Tina L Yuan

Tina L Yuan

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Tina L Yuan

Tina L Yuan

Publications by authors named "Tina L Yuan"

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13Publications

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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.

Cell Rep 2019 Oct;29(1):118-134.e8

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, MA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.090DOI Listing
October 2019

MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival.

Proc Natl Acad Sci U S A 2019 Mar 1;116(10):4508-4517. Epub 2019 Feb 1.

Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1817494116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410784PMC
March 2019

Differential Effector Engagement by Oncogenic KRAS.

Cell Rep 2018 02;22(7):1889-1902

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1450 3rd Street, San Francisco, CA 94158, USA; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., P.O. Box B, Frederick, MD 21702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343826PMC
February 2018

Killing tumors by keeping ras and PI3' kinase apart.

Cancer Cell 2013 Nov;24(5):562-3

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.ccr.2013.10.015DOI Listing
November 2013

Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations.

Curr Biol 2011 Feb 20;21(3):173-83. Epub 2011 Jan 20.

Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cub.2010.12.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394538PMC
February 2011

Introduction.

Curr Top Microbiol Immunol 2010 ;346:1-7

Department of Systems Biology and Beth Israel Deaconess Medical Center, Division of Signal Transduction, Harvard University, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/82_2010_55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394431PMC
January 2011

E2F4 cooperates with pRB in the development of extra-embryonic tissues.

Dev Biol 2009 Aug 9;332(1):104-15. Epub 2009 May 9.

David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.ydbio.2009.05.541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832217PMC
August 2009

The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development.

Mol Cancer Res 2008 Sep;6(9):1440-51

David H. Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-08
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697052PMC
September 2008

Class 1A PI3K regulates vessel integrity during development and tumorigenesis.

Proc Natl Acad Sci U S A 2008 Jul 10;105(28):9739-44. Epub 2008 Jul 10.

Departments of Systems Biology and Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0804123105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453070PMC
July 2008

Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues.

Mol Cell Biol 2007 Mar 8;27(6):2283-93. Epub 2007 Jan 8.

Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1128/MCB.01854-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820513PMC
March 2007

The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity.

Proc Natl Acad Sci U S A 2003 Mar 25;100(5):2456-61. Epub 2003 Feb 25.

Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.0138064100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151362PMC
March 2003