Publications by authors named "Tim de Meyer"

88Publications

Chitin in strawberry cultivation: foliar growth and defense response promotion, but reduced fruit yield and disease resistance by nutrient imbalances.

Authors:
Caroline De Tender Bart Vandecasteele Bruno Verstraeten Sarah Ommeslag Tim De Meyer Jill De Visscher Peter Dawyndt Lieven Clement Tina Kyndt Jane Debode

Mol Plant Microbe Interact 2020 Nov 2. Epub 2020 Nov 2.

ILVO, 74875, Plant Science Unit, Merelbeke, Oost-Vlaanderen, Belgium;

View Article and Find Full Text PDF
November 2020

Molecular insights into the compatible and incompatible interactions between sugar beet and the beet cyst nematode.

Authors:
Razieh Ghaemi Ebrahim Pourjam Naser Safaie Bruno Verstraeten Seyed Bagher Mahmoudi Rahim Mehrabi Tim De Meyer Tina Kyndt

BMC Plant Biol 2020 Oct 22;20(1):483. Epub 2020 Oct 22.

Department of Biotechnology, Ghent University, Coupure Links 653, B-9000, Ghent, Belgium.

View Article and Find Full Text PDF
October 2020

Chorismate mutase and isochorismatase, two potential effectors of the migratory nematode Hirschmanniella oryzae, increase host susceptibility by manipulating secondary metabolite content of rice.

Authors:
Lander Bauters Tina Kyndt Tim De Meyer Kris Morreel Wout Boerjan Hannes Lefevere Godelieve Gheysen

Mol Plant Pathol 2020 Dec 20;21(12):1634-1646. Epub 2020 Oct 20.

Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
December 2020

Genome-wide DNA hypomethylation shapes nematode pattern-triggered immunity in plants.

Authors:
Mohammad Reza Atighi Bruno Verstraeten Tim De Meyer Tina Kyndt

New Phytol 2020 07 23;227(2):545-558. Epub 2020 Apr 23.

Department of Biotechnology, Ghent University, B-9000, Ghent, Belgium.

View Article and Find Full Text PDF
July 2020

Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals.

Authors:
Sam Kint Wim Trypsteen Ward De Spiegelaere Eva Malatinkova Sabine Kinloch-de Loes Tim De Meyer Wim Van Criekinge Linos Vandekerckhove

Clin Epigenetics 2020 02 28;12(1):36. Epub 2020 Feb 28.

HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital, Corneel Heymanslaan 10, Medical Research Building 2, 9000, Ghent, Belgium.

View Article and Find Full Text PDF
February 2020

Molecular correlates of hypothalamic development in songbird ontogeny in comparison with the telencephalon.

Authors:
Gaurav Majumdar Garima Yadav Julie Hamaide Louis Coussement Tim De Meyer Marleen Verhoye Wim Vanden Berghe Annemie Van Der Linden Jacques Balthazart

FASEB J 2020 04 13;34(4):4997-5015. Epub 2020 Feb 13.

Laboratory of Behavioral Neuroendocrinology, GIGA Neuroscience, University of Liege, Liege, Belgium.

View Article and Find Full Text PDF
April 2020

Muscle strength is a major determinant of the blood pressure response to isometric stress testing: the Asklepios population study.

Authors:
Caroline M Van Daele Julio A Chirinos Tim De Meyer Marc L De Buyzere Michel R Langlois Sofie Bekaert Patrick Segers Thierry C Gillebert Ernst R Rietzschel

J Hypertens 2020 02;38(2):224-234

Department of Cardiovascular Diseases, Ghent University and Ghent University Hospital, Ghent, Belgium.

View Article and Find Full Text PDF
February 2020

Selection of miRNA reference genes for plant defence studies in rice (Oryza sativa).

Authors:
Bruno Verstraeten Lien De Smet Tina Kyndt Tim De Meyer

Planta 2019 Dec 3;250(6):2101-2110. Epub 2019 Oct 3.

Department of Data Analysis and Mathematical Modelling, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
December 2019

MEXPRESS update 2019.

Authors:
Alexander Koch Jana Jeschke Wim Van Criekinge Manon van Engeland Tim De Meyer

Nucleic Acids Res 2019 07;47(W1):W561-W565

Department of Data Analysis and Mathematical Modelling, Ghent University, 9000 Ghent, Belgium.

View Article and Find Full Text PDF
July 2019

Targeted RNA-seq successfully identifies normal and pathogenic splicing events in breast/ovarian cancer susceptibility and Lynch syndrome genes.

Authors:
Rita D Brandão Klaas Mensaert Irene López-Perolio Demis Tserpelis Markos Xenakis Vanessa Lattimore Logan C Walker Anders Kvist Ana Vega Sara Gutiérrez-Enríquez Orland Díez Miguel de la Hoya Amanda B Spurdle Tim De Meyer Marinus J Blok

Int J Cancer 2019 07 7;145(2):401-414. Epub 2019 Feb 7.

Department of Clinical Genetics, Maastricht University Medical Centre+, GROW- School for Oncology and Developmental Biology, Maastricht, The Netherlands.

View Article and Find Full Text PDF
July 2019

Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies.

Authors:
Marij Gielen Geja J Hageman Evangelia E Antoniou Katarina Nordfjall Massimo Mangino Muthuswamy Balasubramanyam Tim de Meyer Audrey E Hendricks Erik J Giltay Steven C Hunt Jennifer A Nettleton Klelia D Salpea Vanessa A Diaz Ramin Farzaneh-Far Gil Atzmon Sarah E Harris Lifang Hou David Gilley Iiris Hovatta Jeremy D Kark Hisham Nassar David J Kurz Karen A Mather Peter Willeit Yun-Ling Zheng Sofia Pavanello Ellen W Demerath Line Rode Daniel Bunout Andrew Steptoe Lisa Boardman Amelia Marti Belinda Needham Wei Zheng Rosalind Ramsey-Goldman Andrew J Pellatt Jaakko Kaprio Jonathan N Hofmann Christian Gieger Giuseppe Paolisso Jacob B H Hjelmborg Lisa Mirabello Teresa Seeman Jason Wong Pim van der Harst Linda Broer Florian Kronenberg Barbara Kollerits Timo Strandberg Dan T A Eisenberg Catherine Duggan Josine E Verhoeven Roxanne Schaakxs Raffaela Zannolli Rosana M R Dos Reis Fadi J Charchar Maciej Tomaszewski Ute Mons Ilja Demuth Andrea Elena Iglesias Molli Guo Cheng Dmytro Krasnienkov Bianca D'Antono Marek Kasielski Barry J McDonnell Richard Paul Ebstein Kristina Sundquist Guillaume Pare Michael Chong Maurice P Zeegers

Am J Clin Nutr 2018 09;108(3):453-475

Departments of Complex Genetics.

View Article and Find Full Text PDF
September 2018

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

View Article and Find Full Text PDF
October 2018

A comprehensive overview of genomic imprinting in breast and its deregulation in cancer.

Authors:
Tine Goovaerts Sandra Steyaert Chari A Vandenbussche Jeroen Galle Olivier Thas Wim Van Criekinge Tim De Meyer

Nat Commun 2018 10 8;9(1):4120. Epub 2018 Oct 8.

Department Data Analysis and Mathematical Modelling, Ghent University, Coupure Links 653, 9000, Ghent, Belgium.

View Article and Find Full Text PDF
October 2018

Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure.

Authors:
Louis Coussement Selin Bolca Wim Van Criekinge Geert Trooskens Klaas Mensaert Katrien Poels Nathalie Roche Phillip Blondeel Lode Godderis Herman Depypere Tim De Meyer

Sci Rep 2018 09 11;8(1):13617. Epub 2018 Sep 11.

Department of Data Analysis and Mathematical Modelling, Faculty of Bioscience Engineering, Ghent University, Belgium, Coupure Links 653, B-9000, Ghent, Belgium.

View Article and Find Full Text PDF
September 2018

Telomere Length as Cardiovascular Aging Biomarker: JACC Review Topic of the Week.

Authors:
Tim De Meyer Tim Nawrot Sofie Bekaert Marc L De Buyzere Ernst R Rietzschel Vicente Andrés

J Am Coll Cardiol 2018 08;72(7):805-813

Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; CIBER de Enfermedades Cardiovasculares (CIBER-CV), Madrid, Spain.

View Article and Find Full Text PDF
August 2018

Author Correction: Analysis of DNA methylation in cancer: location revisited.

Authors:
Alexander Koch Sophie C Joosten Zheng Feng Tim C de Ruijter Muriel X Draht Veerle Melotte Kim M Smits Jurgen Veeck James G Herman Leander Van Neste Wim Van Criekinge Tim de Meyer Manon van Engeland

Nat Rev Clin Oncol 2018 07;15(7):467

Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands.

View Article and Find Full Text PDF
July 2018

Leukocyte telomere length and diet in the apparently healthy, middle-aged Asklepios population.

Authors:
Tim De Meyer Sofie Bekaert Marc L De Buyzere Dirk D De Bacquer Michel R Langlois Nitin Shivappa James R Hébert Thierry C Gillebert Ernst R Rietzschel Inge Huybrechts

Sci Rep 2018 04 25;8(1):6540. Epub 2018 Apr 25.

Department of Public Health, Ghent University, De Pintelaan 185, B-9000, Ghent, Belgium.

View Article and Find Full Text PDF
April 2018

Analysis of DNA methylation in cancer: location revisited.

Authors:
Alexander Koch Sophie C Joosten Zheng Feng Tim C de Ruijter Muriel X Draht Veerle Melotte Kim M Smits Jurgen Veeck James G Herman Leander Van Neste Wim Van Criekinge Tim De Meyer Manon van Engeland

Nat Rev Clin Oncol 2018 07;15(7):459-466

Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands.

View Article and Find Full Text PDF
July 2018

Letter by De Meyer Regarding Article, "Short Leukocyte Telomere Length Precedes Clinical Expression of Atherosclerosis: The Blood-and-Muscle Model".

Authors:
Tim De Meyer

Circ Res 2018 04;122(8):e71-e72

Department of Data Analysis and Mathematical Modelling, Ghent University, Belgium.

View Article and Find Full Text PDF
April 2018

( promoter hypermethylation and response to irinotecan in metastatic colorectal cancer.

Authors:
Linda J W Bosch Geert Trooskens Petur Snaebjornsson Veerle M H Coupé Sandra Mongera Josien C Haan Susan D Richman Miriam Koopman Jolien Tol Tim de Meyer Joost Louwagie Luc Dehaspe Nicole C T van Grieken Bauke Ylstra Henk M W Verheul Manon van Engeland Iris D Nagtegaal James G Herman Philip Quirke Matthew T Seymour Cornelis J A Punt Wim van Criekinge Beatriz Carvalho Gerrit A Meijer

Oncotarget 2017 Sep 27;8(38):63140-63154. Epub 2017 Jun 27.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

View Article and Find Full Text PDF
September 2017

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer.

Authors:
Tushar Tomar Nicolette G Alkema Leroy Schreuder Gert Jan Meersma Tim de Meyer Wim van Criekinge Harry G Klip Heidi Fiegl Els van Nieuwenhuysen Ignace Vergote Martin Widschwendter Ed Schuuring Ate G J van der Zee Steven de Jong G Bea A Wisman

BMC Med 2017 06 23;15(1):116. Epub 2017 Jun 23.

Department of Gynecologic Oncology, Cancer Research Center Groningen, University of Groningen, University Medical Center Groningen, PO Box 30001, 9700 RB, Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2017

Telomeres and Atherosclerosis: The Intricate Pursuit of Mechanistic Insight Through Epidemiology.

Authors:
Tim De Meyer Marc L De Buyzere

Hypertension 2017 08 19;70(2):243-244. Epub 2017 Jun 19.

From the Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Belgium; and Department of Cardiovascular Diseases, Ghent University Hospital, Belgium.

View Article and Find Full Text PDF
August 2017

Below-Ground Attack by the Root Knot Nematode Meloidogyne graminicola Predisposes Rice to Blast Disease.

Authors:
Tina Kyndt Henok Yimer Zemene Ashley Haeck Richard Singh David De Vleesschauwer Simon Denil Tim De Meyer Monica Höfte Kristof Demeestere Godelieve Gheysen

Mol Plant Microbe Interact 2017 03 29;30(3):255-266. Epub 2017 Mar 29.

1 Department Molecular Biotechnology, Ghent University, Coupure links 653, B-9000 Ghent, Belgium.

View Article and Find Full Text PDF
March 2017

Epigenetic sampling effects: nephrectomy modifies the clear cell renal cell cancer methylome.

Authors:
Christophe Van Neste Alexander Laird Fiach O'Mahony Wim Van Criekinge Dieter Deforce Filip Van Nieuwerburgh Thomas Powles David J Harrison Grant D Stewart Tim De Meyer

Cell Oncol (Dordr) 2017 Jun 10;40(3):293-297. Epub 2017 Jan 10.

Biobix: Laboratory of Bioinformatics and Computational Genomics, Department of Mathematical Modeling, Statistics and Bioninformatics, Ghent University, Coupure Links 653, 9000, Ghent, Belgium.

View Article and Find Full Text PDF
June 2017

A Four-Gene Promoter Methylation Marker Panel Consisting of and Predicts Survival of Clear Cell Renal Cell Cancer Patients.

Authors:
Iris J H van Vlodrop Sophie C Joosten Tim De Meyer Kim M Smits Leander Van Neste Veerle Melotte Marcella M L L Baldewijns Leo J Schouten Piet A van den Brandt Jana Jeschke Joo Mi Yi Kornel E Schuebel Nita Ahuja James G Herman Maureen J Aarts Fred T Bosman Wim Van Criekinge Manon van Engeland

Clin Cancer Res 2017 04 18;23(8):2006-2018. Epub 2016 Oct 18.

Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands.

View Article and Find Full Text PDF
April 2017

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma.

Authors:
Rong Wang Robert W van Leeuwen Aniek Boers Harry G Klip Tim de Meyer Renske D M Steenbergen Wim van Criekinge Ate G J van der Zee Ed Schuuring G Bea A Wisman

Oncotarget 2016 Dec;7(49):80735-80750

Department of Gynecologic Oncology, University of Groningen, University Medical Centre Groningen, Cancer Research Centre Groningen, Groningen, The Netherlands.

View Article and Find Full Text PDF
December 2016

Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients.

Authors:
Teofila Seremet Alexander Koch Yanina Jansen Max Schreuer Sofie Wilgenhof Véronique Del Marmol Danielle Liènard Kris Thielemans Kelly Schats Mark Kockx Wim Van Criekinge Pierre G Coulie Tim De Meyer Nicolas van Baren Bart Neyns

J Transl Med 2016 08 2;14(1):232. Epub 2016 Aug 2.

Department of Medical Oncology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium.

View Article and Find Full Text PDF
August 2016

Identification of long non-coding RNAs involved in neuronal development and intellectual disability.

Authors:
Eva D'haene Eva Z Jacobs Pieter-Jan Volders Tim De Meyer Björn Menten Sarah Vergult

Sci Rep 2016 06 20;6:28396. Epub 2016 Jun 20.

Center for Medical Genetics, Ghent University, Ghent University Hospital, Ghent, Belgium.

View Article and Find Full Text PDF
June 2016

Telomeres and Atherosclerosis: The Attrition of an Attractive Hypothesis.

Authors:
Ernst R Rietzschel Sofie Bekaert Tim De Meyer

J Am Coll Cardiol 2016 05;67(21):2477-9

Faculty of Bioscience Engineering, Department of Mathematical Modelling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
May 2016

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer.

Authors:
Grant D Stewart Thomas Powles Christophe Van Neste Alison Meynert Fiach O'Mahony Alexander Laird Dieter Deforce Filip Van Nieuwerburgh Geert Trooskens Wim Van Criekinge Tim De Meyer David J Harrison

Oncotarget 2016 May;7(18):25241-50

Scottish Collaboration On Translational Research into Renal Cell Cancer (SCOTRRCC), Scotland, UK.

View Article and Find Full Text PDF
May 2016

Corrigendum: A genome-wide search for epigenetically regulated genes in zebra finch using MethylCap-seq and RNA-seq.

Authors:
Sandra Steyaert Jolien Diddens Jeroen Galle Ellen De Meester Sarah De Keulenaer Antje Bakker Nina Sohnius-Wilhelmi Carolina Frankl-Vilches Annemie Van der Linden Wim Van Criekinge Wim Vanden Berghe Tim De Meyer

Sci Rep 2016 Mar 17;6:22472. Epub 2016 Mar 17.

View Article and Find Full Text PDF
March 2016

A genome-wide search for epigenetically [corrected] regulated genes in zebra finch using MethylCap-seq and RNA-seq.

Authors:
Sandra Steyaert Jolien Diddens Jeroen Galle Ellen De Meester Sarah De Keulenaer Antje Bakker Nina Sohnius-Wilhelmi Carolina Frankl-Vilches Annemie Van der Linden Wim Van Criekinge Wim Vanden Berghe Tim De Meyer

Sci Rep 2016 Feb 11;6:20957. Epub 2016 Feb 11.

Department of Mathematical Modelling, Statistics and Bioinformatics, University of Ghent, Ghent, Belgium.

View Article and Find Full Text PDF
February 2016

Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile.

Authors:
Tjinta Brinkhuizen Michel van Geel Simon L I J Denil Tim De Meyer Nicole W J Kelleners-Smeets Peter J F M Lohuis Frank J P Hoebers Véronique J L Winnepenninckx Maurice A M van Steensel Klara Mosterd

Exp Dermatol 2016 Apr 11;25(4):316-8. Epub 2016 Feb 11.

Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.

View Article and Find Full Text PDF
April 2016

Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison.

Authors:
Tim De Meyer Pierre Bady Geert Trooskens Sebastian Kurscheid Jocelyne Bloch Johan M Kros Johannes A Hainfellner Roger Stupp Mauro Delorenzi Monika E Hegi Wim Van Criekinge

Sci Rep 2015 Oct 20;5:15375. Epub 2015 Oct 20.

Dept. of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
October 2015

Is Southern blotting necessary to measure telomere length reproducibly? Authors' Response to: Commentary: The reliability of telomere length measurements.

Authors:
Carmen M Martin-Ruiz Duncan Baird Laureline Roger Petra Boukamp Damir Krunic Richard Cawthon Martin M Dokter Pim Van Der Harst Sofie Bekaert Tim De Meyer Goran Roos Ulrika Svenson Veryan Codd Nilesh J Samani Liane Mcglynn Paul G Shiels Karen A Pooley Alison M Dunning Rachel Cooper Andrew Wong Andrew Kingston Thomas Von Zglinicki

Int J Epidemiol 2015 Oct 24;44(5):1686-7. Epub 2015 Sep 24.

Institute for Ageing and Health, Newcastle University, Newcastle, UK,

View Article and Find Full Text PDF
October 2015

Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic.

Authors:
Carmen M Martin-Ruiz Duncan Baird Laureline Roger Petra Boukamp Damir Krunic Richard Cawthon Martin M Dokter Pim Van Der Harst Sofie Bekaert Tim De Meyer Goran Roos Ulrika Svenson Veryan Codd Nilesh J Samani Liane Mcglynn Paul G Shiels Karen A Pooley Alison M Dunning Rachel Cooper Andrew Wong Andrew Kingston Thomas Von Zglinicki

Int J Epidemiol 2015 Oct 24;44(5):1739-41. Epub 2015 Sep 24.

Institute for Ageing and Health, Newcastle University, Newcastle, UK,

View Article and Find Full Text PDF
October 2015

Reproducibility of Telomere Length Assessment--An International Collaborative Study.

Authors:
Carmen M Martin-Ruiz Duncan Baird Laureline Roger Petra Boukamp Damir Krunic Richard Cawthon Martin M Dokter Pim van der Harst Sofie Bekaert Tim de Meyer Goran Roos Ulrika Svenson Veryan Codd Nilesh J Samani Liane McGlynn Paul G Shiels Karen A Pooley Alison M Dunning Rachel Cooper Andrew Wong Andrew Kingston Thomas von Zglinicki

Int J Epidemiol 2015 Oct 24;44(5):1749-54. Epub 2015 Sep 24.

View Article and Find Full Text PDF
October 2015

Identification and validation of WISP1 as an epigenetic regulator of metastasis in oral squamous cell carcinoma.

Authors:
Martijn J A M Clausen Lieuwe J Melchers Mirjam F Mastik Lorian Slagter-Menkema Harry J M Groen Bernard F A M van der Laan Wim van Criekinge Tim de Meyer Simon Denil G Bea A Wisman Jan L N Roodenburg Ed Schuuring

Genes Chromosomes Cancer 2016 Jan 22;55(1):45-59. Epub 2015 Sep 22.

Department of Pathology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

View Article and Find Full Text PDF
January 2016

MEXPRESS: visualizing expression, DNA methylation and clinical TCGA data.

Authors:
Alexander Koch Tim De Meyer Jana Jeschke Wim Van Criekinge

BMC Genomics 2015 Aug 26;16:636. Epub 2015 Aug 26.

Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
August 2015

Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening.

Authors:
Brody Holohan Tim De Meyer Kimberly Batten Massimo Mangino Steven C Hunt Sofie Bekaert Marc L De Buyzere Ernst R Rietzschel Tim D Spector Woodring E Wright Jerry W Shay

Aging Cell 2015 Aug 7;14(4):669-77. Epub 2015 May 7.

Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.

View Article and Find Full Text PDF
August 2015

Mining for viral fragments in methylation enriched sequencing data.

Authors:
Klaas Mensaert Wim Van Criekinge Olivier Thas Ed Schuuring Renske D M Steenbergen G Bea A Wisman Tim De Meyer

Front Genet 2015 4;6:16. Epub 2015 Feb 4.

Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University Ghent, Belgium.

View Article and Find Full Text PDF
February 2015

PROTEOFORMER: deep proteome coverage through ribosome profiling and MS integration.

Authors:
Jeroen Crappé Elvis Ndah Alexander Koch Sandra Steyaert Daria Gawron Sarah De Keulenaer Ellen De Meester Tim De Meyer Wim Van Criekinge Petra Van Damme Gerben Menschaert

Nucleic Acids Res 2015 Mar 15;43(5):e29. Epub 2014 Dec 15.

Lab of Bioinformatics and Computational Genomics, Department of Mathematical Modeling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium

View Article and Find Full Text PDF
March 2015

On cross-sectional associations of leukocyte telomere length with cardiac systolic, diastolic and vascular function: the Asklepios study.

Authors:
Simon L I J Denil Ernst R Rietzschel Marc L De Buyzere Caroline M Van Daele Patrick Segers Dirk De Bacquer Wim Van Criekinge Sofie Bekaert Thierry C Gillebert Tim De Meyer

PLoS One 2014 15;9(12):e115071. Epub 2014 Dec 15.

Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
May 2016

ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation.

Authors:
Tom Sante Sarah Vergult Pieter-Jan Volders Wigard P Kloosterman Geert Trooskens Katleen De Preter Annelies Dheedene Frank Speleman Tim De Meyer Björn Menten

PLoS One 2014 12;9(12):e113800. Epub 2014 Dec 12.

Center for Medical Genetics, Faculty of Medicine and Health Sciences, Ghent University, Gent, Belgium.

View Article and Find Full Text PDF
October 2015

Reproducibility of telomere length assessment: an international collaborative study.

Authors:
Carmen M Martin-Ruiz Duncan Baird Laureline Roger Petra Boukamp Damir Krunic Richard Cawthon Martin M Dokter Pim van der Harst Sofie Bekaert Tim de Meyer Goran Roos Ulrika Svenson Veryan Codd Nilesh J Samani Liane McGlynn Paul G Shiels Karen A Pooley Alison M Dunning Rachel Cooper Andrew Wong Andrew Kingston Thomas von Zglinicki

Int J Epidemiol 2015 Oct 19;44(5):1673-83. Epub 2014 Sep 19.

Newcastle University Institute for Ageing, Newcastle University, Newcastle, UK,

View Article and Find Full Text PDF
October 2015

SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data.

Authors:
Sandra Steyaert Wim Van Criekinge Ayla De Paepe Simon Denil Klaas Mensaert Katrien Vandepitte Wim Vanden Berghe Geert Trooskens Tim De Meyer

Nucleic Acids Res 2014 Nov 18;42(20):e157. Epub 2014 Sep 18.

Department of Mathematical Modelling, Statistics and Bioinformatics, University of Ghent, Ghent 9000, Belgium.

View Article and Find Full Text PDF
November 2014

Systemic suppression of the shoot metabolism upon rice root nematode infection.

Authors:
Tina Kyndt Simon Denil Lander Bauters Wim Van Criekinge Tim De Meyer

PLoS One 2014 12;9(9):e106858. Epub 2014 Sep 12.

Department of Mathematical Modelling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
May 2015

Bacterial diversity assessment in Antarctic terrestrial and aquatic microbial mats: a comparison between bidirectional pyrosequencing and cultivation.

Authors:
Bjorn Tytgat Elie Verleyen Dagmar Obbels Karolien Peeters Aaike De Wever Sofie D'hondt Tim De Meyer Wim Van Criekinge Wim Vyverman Anne Willems

PLoS One 2014 2;9(6):e97564. Epub 2014 Jun 2.

Laboratory for Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
January 2015

Possible technical and biological explanations for the 'parental telomere length inheritance discrepancy' enigma.

Authors:
Tim De Meyer Dan T A Eisenberg

Eur J Hum Genet 2015 Jan 23;23(1):3-4. Epub 2014 Apr 23.

1] Department of Anthropology, University of Washington, Seattle, WA, USA [2] Center for Studies in Demography and Ecology, University of Washington, Seattle, WA, USA.

View Article and Find Full Text PDF
January 2015

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article and Find Full Text PDF
February 2014

Arterial stiffness and influences of the metabolic syndrome: a cross-countries study.

Authors:
Angelo Scuteri Pedro G Cunha E Agabiti Rosei Jolita Badariere Sofie Bekaert John R Cockcroft Jorge Cotter Francesco Cucca Marc L De Buyzere Tim De Meyer Luigi Ferrucci Osca Franco Nichola Gale Thierry C Gillebert A Hofman Michel Langlois Aleksandras Laucevicius Stephane Laurent Francesco U S Mattace Raso Cristopher H Morrell Maria Lorenza Muiesan Margaret M Munnery Rokas Navickas Pedro Oliveira Marco Orru' Maria Grazia Pilia Ernst R Rietzschel Ligita Ryliskyte Massimo Salvetti David Schlessinger Nuno Sousa Christodoulos Stefanadis James Strait Caroline Van Daele Isabel Villa Charalambos Vlachopoulos Jacqueline Witteman Panagiotis Xaplanteris Peter Nilsson Edward G Lakatta

Atherosclerosis 2014 Apr 30;233(2):654-660. Epub 2014 Jan 30.

Laboratory Cardiovascular Sciences, National Institute on Aging (NIA), NIH, Baltimore, USA.

View Article and Find Full Text PDF
April 2014

Rapid genetic adaptation precedes the spread of an exotic plant species.

Authors:
Katrien Vandepitte Tim de Meyer Kenny Helsen Kasper van Acker Isabel Roldán-Ruiz Joachim Mergeay Olivier Honnay

Mol Ecol 2014 May 21;23(9):2157-64. Epub 2014 Mar 21.

Plant Conservation and Population Biology, Biology Department, University of Leuven, Kasteelpark Arenberg 31, B-3001, Heverlee, Belgium.

View Article and Find Full Text PDF
May 2014

Gender and telomere length: systematic review and meta-analysis.

Authors:
Michael Gardner David Bann Laura Wiley Rachel Cooper Rebecca Hardy Dorothea Nitsch Carmen Martin-Ruiz Paul Shiels Avan Aihie Sayer Michelangela Barbieri Sofie Bekaert Claus Bischoff Angela Brooks-Wilson Wei Chen Cyrus Cooper Kaare Christensen Tim De Meyer Ian Deary Geoff Der Ana Diez Roux Annette Fitzpatrick Anjum Hajat Julius Halaschek-Wiener Sarah Harris Steven C Hunt Carol Jagger Hyo-Sung Jeon Robert Kaplan Masayuki Kimura Peter Lansdorp Changyong Li Toyoki Maeda Massimo Mangino Tim S Nawrot Peter Nilsson Katarina Nordfjall Giuseppe Paolisso Fu Ren Karl Riabowol Tony Robertson Goran Roos Jan A Staessen Tim Spector Nelson Tang Brad Unryn Pim van der Harst Jean Woo Chao Xing Mohammad E Yadegarfar Jae Yong Park Neal Young Diana Kuh Thomas von Zglinicki Yoav Ben-Shlomo

Exp Gerontol 2014 Mar 21;51:15-27. Epub 2013 Dec 21.

School of Social and Community Medicine, University of Bristol, Canynge Hall, Bristol, UK. Electronic address:

View Article and Find Full Text PDF
March 2014

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue: a preliminary study.

Authors:
Claudina A Pérez-Novo Yuan Zhang Simon Denil Geert Trooskens Tim De Meyer Wim Van Criekinge Paul Van Cauwenberge Luo Zhang Claus Bachert

Allergy Asthma Clin Immunol 2013 Dec 16;9(1):48. Epub 2013 Dec 16.

Upper Airways Research Laboratory, Department of Otorhinolaryngology, Ghent University Hospital, De Pintelaan 185, Ghent B-9000, Belgium.

View Article and Find Full Text PDF
December 2013

Next-generation technologies and data analytical approaches for epigenomics.

Authors:
Klaas Mensaert Simon Denil Geert Trooskens Wim Van Criekinge Olivier Thas Tim De Meyer

Environ Mol Mutagen 2014 Apr 10;55(3):155-70. Epub 2013 Dec 10.

Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
April 2014

A non-genetic, epigenetic-like mechanism of telomere length inheritance?

Authors:
Tim De Meyer Katrien Vandepitte Simon Denil Marc L De Buyzere Ernst R Rietzschel Sofie Bekaert

Eur J Hum Genet 2014 Jan 23;22(1):10-1. Epub 2013 Oct 23.

Bimetra, Clinical Research Center Ghent, Ghent University Hospital, Ghent, Belgium.

View Article and Find Full Text PDF
January 2014

The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer.

Authors:
Kevin Sharpe Grant D Stewart Alan Mackay Christophe Van Neste Charlotte Rofe Dan Berney Irfan Kayani Axel Bex Elaine Wan Fiach C O'Mahony Marie O'Donnell Simon Chowdhury Rukma Doshi Colan Ho-Yen Marco Gerlinger Dawn Baker Neil Smith Barry Davies Anju Sahdev Ekaterini Boleti Tim De Meyer Wim Van Criekinge Luis Beltran Yong-Jie Lu David J Harrison Andrew R Reynolds Tom Powles

Clin Cancer Res 2013 Dec 15;19(24):6924-34. Epub 2013 Oct 15.

Authors' Affiliations: Barts Cancer Institute, Queen Mary University of London; Experimental Cancer Medicine Centre, University College; The Institute of Cancer Research; Guys and St Thomas' Hospital; The Royal Free Hospital London, London; Edinburgh Urological Cancer Group, University of Edinburgh, Edinburgh; Astra Zeneca, Manchester; School of Medicine, University of St Andrews, Fife, United Kingdom; National Cancer Institute, Amsterdam, the Netherlands; and University of Ghent, Ghent, Belgium.

View Article and Find Full Text PDF
December 2013

Family history of cardiovascular disease and offspring echocardiographic left ventricular structure and function: the Asklepios Study.

Authors:
Caroline M Van daele Tim De Meyer Marc L De Buyzere Thierry C Gillebert Simon L I J Denil Sofie Bekaert Julio A Chirinos Guy G De Backer Dirk De Bacquer Ernst R Rietzschel

J Am Soc Echocardiogr 2013 Nov 28;26(11):1290-1297.e2. Epub 2013 Aug 28.

Department of Cardiovascular Diseases, Ghent University Hospital, Ghent, Belgium. Electronic address:

View Article and Find Full Text PDF
November 2013

Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones.

Authors:
Greet L Roef Ernst R Rietzschel Tim De Meyer Sofie Bekaert Marc L De Buyzere Caroline Van daele Kaatje Toye Jean-Marc Kaufman Youri E Taes

Clin Chim Acta 2013 Oct 24;425:227-32. Epub 2013 Aug 24.

Department of Endocrinology, Ghent University Hospital, Belgium. Electronic address:

View Article and Find Full Text PDF
October 2013

Transcriptional analysis through RNA sequencing of giant cells induced by Meloidogyne graminicola in rice roots.

Authors:
Hongli Ji Godelieve Gheysen Simon Denil Keith Lindsey Jennifer F Topping Kamrun Nahar Annelies Haegeman Winnok H De Vos Geert Trooskens Wim Van Criekinge Tim De Meyer Tina Kyndt

J Exp Bot 2013 Sep 23;64(12):3885-98. Epub 2013 Jul 23.

Department of Molecular Biotechnology, Ghent University, Coupure Links 653, B-9000, Ghent, Belgium.

View Article and Find Full Text PDF
September 2013

The CpG island methylator phenotype: what's in a name?

Authors:
Laura A E Hughes Veerle Melotte Joachim de Schrijver Michiel de Maat Vincent T H B M Smit Judith V M G Bovée Pim J French Piet A van den Brandt Leo J Schouten Tim de Meyer Wim van Criekinge Nita Ahuja James G Herman Matty P Weijenberg Manon van Engeland

Cancer Res 2013 Oct 25;73(19):5858-68. Epub 2013 Jun 25.

Authors' Affiliations: Departments of Epidemiology and Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht; Department of Surgery, Orbis Medical Center, Sittard-Geleen; Department of Pathology, Leiden University Medical Center, Leiden; Department of Neurology, Erasmus University Medical Center, Erasmus University, Rotterdam, the Netherlands; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium; and The Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article and Find Full Text PDF
October 2013

Addition of a novel, protective family history category allows better profiling of cardiovascular risk and atherosclerotic burden in the general population. The Asklepios Study.

Authors:
Caroline M Van daele Tim De Meyer Marc L De Buyzere Thierry C Gillebert Simon L I J Denil Sofie Bekaert Julio A Chirinos Patrick Segers Guy G De Backer Dirk De Bacquer Ernst R Rietzschel

PLoS One 2013 2;8(5):e63185. Epub 2013 May 2.

Department of Cardiovascular Diseases, Ghent University Hospital, Ghent, Belgium.

View Article and Find Full Text PDF
December 2013

Coronary spasm after the topical use of cocaine in nasal surgery.

Authors:
Guy D Lenders Philippe G Jorens Tim De Meyer Tom Vandendriessche Walter Verbrugghe Christiaan J Vrints

Am J Case Rep 2013 18;14:76-9. Epub 2013 Mar 18.

Department of Cardiology, University Hospital Antwerp, Edegem, Belgium.

View Article and Find Full Text PDF
April 2013

Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing.

Authors:
Tim De Meyer Evi Mampaey Michaël Vlemmix Simon Denil Geert Trooskens Jean-Pierre Renard Sarah De Keulenaer Pierre Dehan Gerben Menschaert Wim Van Criekinge

PLoS One 2013 15;8(3):e59068. Epub 2013 Mar 15.

Department of Mathematical Modelling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
October 2013

The impact of extensive clonal growth on fine-scale mating patterns: a full paternity analysis of a lily-of-the-valley population (Convallaria majalis).

Authors:
Katrien Vandepitte Tim De Meyer Hans Jacquemyn Isabel Roldán-Ruiz Olivier Honnay

Ann Bot 2013 Apr 24;111(4):623-8. Epub 2013 Feb 24.

Plant Conservation and Population Biology, Biology Department, University of Leuven, Kasteelpark Arenberg 31, Heverlee, Belgium.

View Article and Find Full Text PDF
April 2013

Associations of rs4704397 in phosphodiesterase 8B with thyrotropin and thyroid hormone concentrations.

Authors:
Greet L Roef Ernst R Rietzschel Tim De Meyer Sofie Bekaert Marc L De Buyzere Jean-Marc Kaufman Youri E Taes

Thyroid 2013 Mar;23(3):376-7

View Article and Find Full Text PDF
March 2013

No shorter telomeres in subjects with a family history of cardiovascular disease in the Asklepios study.

Authors:
Tim De Meyer Caroline M Van Daele Marc L De Buyzere Simon Denil Dirk De Bacquer Patrick Segers Luc Cooman Guy G De Backer Thierry C Gillebert Sofie Bekaert Ernst R Rietzschel

Arterioscler Thromb Vasc Biol 2012 Dec 18;32(12):3076-81. Epub 2012 Oct 18.

Department of Mathematical Modelling, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
December 2012

Transcriptional reprogramming by root knot and migratory nematode infection in rice.

Authors:
Tina Kyndt Simon Denil Annelies Haegeman Geert Trooskens Lander Bauters Wim Van Criekinge Tim De Meyer Godelieve Gheysen

New Phytol 2012 Nov 17;196(3):887-900. Epub 2012 Sep 17.

Department of Molecular Biotechnology, Ghent University (UGent), Ghent, Belgium.

View Article and Find Full Text PDF
November 2012

Transcriptome analysis of rice mature root tissue and root tips in early development by massive parallel sequencing.

Authors:
Tina Kyndt Simon Denil Annelies Haegeman Geert Trooskens Tim De Meyer Wim Van Criekinge Godelieve Gheysen

J Exp Bot 2012 Mar 2;63(5):2141-57. Epub 2012 Jan 2.

Department of Molecular Biotechnology, Ghent University, Coupure Links 653, Ghent, Belgium.

View Article and Find Full Text PDF
March 2012

Screening of soy and milk protein hydrolysates for their ability to activate the CCK1 receptor.

Authors:
Dorien Staljanssens John Van Camp Annelies Billiet Tim De Meyer Nadin Al Shukor Winnok H De Vos Guy Smagghe

Peptides 2012 Mar 26;34(1):226-31. Epub 2011 Nov 26.

Department of Crop Protection, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
March 2012

Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.

Authors:
Gary F Mitchell Germaine C Verwoert Kirill V Tarasov Aaron Isaacs Albert V Smith Yasmin Ernst R Rietzschel Toshiko Tanaka Yongmei Liu Afshin Parsa Samer S Najjar Kevin M O'Shaughnessy Sigurdur Sigurdsson Marc L De Buyzere Martin G Larson Mark P S Sie Jeanette S Andrews Wendy S Post Francesco U S Mattace-Raso Carmel M McEniery Gudny Eiriksdottir Patrick Segers Ramachandran S Vasan Marie Josee E van Rijn Timothy D Howard Patrick F McArdle Abbas Dehghan Elizabeth S Jewell Stephen J Newhouse Sofie Bekaert Naomi M Hamburg Anne B Newman Albert Hofman Angelo Scuteri Dirk De Bacquer Mohammad Arfan Ikram Bruce M Psaty Christian Fuchsberger Matthias Olden Louise V Wain Paul Elliott Nicholas L Smith Janine F Felix Jeanette Erdmann Joseph A Vita Kim Sutton-Tyrrell Eric J G Sijbrands Serena Sanna Lenore J Launer Tim De Meyer Andrew D Johnson Anna F C Schut David M Herrington Fernando Rivadeneira Manuela Uda Ian B Wilkinson Thor Aspelund Thierry C Gillebert Luc Van Bortel Emelia J Benjamin Ben A Oostra Jingzhong Ding Quince Gibson André G Uitterlinden Gonçalo R Abecasis John R Cockcroft Vilmundur Gudnason Guy G De Backer Luigi Ferrucci Tamara B Harris Alan R Shuldiner Cornelia M van Duijn Daniel Levy Edward G Lakatta Jacqueline C M Witteman

Circ Cardiovasc Genet 2012 Feb 8;5(1):81-90. Epub 2011 Nov 8.

Cardiovascular Engineering Inc., 1 Edgewater Drive, Norwood, MA 02062, USA.

View Article and Find Full Text PDF
February 2012

Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells.

Authors:
Khalil Abou-El-Ardat Pieter Monsieurs Nataša Anastasov Mike Atkinson Hanane Derradji Tim De Meyer Sofie Bekaert Wim Van Criekinge Sarah Baatout

Mutat Res 2012 Mar 20;731(1-2):27-40. Epub 2011 Oct 20.

Centre d'Etude de l'Energie Nucléaire, Boeretang, Belgium.

View Article and Find Full Text PDF
March 2012

Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system.

Authors:
Khalil Abou-El-Ardat Hanane Derradji Winnok de Vos Tim de Meyer Sofie Bekaert Wim van Criekinge Sarah Baatout

Int J Oncol 2011 Dec 29;39(6):1429-41. Epub 2011 Aug 29.

Laboratory of Molecular and Cellular Biology, Radiobiology Unit, Belgian Nuclear Research Center (SCK-CEN), 2400 Mol, Belgium.

View Article and Find Full Text PDF
December 2011

Telomere length integrates psychological factors in the successful aging story, but what about the biology?

Authors:
Tim De Meyer

Psychosom Med 2011 Sep 26;73(7):524-7. Epub 2011 Aug 26.

View Article and Find Full Text PDF
September 2011

Telomere length and cardiovascular aging: the means to the ends?

Authors:
Tim De Meyer Ernst R Rietzschel Marc L De Buyzere Wim Van Criekinge Sofie Bekaert

Ageing Res Rev 2011 Apr 23;10(2):297-303. Epub 2010 Nov 23.

Dept. of Molecular Biotechnology, FBE, Ghent University, Belgium.

View Article and Find Full Text PDF
April 2011

Evaluation of standard and advanced preprocessing methods for the univariate analysis of blood serum 1H-NMR spectra.

Authors:
Tim De Meyer Davy Sinnaeve Bjorn Van Gasse Ernst-R Rietzschel Marc L De Buyzere Michel R Langlois Sofie Bekaert José C Martins Wim Van Criekinge

Anal Bioanal Chem 2010 Oct 17;398(4):1781-90. Epub 2010 Aug 17.

Laboratory for Bioinformatics and Computational Genomics, Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.

View Article and Find Full Text PDF
October 2010

A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study.

Authors:
Ian Buysschaert Kathryn F Carruthers Donald R Dunbar Gilian Peuteman Ernst Rietzschel Ann Belmans Ann Hedley Tim De Meyer Andrzej Budaj Frans Van de Werf Diether Lambrechts Keith A A Fox

Eur Heart J 2010 May 15;31(9):1132-41. Epub 2010 Mar 15.

Vesalius Research Center, VIB and KULeuven, Campus Gasthuisberg, Herestraat 49, Box 912, B-3000 Leuven, Belgium.

View Article and Find Full Text PDF
May 2010

High content analysis of human fibroblast cell cultures after exposure to space radiation.

Authors:
Birger Dieriks Winnok De Vos Geert Meesen Kaat Van Oostveldt Tim De Meyer Myriam Ghardi Sarah Baatout Patrick Van Oostveldt

Radiat Res 2009 Oct;172(4):423-36

Laboratory for Bio-Imaging and Molecular Cytology, Department of Molecular Biotechnology, Ghent University, 9000 Gent, Belgium.

View Article and Find Full Text PDF
October 2009

Systemic telomere length and preclinical atherosclerosis: the Asklepios Study.

Authors:
Tim De Meyer Ernst R Rietzschel Marc L De Buyzere Michel R Langlois Dirk De Bacquer Patrick Segers Piet Van Damme Guy G De Backer Patrick Van Oostveldt Wim Van Criekinge Thierry C Gillebert Sofie Bekaert

Eur Heart J 2009 Dec;30(24):3074-81

Department of Molecular Biotechnology, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.

View Article and Find Full Text PDF
December 2009

Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.

Authors:
Hanane Derradji Sofie Bekaert Tim De Meyer Paul Jacquet Khalil Abou-El-Ardat Myriam Ghardi Michaux Arlette Sarah Baatout

Dev Biol 2008 Oct 7;322(2):302-13. Epub 2008 Aug 7.

Laboratory for Molecular and Cellular Biology Belgian Nuclear Research Centre, SCKCEN, Mol, Belgium.

View Article and Find Full Text PDF
October 2008

Lower red blood cell counts in middle-aged subjects with shorter peripheral blood leukocyte telomere length.

Authors:
Tim De Meyer Marc L De Buyzere Michel Langlois Ernst R Rietzschel Peter Cassiman Dirk De Bacquer Patrick Van Oostveldt Guy G De Backer Thierry C Gillebert Wim Van Criekinge Sofie Bekaert

Aging Cell 2008 Oct 28;7(5):700-5. Epub 2008 Jul 28.

Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Ghent, Belgium.

View Article and Find Full Text PDF
October 2008

NMR-based characterization of metabolic alterations in hypertension using an adaptive, intelligent binning algorithm.

Authors:
Tim De Meyer Davy Sinnaeve Bjorn Van Gasse Elena Tsiporkova Ernst R Rietzschel Marc L De Buyzere Thierry C Gillebert Sofie Bekaert José C Martins Wim Van Criekinge

Anal Chem 2008 May 18;80(10):3783-90. Epub 2008 Apr 18.

Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.

View Article and Find Full Text PDF
May 2008

Studying telomeres in a longitudinal population based study.

Authors:
Tim De Meyer Ernst R Rietzschel Marc L De Buyzere Wim Van Criekinge Sofie Bekaert

Front Biosci 2008 Jan 1;13:2960-70. Epub 2008 Jan 1.

Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article and Find Full Text PDF
January 2008

PubMeth: a cancer methylation database combining text-mining and expert annotation.

Authors:
Maté Ongenaert Leander Van Neste Tim De Meyer Gerben Menschaert Sofie Bekaert Wim Van Criekinge

Nucleic Acids Res 2008 Jan 11;36(Database issue):D842-6. Epub 2007 Oct 11.

Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Laboratory for Bioinformatics and Computational Genomics, Ghent University, B-9000 Ghent, Belgium.

View Article and Find Full Text PDF
January 2008

Paternal age at birth is an important determinant of offspring telomere length.

Authors:
Tim De Meyer Ernst R Rietzschel Marc L De Buyzere Dirk De Bacquer Wim Van Criekinge Guy G De Backer Thierry C Gillebert Patrick Van Oostveldt Sofie Bekaert

Hum Mol Genet 2007 Dec 19;16(24):3097-102. Epub 2007 Sep 19.

Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.

View Article and Find Full Text PDF
December 2007

Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease.

Authors:
Sofie Bekaert Tim De Meyer Ernst R Rietzschel Marc L De Buyzere Dirk De Bacquer Michel Langlois Patrick Segers Luc Cooman Piet Van Damme Peter Cassiman Wim Van Criekinge Pascal Verdonck Guy G De Backer Thierry C Gillebert Patrick Van Oostveldt

Aging Cell 2007 Oct;6(5):639-47

Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.

View Article and Find Full Text PDF
October 2007

Telomere attrition as ageing biomarker.

Authors:
Sofie Bekaert Tim De Meyer Patrick Van Oostveldt

Anticancer Res 2005 Jul-Aug;25(4):3011-21

Department of Molecular Biotechnology, Faculty for Bioscience Engineering, Ghent University, Belgium.

View Article and Find Full Text PDF
September 2005

Telomere shortening is associated with malformation in p53-deficient mice after irradiation during specific stages of development.

Authors:
Sofie Bekaert Hanane Derradji Tim De Meyer Arlette Michaux Jasmine Buset Mieke Neefs Max Mergeay Paul Jacquet Patrick Van Oostveldt Sarah Baatout

DNA Repair (Amst) 2005 Aug;4(9):1028-37

Laboratory for Biochemistry and Molecular Cytology, Department for Molecular Biotechnology, Faculty of Bioscience Engineering FBE, Ghent University, Belgium.

View Article and Find Full Text PDF
August 2005