Publications by authors named "Timothy S Blackwell"

100Publications

Perfusion and Inflation of the Mouse Lung for Tumor Histology.

J Vis Exp 2020 08 6(162). Epub 2020 Aug 6.

Department of Genetics, University of Alabama at Birmingham;

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http://dx.doi.org/10.3791/60605DOI Listing
August 2020

Phosphorylation of PLCγ1 by EphA2 Receptor Tyrosine Kinase Promotes Tumor Growth in Lung Cancer.

Mol Cancer Res 2020 Nov 4;18(11):1735-1743. Epub 2020 Aug 4.

Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1158/1541-7786.MCR-20-0075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641970PMC
November 2020

Enhanced Expression of Catalase in Mitochondria Modulates NF-κB-Dependent Lung Inflammation through Alteration of Metabolic Activity in Macrophages.

J Immunol 2020 Aug 29;205(4):1125-1134. Epub 2020 Jun 29.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232;

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http://dx.doi.org/10.4049/jimmunol.1900820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415609PMC
August 2020

Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis.

Oncotarget 2019 Dec 17;10(66):7031-7042. Epub 2019 Dec 17.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University, Nashville, TN 37212, USA.

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http://dx.doi.org/10.18632/oncotarget.27345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925028PMC
December 2019

Epithelial Injury and Dysfunction in the Pathogenesis of Idiopathic PulmonaryFibrosis.

Am J Med Sci 2019 05 22;357(5):374-378. Epub 2019 Jan 22.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicineand; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee; Department of Veterans Affairs Medical Center, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.amjms.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481315PMC
May 2019

Progress in Understanding and Treating Idiopathic Pulmonary Fibrosis.

Annu Rev Med 2019 01;70:211-224

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA; email: ,

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http://dx.doi.org/10.1146/annurev-med-041317-102715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378692PMC
January 2019

lncITPF Promotes Pulmonary Fibrosis by Targeting hnRNP-L Depending on Its Host Gene ITGBL1.

Mol Ther 2019 02 6;27(2):380-393. Epub 2018 Sep 6.

Department of Respiratory Medicine, Affiliated Hospital to Binzhou Medical University, Binzhou 256602, China; Department of Cellular and Genetic Medicine, School of Pharmaceutical Sciences, Binzhou Medical University, Yantai 264003, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.08.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369732PMC
February 2019

Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.

JCI Insight 2018 08 23;3(16). Epub 2018 Aug 23.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1172/jci.insight.99543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141182PMC
August 2018

Lung injury and fibrosis induced by a mutant form of surfactant protein C.

J Clin Invest 2018 08 13;128(9):3745-3746. Epub 2018 Aug 13.

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http://dx.doi.org/10.1172/JCI122727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118571PMC
August 2018

Idiopathic pulmonary fibrosis: Epithelial-mesenchymal interactions and emerging therapeutic targets.

Matrix Biol 2018 10 3;71-72:112-127. Epub 2018 Apr 3.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Veterans Affairs Medical Center, Nashville, TN, United States; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146058PMC
October 2018

Endoplasmic reticulum stress in pulmonary fibrosis.

Matrix Biol 2018 08 19;68-69:355-365. Epub 2018 Mar 19.

Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Veterans Affairs Medical Center, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392005PMC
August 2018

NF-κB is weakly activated in the NOD mouse model of type 1 diabetes.

Sci Rep 2018 03 9;8(1):4217. Epub 2018 Mar 9.

Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, Victoria, Australia.

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http://dx.doi.org/10.1038/s41598-018-22738-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844878PMC
March 2018

Salt-bridge modulates differential calcium-mediated ligand binding to integrin α1- and α2-I domains.

Sci Rep 2018 02 13;8(1):2916. Epub 2018 Feb 13.

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232-2372, USA.

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http://dx.doi.org/10.1038/s41598-018-21231-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811549PMC
February 2018

Three-dimensional spatial analysis of missense variants in RTEL1 identifies pathogenic variants in patients with Familial Interstitial Pneumonia.

BMC Bioinformatics 2018 01 23;19(1):18. Epub 2018 Jan 23.

Department of Biological Sciences, Vanderbilt Genetics Institute, and Center for Structural Biology, Vanderbilt University, Nashville, USA.

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http://dx.doi.org/10.1186/s12859-018-2010-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781290PMC
January 2018

Endoplasmic reticulum stress in the pathogenesis of fibrotic disease.

J Clin Invest 2018 01 2;128(1):64-73. Epub 2018 Jan 2.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1172/JCI93560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749533PMC
January 2018

Suppressed ubiquitination of Nrf2 by p47 contributes to Nrf2 activation.

Free Radic Biol Med 2017 12 19;113:48-58. Epub 2017 Sep 19.

Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889093PMC
December 2017

IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis.

Am J Pathol 2017 Dec 18;187(12):2635-2644. Epub 2017 Sep 18.

Department of Pediatrics, University of California, San Diego, La Jolla, California; Rady Children's Hospital, San Diego, San Diego, California. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718091PMC
December 2017

Reply: The Genetic Diagnosis of Interstitial Lung Disease: A Need for an International Consensus.

Am J Respir Crit Care Med 2017 06;195(11):1539-1540

1 Vanderbilt University Medical Center Nashville, Tennessee.

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http://dx.doi.org/10.1164/rccm.201612-2520LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470755PMC
June 2017

Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.

J Clin Invest 2017 Jun 2;127(6):2262-2276. Epub 2017 May 2.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine or Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee USA.

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http://dx.doi.org/10.1172/JCI88629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451236PMC
June 2017

The innate immune response in fetal lung mesenchymal cells targets VEGFR2 expression and activity.

Am J Physiol Lung Cell Mol Physiol 2017 06 23;312(6):L861-L872. Epub 2017 Mar 23.

Department of Pediatrics, University of California, San Diego, and Rady Children's Hospital, San Diego, California; and

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http://dx.doi.org/10.1152/ajplung.00554.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495951PMC
June 2017

Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome.

JCI Insight 2016 Oct 20;1(17):e88947. Epub 2016 Oct 20.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1172/jci.insight.88947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070955PMC
October 2016

Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment.

Oncoimmunology 2016 Jun 30;5(6):e1168549. Epub 2016 Mar 30.

Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Veterans Affairs Medical Center, Nashville, TN, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1168549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938365PMC
June 2016

Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer.

Cell Rep 2016 06 16;16(1):120-132. Epub 2016 Jun 16.

Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, 691 Preston Building, 2220 Pierce Ave., Nashville, TN 37232, USA; U.S. Department of Veterans Affairs, Washington, DC 20420, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232 USA.

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http://dx.doi.org/10.1016/j.celrep.2016.05.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927403PMC
June 2016

Extracellular chloride signals collagen IV network assembly during basement membrane formation.

J Cell Biol 2016 05;213(4):479-94

Department of Biochemistry, Vanderbilt University Medical Center, Nashville, TN 37232 Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 Center for Matrix Biology, Vanderbilt University Medical Center, Nashville, TN 37232 Aspirnaut Program, Vanderbilt University Medical Center, Nashville, TN 37232 Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232 Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232 Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232 Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical Center, Nashville, TN 37232

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http://dx.doi.org/10.1083/jcb.201510065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878091PMC
May 2016

Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development.

Am J Pathol 2016 07 12;186(7):1786-1800. Epub 2016 May 12.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee; Nashville Veterans Affairs Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1016/j.ajpath.2016.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929391PMC
July 2016

Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency.

Nat Commun 2016 Apr 5;7:11240. Epub 2016 Apr 5.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, T-1218 MCN, Nashville, Tennessee 37232-2650, USA.

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http://dx.doi.org/10.1038/ncomms11240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822073PMC
April 2016

IL-1β and Inflammasome Activity Link Inflammation to Abnormal Fetal Airway Development.

J Immunol 2016 Apr 7;196(8):3411-20. Epub 2016 Mar 7.

Department of Pediatrics, University of California, San Diego and Rady Children's Hospital, San Diego, La Jolla, CA 92093;

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http://dx.doi.org/10.4049/jimmunol.1500906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315059PMC
April 2016

p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment.

J Immunol 2016 Feb 15;196(4):1891-9. Epub 2016 Jan 15.

Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University, Nashville, TN 37232; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232; and Department of Veterans Affairs Medical Center, Nashville, TN 37232

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http://www.jimmunol.org/content/early/2016/01/15/jimmunol.15
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1501555
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http://dx.doi.org/10.4049/jimmunol.1501555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744539PMC
February 2016

Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs.

Oncotarget 2016 Feb;7(5):5470-82

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37232 USA.

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http://dx.doi.org/10.18632/oncotarget.6562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868699PMC
February 2016

Personalizing Therapy in Idiopathic Pulmonary Fibrosis: A Glimpse of the Future?

Am J Respir Crit Care Med 2015 Dec;192(12):1409-11

1 Department of Medicine Vanderbilt University School of Medicine Nashville, Tennessee.

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http://dx.doi.org/10.1164/rccm.201509-1789EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731727PMC
December 2015

Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2016 Feb 4;310(3):L249-62. Epub 2015 Dec 4.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee; Department of Veterans Affairs Medical Center, Nashville, Tennessee; and.

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http://dx.doi.org/10.1152/ajplung.00258.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838140PMC
February 2016

Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease.

Virchows Arch 2015 Dec 2;467(6):657-665. Epub 2015 Oct 2.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, School of Medicine, Vanderbilt University, Nashville, TN, 37232-2650, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081073PMC
http://dx.doi.org/10.1007/s00428-015-1854-0DOI Listing
December 2015

Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ.

BMC Cancer 2015 Sep 30;15:647. Epub 2015 Sep 30.

Department of Cancer Biology, Vanderbilt University Medical Center, 23rd Ave S and Pierce PRB 325, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1186/s12885-015-1652-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590702PMC
September 2015

NF-κB-dependent airway inflammation triggers systemic insulin resistance.

Am J Physiol Regul Integr Comp Physiol 2015 Nov 16;309(9):R1144-52. Epub 2015 Sep 16.

Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee;

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http://dx.doi.org/10.1152/ajpregu.00442.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666958PMC
November 2015

The genetic basis of idiopathic pulmonary fibrosis.

Eur Respir J 2015 Jun 2;45(6):1717-27. Epub 2015 Apr 2.

Division of Allergy, Pulmonary and Critical Care Medicine, Dept of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1183/09031936.00163814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849867PMC
June 2015

Chronic obstructive pulmonary disease and subsequent overall and lung cancer mortality in low-income adults.

PLoS One 2015 26;10(3):e0121805. Epub 2015 Mar 26.

Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America; International Epidemiology Institute, Rockville, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121805PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374870PMC
February 2016

Evidence for a novel functional role of astrocytes in the acute homeostatic response to high-fat diet intake in mice.

Mol Metab 2015 Jan 16;4(1):58-63. Epub 2014 Oct 16.

Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 702 Light Hall, 2213 Garland Ave, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.molmet.2014.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314532PMC
January 2015

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

Kidney Int 2015 May 7;87(5):948-62. Epub 2015 Jan 7.

1] Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA [2] Department of Medicine, Veterans Affairs Hospitals, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1038/ki.2014.386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425591PMC
May 2015

Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.

Development 2014 Dec 13;141(24):4751-62. Epub 2014 Nov 13.

Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232, USA Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA Nashville Veterans Affairs Medical Center, Nashville, TN 37232, USA

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http://dx.doi.org/10.1242/dev.117200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299273PMC
December 2014

IκB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm.

J Immunol 2014 Aug 30;193(3):1184-93. Epub 2014 Jun 30.

Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093; Rady Children's Hospital, San Diego, CA 92123;Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232;Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232;Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232; andDepartment of Biostatistics, Vanderbilt University, Nashville, TN 37232

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1302516
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http://dx.doi.org/10.4049/jimmunol.1302516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108541PMC
August 2014

Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.

Infect Immun 2014 Sep 23;82(9):3723-39. Epub 2014 Jun 23.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

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http://iai.asm.org/lookup/doi/10.1128/IAI.00035-14
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http://dx.doi.org/10.1128/IAI.00035-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187810PMC
September 2014

BMP pathway regulation of and by macrophages.

PLoS One 2014 8;9(4):e94119. Epub 2014 Apr 8.

Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094119PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979749PMC
January 2015

NF-κB gene signature predicts prostate cancer progression.

Cancer Res 2014 May 31;74(10):2763-72. Epub 2014 Mar 31.

Authors' Affiliations: Department of Urologic Surgery and Vanderbilt Prostate Cancer Center; Division of Genetic Medicine, Department of Medicine; Departments of Cancer Biology and Medicine; and Division of Cancer Biostatistics, Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TennesseeAuthors' Affiliations: Department of Urologic Surgery and Vanderbilt Prostate Cancer Center; Division of Genetic Medicine, Department of Medicine; Departments of Cancer Biology and Medicine; and Division of Cancer Biostatistics, Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-2543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024337PMC
May 2014

The lymphatic system in malignant pleural effusion. Drain or immune switch?

Am J Respir Crit Care Med 2014 Mar;189(6):626-7

1 Department of Physiology University of Patras Rio, Greece.

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http://dx.doi.org/10.1164/rccm.201401-0140EDDOI Listing
March 2014

Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.

Lab Invest 2014 Apr 17;94(4):409-21. Epub 2014 Feb 17.

1] Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA [2] Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1038/labinvest.2014.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992484PMC
April 2014

A novel dyskerin (DKC1) mutation is associated with familial interstitial pneumonia.

Chest 2014 Jul;146(1):e1-e7

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.1378/chest.13-2224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077414PMC
July 2014

NF-κB inhibition after cecal ligation and puncture reduces sepsis-associated lung injury without altering bacterial host defense.

Mediators Inflamm 2013 18;2013:503213. Epub 2013 Nov 18.

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA ; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA ; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA ; Department of Veterans Affairs Medical Center, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1155/2013/503213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852536PMC
October 2014

Bronchoscopic cryobiopsy for the diagnosis of diffuse parenchymal lung disease.

PLoS One 2013 12;8(11):e78674. Epub 2013 Nov 12.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078674PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827078PMC
September 2014

Systemic delivery of microRNA-181b inhibits nuclear factor-κB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice.

Circ Res 2014 Jan 1;114(1):32-40. Epub 2013 Oct 1.

Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (X.S., S.H., A.K.M.W., B.I., E.S., Y.T., N.B., G.K.S., K.C., M.W.F.); Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (S.H., D.L.); and Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN (T.S.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.113.302089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051320PMC
January 2014

Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2.

Free Radic Biol Med 2013 Dec 9;65:1134-1142. Epub 2013 Sep 9.

Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 626-870, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.08.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972891PMC
December 2013

Targeting the Wnt pathway in synovial sarcoma models.

Cancer Discov 2013 Nov 6;3(11):1286-301. Epub 2013 Aug 6.

1Department of Cancer Biology, 2Division of Hepatobiliary Surgery, Department of Surgery, 3Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, and 4Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center; 5Department of Cell and Developmental Biology, Vanderbilt University; 6StemSynergy Therapeutics, Inc., Nashville, Tennessee; 7Department of Pediatrics-Nutrition, Baylor College of Medicine, Houston, Texas; and 8Department of Human Genetics, Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823757PMC
November 2013