Timothy J Mead

Timothy J Mead

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Timothy J Mead

Timothy J Mead

Publications by authors named "Timothy J Mead"

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Expression Analysis by RNAscope™ In Situ Hybridization.

Methods Mol Biol 2020 ;2043:173-178

Department of Biomedical Engineering-ND20, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-1-4939-9698-8_14DOI Listing
January 2020

Alizarin Red and Alcian Blue Preparations to Visualize the Skeleton.

Authors:
Timothy J Mead

Methods Mol Biol 2020 ;2043:207-212

Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-1-4939-9698-8_17DOI Listing
January 2020

Visualization and Quantification of Pericellular Matrix.

Methods Mol Biol 2020 ;2043:261-264

Department of Biomedical Engineering-ND20, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-1-4939-9698-8_21DOI Listing
January 2020

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

Matrix Biol 2019 04 7;77:117-128. Epub 2018 Sep 7.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.09.004DOI Listing
April 2019

ADAMTS proteins in human disorders.

Matrix Biol 2018 10 6;71-72:225-239. Epub 2018 Jun 6.

Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, United States. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146047PMC
October 2018

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.

Authors:
Bram P Prins Timothy J Mead Jennifer A Brody Gardar Sveinbjornsson Ioanna Ntalla Nathan A Bihlmeyer Marten van den Berg Jette Bork-Jensen Stefania Cappellani Stefan Van Duijvenboden Nikolai T Klena George C Gabriel Xiaoqin Liu Cagri Gulec Niels Grarup Jeffrey Haessler Leanne M Hall Annamaria Iorio Aaron Isaacs Ruifang Li-Gao Honghuang Lin Ching-Ti Liu Leo-Pekka Lyytikäinen Jonathan Marten Hao Mei Martina Müller-Nurasyid Michele Orini Sandosh Padmanabhan Farid Radmanesh Julia Ramirez Antonietta Robino Molly Schwartz Jessica van Setten Albert V Smith Niek Verweij Helen R Warren Stefan Weiss Alvaro Alonso David O Arnar Michiel L Bots Rudolf A de Boer Anna F Dominiczak Mark Eijgelsheim Patrick T Ellinor Xiuqing Guo Stephan B Felix Tamara B Harris Caroline Hayward Susan R Heckbert Paul L Huang J W Jukema Mika Kähönen Jan A Kors Pier D Lambiase Lenore J Launer Man Li Allan Linneberg Christopher P Nelson Oluf Pedersen Marco Perez Annette Peters Ozren Polasek Bruce M Psaty Olli T Raitakari Kenneth M Rice Jerome I Rotter Moritz F Sinner Elsayed Z Soliman Tim D Spector Konstantin Strauch Unnur Thorsteinsdottir Andrew Tinker Stella Trompet André Uitterlinden Ilonca Vaartjes Peter van der Meer Uwe Völker Henry Völzke Melanie Waldenberger James G Wilson Zhijun Xie Folkert W Asselbergs Marcus Dörr Cornelia M van Duijn Paolo Gasparini Daniel F Gudbjartsson Vilmundur Gudnason Torben Hansen Stefan Kääb Jørgen K Kanters Charles Kooperberg Terho Lehtimäki Henry J Lin Steven A Lubitz Dennis O Mook-Kanamori Francesco J Conti Christopher H Newton-Cheh Jonathan Rosand Igor Rudan Nilesh J Samani Gianfranco Sinagra Blair H Smith Hilma Holm Bruno H Stricker Sheila Ulivi Nona Sotoodehnia Suneel S Apte Pim van der Harst Kari Stefansson Patricia B Munroe Dan E Arking Cecilia W Lo Yalda Jamshidi

Genome Biol 2018 07 17;19(1):87. Epub 2018 Jul 17.

Genetics Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London, SW17 0RE, UK.

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http://dx.doi.org/10.1186/s13059-018-1457-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048820PMC
July 2018

The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.

JCI Insight 2018 04 5;3(7). Epub 2018 Apr 5.

Department of Biomedical Engineering and the Orthopaedic and Rheumatologic Institute, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1172/jci.insight.92941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928868PMC
April 2018

Versican Proteolysis by ADAMTS Proteases and Its Influence on Sex Steroid Receptor Expression in Uterine Leiomyoma.

J Clin Endocrinol Metab 2017 05;102(5):1631-1641

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195.

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http://dx.doi.org/10.1210/jc.2016-3527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443325PMC
May 2017

The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers.

Nucleic Acids Res 2015 Jun 4;43(11):5394-408. Epub 2015 May 4.

Department of Cellular & Molecular Medicine, and Orthopaedic and Rheumatologic Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA

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http://dx.doi.org/10.1093/nar/gkv426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477657PMC
June 2015

Proliferation assays (BrdU and EdU) on skeletal tissue sections.

Methods Mol Biol 2014 ;1130:233-243

Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-1-62703-989-5_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074019PMC
September 2014

A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration.

Nucleic Acids Res 2013 Apr 28;41(8):4459-69. Epub 2013 Feb 28.

Department of Cellular and Molecular Medicine, and Orthopaedic and Rheumatologic Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1093/nar/gkt140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632127PMC
April 2013

Notch signaling and the developing skeleton.

Adv Exp Med Biol 2012 ;727:114-30

Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/978-1-4614-0899-4_9DOI Listing
April 2012

Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development.

Dev Dyn 2012 Mar 25;241(3):493-504. Epub 2012 Jan 25.

Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1002/dvdy.23739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288604PMC
March 2012

Notch pathway regulation of neural crest cell development in vivo.

Dev Dyn 2012 Feb 3;241(2):376-89. Epub 2012 Jan 3.

The Heart Institute, Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1002/dvdy.23717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266628PMC
February 2012

Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development.

Proc Natl Acad Sci U S A 2009 Aug 9;106(34):14420-5. Epub 2009 Jul 9.

Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1073/pnas.0902306106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732875PMC
August 2009

Lymphangiogenesis in the developing lung promoted by VEGF-A.

Microvasc Res 2006 Jul-Sep;72(1-2):62-73. Epub 2006 Jun 23.

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.mvr.2006.05.002DOI Listing
January 2007