Timothy Hinks

Timothy Hinks

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Timothy Hinks

Timothy Hinks

Publications by authors named "Timothy Hinks"

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Is there a role for type 2 CD8 T cells in patients with steroid-resistant asthma?

J Allergy Clin Immunol 2019 Sep 31;144(3):648-650. Epub 2019 Jul 31.

Respiratory Medicine Unit and National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), Nuffield Department of Medicine Experimental Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2019.07.022DOI Listing
September 2019

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions.

Cell Rep 2019 Sep;28(12):3077-3091.e5

Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, UK; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DU, UK; NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.050DOI Listing
September 2019

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality.

Cell Rep 2019 Sep;28(12):3249-3262.e5

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

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http://dx.doi.org/10.1016/j.celrep.2019.07.039DOI Listing
September 2019

Cytometric Gating Stringency Impacts Studies of Type 2 Innate Lymphoid Cells in Asthma.

Am J Respir Cell Mol Biol 2017 12;57(6):745-747

1 University of Oxford Oxford, United Kingdom and.

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http://dx.doi.org/10.1165/rcmb.2017-0201LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765422PMC
December 2017

Coal mine dust lung disease in the modern era.

Respirology 2017 05 30;22(4):662-670. Epub 2017 Mar 30.

Lung Health Research Centre (LHRC), The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/resp.13034DOI Listing
May 2017

Metabolomics analysis identifies different metabotypes of asthma severity.

Eur Respir J 2017 03 29;49(3). Epub 2017 Mar 29.

Division of Physiological Chemistry 2, Dept of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1183/13993003.01740-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399350PMC
March 2017

Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1.

J Allergy Clin Immunol 2016 07 3;138(1):61-75. Epub 2016 Feb 3.

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, Southampton, United Kingdom; NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2015.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929135PMC
July 2016

Mucosal-associated invariant T cells in autoimmunity, immune-mediated diseases and airways disease.

Immunology 2016 May 9;148(1):1-12. Epub 2016 Feb 9.

Department for Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/imm.12582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819138PMC
May 2016

Reduced Numbers and Proapoptotic Features of Mucosal-associated Invariant T Cells as a Characteristic Finding in Patients with Inflammatory Bowel Disease.

Inflamm Bowel Dis 2015 Dec;21(12):E30

Clinical and Experimental Sciences, Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, University of Southampton, Southampton, United Kingdom NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1097/MIB.0000000000000637DOI Listing
December 2015

Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms.

J Allergy Clin Immunol 2015 Aug 5;136(2):323-33. Epub 2015 Mar 5.

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, Southampton, United Kingdom; NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom. Electronic address:

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https://www.researchgate.net/profile/Borislav_D_Dimitrov/pub
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http://linkinghub.elsevier.com/retrieve/pii/S009167491500104
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http://dx.doi.org/10.1016/j.jaci.2015.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534770PMC
August 2015

A novel lung explant model for the ex vivo study of efficacy and mechanisms of anti-influenza drugs.

J Immunol 2015 Jun 1;194(12):6144-54. Epub 2015 May 1.

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Southampton SO16 6YD, United Kingdom; Southampton National Institute for Health Research Respiratory Biomedical Research Unit, Southampton General Hospital, Southampton SO16 6YD, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1402283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456633PMC
June 2015

Multidimensional endotypes of asthma: topological data analysis of cross-sectional clinical, pathological, and immunological data.

Lancet 2015 Feb;385 Suppl 1:S42

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, Southampton, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736156035
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http://dx.doi.org/10.1016/S0140-6736(15)60357-9DOI Listing
February 2015

Phenotypic characterization of lung macrophages in asthmatic patients: overexpression of CCL17.

J Allergy Clin Immunol 2012 Dec 14;130(6):1404-12.e7. Epub 2012 Sep 14.

Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2012.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805016PMC
December 2012

High background rates of positive tuberculosis-specific interferon-γ release assays in a low prevalence region of UK: a surveillance study.

BMC Infect Dis 2012 Dec 6;12:339. Epub 2012 Dec 6.

Academic Unit of Clinical and Experimental Sciences, Mailpoint 0810, University of Southampton Faculty of Medicine, Southampton General Hospital, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1186/1471-2334-12-339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537536PMC
December 2012

Mycobacterium tuberculosis-specific cellular immune profiles suggest bacillary persistence decades after spontaneous cure in untreated tuberculosis.

J Infect Dis 2010 Dec 19;202(11):1685-9. Epub 2010 Oct 19.

Tuberculosis Research Unit, Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1086/656772DOI Listing
December 2010

Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load.

J Immunol 2007 Apr;178(8):5217-26

Tuberculosis Immunology Group, Department of Respiratory Medicine, National Heart and Lung Institute, Wright Fleming Institute of Infection and Immunity, Imperial College London, London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743164PMC
http://dx.doi.org/10.4049/jimmunol.178.8.5217DOI Listing
April 2007