Publications by authors named "Timothy C Greiner"

100Publications

Radiologic Differentiation of Primary CNS Posttransplant Lymphoproliferative Disorder From Brain Metastasis.

AJR Am J Roentgenol 2020 07 29;215(1):184-191. Epub 2020 Apr 29.

Department of Pathology, University of Nebraska Medical Center, Omaha, NE.

View Article and Find Full Text PDF
July 2020

Primary central nervous system post-transplant lymphoproliferative disorders: the spectrum of imaging appearances and differential.

Insights Imaging 2019 Apr 11;10(1):46. Epub 2019 Apr 11.

Oncology, University of Nebraska Medical Center, 986840 Nebraska Medical Center, Omaha, NE, 68198-6840, USA.

View Article and Find Full Text PDF
April 2019

Rac1 is a novel therapeutic target in mantle cell lymphoma.

Blood Cancer J 2018 02 12;8(2):17. Epub 2018 Feb 12.

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.

View Article and Find Full Text PDF
February 2018

Rituximab Improves the Outcome of Patients With Grade 3 Follicular Lymphoma Receiving Anthracycline-Based Therapy.

Clin Lymphoma Myeloma Leuk 2017 08 16;17(8):488-497.e2. Epub 2017 Jun 16.

Department of Pathology, City of Hope National Medical Center, Duarte, CA. Electronic address:

View Article and Find Full Text PDF
August 2017

New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies.

J Clin Oncol 2017 May 14;35(15):1668-1677. Epub 2017 Mar 14.

David W. Scott, Pau Abrisqueta, Graham W. Slack, Anja Mottok, Diego Villa, Merrill Boyle, Fong Chun Chan, Christian Steidl, Joseph M. Connors, and Randy D. Gascoyne, BC Cancer Agency; Anja Mottok, Christian Steidl, and Randy D. Gascoyne, University of British Columbia, Vancouver, British Columbia; Jan Delabie, University of Toronto, Toronto, Ontario, Canada; Pau Abrisqueta, Vall d'Hebron University Hospital; Pedro Jares, Cristina Royo, Guillem Clot, Magda Pinyol, and Elias Campo, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; George W. Wright, Elaine S. Jaffe, and Louis M. Staudt, National Institutes of Health, Bethesda, MD; Hilka Rauert-Wunderlich and Andreas Rosenwald, University of Würzburg, Würzburg; German Ott, Robert Bosch Hospital and Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; Rita M. Braziel, Oregon Health & Sciences University, Portland, OR; Wing C. Chan and Dennis D. Weisenburger, City of Hope, Duarte, CA; James R. Cook, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH; Timothy C. Greiner and Kai Fu, University of Nebraska Medical Center, Omaha, NE; Erlend B. Smeland and Harald Holte, Oslo University Hospital, Oslo, Norway; and Lisa M. Rimsza, Mayo Clinic, Phoenix, AZ.

View Article and Find Full Text PDF
May 2017

Identification of Primary Mediastinal Large B-cell Lymphoma at Nonmediastinal Sites by Gene Expression Profiling.

Am J Surg Pathol 2015 Oct;39(10):1322-30

*Department of Pathology and Microbiology ¶Department of Biostatistics, College of Public Health ##Department of Hematology/Oncology, University of Nebraska Medical Center, Omaha, NE †Metabolism Branch **Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD ∥Department of Pathology, City of Hope National Medical Center, Duarte, CA #Department of Pathology, University of Arizona, Tucson, AZ §§Department of Clinical Pathology, Oregon Health and Science University, Portland, OR ∥∥Department of Molecular Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH ‡Institute of Pathology, Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg ¶¶Department of Clinical Pathology, Robert-Bosch-Krankenhaus, Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany §British Columbia Cancer Agency, Centre for Lymphoid Cancer, University of British Columbia, Vancouver, BC, Canada ††Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain ‡‡Department of Pathology, The Norwegian Radium Hospital, University of Oslo, Oslo, Norway.

View Article and Find Full Text PDF
October 2015

Leukemic diffuse large B-cell lymphoma in a patient with myeloproliferative disorder.

J Natl Compr Canc Netw 2015 Mar;13(3):281-7

From the Department of Internal Medicine, Division of Hematology-Oncology; Department of Pathology and Microbiology; and Human Genetics Laboratory, Munroe Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska.

View Article and Find Full Text PDF
March 2015

EZH2 mutations in follicular lymphoma from different ethnic groups and associated gene expression alterations.

Clin Cancer Res 2014 Jun 14;20(12):3078-86. Epub 2014 Mar 14.

Authors' Affiliations: Department of Pathology, Xi Jing Hospital, the Fourth Military Medical University, Xi'an, Shaan Xi Province; Department of Pathology, Queen Elizabeth Hospital, Hong Kong; Department of Pathology, Shandong University School of Medicine, Jinan, Shandong Province; Department of Pathology, Tianjin Cancer Hospital; Department of Pathology, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China; and Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska

View Article and Find Full Text PDF
June 2014

Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP.

J Clin Oncol 2013 Dec 12;31(36):4520-8. Epub 2013 Nov 12.

Xin Huang, Bin Meng, Wenfeng Cao, and Kai Fu, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin; Chengfeng Bi, West China Hospital, West China School of Medicine of Sichuan University, Chengdu, China; Xin Huang, Bin Meng, Javeed Iqbal, Anamarija M. Perry, Wenfeng Cao, Lynette M. Smith, Chengfeng Bi, Chunsun Jiang, Timothy C. Greiner, Dennis D. Weisenburger, James O. Armitage, Julie M. Vose, Timothy W. McKeithan, Wing C. Chan, and Kai Fu, University of Nebraska Medical Center, Omaha, NE; B. Belinda Ding and B. Hilda Ye, Albert Einstein College of Medicine, Bronx, NY; Lisa Rimsza, University of Arizona, Tucson, AZ; Andreas Rosenwald, University of Würzburg, Würzburg, Germany; German Ott and Jan Delabie, Rikshospitalet-Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway; Elias Campo, Hospital Clinic, University of Barcelona, Barcelona, Spain; Rita M. Braziel, Oregon Health and Science University, Portland, OR; Randy D. Gascoyne, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; James R. Cook and Raymond R. Tubbs, Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH; Elaine S. Jaffe and Louis M. Staudt, Center for Cancer Research, National Cancer Institute, Bethesda, MD.

View Article and Find Full Text PDF
December 2013

Autoimmune neutropenia in multiple myeloma and the role of clonal T-cell expansion: evidence of cross-talk between B-cell and T-cell lineages?

Clin Lymphoma Myeloma Leuk 2014 Feb 30;14(1):e19-23. Epub 2013 Oct 30.

Department of Internal Medicine, Division of Hematology-Oncology, University of Nebraska Medical Center, Omaha, NE. Electronic address:

View Article and Find Full Text PDF
February 2014

Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology.

J Mol Diagn 2013 Nov 24;15(6):733-44. Epub 2013 Aug 24.

JAK2 Mutation Working Group, Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address:

View Article and Find Full Text PDF
November 2013

Comparison study of the performance of the QIAGEN EGFR RGQ and EGFR pyro assays for mutation analysis in non-small cell lung cancer.

Am J Clin Pathol 2013 Jul;140(1):7-19

Dept of Pathology and Microbiology, University of Nebraska Medical Center, 985454 Nebraska Medical Center, Omaha, NE 68105-5454, USA.

View Article and Find Full Text PDF
July 2013

Cytogenetic abnormalities in follicular dendritic cell sarcoma: report of two cases and literature review.

In Vivo 2013 Mar-Apr;27(2):211-4

Department of Pathology, University of Manitoba, Health Sciences Centre, Winnipeg, MB, Canada.

View Article and Find Full Text PDF
August 2013

Investigation of the BRAF V600E mutation by pyrosequencing in lymphoproliferative disorders.

Am J Clin Pathol 2012 Dec;138(6):877-83

Dept of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68195, USA.

View Article and Find Full Text PDF
December 2012

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies.

Blood 2012 Apr 24;119(16):3668-83. Epub 2012 Jan 24.

Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, USA.

View Article and Find Full Text PDF
April 2012

Extranodal marginal zone lymphoma of the dura mater with IgH/MALT1 translocation and review of literature.

J Hematop 2008 Sep 18;1(2):131-7. Epub 2008 Jun 18.

Department of Anatomic Pathology, William Beaumont Hospital, Royal Oak, MI, 48076, USA.

View Article and Find Full Text PDF
September 2008

Membrane-type 1 matrix metalloproteinase regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo.

J Biol Chem 2009 Jan 14;284(3):1765-71. Epub 2008 Nov 14.

Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska, 68198, USA.

View Article and Find Full Text PDF
January 2009

Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma.

Mol Cancer Ther 2008 Jun 4;7(6):1450-60. Epub 2008 Jun 4.

Department of Genetics, Cell Biology, and Anatomy, Center for Research in Leukemia and Lymphoma, University of Nebraska Medical Center, Omaha, NE 68198-6395, USA.

View Article and Find Full Text PDF
June 2008

Implementation of a T4 extraction control for molecular assays of cerebrospinal fluid and stool specimens.

J Mol Diagn 2008 Jan 28;10(1):28-32. Epub 2007 Dec 28.

Department of Pathology and Microbiology, University of Nebraska Medical Center, College of Medicine, Omaha, Nebraska 68198-5454, USA.

View Article and Find Full Text PDF
January 2008

Enhanced detection of TP53 mutations using a GC-clamp in denaturing high performance liquid chromatography.

Diagn Mol Pathol 2007 Mar;16(1):32-7

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135, USA.

View Article and Find Full Text PDF
March 2007

Mantle cell lymphoma with plasma cell differentiation.

Am J Surg Pathol 2006 Aug;30(8):954-61

Department of Pathology and Laboratory Medicine, University of Wisconsin Hospital and Clinics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

View Article and Find Full Text PDF
August 2006

mRNA microarray analysis in lymphoma and leukemia.

Cancer Treat Res 2004 ;121:1-12

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.

View Article and Find Full Text PDF
July 2004

Key roles of CD4+ T cells and IFN-gamma in the development of abdominal aortic aneurysms in a murine model.

J Immunol 2004 Feb;172(4):2607-12

Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article and Find Full Text PDF
February 2004

Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells.

Am J Pathol 2003 Jul;163(1):135-44

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska and The Metabolism Branch, National Cancer Institute, Bethesda, Maryland, USA.

View Article and Find Full Text PDF
July 2003

The distribution of gene segments in T-cell receptor gamma gene rearrangements demonstrates the need for multiple primer sets.

J Mol Diagn 2003 May;5(2):82-7

Department of Pathology and Microbiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, Nebraska 68198, USA.

View Article and Find Full Text PDF
May 2003

Oligonucleotide microarrays demonstrate the highest frequency of ATM mutations in the mantle cell subtype of lymphoma.

Proc Natl Acad Sci U S A 2003 Apr 15;100(9):5372-7. Epub 2003 Apr 15.

Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article and Find Full Text PDF
April 2003

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.

EMBO J 2003 Mar;22(6):1442-50

Eppley Institute for Cancer Research, Department of Pathology and Microbiology, 987696 University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article and Find Full Text PDF
March 2003

Removal of mercuric chloride deposits from B5-fixed tissue will affect the performance of immunoperoxidase staining of selected antibodies.

Appl Immunohistochem Mol Morphol 2003 Mar;11(1):92-5

Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198-3135, USA.

View Article and Find Full Text PDF
March 2003