Timothy D Girard

Timothy D Girard

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Timothy D Girard

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Association of neuronal repair biomarkers with delirium among survivors of critical illness.

J Crit Care 2020 Apr 16;56:94-99. Epub 2019 Dec 16.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN, United States.

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http://dx.doi.org/10.1016/j.jcrc.2019.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080575PMC
April 2020

On the Road to a Delirium Assay.

Crit Care Med 2020 Mar;48(3):431-432

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA The Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000004208DOI Listing
March 2020

Provider Perspectives on Preventive Postextubation Noninvasive Ventilation for High-Risk Intensive Care Unit Patients.

Ann Am Thorac Soc 2020 Feb;17(2):246-249

University of Pittsburgh School of MedicinePittsburgh, Pennsylvania.

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http://dx.doi.org/10.1513/AnnalsATS.201904-295RLDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993795PMC
February 2020

Sex Disparities and Functional Outcomes after Critical Illness.

Am J Respir Crit Care Med 2019 Nov 21. Epub 2019 Nov 21.

University of Pittsburgh, 6614, Department of Critical Care Medicine, Pittsburgh, Pennsylvania, United States.

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http://dx.doi.org/10.1164/rccm.201902-0328LEDOI Listing
November 2019

Mitochondrial DNA Haplogroups and Delirium During Sepsis.

Crit Care Med 2019 Aug;47(8):1065-1071

Clinical Research, Investigation, and Systems Modeling of Acute illness (CRISMA) Center in the Department of Critical Care Medicine, University of Pittsburgh School of Medicine.

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http://dx.doi.org/10.1097/CCM.0000000000003810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012366PMC
August 2019

Revisiting, Reframing, and Casting a New Light on Liberation From Mechanical Ventilation.

JAMA 2019 06;321(22):2167-2169

Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.2019.7364DOI Listing
June 2019

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. Reply.

N Engl J Med 2019 05;380(18):1779-1780

VA Geriatric Research, Education, and Clinical Service Center, Nashville, TN

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http://dx.doi.org/10.1056/NEJMc1901272DOI Listing
May 2019

Delirium in the critically ill patient.

Handb Clin Neurol 2019 ;167:357-375

Department of Critical Care Medicine, Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-804766-8.00019-4DOI Listing
January 2019

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness.

N Engl J Med 2018 12 22;379(26):2506-2516. Epub 2018 Oct 22.

From the Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh (T.D.G.); the Pulmonary, Critical Care, and Sleep Medicine Division, Department of Medicine, Ohio State University Wexner Medical Center, Columbus (M.C.E.), and the Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic Foundation, Cleveland (R.D.H.) - both in Ohio; the Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill (S.S.C.), the Section on Critical Care, Department of Anesthesiology, Wake Forest Baptist Health, Winston-Salem (D.L.B.), and Cone Health System, Greensboro (D.J.F.) - all in North Carolina; the Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine, Seattle (C.L.H.); the Department of Anesthesiology, University of Maryland School of Medicine, Baltimore (P.R.); the Division of Critical Care Medicine, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, New York (M.N.G.); the Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, Denver Health Medical Center, Denver (I.S.D.); the Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California at San Diego, San Diego (A.M., R.L.O.); the Division of Pulmonary, Critical Care, Sleep, and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis (B.K.); the Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT (M.A.P.); the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor (R.C.H.); the Division of Pulmonary, Critical Care, and Occupational Medicine, Department of Medicine, University of Iowa Hospitals and Clinics, Iowa City (G.A.S.); , and the Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia (W.D.S.); the Center for Clinical Effectiveness, Baylor Scott and White Health, Dallas (A.L.M.); and the Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center (J.L.T., R.C., B.T.P., C.S., L.M.B., J.C.J., P.P.P., N.E.B., C.G.H., M.B.P., J.L.S., G.R.B., R.S.D., E.W.E.), the Center for Health Services Research (R.C., J.C.J., C.S., N.E.B., R.S.D., E.W.E.), the Center for Quality Aging (N.E.B., E.W.E.), the Division of Allergy, Pulmonary, and Critical Care Medicine (J.C.J., C.S., N.E.B., G.R.B., E.W.E.), the Division of General Internal Medicine and Public Health (R.S.D.), Department of Medicine, the Department of Biostatistics (J.L.T., R.C.), the Department of Psychiatry (J.C.J.), the Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology (P.P.P., C.G.H.), the Division of Trauma and Surgical Critical Care, Department of Surgery (M.B.P.), and the Department of Pharmaceutical Services (J.L.S.), Vanderbilt University School of Medicine, Vanderbilt University School of Nursing (L.M.B.), and the Anesthesia Service (P.P.P., C.G.H.), Research Service (J.C.J.), Surgical Service (M.B.P.), and Geriatric Research, Education, and Clinical Center Service (R.S.D., E.W.E.), Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System - all in Nashville.

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http://dx.doi.org/10.1056/NEJMoa1808217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364999PMC
December 2018

The Hospital Elder Life Program: Past and Future.

Am J Geriatr Psychiatry 2018 10 6;26(10):1034-1035. Epub 2018 Aug 6.

Scheunemann: Divisions of Geriatric Medicine and Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh; Girard: Department of Critical Care Medicine, University of Pittsburgh; Skidmore: Department of Occupational Therapy, University of Pittsburgh; Resnick: Division of Geriatric Medicine, University of Pittsburgh.

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http://dx.doi.org/10.1016/j.jagp.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545575PMC
October 2018

Sedation, Delirium, and Cognitive Function After Critical Illness.

Authors:
Timothy D Girard

Crit Care Clin 2018 Oct;34(4):585-598

Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 638 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccc.2018.06.009DOI Listing
October 2018

Co-Occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness.

Crit Care Med 2018 09;46(9):1393-1401

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1097/CCM.0000000000003218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095801PMC
September 2018

Acute Brain Dysfunction: Development and Validation of a Daily Prediction Model.

Chest 2018 08 24;154(2):293-301. Epub 2018 Mar 24.

Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN; Geriatric Research, Education and Clinical Center (GRECC) of the VA Tennessee Valley Healthcare System, Nashville, TN; Center for Health Services Research, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; Center for Quality Aging, Vanderbilt University Medical Center, Nashville, TN. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113630PMC
August 2018

Long-Term Cognitive Impairment after Hospitalization for Community-Acquired Pneumonia: a Prospective Cohort Study.

J Gen Intern Med 2018 06 26;33(6):929-935. Epub 2018 Jan 26.

Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1007/s11606-017-4301-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975139PMC
June 2018

The Sandman in the ICU: A Novel Use of Dexmedetomidine?

Am J Respir Crit Care Med 2018 05;197(9):1098-1099

2 Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201802-0359EDDOI Listing
May 2018

Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study.

Lancet Respir Med 2018 03;6(3):213-222

ICU Delirium and Cognitive Impairment Study Group at the Vanderbilt University School of Medicine, Nashville, Tennessee, USA; Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN, USA; Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.

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http://dx.doi.org/10.1016/S2213-2600(18)30062-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709878PMC
March 2018

Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability.

Intensive Care Med 2018 03 9;44(3):345-355. Epub 2018 Mar 9.

Department of Critical Care Medicine and Clinical Research, Investigation and Systems Modeling of Acute Illnesses Center, University of Pittsburgh, Pittsburgh, USA.

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http://dx.doi.org/10.1007/s00134-018-5120-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870884PMC
March 2018

Statistical methods to compare functional outcomes in randomized controlled trials with high mortality.

BMJ 2018 01 3;360:j5748. Epub 2018 Jan 3.

Clinical Research, Investigation, and Systems Modeling of Acute illness (CRISMA) Center in the Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751848PMC
http://dx.doi.org/10.1136/bmj.j5748DOI Listing
January 2018

Worldwide Survey of the "Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment" (ABCDEF) Bundle.

Crit Care Med 2017 Nov;45(11):e1111-e1122

1Department of Rehabilitation, Ancelle Hospital, Cremona, Italy. 2Geriatric Research Group, Brescia, Italy. 3Department of Anesthesia, Critical Care and Emergency, SpedaliCivili University Hospital, Brescia, Italy. 4Division of Pulmonary and Critical Care and Health Services Research, Vanderbilt University and VA Geriatric Research Education Clinical Center (GRECC), Nashville, TN. 5Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Mumbai, India. 6Department of Critical Care, D'or Institute for Research and Education and Post-Graduate Program Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. 7Addis Hiwot General Hospital, Addis Ababa, Ethiopia. 8Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA team, Biostatistics and clinical epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris Diderot Sorbonne University, Paris, France. 9School of Medicine and Surgery, University of Milano-Bicocca, Milano Geriatric Clinic, San Gerardo University Hospital, Monza, Italy. 10Department of Anaesthesia and Intensive Care, Medical Centre, Hungarian Defence Force, Budapest, Hungary. 11Interdepartmental Division of Critical Care Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. 12University Health Network, Toronto, ON, Canada. 13CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh and UPMC Health System, Pittsburgh, PA. 14International Research Project Humanizing Intensive Care (Proyecto HU-CI), Intensive Care Unit, Hospital Universitario de Torrejón, Madrid. Spain. 15Department of Emergency and Critical Care Medicine, Tokai University, School of Medicine, Kanagawa, Japan. 16Department of Pulmonary and Critical Care Medicine Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 17General Hospital Novo mesto, Novo mesto, Slovenia. 18Department of Anaesthesia, Intensive Care and Acute Poisioning, Pomeranian Medical University, Szczecin, Poland. 19Aga Khan University Hospital, Nairobi, Kenya. 20Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine Vanderbilt University Medical Center, Nashville, TN. 21Siriraj Hospital, Bangkok, Thailand. 22Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing, China. 23Department of Intensive Care Medicine Raymond Poincaré Hospital, Paris, France. 24School of Clinical Sciences, Faculty of Medicine, Monash University & Medical Center, Melbourne, VIC, Australia. 25University New South Wales, Clinical School of Medicine, NSW, Australia. 26Department of Medicine, McGill University, Montreal, QC, Canada. 27Regroupement de Soins Critiques Respiratoires, Réseau de Santé Respiratoire FRQS, Montreal, QC, Canada. 28Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. 29Krembil Neuroscience Centre, University Health Network, Toronto, ON, Canada. 30Department of Intensive Care Medicine, Brain Center Rudolf Magnus, Utrecht University, University Medical Center Utrecht, The Netherlands. 31Department of Neurocritical Care, University College London Hospitals, UCLH/UCL National Institute for Health Research Biomedical Research Centre, London, United Kingdom. 32Acute & General Medicine, Yamaguchi Graduate School of Medicine, Yamaguchi, Japan. 33Department of Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy. 34Department of Anesthesia, Critical Care and Emergency, Spedali Civili University Hospital, Brescia, Italy.

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http://dx.doi.org/10.1097/CCM.0000000000002640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640479PMC
November 2017

Delirium and Catatonia in Critically Ill Patients: The Delirium and Catatonia Prospective Cohort Investigation.

Crit Care Med 2017 Nov;45(11):1837-1844

1Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN. 2Veteran's Affairs Tennessee Valley Healthcare System, Geriatrics, Research, Education and Clinical Center (GRECC), Nashville, TN. 3Division of General Internal Medicine and Public Health, Department of Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN. 4Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN. 5Department of Critical Care Medicine, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, University of Pittsburgh School of Medicine, Pittsburgh, PA. 6Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN. 7Department of Psychiatry, Penn State Medical School, Hershey Medical Center, Hershey, PA. 8Department of Psychiatry, Beth Israel Deaconess Hospital-Plymouth, Plymouth, MA. 9Division of Pulmonary and Critical Care, Department of Medicine, and the Institute for Medicine and Public Health, the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1097/CCM.0000000000002642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678952PMC
November 2017

Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients.

Pharmacotherapy 2017 Nov 17;37(11):1357-1365. Epub 2017 Oct 17.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1002/phar.2021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681431PMC
November 2017

Subsyndromal Delirium and Institutionalization Among Patients With Critical Illness.

Am J Crit Care 2017 Nov;26(6):447-455

Nathan E. Brummel is an assistant professor and E. Wesley Ely is a professor, Department of Medicine, Center for Quality Aging and the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee. Dr Ely is also the associate director for research for the Geriatric Research, Education, and Clinical Center Service (GRECC), Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Leanne M. Boehm is a postdoctoral fellow, Vanderbilt University School of Nursing, a quality scholar, GRECC, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, and a research nurse, Department of Medicine, Center for Health Services Research, Vanderbilt University Medical Center. Timothy D. Girard is an associate professor, Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Pratik P. Pandharipande is a professor and Christopher G. Hughes is an associate professor, Department of Anesthesiology, Vanderbilt University Medical Center. James C. Jackson is a research associate professor, Department of Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, and Mayur B. Patel is an assistant professor, Department of Surgery, Vanderbilt University Medical Center. Jin H. Han is an associate professor, Department of Emergency Medicine and Center for Quality Aging, Vanderbilt University Medical Center. Eduard E. Vasilevskis is a staff physician, GRECC, Department of Veterans Affairs Medical Center, VA Tennessee Valley Healthcare System, and an assistant professor, Department of Medicine and Center for Health Services Research, Vanderbilt University Medical Center. Jennifer L. Thompson is a biostatistician and Rameela Chandrasekhar is an assistant professor, Department of Biostatistics, Vanderbilt University School of Medicine. Gordon R. Bernard is associate vice-chancellor for research and a professor, Department of Medicine, Vanderbilt University Medical Center. Robert S. Dittus is director, GRECC, Department of Veterans Affairs Medical Center, VA Tennessee Valley Healthcare System, and a professor, Department of Medicine, Vanderbilt University Medical Center.

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http://dx.doi.org/10.4037/ajcc2017263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831547PMC
November 2017

Surgery and Anesthesia Exposure Is Not a Risk Factor for Cognitive Impairment After Major Noncardiac Surgery and Critical Illness.

Ann Surg 2017 06;265(6):1126-1133

*Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine and Center for Health Services Research, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee †Section of Surgical Sciences, Departments of Surgery, Neurosurgery and Hearing and Speech Sciences, Division of Trauma and, Surgical Critical Care, and Emergency General Surgery, Vanderbilt Brain Institute, Center for Health Services Research, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee ‡Department of Medicine, Division of Pulmonary and Critical Care Medicine and Center for Health Services Research, Vanderbilt University Medical Center, Research Service, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee §Department of Medicine, Division of Pulmonary and Critical Care Medicine and Center for Health Services Research, Vanderbilt University Medical Center, Geriatric Research, Education and Clinical Center Service, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee ¶Department of Surgery, Radiology, and Radiological Sciences, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee ||Department of Medicine, Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee **Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee ††Department of Medicine, Division of Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee ‡‡Section of Surgical Sciences, Department of Surgery, Division of Trauma and Surgical Critical Care, and Emergency General Surgery, Vanderbilt University Medical Center, Nashville, Tennessee §§Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah ¶¶George E. Wahlen Department of Veterans Affairs Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah ||||Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Seattle Division, Veterans Affairs Puget Sound Health Care System, Seattle, Washington ***Clinical Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, the Netherlands †††Departments of Anesthesiology and Surgery, Division of Anesthesiology Critical Care Medicine, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee.

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http://dx.doi.org/10.1097/SLA.0000000000001885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856253PMC
June 2017

Inference in randomized trials with death and missingness.

Biometrics 2017 06 17;73(2):431-440. Epub 2016 Oct 17.

Helsinn Therapeutics (U.S.), Inc., Iselin, New Jersey, U.S.A.

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http://dx.doi.org/10.1111/biom.12594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383567PMC
June 2017

Acute Kidney Injury as a Risk Factor for Delirium and Coma during Critical Illness.

Am J Respir Crit Care Med 2017 06;195(12):1597-1607

12 Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201603-0476OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476907PMC
June 2017

Response.

Chest 2017 06;151(6):1400-1401

Section of Pulmonary and Critical Care, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1016/j.chest.2017.03.051DOI Listing
June 2017

Lung-Brain Interaction after Cardiac Arrest?

Am J Respir Crit Care Med 2017 05;195(9):1127-1128

1 Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania and.

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http://www.atsjournals.org/doi/10.1164/rccm.201703-0611ED
Publisher Site
http://dx.doi.org/10.1164/rccm.201703-0611EDDOI Listing
May 2017

Response.

Chest 2017 05;151(5):1180-1181

Division of Pulmonary Diseases, Critical Care and Occupational Medicine, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1016/j.chest.2017.02.027DOI Listing
May 2017

Exploring Delirium's Heterogeneity: Association Between Arousal Subtypes at Initial Presentation and 6-Month Mortality in Older Emergency Department Patients.

Am J Geriatr Psychiatry 2017 Mar 4;25(3):233-242. Epub 2016 Jul 4.

Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN; Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN; Geriatric Research, Education, and Clinical Center, Department of Veterans Affairs Medical Center, Tennessee Valley Health Care Center, Nashville, TN.

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http://dx.doi.org/10.1016/j.jagp.2016.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321606PMC
March 2017

Liberation from Mechanical Ventilation in Critically Ill Adults. An Official ATS/ACCP Clinical Practice Guideline.

Ann Am Thorac Soc 2017 03;14(3):441-443

8 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1513/AnnalsATS.201612-993CMEDOI Listing
March 2017

Limiting sedation for patients with acute respiratory distress syndrome - time to wake up.

Curr Opin Crit Care 2017 Feb;23(1):45-51

aDivision of Pulmonary, Allergy, and Critical Care Medicine bDepartment of Critical Care Medicine, CRISMA Center, University of Pittsburgh cVA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MCC.0000000000000382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729753PMC
February 2017

Employment Outcomes After Critical Illness: An Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological Dysfunction in ICU Survivors Cohort.

Crit Care Med 2016 Nov;44(11):2003-2009

1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 2Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 3Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 4Department of Psychiatry, Vanderbilt Medical Center, Nashville, TN. 5Department of Health Policy, Vanderbilt University School of Medicine, Nashville, TN. 6Center for Quality of Aging, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 7Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 8Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN. 9Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069078PMC
http://dx.doi.org/10.1097/CCM.0000000000001849DOI Listing
November 2016

Cognitive Impairment and Critical Illness: A Chicken and an Egg.

Crit Care Med 2016 11;44(11):2115-2116

Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh, PA The Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center Department of Critical Care Medicine University of Pittsburgh; and Veterans Affairs Pittsburgh Healthcare System Pittsburgh, PA.

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http://dx.doi.org/10.1097/CCM.0000000000001934DOI Listing
November 2016

Antipsychotic prescribing patterns during and after critical illness: a prospective cohort study.

Crit Care 2016 11 24;20(1):378. Epub 2016 Nov 24.

Clinical Research, Investigation, and Systems Modeling of Acute illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1186/s13054-016-1557-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122157PMC
November 2016

Critical Illness Brain Injury.

Annu Rev Med 2016 ;67:497-513

Division of Allergy, Pulmonary, and Critical Care Medicine.

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http://dx.doi.org/10.1146/annurev-med-050913-015722DOI Listing
October 2016

Endothelial Activation and Blood-Brain Barrier Injury as Risk Factors for Delirium in Critically Ill Patients.

Crit Care Med 2016 09;44(9):e809-17

1Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN.2Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.3Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Health Care System, Nashville, TN.4Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.5Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.6Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN.7Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Health Care System, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987204PMC
September 2016

The authors reply.

Crit Care Med 2016 06;44(6):e451-2

Center for Health Services Research and Section of Hospital Medicine, Division of General Internal Medicine and Public Health, Vanderbilt University, Nashville, TN, and Geriatric Research, Education and Clinical Center (GRECC) Service, Tennessee Valley Healthcare System, Nashville TN; Center for Health Services Research and Division of Allergy, Pulmonary, and Critical Care Medicine in the Department of Medicine, Vanderbilt University, Nashville, TN, and Geriatric Research, Education and Clinical Center (GRECC) Service, Tennessee Valley Healthcare System, Nashville TN; Center for Health Services Research and Division of Allergy, Pulmonary, and Critical Care Medicine in the Department of Medicine, Vanderbilt University, Nashville, TN, and Geriatric Research, Education and Clinical Center (GRECC) Service, Tennessee Valley Healthcare System, Nashville TN.

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June 2016

The impact of lymphopenia on delirium in ICU patients.

PLoS One 2015 20;10(5):e0126216. Epub 2015 May 20.

Division of Allergy/Pulmonary/Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America; Veterans Affairs Tennessee Valley Geriatric Research, Education and Clinical Center (GRECC), Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439144PMC
April 2016

Validity of a Modified Sequential Organ Failure Assessment Score Using the Richmond Agitation-Sedation Scale.

Crit Care Med 2016 Jan;44(1):138-46

1Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN.2Section of Hospital Medicine, Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.3Geriatric Research, Education, and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.4Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN.5Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.6Department of Urology, Vanderbilt University School of Medicine, Nashville, TN.7Department of Clinical Epidemiology and Biostatistics, Graduate School of Medicine, Osaka University, Osaka, Japan.8Advanced Medical Emergency and Critical Care Center, Yamaguchi University Hospital, Yamaguchi, Japan.9Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748963PMC
January 2016

Population Pharmacokinetics of Fentanyl in the Critically Ill.

Crit Care Med 2016 Jan;44(1):64-72

1Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.2Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.3Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.4Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN.5Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.6Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN.7Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.8Aegis Sciences Corporation, Nashville, TN.9Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN.10Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.11Division of Rheumatology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755937PMC
January 2016

Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.

Crit Care Med 2015 Oct;43(10):2076-84

1Division of Pulmonary, Allergy and Critical Care, Emory University, Atlanta, GA. 2Division of Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD. 3Department of Anesthesia, Mayo Clinic, Rochester, MN. 4Department of Anesthesiology, Stanford University, Palo Alto, CA. 5Division of Pulmonary and Critical Care, Intermountain Medical Center and University of Utah, Salt Lake City, UT. 6Division of Pulmonary and Critical Care, UCLA, Los Angeles, CA. 7Division of Pulmonary and Critical Care Medicine, Columbia University Medical Center, New York, NY. 8Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, CT. 9Division of Pulmonary and Critical Care, Meharry Medical College, Nashville, TN. 10Division of Allergy, Pulmonary, and Critical Care Medicine and Center for Health Services Research at the, Vanderbilt University School of Medicine, Nashville, TN. 11Division of Pulmonary and Critical Care, Drexel University, Philadelphia, PA. 12Department of Surgical Critical Care, University of Maryland, Baltimore, MD. 13Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, PA. 14Division of Pulmonary Critical Care and Sleep Medicine, University of Southern California, Los Angeles, CA. 15Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, Columbus, OH. 16Department of Surgery, University of Arizona, Tucson, AZ. 17Division of Acute Care Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI. 18Department of Anesthesiology and Critical Care Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY. 19Department of Surgery, Division of Thoracic Surgery, Division of Trauma, Burn & Critical Care, Brigham and Women's Hospital, Boston, MA. 20Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY. 21INOVA Fairfax Hospital, Falls Church, VA. 22Suburban Hospital, Bethesda, MD. 23Department of A

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October 2015

Pharmacist leadership in ICU quality improvement: coordinating spontaneous awakening and breathing trials.

Ann Pharmacother 2015 Aug 23;49(8):883-91. Epub 2015 Apr 23.

Vanderbilt University School of Medicine Nashville, TN, USA.

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August 2015

Functional brain imaging in survivors of critical illness: A prospective feasibility study and exploration of the association between delirium and brain activation patterns.

J Crit Care 2015 Jun 30;30(3):653.e1-7. Epub 2015 Jan 30.

Department of Psychology, Brigham Young University, Provo, UT; Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center, Murray UT; Neuroscience Center, Brigham Young University, Provo, UT.

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http://dx.doi.org/10.1016/j.jcrc.2015.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489139PMC
June 2015

Burst suppression on processed electroencephalography as a predictor of postcoma delirium in mechanically ventilated ICU patients.

Crit Care Med 2014 Oct;42(10):2244-51

1Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA. 2Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN. 3Center for Health Services Research, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN. 4Geriatric Research, Education, and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 5Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 6Division of Critical Care, Department of Anesthesia, Vanderbilt University Medical Center, Nashville, TN. 7Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1097/CCM.0000000000000522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493889PMC
October 2014

Statins and delirium during critical illness: a multicenter, prospective cohort study.

Crit Care Med 2014 Aug;42(8):1899-909

1Rehabilitation and Aged Care Unit, Hospital Ancelle, Cremona, Italy. 2Geriatric Research Group, Brescia, Italy. 3Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN. 4Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN. 5Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 6Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN. 7Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN. 8Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 9Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 10Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, TN. 11Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 12Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN. 13Research Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 14Division of Neurology, Department of Medicine, Department of Anesthesiology, and Department of Neurobiology, Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1097/CCM.0000000000000398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103957PMC
August 2014

Sedative choice: a critical decision.

Am J Respir Crit Care Med 2014 Jun;189(11):1295-7

1 Department of Medicine Vanderbilt University School of Medicine Nashville, Tennessee.

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June 2014

Only a small subset of sedation-related delirium is innocuous: we cannot let our guard down.

Am J Respir Crit Care Med 2014 Jun;189(11):1443-4

1 Vanderbilt University School of Medicine Nashville, Tennessee and.

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June 2014

Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study.

Lancet Respir Med 2014 May 7;2(5):369-79. Epub 2014 Apr 7.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA; Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.

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http://dx.doi.org/10.1016/S2213-2600(14)70051-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107313PMC
May 2014

Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.

Crit Care Med 2014 Feb;42(2):344-56

1Division of Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD. 2Division of Pulmonary, Allergy, and Critical Care, Emory University, Atlanta, GA. 3Division of Pulmonary and Critical Care, Intermountain Medical Center and University of Utah, Salt Lake City, UT. 4Division of Pulmonary and Critical Care, University of Medicine and Dentistry of New Jersey, Newark, NJ. 5Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri-Columbia, Columbia, MO. 6Division of Pulmonary and Critical Care, Meharry Medical College, Nashville, TN. 7Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN. 8Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA. 9Department of Surgical Critical Care, University of Maryland, Baltimore, MD. 10Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, Cleveland, OH. 11Division of Acute Care Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI. 12Department of Anesthesiology and Critical Care Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY. 13Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA. 14Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY. 15INOVA Fairfax Hospital, Falls Church, VA. 16Suburban Hospital, Bethesda, MD. 17Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, CT. 18Department of Anesthesia, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0b013e3182a275d7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035482PMC
February 2014

Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation.

Crit Care Med 2014 Feb;42(2):369-77

1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 2Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 3Center for Quality of Aging, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 4Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 5Department of Psychiatry, Vanderbilt Medical Center, Nashville, TN. 6Clinical Research Center of Excellence, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 7Division of Critical Care, Department of Anesthesiology, Vanderbilt School of Medicine, Nashville, TN. 8Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 9Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN. 10Institute for Medicine and Public Heath, Vanderbilt University School of Medicine, Nashville, TN. 11Department of Internal Medicine, Yale School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1097/CCM.0b013e3182a645bdDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947028PMC
February 2014

Long-term cognitive impairment after critical illness.

N Engl J Med 2014 01;370(2):185-6

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January 2014

Daily sedation interruption versus targeted light sedation strategies in ICU patients.

Crit Care Med 2013 Sep;41(9 Suppl 1):S39-45

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1097/CCM.0b013e3182a168c5DOI Listing
September 2013

Association between endothelial dysfunction and acute brain dysfunction during critical illness.

Anesthesiology 2013 Mar;118(3):631-9

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, 1211 21st Ave. South, 526 MAB, Nashville, Tennessee 37212, USA.

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http://dx.doi.org/10.1097/ALN.0b013e31827bd193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580006PMC
March 2013

Preventing delirium in the intensive care unit.

Crit Care Clin 2013 Jan;29(1):51-65

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.ccc.2012.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508697PMC
January 2013

A combined early cognitive and physical rehabilitation program for people who are critically ill: the activity and cognitive therapy in the intensive care unit (ACT-ICU) trial.

Phys Ther 2012 Dec 10;92(12):1580-92. Epub 2012 May 10.

Division of Allergy, Pulmonary, and Critical Care Medicine and Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37212, USA.

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http://dx.doi.org/10.2522/ptj.20110414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513484PMC
December 2012

Markers of inflammation and coagulation may be modulated by enteral feeding strategy.

JPEN J Parenter Enteral Nutr 2012 Nov 7;36(6):732-40. Epub 2012 Feb 7.

Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2650, USA.

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http://dx.doi.org/10.1177/0148607111433054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726194PMC
November 2012

Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium.

Crit Care Med 2012 Oct;40(10):2788-96

Department of Critical Care and Emergency Medicine and The CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute illness) Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e31825b8adeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576216PMC
October 2012

Future directions of delirium research and management.

Best Pract Res Clin Anaesthesiol 2012 Sep;26(3):395-405

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.bpa.2012.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638881PMC
September 2012

Are we sedating more than just the brain?

Crit Care 2011 7;15(3):163. Epub 2011 Jun 7.

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, 1215, 21st Avenue South, Medical Center East, 6th Floor, Suite 6000, Nashville, TN 37232-8300, USA.

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http://dx.doi.org/10.1186/cc10233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218986PMC
August 2012

Point: should benzodiazepines be avoided in mechanically ventilated patients? Yes.

Chest 2012 Aug;142(2):281-284

Division of Allergy, Pulmonary, and Critical Care Medicine, Nashville, TN; Center for Health Services Research, Nashville, TN.

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http://dx.doi.org/10.1378/chest.12-1189DOI Listing
August 2012

Medical and economic implications of cognitive and psychiatric disability of survivorship.

Semin Respir Crit Care Med 2012 Aug 8;33(4):348-56. Epub 2012 Aug 8.

Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center, Murray, UT 84107, USA.

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http://dx.doi.org/10.1055/s-0032-1321984DOI Listing
August 2012

Brain dysfunction in patients with chronic critical illness.

Authors:
Timothy D Girard

Respir Care 2012 Jun;57(6):947-55; discussion 955-7

Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-8300, USA.

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http://dx.doi.org/10.4187/respcare.01708DOI Listing
June 2012

The bedside diagnosis of ICU delirium: specificity is high, let's optimize sensitivity.

Am J Respir Crit Care Med 2012 Jan;185(1):107-8; author reply 108

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January 2012

Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients.

Crit Care 2011 2;15(2):R78. Epub 2011 Mar 2.

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, 526 MAB, 1211 21st Ave South, Nashville, TN 37212, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219330PMC
December 2011

Sedation and weaning from mechanical ventilation: linking spontaneous awakening trials and spontaneous breathing trials to improve patient outcomes.

Anesthesiol Clin 2011 Dec;29(4):651-61

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Center for Health Services Research, Vanderbilt University School of Medicine, 6th Floor MCE, #6100, Nashville, TN 37232-8300, USA.

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December 2011

Statins and brain dysfunction: a hypothesis to reduce the burden of cognitive impairment in patients who are critically ill.

Chest 2011 Sep;140(3):580-585

Department of Anesthesiology, Division of Critical Care Medicine, Vanderbilt University School of Medicine; Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.

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http://dx.doi.org/10.1378/chest.10-3065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168859PMC
September 2011

The complex interplay between delirium, sedation, and early mobility during critical illness: applications in the trauma unit.

Curr Opin Anaesthesiol 2011 Apr;24(2):195-201

Department of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1097/ACO.0b013e3283445382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606927PMC
April 2011

A screening, prevention, and restoration model for saving the injured brain in intensive care unit survivors.

Crit Care Med 2010 Oct;38(10 Suppl):S683-91

Center for Health Services Research, Department of Medicine, Vanderbilt School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1097/CCM.0b013e3181f245d3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679543PMC
October 2010

Communication in critical care: family rounds in the intensive care unit.

Am J Crit Care 2010 Sep;19(5):421-30

Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-8300, USA.

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http://dx.doi.org/10.4037/ajcc2010656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707491PMC
September 2010

Neuroimaging in delirious intensive care unit patients: a preliminary case series report.

Psychiatry (Edgmont) 2010 Sep;7(9):28-33

Center for Health Services Research Center, Vanderbilt Center for Quality of Aging, Nashville, Tennesee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952644PMC
September 2010

Delirium as a predictor of long-term cognitive impairment in survivors of critical illness.

Crit Care Med 2010 Jul;38(7):1513-20

Division of Allergy, Pulmonary, and Critical Care Medicine, Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, and Department of Medicine, Saint Thomas Hospital, Nashville, TN, USA.

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http://dx.doi.org/10.1097/CCM.0b013e3181e47be1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638813PMC
July 2010