Publications by authors named "Timothy R Gershon"

23Publications

Erbb4 Is Required for Cerebellar Developmentand Malignant Phenotype of Medulloblastoma.

Cancers (Basel) 2020 Apr 17;12(4). Epub 2020 Apr 17.

Cellular Oncology group, Biodonostia Health Research Institute, Dr. Beguiristain s/n, 20014 San Sebastian, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers12040997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226104PMC
April 2020

GSK-3 modulates SHH-driven proliferation in postnatal cerebellar neurogenesis and medulloblastoma.

Development 2019 10 10;146(20). Epub 2019 Oct 10.

UNC Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.177550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826032PMC
October 2019

Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic Pathway.

Cancer Res 2016 06 13;76(11):3211-23. Epub 2016 Apr 13.

UNC Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-15-0025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891232PMC
June 2016

AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.

Cell Metab 2016 Apr;23(4):649-62

Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham, NC 27710, USA; Duke Molecular Physiology Institute, Duke University, Durham, NC 27710, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832577PMC
April 2016

Energy metabolism in neurodevelopment and medulloblastoma.

Transl Pediatr 2015 Jan;4(1):12-9

1 Joint Department of Biomedical Engineering, NC State University and UNC Chapel Hill, Chapel Hill, NC 27599, USA ; 2 Department of Neurology, 3 Lineberger Comprehensive Cancer Center, 4 UNC Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3978/j.issn.2224-4336.2015.01.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729065PMC
January 2015

Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.

Cell Rep 2016 Jan 31;14(2):216-24. Epub 2015 Dec 31.

Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA; Neurobiology Curriculum, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2015.12.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716786PMC
January 2016

Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.

Development 2015 Nov 8;142(22):3921-32. Epub 2015 Oct 8.

Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA UNC Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.124271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712878PMC
November 2015

Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma.

Cancer Lett 2015 Jan 22;356(2 Pt A):268-72. Epub 2014 Feb 22.

Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2014.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141892PMC
January 2015

Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum.

Cancer Metab 2013 Jun 11;1(1):15. Epub 2013 Jun 11.

Department of Neurology, University of North Carolina, Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2049-3002-1-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178205PMC
June 2013

Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma.

J Neurosci 2013 Nov;33(46):18098-108

Departments of Neurology, Radiation Oncology, and Radiology, Neuroscience Center, Lineberger Comprehensive Cancer Center, and Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.2602-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828463PMC
November 2013

Tbata modulates thymic stromal cell proliferation and thymus function.

J Exp Med 2010 Oct 11;207(11):2521-32. Epub 2010 Oct 11.

Experimental Transplantation Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20092759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964569PMC
October 2010

Medulloblastoma: therapy and biologic considerations.

Curr Neurol Neurosci Rep 2006 May;6(3):200-6

Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11910-006-0006-yDOI Listing
May 2006

Temporally regulated neural crest transcription factors distinguish neuroectodermal tumors of varying malignancy and differentiation.

Neoplasia 2005 Jun;7(6):575-84

Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501286PMC
http://dx.doi.org/10.1593/neo.04637DOI Listing
June 2005