Publications by authors named "Timothy Wiltshire"

12Publications

Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice.

Neuroreport 2017 Dec;28(18):1215-1220

aDepartment of Anesthesiology, Perioperative Medicine and Pain Management bJohn P. Hussman Institute for Human Genomics cJohn T. Macdonald Foundation, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida dCenter for Pharmacogenetics and Individualized Therapy, University of North Caroline, Eshelman School of Pharmacy, Chapel Hill eDepartment of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/WNR.0000000000000872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685868PMC
December 2017

Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex.

J Biol Chem 2012 Jan 2;287(4):2854-62. Epub 2011 Dec 2.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1074/jbc.M111.307868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268443PMC
January 2012

Toxicogenetics: population-based testing of drug and chemical safety in mouse models.

Pharmacogenomics 2010 Aug;11(8):1127-36

Department of Environmental Sciences & Engineering, 0031 Michael Hooker Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.2217/pgs.10.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035927PMC
August 2010

Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.

J Biol Chem 2010 May 15;285(19):14565-71. Epub 2010 Mar 15.

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1074/jbc.M110.104745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863164PMC
May 2010

BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven.

Mol Pharmacol 2007 Apr 17;71(4):1051-60. Epub 2007 Jan 17.

Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506-9300, USA.

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http://dx.doi.org/10.1124/mol.106.029504DOI Listing
April 2007

Fanconi anemia D2 protein confers chemoresistance in response to the anticancer agent, irofulven.

Mol Cancer Ther 2006 Dec;5(12):3153-61

Mary Babb Randolph Cancer Center, West Virginia University, 1835 Health Sciences South, P.O. Box 9300, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0427DOI Listing
December 2006

Irofulven induces replication-dependent CHK2 activation related to p53 status.

Biochem Pharmacol 2007 Feb 27;73(4):469-80. Epub 2006 Oct 27.

Mary Babb Randolph Cancer Center, West Virginia University School of Medicine, Morgantown, WV 26506, United States.

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http://dx.doi.org/10.1016/j.bcp.2006.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800887PMC
February 2007

ATM-dependent CHK2 activation induced by anticancer agent, irofulven.

J Biol Chem 2004 Sep 20;279(38):39584-92. Epub 2004 Jul 20.

Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia 26506, USA.

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http://dx.doi.org/10.1074/jbc.M400015200DOI Listing
September 2004