Timothy P Newsome

Timothy P Newsome

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Timothy P Newsome

Timothy P Newsome

Publications by authors named "Timothy P Newsome"

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Construction and Isolation of Recombinant Vaccinia Virus Expressing Fluorescent Proteins.

Methods Mol Biol 2019 ;2023:73-92

The University of Sydney, School of Life and Environmental Sciences, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/978-1-4939-9593-6_4DOI Listing
March 2020

Cell-to-cell spread of vaccinia virus is promoted by TGF-β-independent Smad4 signaling.

Cell Microbiol 2020 Mar 31:e13206. Epub 2020 Mar 31.

School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, 2006, Australia.

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http://dx.doi.org/10.1111/cmi.13206DOI Listing
March 2020

Phototracking Vaccinia Virus Transport Reveals Dynamics of Cytoplasmic Dispersal and a Requirement for A36R and F12L for Exit from the Site of Wrapping.

Viruses 2018 07 24;10(8). Epub 2018 Jul 24.

School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia.

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http://dx.doi.org/10.3390/v10080390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115981PMC
July 2018

Loss of Actin-Based Motility Impairs Ectromelia Virus Release In Vitro but Is Not Critical to Spread In Vivo.

Viruses 2018 03 5;10(3). Epub 2018 Mar 5.

School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia.

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http://dx.doi.org/10.3390/v10030111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869504PMC
March 2018

Viruses That Exploit Actin-Based Motility for Their Replication and Spread.

Handb Exp Pharmacol 2017 ;235:237-261

The School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/164_2016_41DOI Listing
September 2017

Divergent roles of β- and γ-actin isoforms during spread of vaccinia virus.

Cytoskeleton (Hoboken) 2017 Apr 17;74(4):170-183. Epub 2017 Mar 17.

School of Life and Environmental Sciences, The University of Sydney, Australia.

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http://doi.wiley.com/10.1002/cm.21356
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http://dx.doi.org/10.1002/cm.21356DOI Listing
April 2017

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice.

PLoS Pathog 2015 Dec 23;11(12):e1005342. Epub 2015 Dec 23.

Department of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1005342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689526PMC
December 2015

Viruses that ride on the coat-tails of actin nucleation.

Semin Cell Dev Biol 2015 Oct 13;46:155-63. Epub 2015 Oct 13.

School of Molecular Bioscience, The University of Sydney, Sydney, NSW, 2006, Australia.

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http://dx.doi.org/10.1016/j.semcdb.2015.10.008DOI Listing
October 2015

Vaccinia virus F5 is required for normal plaque morphology in multiple cell lines but not replication in culture or virulence in mice.

Virology 2014 May 5;456-457:145-56. Epub 2014 Apr 5.

Division of Biomedical Science and Biochemistry, Research School of Biology, The Australian National University, Canberra, ACT, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.03.020DOI Listing
May 2014

A36-dependent actin filament nucleation promotes release of vaccinia virus.

PLoS Pathog 2013 Mar 21;9(3):e1003239. Epub 2013 Mar 21.

School of Molecular Bioscience, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1003239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605287PMC
March 2013

Sub-viral imaging of vaccinia virus using super-resolution microscopy.

J Virol Methods 2012 Dec 7;186(1-2):132-6. Epub 2012 Jul 7.

School of Molecular Bioscience, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.jviromet.2012.07.003DOI Listing
December 2012

Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells.

PLoS Pathog 2012 7;8(6):e1002762. Epub 2012 Jun 7.

Laboratory of HIV Biology, Immunovirology and Pathogenesis Program, The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1002762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369929PMC
November 2012

Exhalation of respiratory viruses by breathing, coughing, and talking.

J Med Virol 2009 Sep;81(9):1674-9

Faculty of Science, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, NSW, Australia.

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http://dx.doi.org/10.1002/jmv.21556DOI Listing
September 2009

An E2-F12 complex is required for intracellular enveloped virus morphogenesis during vaccinia infection.

Cell Microbiol 2009 May 4;11(5):808-24. Epub 2009 Feb 4.

Cell Motility Laboratory, Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London, UK.

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http://dx.doi.org/10.1111/j.1462-5822.2009.01296.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688674PMC
May 2009

The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility.

Nature 2009 Mar;458(7234):87-91

Cell Motility Laboratory, Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1038/nature07773DOI Listing
March 2009

The release of vaccinia virus from infected cells requires RhoA-mDia modulation of cortical actin.

Cell Host Microbe 2007 May;1(3):227-40

Cell Motility Laboratory, Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1016/j.chom.2007.04.006DOI Listing
May 2007

Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation.

Mol Biol Cell 2007 Jan 1;18(1):142-52. Epub 2006 Nov 1.

Molecular Neuropathobiology, Cancer Research UK London Research Institute, London WC2A 3PX, United Kingdom.

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http://www.molbiolcell.org/doi/10.1091/mbc.e06-05-0453
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http://dx.doi.org/10.1091/mbc.e06-05-0453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751333PMC
January 2007

Abl collaborates with Src family kinases to stimulate actin-based motility of vaccinia virus.

Cell Microbiol 2006 Feb;8(2):233-41

Cell Motility Laboratory, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, WC2A 3PX, London, UK.

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http://dx.doi.org/10.1111/j.1462-5822.2005.00613.xDOI Listing
February 2006

SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus.

Science 2004 Oct 5;306(5693):124-9. Epub 2004 Aug 5.

Cell Motility Laboratory, Room 529, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1126/science.1101509DOI Listing
October 2004

A role for VASP in RhoA-Diaphanous signalling to actin dynamics and SRF activity.

EMBO J 2003 Jun;22(12):3050-61

Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, Transcription Laboratory, Room 401, 44 Lincoln's Inn Fields, London.

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http://dx.doi.org/10.1093/emboj/cdg287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC162139PMC
June 2003