Timo Grimmer

Timo Grimmer

UNVERIFIED PROFILE

Are you Timo Grimmer?   Register this Author

Register author
Timo Grimmer

Timo Grimmer

Publications by authors named "Timo Grimmer"

Are you Timo Grimmer?   Register this Author

100Publications

2703Reads

41Profile Views

Increasing Diagnostic Accuracy of Mild Cognitive Impairment due to Alzheimer's Disease by User-Independent, Web-Based Whole-Brain Volumetry.

J Alzheimers Dis 2018 ;65(4):1459-1467

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-180532DOI Listing
August 2019

Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer's disease and associated with CSF-TAU and FDG-PET.

Transl Neurodegener 2019 27;8:25. Epub 2019 Aug 27.

1Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Ismaninger Str. 22, 81675 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40035-019-0168-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712703PMC
August 2019

Reduced blood oxygenation level dependent connectivity is related to hypoperfusion in Alzheimer's disease.

J Cereb Blood Flow Metab 2019 Jul 12;39(7):1314-1325. Epub 2018 Feb 12.

1 Department of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0271678X18759182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668525PMC
July 2019

Associations of Neprilysin Activity in CSF with Biomarkers for Alzheimer's Disease.

Neurodegener Dis 2019 2;19(1):43-50. Epub 2019 Jul 2.

Dementia Research Group, School of Clinical Sciences, University of Bristol, Southmead Hospital, Bristol, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000500811DOI Listing
July 2019

An augmented reality approach for ADL support in Alzheimer's disease: a crossover trial.

J Neuroeng Rehabil 2019 Jun 3;16(1):66. Epub 2019 Jun 3.

Chair of Human Movement Science, Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12984-019-0530-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547460PMC
June 2019

Functional Decline in Alzheimer's Disease: A Continuum.

J Am Geriatr Soc 2018 12 21;66(12):2239-2240. Epub 2018 Nov 21.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.15668DOI Listing
December 2018

Cerebrospinal Fluid BACE1 Activity and sAβPPβ as Biomarker Candidates of Alzheimer's Disease.

Dement Geriatr Cogn Disord 2018 22;45(3-4):152-161. Epub 2018 May 22.

Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000488481DOI Listing
November 2018

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Ann Neurol 2018 11;84(5):729-740

Alzheimer center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354051PMC
November 2018

Rate of β-amyloid accumulation varies with baseline amyloid burden: Implications for anti-amyloid drug trials.

Alzheimers Dement 2018 11 4;14(11):1387-1396. Epub 2018 Jul 4.

Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; Neuroimaging Center (TUM-NIC), Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15525260183021
Publisher Site
http://dx.doi.org/10.1016/j.jalz.2018.05.013DOI Listing
November 2018

Correction: F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases.

Mol Psychiatry 2018 Nov 21. Epub 2018 Nov 21.

Department of Nuclear Medicine, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-018-0302-3DOI Listing
November 2018

Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Neurology 2018 10 12;91(15):e1390-e1401. Epub 2018 Sep 12.

From the Department of Neurology (P.S., S.A.-S., E.S., I.U., C.A.F.v.A., J. Kassubek, B.L., P.O., A.C.L., M.O.) and Institute of Epidemiology and Medical Biometry (B.M.), University of Ulm; Department of Psychiatry and Psychotherapy (J.D.-S., H.F., T.G.), Klinikum Rechts der Isar, Technical University of Munich; Department of Nuclear Medicine (H.B.), Leipzig University Hospital; Department of Neurology (A.D.), Ludwig-Maximilians-University, Munich; Department of Neurology (K.F.), Saarland University, Homburg; Department of Psychiatry and Psychotherapy (K.F.), University of Bonn, Germany; Swiss Epilepsy Center (H.-J.H.), Zurich, Switzerland; Department of Psychiatry and Psychotherapy (H.J.), University Medical Center Hamburg-Eppendorf, Hamburg; AMEOS Klinikum (H.J.), Heiligenhafen; Department of Psychiatry and Psychotherapy (J. Kornhuber, J.M.M.), Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen; Department of Psychiatry and Psychotherapy (M.L.), University of Würzburg; Department of Neurology (J.P.), University of Rostock; DZNE (J.P.), Rostock; Department of Neurodegenerative Diseases and Geriatric Psychiatry (A.S.), University Hospital Bonn; DZNE (A.S.), Bonn; Institute of Human Genetics (A.E.V.), University Medical Center Hamburg-Eppendorf, Hamburg; Department of Psychiatry and Psychotherapy (J.W.), University Medical Center Göttingen; DZNE (J.W.), Göttingen, Germany; iBiMED (J.W.), Medical Sciences Department, University of Aveiro, Portugal; Clinic for Cognitive Neurology (M.L.S.), University Clinic Leipzig; and Max Planck Institute for Human Cognitive and Brain Sciences (M.L.S.), Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000006318DOI Listing
October 2018

Plasma levels of soluble amyloid precursor protein β in symptomatic Alzheimer's disease.

Eur Arch Psychiatry Clin Neurosci 2018 Aug 10;268(5):519-524. Epub 2017 Jun 10.

Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00406-017-0815-9DOI Listing
August 2018

F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases.

Mol Psychiatry 2018 Aug 17. Epub 2018 Aug 17.

Department of Nuclear Medicine, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41380-018-0203-5
Publisher Site
http://dx.doi.org/10.1038/s41380-018-0203-5DOI Listing
August 2018

An Explorative Note on Apraxia Tests.

Front Neurol 2018 8;9:660. Epub 2018 Aug 8.

Chair of Human Movement Science, Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2018.00660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092500PMC
August 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach.

J Proteomics 2018 06 22;182:12-20. Epub 2018 Apr 22.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Department of Pathology & Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada; Department of Clinical Biochemistry, University Health Network, Toronto, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jprot.2018.04.027DOI Listing
June 2018

Fluid biomarker agreement and interrelation in dementia due to Alzheimer's disease.

J Neural Transm (Vienna) 2018 02 15;125(2):193-201. Epub 2017 Nov 15.

Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Nussbaumstraße 7, 80336, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00702-017-1810-zDOI Listing
February 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 01;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer's disease.

Sci Rep 2017 10 10;7(1):12906. Epub 2017 Oct 10.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-13349-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635105PMC
October 2017

Resting-State Networks as Simultaneously Measured with Functional MRI and PET.

J Nucl Med 2017 08 2;58(8):1314-1317. Epub 2017 Mar 2.

Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.116.185835DOI Listing
August 2017

Simultaneous object perception deficits are related to reduced visual processing speed in amnestic mild cognitive impairment.

Neurobiol Aging 2017 07 4;55:132-142. Epub 2017 Apr 4.

Department of General and Experimental Psychology, Ludwig-Maximilians-Universität München, Munich, Germany; Graduate School of Systemic Neurosciences, LMU, Munich, Germany; Hans Berger Department of Neurology, Jena University Hospital, Jena, Germany. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01974580173011
Publisher Site
http://dx.doi.org/10.1016/j.neurobiolaging.2017.03.029DOI Listing
July 2017

Predicting Regional Pattern of Longitudinal β-Amyloid Accumulation by Baseline PET.

J Nucl Med 2017 04 6;58(4):639-645. Epub 2016 Oct 6.

Department of Nuclear Medicine, University of Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.116.176115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373505PMC
April 2017

Metabolic connectivity for differential diagnosis of dementing disorders.

J Cereb Blood Flow Metab 2017 01 31;37(1):252-262. Epub 2015 Dec 31.

Department of Nuclear Medicine, Technische Universität München, Munich, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0271678X15622465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363743PMC
January 2017

Neuro-cognitive mechanisms of simultanagnosia in patients with posterior cortical atrophy.

Brain 2016 12 3;139(Pt 12):3267-3280. Epub 2016 Oct 3.

1 General and Experimental Psychology, Department of Psychology, Ludwig-Maximilians-Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://brain.oxfordjournals.org/content/brain/139/12/3267.fu
Web Search
http://dx.doi.org/10.1093/brain/aww235DOI Listing
December 2016

Mapping CSF biomarker profiles onto NIA-AA guidelines for Alzheimer's disease.

Eur Arch Psychiatry Clin Neurosci 2016 Oct 8;266(7):587-97. Epub 2015 Aug 8.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00406-015-0628-7DOI Listing
October 2016

Reduction of Amyloid-β Plasma Levels by Hemodialysis: An Anti-Amyloid Treatment Strategy?

J Alzheimers Dis 2016 ;50(3):791-6

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-150662DOI Listing
October 2016

Progressively Disrupted Intrinsic Functional Connectivity of Basolateral Amygdala in Very Early Alzheimer's Disease.

Front Neurol 2016 19;7:132. Epub 2016 Sep 19.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2016.00132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027206PMC
September 2016

Based on the Network Degeneration Hypothesis: Separating Individual Patients with Different Neurodegenerative Syndromes in a Preliminary Hybrid PET/MR Study.

J Nucl Med 2016 Mar 19;57(3):410-5. Epub 2015 Nov 19.

Department of Neuroradiology, Technische Universität München, Munich, Germany Department of Nuclear Medicine, Technische Universität München, Munich, Germany TUM-Neuroimaging Center (TUM-NIC), Technische Universität München, Munich, Germany Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.115.165464DOI Listing
March 2016

LRP-1 polymorphism is associated with global and regional amyloid load in Alzheimer's Disease in humans in-vivo.

Neuroimage Clin 2014 5;4:411-6. Epub 2014 Feb 5.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675 Munich, Germany ; Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology and Medicine, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2014.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939495PMC
February 2016

Metabolic connectivity mapping reveals effective connectivity in the resting human brain.

Proc Natl Acad Sci U S A 2016 Jan 28;113(2):428-33. Epub 2015 Dec 28.

Department of Neuroradiology, Klinikum rechts der Isar, Technischen Universitaet Muenchen, 81675 Muenchen, Germany; Neuroimaging Center, Klinikum Rechts der Isar, Technischen Universitaet Muenchen, 81675 Muenchen, Germany; Department of Psychiatry and Psychotherapy, Klinikum Rechts der Isar, Technischen Universitaet Muenchen, 81675 Muenchen, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1513752113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720331PMC
January 2016

Disrupted Intrinsic Networks Link Amyloid-β Pathology and Impaired Cognition in Prodromal Alzheimer's Disease.

Cereb Cortex 2015 Dec 4;25(12):4678-88. Epub 2014 Jul 4.

Department of Neuroradiology Department of Psychiatry Department of Nuclear Medicine TUM-Neuroimaging Center of Klinikum rechts der Isar, Technische Universität München (TUM), 81675 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cercor/bhu151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635914PMC
December 2015

Trends of patient referral to a memory clinic and towards earlier diagnosis from 1985-2009.

Int Psychogeriatr 2015 Dec 2;27(12):1939-44. Epub 2015 Oct 2.

Department of Psychiatry and Psychotherapy,Klinikum rechts der Isar der Technischen Universität München,Ismaninger Str. 22,81675 Munich,Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S104161021500157XDOI Listing
December 2015

Link between hippocampus' raised local and eased global intrinsic connectivity in AD.

Alzheimers Dement 2015 May 17;11(5):475-84. Epub 2014 Jul 17.

Department of Neuroradiology, Technische Universität München, Munich, Germany; TUM-Neuroimaging Center, Technische Universität München, Munich, Germany; Department of Psychiatry, Technische Universität München, Munich, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2014.02.007DOI Listing
May 2015

The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease.

Neurology 2015 May 15;84(19):1956-63. Epub 2015 Apr 15.

From the Departments of Neuroradiology (M.T., L.P., M. Scherr, C.M., S.M.B., V.R., C.S.), Nuclear Medicine (M.T., S.F., K.S., I.Y., M. Schwaiger, V.R., C.S., A.D.), and Psychiatry and Psychotherapy (M. Scherr, T.G., J.D.-S., C.S.) of Klinikum rechts der Isar, Technische Universität München; TUM-NIC Neuroimaging Center (M.T., L.P., M. Scherr, C.M., S.F., S.M.B., I.Y., V.R., C.S.), Technische Universität München, Munich; Graduate School of Systemic Neurosciences (C.M., S.M.B.), Ludwig Maximilians University, Munich; Department of Nuclear Medicine (M.T., A.D.), University Hospital of Cologne, Germany; Sleep Disorders Research Center (M.T.), Kermanshah University of Medical Sciences, Iran; and Department of Neurology (M. Scherr), Christian Doppler Clinic, Paracelsus Medical University, Salzburg, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000001575DOI Listing
May 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Authors:
Willemijn J Jansen Rik Ossenkoppele Dirk L Knol Betty M Tijms Philip Scheltens Frans R J Verhey Pieter Jelle Visser Pauline Aalten Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kristen Bibeau Kaj Blennow David J Brooks Mark A van Buchem Vincent Camus Enrica Cavedo Kewei Chen Gael Chetelat Ann D Cohen Alexander Drzezga Sebastiaan Engelborghs Anne M Fagan Tormod Fladby Adam S Fleisher Wiesje M van der Flier Lisa Ford Stefan Förster Juan Fortea Nadia Foskett Kristian S Frederiksen Yvonne Freund-Levi Giovanni B Frisoni Lutz Froelich Tomasz Gabryelewicz Kiran Dip Gill Olymbia Gkatzima Estrella Gómez-Tortosa Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Helmut Hildebrandt Lianna Ishihara Adrian Ivanoiu William J Jagust Peter Johannsen Ramesh Kandimalla Elisabeth Kapaki Aleksandra Klimkowicz-Mrowiec William E Klunk Sebastian Köhler Norman Koglin Johannes Kornhuber Milica G Kramberger Koen Van Laere Susan M Landau Dong Young Lee Mony de Leon Viviana Lisetti Alberto Lleó Karine Madsen Wolfgang Maier Jan Marcusson Niklas Mattsson Alexandre de Mendonça Olga Meulenbroek Philipp T Meyer Mark A Mintun Vincent Mok José Luis Molinuevo Hanne M Møllergård John C Morris Barbara Mroczko Stefan Van der Mussele Duk L Na Andrew Newberg Agneta Nordberg Arto Nordlund Gerald P Novak George P Paraskevas Lucilla Parnetti Gayan Perera Oliver Peters Julius Popp Sudesh Prabhakar Gil D Rabinovici Inez H G B Ramakers Lorena Rami Catarina Resende de Oliveira Juha O Rinne Karen M Rodrigue Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Christopher C Rowe Eckart Rüther Osama Sabri Páscual Sanchez-Juan Isabel Santana Marie Sarazin Johannes Schröder Christin Schütte Sang W Seo Femke Soetewey Hilkka Soininen Luiza Spiru Hanne Struyfs Charlotte E Teunissen Magda Tsolaki Rik Vandenberghe Marcel M Verbeek Victor L Villemagne Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Anders Wallin Åsa K Wallin Jens Wiltfang David A Wolk Marzena Zboch Henrik Zetterberg

JAMA 2015 May;313(19):1924-38

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden87UCL Institute of Neurology, Queen Square, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2015.4668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486209PMC
May 2015

Small vessel disease, but neither amyloid load nor metabolic deficit, is dependent on age at onset in Alzheimer's disease.

Biol Psychiatry 2015 Apr 31;77(8):704-10. Epub 2014 Jan 31.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsych.2014.01.019DOI Listing
April 2015

Risk of mild cognitive impairment: The Olmsted County MCI Risk Score.

Neurology 2015 Apr 18;84(14):1392-3. Epub 2015 Mar 18.

From the National Institute on Aging Intramural Research Program (A.B.Z.), National Institutes of Health, Baltimore, MD; and Department of Psychiatry and Psychotherapy (T.G.), Klinikum rechts der Isar, Technische Universität München, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000001452DOI Listing
April 2015

[New therapeutic approaches].

Ther Umsch 2015 Apr;72(4):279-85

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar; Technische Universität München.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/0040-5930/a000676DOI Listing
April 2015

FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice.

EJNMMI Res 2015 28;5:20. Epub 2015 Mar 28.

Department of Pharmaceutical Radiochemistry, Technische Universität München, Walther-Meißner-Str. 3, 85748 Garching, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13550-015-0090-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402683PMC
April 2015

Variability of cognitive performance during hemodialysis: standardization of cognitive assessment.

Dement Geriatr Cogn Disord 2014 20;38(1-2):31-8. Epub 2014 Feb 20.

Department of Nephrology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000357803DOI Listing
March 2015

Characterization and first human investigation of FIBT, a novel fluorinated Aβ plaque neuroimaging PET radioligand.

ACS Chem Neurosci 2015 Mar 8;6(3):428-37. Epub 2015 Jan 8.

†Department of Pharmaceutical Radiochemistry, ‡Department of Nuclear Medicine, and §Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cn5001827DOI Listing
March 2015

Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions.

J Nucl Med 2015 Mar 12;56(3):399-404. Epub 2015 Feb 12.

Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany Technische Universität München Neuroimaging Center (TUM-NIC), Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.114.149302DOI Listing
March 2015

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression.

Neurology 2015 Feb 7;84(5):508-15. Epub 2015 Jan 7.

From the Medical Imaging Unit (A.C.), Biomedical Engineering Department, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Bergamo; LENITEM-Laboratory of Epidemiology Neuroimaging and Telemedicine (A.P., S.G., C.F., A.R., G.B.F.), IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy; Alzheimer Center and Department of Neurology (W.M.v.d.F., R.O., P.S.), Department of Epidemiology & Biostatistics (W.M.v.d.F.), Department of Radiology & Nuclear Medicine (B.V.B., F.B.), and Neurochemistry Laboratorium and Biobank, Department of Clinical Chemistry (C.T.), VU University Medical Center, Amsterdam, the Netherlands; PET-Center (A.E.W.), Section of Nuclear Medicine & PET, Department of Radiology, Oncology and Radiation Sciences, Uppsala University; Alzheimer Neurobiology Center (S.F.C., M.S., I.H.C., A.N.), Karolinska Institutet, Stockholm, Sweden; Wolfson Molecular Imaging Centre (S.F.C.), University of Manchester, UK; MedTech West (M.S.), Sahlgrenska University Hospital, University of Gothenburg, Sweden; Department of Neuropsychiatry (I.H.C.), School of Medicine, Chosun University, Gwangju, Republic of Korea; Department of Psychiatry and Psychotherapy (T.G.), Klinikum rechts der Isar, Technische Universitat Muenchen, Germany; Department of Geriatric Medicine (A.N.), Karolinska University Hospital Huddinge, Stockholm, Sweden; Department of Nuclear Medicine (A.D.), University of Cologne, Germany; and Departments of Internal Medicine and Psychiatry (G.B.F.), University Hospitals and University of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://www.neurology.org/content/84/5/508.full.pdf
Web Search
http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000120
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000001209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336071PMC
February 2015

Limited agreement between biomarkers of neuronal injury at different stages of Alzheimer's disease.

Alzheimers Dement 2014 Nov 22;10(6):684-9. Epub 2014 May 22.

Department of Nuclear Medicine, Technische Universität München, Munich, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2014.03.006DOI Listing
November 2014

Efficacy of memantine hydrochloride once-daily in Alzheimer's disease.

Expert Opin Pharmacother 2014 Sep 1;15(13):1955-60. Epub 2014 Aug 1.

Technische Universität München, Klinikum rechts der Isar, Department of Psychiatry and Psychotherapy , Ismaninger Strasse 22, D-81675 Munich , Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14656566.2014.945907DOI Listing
September 2014

Within-patient correspondence of amyloid-β and intrinsic network connectivity in Alzheimer's disease.

Brain 2014 Jul 26;137(Pt 7):2052-64. Epub 2014 Apr 26.

1 Department of Neuroradiology, Technische Universität München, Ismaningerstr. 22, 81675 Munich, Germany2 TUM-Neuroimaging Centre, Technische Universität München, Ismaningerstr. 22, 81675 Munich, Germany4 Department of Psychiatry, Technische Universität München, Ismaningerstr. 22, 81675 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awu103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065018PMC
July 2014

Systematic Comparison of the Performance of Integrated Whole-Body PET/MR Imaging to Conventional PET/CT for ¹⁸F-FDG Brain Imaging in Patients Examined for Suspected Dementia.

J Nucl Med 2014 Jun 15;55(6):923-31. Epub 2014 May 15.

Department of Nuclear Medicine, Technische Universität München, Munich, Germany Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.113.126813DOI Listing
June 2014

In Alzheimer's disease, hypometabolism in low-amyloid brain regions may be a functional consequence of pathologies in connected brain regions.

Brain Connect 2014 Jun;4(5):371-83

1 Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München , Munich, Germany .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/brain.2013.0212DOI Listing
June 2014

Local activity determines functional connectivity in the resting human brain: a simultaneous FDG-PET/fMRI study.

J Neurosci 2014 Apr;34(18):6260-6

Departments of Neuroradiology, Nuclear Medicine, and Psychiatry, and Technische Universität München-Neuroimaging Center, Klinikum Rechts der Isar der Technischen Universität München, 81675 München, Germany, The Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, United Kingdom, and Department of Nuclear Medicine, Uniklinik Köln, 50937 Köln, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.0492-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608106PMC
April 2014

Amyloid cascade and tau pathology cerebrospinal fluid markers in mild cognitive impairment with regards to Alzheimer's disease cerebral metabolic signature.

J Alzheimers Dis 2013 ;36(2):401-8

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-122329DOI Listing
January 2014

Improving diagnosis of possible DLB: is there a role for MIBG myocardial scintigraphy?

Neurology 2013 Nov 11;81(20):1730-1. Epub 2013 Oct 11.

From the Wolfson Centre for Age Related Diseases (C.B.), King's College London, UK; and the Department of Psychiatry and Psychotherapy (T.G.), Klinikum Rechts der Isar, Technische Universitaet Muenchen, Munich, Germany.

View Article

Download full-text PDF

Source
http://www.neurology.org/cgi/doi/10.1212/01.wnl.0000435567.3
Publisher Site
http://dx.doi.org/10.1212/01.wnl.0000435567.38352.caDOI Listing
November 2013

The usefulness of amyloid imaging in predicting the clinical outcome after two years in subjects with mild cognitive impairment.

Curr Alzheimer Res 2013 Jan;10(1):82-5

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Mohlstr. 26, 81675 Munchen, Germany.

View Article

Download full-text PDF

Source
January 2013

White matter hyperintensities predict amyloid increase in Alzheimer's disease.

Neurobiol Aging 2012 Dec 10;33(12):2766-73. Epub 2012 Mar 10.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2012.01.016DOI Listing
December 2012

Interrelations between CSF soluble AβPPβ, amyloid-β 1-42, SORL1, and tau levels in Alzheimer's disease.

J Alzheimers Dis 2012 ;28(3):543-52

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-2011-110983DOI Listing
June 2012

Cerebrospinal fluid BACE1 activity and brain amyloid load in Alzheimer's disease.

ScientificWorldJournal 2012 3;2012:712048. Epub 2012 Jan 3.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Ismaninger Street 22, 81675 München, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1100/2012/712048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259508PMC
May 2012

Perfusion abnormalities in mild cognitive impairment and mild dementia in Alzheimer's disease measured by pulsed arterial spin labeling MRI.

Eur Arch Psychiatry Clin Neurosci 2012 Feb 24;262(1):69-77. Epub 2011 Jul 24.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der TU München, Ismaninger Str. 22, 81675, München, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00406-011-0226-2DOI Listing
February 2012

Age-related cerebral perfusion changes in the parietal and temporal lobes measured by pulsed arterial spin labeling.

J Magn Reson Imaging 2011 Dec 23;34(6):1295-302. Epub 2011 Sep 23.

Department of Neuroradiology, Technische Universität München, Munich, Germany; Department of Neurology, Technische Universität München, München, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jmri.22788DOI Listing
December 2011

Progression of cerebral amyloid load is associated with the apolipoprotein E ε4 genotype in Alzheimer's disease.

Biol Psychiatry 2010 Nov 2;68(10):879-84. Epub 2010 Jul 2.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Munich, Federal Republic of Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsych.2010.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045041PMC
November 2010

Clinical severity of Alzheimer's disease is associated with PIB uptake in PET.

Neurobiol Aging 2009 Dec 17;30(12):1902-9. Epub 2008 Mar 17.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2008.01.016DOI Listing
December 2009

Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid.

Biol Psychiatry 2009 Jun 6;65(11):927-34. Epub 2009 Mar 6.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Munich 81675, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsych.2009.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700302PMC
June 2009

Neuropsychological and positron emission tomography correlates in idiopathic environmental intolerances.

Scand J Work Environ Health 2007 Dec;33(6):447-53

Department of Psychiatry and Psychotherapy, Technical University (TU) of Munich, Klinikum rechts der Isar, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5271/sjweh.1164DOI Listing
December 2007

Cerebral metabolic correlates of the clinical dementia rating scale in mild cognitive impairment.

J Geriatr Psychiatry Neurol 2007 Jun;20(2):84-8

Department of Psychiatry, Medicine Technische Universität Munchen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0891988706297093DOI Listing
June 2007

Effects of cholinesterase inhibitors on behavioural disturbances in Alzheimer's disease: a systematic review.

Drugs Aging 2006 ;23(12):957-67

Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2165/00002512-200623120-00003DOI Listing
May 2007

Mapping scores onto stages: mini-mental state examination and clinical dementia rating.

Am J Geriatr Psychiatry 2006 Feb;14(2):139-44

Department of Psychiatry and Psychotherapy and the Institute of Medical Statistics and Epidemiology, Technische Universität München, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.JGP.0000192478.82189.a8DOI Listing
February 2006