Timothy A McCaffrey

Timothy A McCaffrey

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Timothy A McCaffrey

Timothy A McCaffrey

Publications by authors named "Timothy A McCaffrey"

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37Publications

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Benchmark Evaluation of True Single Molecular Sequencing to Determine Cystic Fibrosis Airway Microbiome Diversity.

Front Microbiol 2018 25;9:1069. Epub 2018 May 25.

Computational Biology Institute, Milken Institute School of Public Health, The George Washington University, Washington, DC, United States.

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May 2018

Predictors of high on-aspirin platelet reactivity in elderly patients with coronary artery disease.

Clin Interv Aging 2017 10;12:1271-1279. Epub 2017 Aug 10.

Department of Geriatrics, Peking University First Hospital, Beijing, China.

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March 2018

An efficient concordant integrative analysis of multiple large-scale two-sample expression data sets.

Bioinformatics 2017 Dec;33(23):3852-3860

Division of Genomic Medicine, Department of Medicine, The George Washington University Medical Center, Washington, DC 20037, USA.

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December 2017

Validation of aspirin response-related transcripts in patients with coronary artery disease and preliminary investigation on CMTM5 function.

Gene 2017 Aug 28;624:56-65. Epub 2017 Apr 28.

Department of Geriatrics, Peking University First Hospital, Beijing, China. Electronic address:

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August 2017

Detecting discordance enrichment among a series of two-sample genome-wide expression data sets.

BMC Genomics 2017 01 25;18(Suppl 1):1050. Epub 2017 Jan 25.

Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, 20037, D.C., USA.

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January 2017

Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes.

BMC Med Genomics 2016 07 15;9(1):40. Epub 2016 Jul 15.

Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, 2300 I Street, NW Ross 443, Washington, DC, 20037, USA.

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July 2016

Functional annotation of the vlinc class of non-coding RNAs using systems biology approach.

Nucleic Acids Res 2016 Apr 21;44(7):3233-52. Epub 2016 Mar 21.

Institute of Genomics, School of Biomedical Sciences, Huaqiao University, 668 Jimei Road, Xiamen 361021, China St. Laurent Institute, 317 New Boston St., Suite 201, Woburn, MA 01801, USA

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April 2016

Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events.

J Am Coll Cardiol 2013 Oct 3;62(14):1267-1276. Epub 2013 Jul 3.

Institute for Genome Sciences & Policy, Duke University, Durham, North Carolina; Department of Medicine, Duke University, Durham, North Carolina. Electronic address:

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October 2013

On the importance of small changes in RNA expression.

Methods 2013 Sep 4;63(1):18-24. Epub 2013 Apr 4.

Immunovirology - Biogenisis Group, University of Antioquia, A.A. 1226, Medellin, Colombia; St. Laurent Institute, One Kendall Square, Cambridge, MA, USA. Electronic address:

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September 2013

Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity.

Int J Biol Sci 2013 22;9(4):350-60. Epub 2013 Apr 22.

Department of Medicine, Division of Genomic Medicine, George Washington University School of Medicine and Health Sciences, Washington DC, USA.

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September 2013

Role of deregulated microRNAs in breast cancer progression using FFPE tissue.

PLoS One 2013 23;8(1):e54213. Epub 2013 Jan 23.

Division of Genomic Medicine, Department of Medicine, The George Washington University School of Medicine and Health Sciences, Washington, District of Colombia, United States of America.

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July 2013

Transforming growth factor-β and atherosclerosis: interwoven atherogenic and atheroprotective aspects.

Cell Tissue Res 2012 Jan 31;347(1):155-75. Epub 2011 May 31.

Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, 2300 I Street NW. Ross Hall 443, Washington, DC 20037, USA.

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January 2012

Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells.

J Biol Chem 2011 Aug 6;286(31):27389-98. Epub 2011 Jun 6.

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, USA.

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August 2011

Beyond genetics: epigenetic code in chronic kidney disease.

Kidney Int 2011 Jan 29;79(1):23-32. Epub 2010 Sep 29.

Division of Renal Diseases and Hypertension, The George Washington University, Washington, District of Columbia 20037, USA.

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January 2011

BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer.

Int J Biol Sci 2010 Sep 10;6(5):513-24. Epub 2010 Sep 10.

Department of Medicine, Division of Genomic Medicine, George Washington University Medical Center, Washington, DC, USA.

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September 2010

BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer.

J Cancer 2010 Jun 24;1:54-62. Epub 2010 Jun 24.

1. Department of Medicine, Division of Genomic Medicine, George Washington University Medical Center, Washington, DC, USA.

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June 2010

A LINE-1 component to human aging: do LINE elements exact a longevity cost for evolutionary advantage?

Mech Ageing Dev 2010 May 25;131(5):299-305. Epub 2010 Mar 25.

The George Washington University Medical Center, Department of Medicine, Division of Genomic Medicine, 2300 I St. NW, Washington, DC 20037, United States.

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May 2010

Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the interferon-inducible immunoproteasome.

Arterioscler Thromb Vasc Biol 2009 Aug 14;29(8):1213-9. Epub 2009 May 14.

The George Washington Medical Center, Department of Biochemistry and Molecular Biology, 2300 I Street NW, Ross Hall 541, Washington, DC 20037, USA.

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August 2009

TGF-beta signaling in atherosclerosis and restenosis.

Front Biosci (Schol Ed) 2009 Jun 1;1:236-45. Epub 2009 Jun 1.

The George Washington University Medical Center, Department of Biochemistry and Molecular Biology, The Catharine Birch McCormick Genomics Center, and The Richard B. and Lynne V. Cheney Cardiovascular Institute, Washington, D.C. USA.

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June 2009

Resistance to fas-induced apoptosis in cells from human atherosclerotic lesions: elevated Bcl-XL inhibits apoptosis and caspase activation.

J Vasc Res 2007 26;44(6):483-94. Epub 2007 Jul 26.

Department of Biochemistry and Molecular Biology, George Washington University Medical Center, Washington, DC 20037, USA.

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November 2007

Meta-analysis of microarray results: challenges, opportunities, and recommendations for standardization.

Gene 2007 Oct 3;401(1-2):12-8. Epub 2007 Jul 3.

Department of Internal Medicine, Washington University, St. Louis, MO 63110, USA.

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October 2007

List of lists-annotated (LOLA): a database for annotation and comparison of published microarray gene lists.

Gene 2005 Oct 2;360(1):78-82. Epub 2005 Sep 2.

The George Washington University Medical Center, Department of Biochemistry and Molecular Biology, 2300 I Street NW. Ross Hall 541, Washington, D.C. 20037, United States.

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October 2005

Genomic profiling of acquired resistance to apoptosis in cells derived from human atherosclerotic lesions: potential role of STATs, cyclinD1, BAD, and Bcl-XL.

J Mol Cell Cardiol 2005 Sep;39(3):453-65

The George Washington University Medical Center, Department of Biochemistry and Molecular Biology, Washington, DC 20037, USA.

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September 2005

SCID repopulating cells derived from unmobilised adult human peripheral blood.

Curr Med Res Opin 2004 Jan;20(1):87-100

TriStem UK Limited, 571 Finchley Road, Unit 320, London NW3 7BN, UK.

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January 2004

Does metabolic radiolabeling stimulate the stress response? Gene expression profiling reveals differential cellular responses to internal beta vs. external gamma radiation.

FASEB J 2003 Aug;17(11):1470-86

Department of Biochemistry and Molecular Biology, The George Washington University Medical Center, 2300 Eye St., N.W., Washington, DC 20037, USA.

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August 2003

Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression.

J Biol Chem 2002 Apr 4;277(16):13778-86. Epub 2002 Feb 4.

Department of Pathology, Joan and Sanford I. Weill Medical College of Cornell University, New York, New York 10021, USA.

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April 2002