Timothy Lockey

Timothy Lockey

UNVERIFIED PROFILE

Are you Timothy Lockey?   Register this Author

Register author
Timothy Lockey

Timothy Lockey

Publications by authors named "Timothy Lockey"

Are you Timothy Lockey?   Register this Author

19Publications

143Reads

-Profile Views

Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1.

N Engl J Med 2019 04;380(16):1525-1534

From the Departments of Bone Marrow Transplantation and Cellular Therapy (E.M., B.T., W.J., S.G.), Hematology (S.Z., Z.M., J.C., J.D., X.T., B.Y.R., M.J.W., B.P.S.), Therapeutics Production and Quality (T.L., M.M.M.), Immunology (H.A., B.Y.), Pharmaceutical Sciences (S.J.C.), Biostatistics (G.K., C.L.), and Infectious Diseases (G.M.), St. Jude Children's Research Hospital, Memphis, TN; the Allergy and Clinical Immunology Division, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru (J.C.A.B.); the Department of Pediatrics, Allergy-Immunology Division, Children's Hospital Los Angeles, Los Angeles (J.A.C.), and the Department of Pediatrics, Division of Pediatric Allergy-Immunology-Bone Marrow Transplantation, University of California, San Francisco (UCSF) Benioff Children's Hospital, San Francisco (J.R.L.-B., J.M.P., M.J.C.) - both in California; the Department of Pediatrics, Pediatric Allergy and Immunology, University of New Mexico, Albuquerque (E.D.); University of Oklahoma Health Sciences Center, Tulsa (J.T.L.); Departamento de Pediatria da Universidade de Taubaté, Conselho Nacional de Medicina, São Paulo (A.C.M.A.); Copperfield Childcare, Claremont, South Africa (H.W.); and the Genetic Immunotherapy Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (S.S.D.R., H.L.M.).

View Article

Download full-text PDF

Source
http://www.nejm.org/doi/10.1056/NEJMoa1815408
Publisher Site
http://dx.doi.org/10.1056/NEJMoa1815408DOI Listing
April 2019

Development and Optimization of AAV hFIX Particles by Transient Transfection in an iCELLis(®) Fixed-Bed Bioreactor.

Hum Gene Ther Methods 2016 06;27(3):112-21

Department of Therapeutics Production & Quality, St. Jude Children's Research Hospital , Memphis, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/hgtb.2016.021DOI Listing
June 2016

Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector.

Mol Ther Methods Clin Dev 2016 30;3:16015. Epub 2016 Mar 30.

Department of Therapeutics Production & Quality, St. Jude Children's Research Hospital , Memphis, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mtm.2016.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813606PMC
April 2016

Ex vivo activation of CD56(+) immune cells that eradicate neuroblastoma.

Cancer Res 2013 Apr 25;73(8):2608-18. Epub 2013 Feb 25.

Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-3322DOI Listing
April 2013

A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies.

Cytotherapy 2012 Aug 29;14(7):830-40. Epub 2012 Mar 29.

Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/14653249.2012.671519DOI Listing
August 2012

SHIV infection protects against heterologous pathogenic SHIV challenge in macaques: a gold-standard for HIV-1 vaccine development?

Curr HIV Res 2009 Sep;7(5):497-503

Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782824PMC
September 2009

Expansion of highly cytotoxic human natural killer cells for cancer cell therapy.

Cancer Res 2009 May 21;69(9):4010-7. Epub 2009 Apr 21.

Department of Oncology, Hartwell Center for Bioinformatics and Biotechnology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-08-3712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716664PMC
May 2009

Epstein-Barr virus vaccine development: a lytic and latent protein cocktail.

Front Biosci 2008 May 1;13:5916-27. Epub 2008 May 1.

Department of Immunology, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
May 2008

HIV-1 vaccine development: tackling virus diversity with a multi-envelope cocktail.

Front Biosci 2008 Jan 1;13:609-20. Epub 2008 Jan 1.

Department of Immunology, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
January 2008

A Multi-Vector, Multi-Envelope HIV-1 Vaccine.

J Pediatr Pharmacol Ther 2007 Apr;12(2):68-76

Departments of Immunology ; Infectious Diseases, St. Jude Children's Research Hospital ; Departments of Pathology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5863/1551-6776-12.2.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462093PMC
April 2007

Multi-envelope HIV-1 vaccine devoid of SIV components controls disease in macaques challenged with heterologous pathogenic SHIV.

Vaccine 2005 Nov 20;23(46-47):5306-20. Epub 2005 Jul 20.

Department of Infectious Diseases, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2005.07.008DOI Listing
November 2005

HIV vaccine rationale, design and testing.

Curr HIV Res 2005 Apr;3(2):107-12

Department of Infectious Diseases, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
April 2005

A five-residue HIV envelope helper T cell determinant: does this peptide-MHC interaction leave the binding groove half empty?

AIDS Res Hum Retroviruses 2002 Oct;18(15):1141-4

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/088922202320567888DOI Listing
October 2002