Timothy J Nice

Timothy J Nice

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Timothy J Nice

Timothy J Nice

Publications by authors named "Timothy J Nice"

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IFN-I and IL-22 mediate protective effects of intestinal viral infection.

Nat Microbiol 2019 10 10;4(10):1737-1749. Epub 2019 Jun 10.

Kimmel Center for Biology and Medicine, Skirball Institute of Biomedical Medicine, New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41564-019-0470-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871771PMC
October 2019

Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection.

Cell 2019 Oct 10;179(3):644-658.e13. Epub 2019 Oct 10.

Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.09.028DOI Listing
October 2019

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells.

PLoS Pathog 2019 07 22;15(7):e1007940. Epub 2019 Jul 22.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675124PMC
July 2019

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.

Cell Host Microbe 2019 06 23;25(6):845-857.e5. Epub 2019 May 23.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622463PMC
June 2019

Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells.

Cell Host Microbe 2018 11 1;24(5):665-676.e4. Epub 2018 Nov 1.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128183054
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http://dx.doi.org/10.1016/j.chom.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248887PMC
November 2018

The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus.

Trends Microbiol 2018 06 17;26(6):510-524. Epub 2017 Nov 17.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.1016/j.tim.2017.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957778PMC
June 2018

Norovirus Cell Tropism Is Determined by Combinatorial Action of a Viral Non-structural Protein and Host Cytokine.

Cell Host Microbe 2017 Oct 28;22(4):449-459.e4. Epub 2017 Sep 28.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679710PMC
October 2017

Differentiation and Protective Capacity of Virus-Specific CD8 T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche.

Immunity 2017 10 11;47(4):723-738.e5. Epub 2017 Oct 11.

Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077984PMC
October 2017

You Can Breathe Easy: IFNλ Handles Flu without Triggering a Damaging Inflammatory Response.

Immunity 2017 05;46(5):768-770

Oregon Health & Science University, Portland, OR 97239, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.04.027DOI Listing
May 2017

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

PLoS Pathog 2016 06 21;12(6):e1005684. Epub 2016 Jun 21.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915689PMC
June 2016

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond.

Immunity 2015 Jul;43(1):15-28

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527169PMC
July 2015

Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity.

Science 2015 Jan 27;347(6219):269-73. Epub 2014 Nov 27.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/science.1258100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398891PMC
January 2015

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection.

Science 2015 Jan 27;347(6219):266-9. Epub 2014 Nov 27.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/science.1258025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409937PMC
January 2015

Type I interferons link viral infection to enhanced epithelial turnover and repair.

Cell Host Microbe 2015 Jan 4;17(1):85-97. Epub 2014 Dec 4.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2014.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297260PMC
January 2015

Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.

Science 2014 Aug 17;345(6196):578-82. Epub 2014 Jul 17.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1256942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548887PMC
August 2014

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence.

J Virol 2013 Jan 17;87(1):327-34. Epub 2012 Oct 17.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1128/JVI.01864-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536416PMC
January 2013

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

J Immunol 2010 Nov 24;185(9):5369-76. Epub 2010 Sep 24.

Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720-3200, USA.

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http://dx.doi.org/10.4049/jimmunol.1000247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001296PMC
November 2010

Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress.

J Exp Med 2009 Feb 26;206(2):287-98. Epub 2009 Jan 26.

Department of Molecular and Cell Biology and Cancer Research Laboratory, University of California, Berkeley, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1084/jem.20081335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646581PMC
February 2009