Publications by authors named "Timothy Semple"

33Publications

Improved next-generation sequencing pre-capture library yields and sequencing parameters using on-bead PCR.

Biotechniques 2020 01 11;68(1):48-51. Epub 2019 Dec 11.

Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.

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http://dx.doi.org/10.2144/btn-2019-0059DOI Listing
January 2020

A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens.

Methods Mol Biol 2018 ;1725:201-227

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7568-6_17DOI Listing
January 2019

Whole-genome characterization of chemoresistant ovarian cancer.

Nature 2015 May;521(7553):489-94

1] Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia [2] Department of Pathology, University of Melbourne, Parkville, Victoria 3052, Australia [3] Sir Peter MacCallum Cancer Centre Department of Oncology, University of Melbourne, Parkville, Victoria 3052, Australia [4] Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London W12 0HS, UK [5] Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1038/nature14410DOI Listing
May 2015

Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary.

J Pathol 2013 Dec;231(4):413-23

The Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia; The Department of Pathology, University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1002/path.4251DOI Listing
December 2013

Waiting in pain.

Med J Aust 2012 Apr;196(6):372-3

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http://dx.doi.org/10.5694/mja12.10148DOI Listing
April 2012

The Th17-defining transcription factor RORγt promotes glomerulonephritis.

J Am Soc Nephrol 2011 Mar 23;22(3):472-83. Epub 2010 Dec 23.

Centre for Inflammatory Diseases, Monash University Department of Medicine, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1681/ASN.2010040435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060441PMC
March 2011

Th1 and Th17 cells induce proliferative glomerulonephritis.

J Am Soc Nephrol 2009 Dec 9;20(12):2518-24. Epub 2009 Oct 9.

Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1681/ASN.2009030337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794236PMC
December 2009

IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis.

Nephrol Dial Transplant 2009 Oct 22;24(10):3024-32. Epub 2009 May 22.

Department of Medicine, Centre for Inflammatory Diseases, Monash University, Monash Medical Centre, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1093/ndt/gfp214DOI Listing
October 2009

T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis.

J Am Soc Nephrol 2008 Mar 30;19(3):477-85. Epub 2008 Jan 30.

Department of Medicine, Monash University, Monash Medical Centre, Level 5 Block E, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1681/ASN.2007030392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391047PMC
March 2008

Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis.

J Am Soc Nephrol 2007 Mar 31;18(3):760-70. Epub 2007 Jan 31.

Centre for Inflammatory Diseases, Monash University, Department of Medicine, Monash Medical Centre, Level 5 Block E, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1681/ASN.2006040375DOI Listing
March 2007

CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis.

J Immunol 2006 Sep;177(5):3406-12

Centre for Inflammatory Diseases, Monash University Department of Medicine, Clayton, Victoria, Australia.

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http://dx.doi.org/10.4049/jimmunol.177.5.3406DOI Listing
September 2006

Inducible co-stimulatory molecule ligand is protective during the induction and effector phases of crescentic glomerulonephritis.

J Am Soc Nephrol 2006 Apr 15;17(4):1044-53. Epub 2006 Mar 15.

Department of Medicine, Monash University, Monash Medical Centre, Level 5 Block E, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://jasn.asnjournals.org/content/early/2006/03/15/ASN.200
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http://www.jasn.org/cgi/doi/10.1681/ASN.2005101022
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http://dx.doi.org/10.1681/ASN.2005101022DOI Listing
April 2006

A pathogenetic role for mast cells in experimental crescentic glomerulonephritis.

J Am Soc Nephrol 2006 Jan 30;17(1):150-9. Epub 2005 Nov 30.

Center for Inflammatory Diseases, Monash University, Department of Medicine, Monash Medical Center, 246 Clayton Road, Melbourne, Victoria 3168, Australia.

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http://dx.doi.org/10.1681/ASN.2005080799DOI Listing
January 2006

Granulocyte macrophage colony-stimulating factor expression by both renal parenchymal and immune cells mediates murine crescentic glomerulonephritis.

J Am Soc Nephrol 2005 Sep 20;16(9):2646-56. Epub 2005 Jul 20.

Centre for Inflammatory Diseases, Monash University, Department of Medicine, Monash Medical Center, Clayton, 3168 Victoria, Australia.

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http://jasn.asnjournals.org/content/16/9/2646.full.pdf
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http://www.jasn.org/cgi/doi/10.1681/ASN.2004121107
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http://dx.doi.org/10.1681/ASN.2004121107DOI Listing
September 2005

Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis.

J Am Soc Nephrol 2005 Jul 8;16(7):2012-22. Epub 2005 Jun 8.

Monash University, Department of Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2004060437
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http://dx.doi.org/10.1681/ASN.2004060437DOI Listing
July 2005

IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment.

J Am Soc Nephrol 2005 Jul 11;16(7):2023-33. Epub 2005 May 11.

Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1681/ASN.2004121075DOI Listing
July 2005

Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: a protective role for IFN-gamma.

J Am Soc Nephrol 2004 Jul;15(7):1764-74

Centre for Inflammatory Diseases, Monash University, Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1097/01.asn.0000128968.27705.5eDOI Listing
July 2004

An IL-12-independent role for CD40-CD154 in mediating effector responses: studies in cell-mediated glomerulonephritis and dermal delayed-type hypersensitivity.

J Immunol 2004 Jul;173(1):136-44

Centre for Inflammatory Diseases, Department of Medicine, Monash University, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.4049/jimmunol.173.1.136DOI Listing
July 2004

Intrinsic renal cell expression of CD40 directs Th1 effectors inducing experimental crescentic glomerulonephritis.

J Am Soc Nephrol 2003 Nov;14(11):2813-22

Centre for Inflammatory Diseases, Monash University, Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1097/01.asn.0000091381.60059.fbDOI Listing
November 2003