , School of Pharmaceutical Sciences , Sun Yat-sen University , Guangzhou 510006 , China . Email: ; ; Tel: +086 20 3994 3051.

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http://dx.doi.org/10.1039/c8md00315gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254047PMC
November 2018

Addition of histone deacetylase inhibitors does not improve prognosis in patients with myelodysplastic syndrome and acute myeloid leukemia compared with hypomethylating agents alone: A systematic review and meta-analysis of seven prospective cohort studies.

Leuk Res 2018 08 9;71:13-24. Epub 2018 Jun 9.

Cyrus Tang Hematology Center, Soochow University, Suzhou, China; The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou, China; Collaborative Innovation Center of Hematology, Suzhou, China; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.06.007DOI Listing
August 2018

The design, synthesis and evaluation of selenium-containing 4-anilinoquinazoline hybrids as anticancer agents and a study of their mechanism.

Org Biomol Chem 2018 07 14;16(25):4701-4714. Epub 2018 Jun 14.

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

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http://dx.doi.org/10.1039/c8ob00875bDOI Listing
July 2018

JMJD3 is involved in neutrophil membrane proteinase 3 overexpression during the hyperinflammatory response in early sepsis.

Int Immunopharmacol 2018 Jun 3;59:40-46. Epub 2018 Apr 3.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui-Jin Er Road, Shanghai 200025, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2018.03.027DOI Listing
June 2018

Transcriptomic Analysis on Responses of Murine Lungs to Infection.

Front Cell Infect Microbiol 2017 20;7:251. Epub 2017 Jun 20.

College of Animal Science and Technology, Southwest UniversityChongqing, China.

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http://dx.doi.org/10.3389/fcimb.2017.00251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476747PMC
February 2018

Terahertz spectroscopic investigation of gallic acid and its monohydrate.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Feb 4;190:40-46. Epub 2017 Sep 4.

Division of Interfacial Water and Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China. Electronic address:

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http://dx.doi.org/10.1016/j.saa.2017.09.004DOI Listing
February 2018

Multifunctional PHPMA-Derived Polymer for Ratiometric pH Sensing, Fluorescence Imaging, and Magnetic Resonance Imaging.

ACS Appl Mater Interfaces 2018 Jan 5;10(2):1556-1565. Epub 2018 Jan 5.

Department of Materials Science and Engineering, Southern University of Science and Technology , Shenzhen, Guangdong 518055, China.

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http://dx.doi.org/10.1021/acsami.7b15796DOI Listing
January 2018

Efficacy of recombinant factor VIIa for severe bleeding complicated by platelet transfusion refractoriness in patients with hematologic malignancies.

Thromb Res 2017 Dec 19;160:14-18. Epub 2017 Oct 19.

Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China; Collaborative Innovation Center of Hematology of Soochow University, Suzhou, China; Institute of Blood and Marrow Transplantation, Suzhou, China; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2017.10.015DOI Listing
December 2017

Downregulation of hypoxia-inducible factor-1α contributes to impaired megakaryopoiesis in immune thrombocytopenia.

Thromb Haemost 2017 10 3;117(10):1875-1886. Epub 2017 Aug 3.

Yue Han, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Haematology, 188 Shizi Street, Suzhou, Jiangsu province, 215006 P.R. China, Tel.: +86 13901551669, E-mail: or, Li Zhu, Cyrus Tang Hematology Center, Soochow University, Rm 509, Bldg 703, 199 Ren'ai Road, Suzhou, Jiangsu, 215123 P.R. China, Tel.: +86 0512 65880899 ext. 3509, E-mail:

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH17-03-0155
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http://dx.doi.org/10.1160/TH17-03-0155DOI Listing
October 2017

Luminescence materials for pH and oxygen sensing in microbial cells - structures, optical properties, and biological applications.

Crit Rev Biotechnol 2017 Sep 15;37(6):723-738. Epub 2016 Sep 15.

b Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology , Tianjin University , Tianjin , P.R. China.

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http://dx.doi.org/10.1080/07388551.2016.1223011DOI Listing
September 2017

IL17-Producing γδ T Cells May Enhance Humoral Immunity during Pulmonary Infection in Mice.

Front Cell Infect Microbiol 2016 6;6:170. Epub 2016 Dec 6.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine Shanghai, China.

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http://dx.doi.org/10.3389/fcimb.2016.00170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138229PMC
September 2017

Monocyte programmed death ligand-1 expression is an early marker for predicting infectious complications in acute pancreatitis.

Crit Care 2017 Jul 14;21(1):186. Epub 2017 Jul 14.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Rui-Jin Er Road, Shanghai, 200025, China.

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http://dx.doi.org/10.1186/s13054-017-1781-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513119PMC
July 2017

Chemical Synthesis of the ODM-201's Diastereomers through an Efficient Intramolecular 1,3-Dipolar Cycloaddition.

Chem Pharm Bull (Tokyo) 2017 Jun 5;65(6):582-585. Epub 2017 Apr 5.

State Key Lab of New Drug & Pharmaceutical Process, State Institute of Pharmaceutical Industry.

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http://dx.doi.org/10.1248/cpb.c17-00176DOI Listing
June 2017

Terahertz spectra of l-phenylalanine and its monohydrate.

Spectrochim Acta A Mol Biomol Spectrosc 2017 May 26;178:19-23. Epub 2017 Jan 26.

Division of Interfacial Water and Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China. Electronic address:

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http://dx.doi.org/10.1016/j.saa.2017.01.050DOI Listing
May 2017

Improved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion technique.

Int J Nanomedicine 2016 5;11:3777-88. Epub 2016 Aug 5.

Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, People's Republic of China.

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http://dx.doi.org/10.2147/IJN.S105419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981171PMC
February 2017

Unexpectedly Enhanced Solubility of Aromatic Amino Acids and Peptides in an Aqueous Solution of Divalent Transition-Metal Cations.

Phys Rev Lett 2016 Dec 2;117(23):238102. Epub 2016 Dec 2.

Division of Interfacial Water and Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.

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http://dx.doi.org/10.1103/PhysRevLett.117.238102DOI Listing
December 2016

Comparative Genomics Analysis of Two Different Virulent Bovine Isolates.

Int J Genomics 2016 14;2016:4512493. Epub 2016 Dec 14.

The State Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400716, China.

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https://www.hindawi.com/journals/ijg/2016/4512493/
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http://dx.doi.org/10.1155/2016/4512493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192330PMC
December 2016

Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator.

J Virol 2016 Nov 14;90(21):9953-9966. Epub 2016 Oct 14.

Key Laboratory of Medical Molecular Virology and Department of Medical Microbiology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China

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http://dx.doi.org/10.1128/JVI.01140-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068543PMC
November 2016

Hepatitis C virus replicative double-stranded RNA is a potent interferon inducer that triggers interferon production through MDA5.

J Gen Virol 2016 Nov 16;97(11):2868-2882. Epub 2016 Sep 16.

2​Institute of Biomedical Sciences, Fudan University, Shanghai, PR China 1​Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, PR China 3​Institute of Medical Microbiology, Fudan University, Shanghai, PR China.

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http://www.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/jgv.0.000607DOI Listing
November 2016

A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis.

Oncotarget 2016 Sep;7(36):57705-57713

Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Hefei 230001, China.

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http://dx.doi.org/10.18632/oncotarget.9531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295383PMC
September 2016

Notch Signaling Pathway Was Involved in Regulating Programmed Cell Death 1 Expression during Sepsis-Induced Immunosuppression.

Mediators Inflamm 2015 30;2015:539841. Epub 2015 Apr 30.

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Rui-Jin Er Road, Shanghai 200025, China.

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http://www.hindawi.com/journals/mi/2015/539841/
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http://dx.doi.org/10.1155/2015/539841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430661PMC
February 2016

Expression and clinical significance of Nectin-4 in hepatocellular carcinoma.

Onco Targets Ther 2016 6;9:183-90. Epub 2016 Jan 6.

Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Affiliated Provincial Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China; Department of Hepatic Surgery, Affiliated Provincial Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S96999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708195PMC
January 2016

Young Chinese children's beliefs about the implications of subtypes of social withdrawal: A first look at social avoidance.

Br J Dev Psychol 2015 Jun 24;33(2):159-73. Epub 2015 Jan 24.

Shanghai Key Laboratory of Brain Functional Genomics, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China.

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http://dx.doi.org/10.1111/bjdp.12081DOI Listing
June 2015

Starting small: Revisiting young children's perceptions of social withdrawal in China.

Br J Dev Psychol 2015 Jun 15;33(2):183-6. Epub 2015 Apr 15.

Shanghai Key Laboratory of Brain Functional Genomics, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China.

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http://dx.doi.org/10.1111/bjdp.12089DOI Listing
June 2015

Theoretical screening of novel alkyne bridged zinc porphyrins as sensitizer candidates for dye-sensitized solar cells.

Spectrochim Acta A Mol Biomol Spectrosc 2014 Dec 14;133:514-20. Epub 2014 Jun 14.

Division of Solar Energy Materials and Engineering, Institute of Plasma Physics, Chinese Academy of Sciences, P.O. Box 1126, Hefei, Anhui 230031, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.saa.2014.06.015DOI Listing
December 2014

Digital PCR on an integrated self-priming compartmentalization chip.

Lab Chip 2014 Mar;14(6):1176-85

Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou, PR China.

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http://dx.doi.org/10.1039/c3lc51327kDOI Listing
March 2014

Theoretical design and screening of alkyne bridged triphenyl zinc porphyrins as sensitizer candidates for dye-sensitized solar cells.

Spectrochim Acta A Mol Biomol Spectrosc 2014 Jan 12;118:564-71. Epub 2013 Sep 12.

Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13861425130102
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http://dx.doi.org/10.1016/j.saa.2013.09.020DOI Listing
January 2014

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.

Nat Immunol 2013 Aug 7;14(8):793-803. Epub 2013 Jul 7.

Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.

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http://www.mvlabyzh.fudan.edu.cn/admin/pic/uploadfile/201307
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http://search.proquest.com/openview/d61719774f7912ab064e7206
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http://dx.doi.org/10.1038/ni.2647DOI Listing
August 2013

Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33.

J Gen Virol 2012 Jan 28;93(Pt 1):83-92. Epub 2011 Sep 28.

Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, PR China.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.033860-0DOI Listing
January 2012

Signaling via the prostaglandin E₂ receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia.

J Clin Invest 2011 Nov 3;121(11):4362-71. Epub 2011 Oct 3.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.

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http://www.jci.org/articles/view/46279
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http://dx.doi.org/10.1172/JCI46279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204834PMC
November 2011

Subproteomic study of hepatitis C virus replicon reveals Ras-GTPase-activating protein binding protein 1 as potential HCV RC component.

Biochem Biophys Res Commun 2006 Nov 18;350(1):174-8. Epub 2006 Sep 18.

Key Laboratory of Medical Molecular Virology, Institute of Medical Microbiology, Shanghai Medical College, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1016/j.bbrc.2006.09.027DOI Listing
November 2006

Subproteomic analysis of the cellular proteins associated with the 3' untranslated region of the hepatitis C virus genome in human liver cells.

Biochem Biophys Res Commun 2006 Sep 5;347(3):683-91. Epub 2006 Jul 5.

Key Laboratory of Medical Molecular Virology, Shanghai Medical College, Fudan University, China.

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http://dx.doi.org/10.1016/j.bbrc.2006.06.144DOI Listing
September 2006

Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.

FEBS Lett 2006 Aug 17;580(18):4392-400. Epub 2006 Jul 17.

Key Laboratory of Medical Molecular Virology, Shanghai Medical College, Institutes of Medical Microbiology and Biomedical Sciences, Fudan University, P.O. Box 228, 138 Yi Xue Yuan Road, Shanghai 200032, PR China.

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http://doi.wiley.com/10.1016/j.febslet.2006.07.002
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http://dx.doi.org/10.1016/j.febslet.2006.07.002DOI Listing
August 2006