Publications by authors named "Tim Thomas"

82Publications

DOT1L in prostate cancer.

Authors:
Tim Thomas

Nat Rev Urol 2020 Sep 7. Epub 2020 Sep 7.

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0374-0DOI Listing
September 2020

cfDNA methylation analysis detects RCC.

Authors:
Tim Thomas

Nat Rev Urol 2020 Aug 11. Epub 2020 Aug 11.

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0366-0DOI Listing
August 2020

TVT-O for SUI.

Authors:
Tim Thomas

Nat Rev Urol 2020 Jul;17(7):370

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0342-8DOI Listing
July 2020

Deep learning in MIBC.

Authors:
Tim Thomas

Nat Rev Urol 2020 Aug;17(8):432

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0344-6DOI Listing
August 2020

Comparing outcomes of SMP and Miniperc.

Authors:
Tim Thomas

Nat Rev Urol 2020 Jul;17(7):370

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0329-5DOI Listing
July 2020

Novel PDL1 regulation mechanism provides opportunity for prostate cancer treatment.

Authors:
Tim Thomas

Nat Rev Urol 2020 May;17(5):256

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0323-yDOI Listing
May 2020

Oral ADT demonstrates greater efficacy than existing injectable treatment.

Authors:
Tim Thomas

Nat Rev Urol 2020 May;17(5):256

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0322-zDOI Listing
May 2020

SABR improves outcomes in men with recurrent oligometastatic prostate cancer.

Authors:
Tim Thomas

Nat Rev Urol 2020 May;17(5):256

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0321-0DOI Listing
May 2020

Chromatin-Binding Protein PHF6 Regulates Activity-Dependent Transcriptional Networks to Promote Hunger Response.

Cell Rep 2020 Mar;30(11):3717-3728.e6

Collaborative Innovation Center for Brain Science, Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai 201210, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.02.085DOI Listing
March 2020

Action plan for hit identification (APHID): KAT6A as a case study.

Future Med Chem 2020 Mar 17;12(5):423-437. Epub 2020 Feb 17.

School of Pharmaceutical Sciences, Nanjing Tech University, Number 30 South Puzhu Road, Nanjing, 211816, PR China.

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http://dx.doi.org/10.4155/fmc-2019-0212DOI Listing
March 2020

Automated systems comparable to expert pathologists for prostate cancer Gleason grading.

Authors:
Tim Thomas

Nat Rev Urol 2020 03;17(3):131

Nature Reviews Urology, .

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http://dx.doi.org/10.1038/s41585-020-0294-zDOI Listing
March 2020

MOZ directs the distal-less homeobox gene expression program during craniofacial development.

Development 2019 07 24;146(14). Epub 2019 Jul 24.

Walter and Eliza Hall Institute of Medical Research, Melbourne, Parkville, VIC 3052, Australia

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http://dx.doi.org/10.1242/dev.175042DOI Listing
July 2019

Are transplantable stem cells required for adult hematopoiesis?

Exp Hematol 2019 07 5;75:1-10. Epub 2019 Jun 5.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X193032
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http://dx.doi.org/10.1016/j.exphem.2019.05.007DOI Listing
July 2019

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.

Cell Rep 2019 04;27(2):442-454.e5

Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.03.048DOI Listing
April 2019

KAT8 selectively inhibits antiviral immunity by acetylating IRF3.

J Exp Med 2019 04 6;216(4):772-785. Epub 2019 Mar 6.

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China

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http://www.jem.org/lookup/doi/10.1084/jem.20181773
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http://dx.doi.org/10.1084/jem.20181773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446880PMC
April 2019

Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective -deficient mice.

RNA 2018 12 25;24(12):1856-1870. Epub 2018 Sep 25.

Development and Cancer Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1261/rna.068221.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239176PMC
December 2018

Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals.

Bioessays 2018 10 24;40(10):e1800078. Epub 2018 Aug 24.

Department of Medical Biology, The University of Melbourne, 1G Royal Parade, Parkville, Melbourne, Victoria, 3052, Australia.

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http://dx.doi.org/10.1002/bies.201800078DOI Listing
October 2018

MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.

Exp Hematol 2017 03 24;47:83-97.e8. Epub 2016 Oct 24.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.10.006DOI Listing
March 2017

Essential role for the histone acetyltransferase KAT7 in T cell development, fitness, and survival.

J Leukoc Biol 2017 04 12;101(4):887-892. Epub 2016 Oct 12.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; and

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http://dx.doi.org/10.1189/jlb.1MA0816-338RDOI Listing
April 2017

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells.

Blood 2016 11 23;128(19):2307-2318. Epub 2016 Sep 23.

The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1182/blood-2015-10-676072DOI Listing
November 2016

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Cell Rep 2016 09;16(12):3311-3321

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.08.056DOI Listing
September 2016

The First New Zealanders? An Alternative Interpretation of Stable Isotope Data from Wairau Bar, New Zealand.

PLoS One 2015 28;10(10):e0135214. Epub 2015 Oct 28.

Department of Anthropology and Archaeology, University of Otago, Dunedin, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135214PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624984PMC
January 2016

Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome.

Genom Data 2014 Dec 2;2:314-7. Epub 2014 Oct 2.

Walter and Eliza Hall Institute of Medical Research, Victoria, Australia ; Centre for Cancer Biology, University of South Australia, Department of Molecular Pathology, SA Pathology, Adelaide, Australia ; School of Molecular and Biomedical Bioscience, University of Adelaide, Adelaide, Australia ; School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.1016/j.gdata.2014.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535870PMC
December 2014

Response to Heard et al.

EMBO J 2015 Oct;34(19):2396-7

The Walter and Eliza Hall Institute, Parkville, Vic., Australia Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia.

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http://dx.doi.org/10.15252/embj.201592761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601660PMC
October 2015

MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo.

Proc Natl Acad Sci U S A 2015 Apr 14;112(17):5437-42. Epub 2015 Apr 14.

Development and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia;

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http://dx.doi.org/10.1073/pnas.1422872112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418851PMC
April 2015

Mesodermal expression of Moz is necessary for cardiac septum development.

Dev Biol 2015 Jul 23;403(1):22-9. Epub 2015 Apr 23.

Walter and Eliza Hall Institute of Medical Research, Melbourne 3052, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Melbourne 3052, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2015.04.011DOI Listing
July 2015

Excessive versus physiologically relevant levels of retinoic acid in embryonic stem cell differentiation.

Stem Cells 2014 Jun;32(6):1451-8

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/stem.1604DOI Listing
June 2014

Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ.

Proc Natl Acad Sci U S A 2014 Jul 16;111(26):9585-90. Epub 2014 Jun 16.

Divisions of Immunology,Departments of Medical Biology and

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http://dx.doi.org/10.1073/pnas.1402485111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084455PMC
July 2014

E-O technique is superior to E-C technique in manikins during single person bag mask ventilation performed by novices.

J Clin Monit Comput 2014 Jun 8;28(3):269-73. Epub 2013 Nov 8.

Department of Anaesthesia, Kasturba Hospital, Kasturba Medical College, Manipal University, Manipal, 576104, India,

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http://link.springer.com/content/pdf/10.1007/s10877-013-9531
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http://link.springer.com/10.1007/s10877-013-9531-9
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http://dx.doi.org/10.1007/s10877-013-9531-9DOI Listing
June 2014

Umesh's intubation detector (UID) for rapid and reliable identification of tracheal intubation by novices in anaesthetised, paralysed adult patients.

J Clin Monit Comput 2013 Oct 20;27(5):517-20. Epub 2013 Mar 20.

Department of Anaesthesia, Kasturba Medical College, Kasturba Hospital, Manipal University, Manipal, 576104, India,

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http://dx.doi.org/10.1007/s10877-013-9455-4DOI Listing
October 2013

Validation of the new intubation detector device: a manikin study.

J Clin Monit Comput 2012 Dec 13;26(6):423-7. Epub 2012 May 13.

Department of Anaesthesiology, Kasturba Medical College, Manipal University, Manipal 576 104, India.

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http://dx.doi.org/10.1007/s10877-012-9369-6DOI Listing
December 2012

Migration of sympathetic preganglionic neurons in the spinal cord of a C3G-deficient mouse suggests that C3G acts in the reelin signaling pathway.

J Comp Neurol 2012 Oct;520(14):3194-202

Department of Neurobiology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://doi.wiley.com/10.1002/cne.23086
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http://dx.doi.org/10.1002/cne.23086DOI Listing
October 2012

Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells.

J Cell Sci 2012 Jan 13;125(Pt 2):295-309. Epub 2012 Feb 13.

The Walter and Eliza Hall Institute of Medical Research, Parkville 3050, Victoria, Australia.

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http://dx.doi.org/10.1242/jcs.077271DOI Listing
January 2012

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia.

J Cell Biol 2012 Jan 2;196(1):29-36. Epub 2012 Jan 2.

Brain Development and Regeneration Laboratory, Florey Neuroscience Institutes, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1083/jcb.201105009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255971PMC
January 2012

Chromatin immunoprecipitation of mouse embryos.

Methods Mol Biol 2012 ;809:335-52

The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-61779-376-9_23DOI Listing
March 2012

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

Mol Cell Biol 2011 Feb 13;31(4):845-60. Epub 2010 Dec 13.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00159-10
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http://dx.doi.org/10.1128/MCB.00159-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028655PMC
February 2011

Bringing comfort to Haiti.

Plast Surg Nurs 2010 Jul-Sep;30(3):133-49; quiz 150-1

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http://dx.doi.org/10.1097/PSN.0b013e3181ee16ceDOI Listing
January 2011

Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity.

Dev Cell 2009 Nov;17(5):674-86

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S153458070900428
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http://dx.doi.org/10.1016/j.devcel.2009.10.006DOI Listing
November 2009

MYST family histone acetyltransferases take center stage in stem cells and development.

Bioessays 2009 Oct;31(10):1050-61

Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

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http://dx.doi.org/10.1002/bies.200900051DOI Listing
October 2009

Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.

Mol Cell Biol 2008 Aug 9;28(16):5093-105. Epub 2008 Jun 9.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1128/MCB.02202-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519697PMC
August 2008

Protein and gene expression analysis of Phf6, the gene mutated in the Börjeson-Forssman-Lehmann Syndrome of intellectual disability and obesity.

Gene Expr Patterns 2007 Oct 6;7(8):858-71. Epub 2007 Jul 6.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic. 3050, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S1567133X0700071
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http://dx.doi.org/10.1016/j.modgep.2007.06.007DOI Listing
October 2007

The genes coding for the MYST family histone acetyltransferases, Tip60 and Mof, are expressed at high levels during sperm development.

Gene Expr Patterns 2007 Jun 31;7(6):657-65. Epub 2007 Mar 31.

The Walter and Eliza Hall Institute of Medical Research Parkville, Victoria, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S1567133X0700042
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http://dx.doi.org/10.1016/j.modgep.2007.03.005DOI Listing
June 2007

The diverse biological roles of MYST histone acetyltransferase family proteins.

Cell Cycle 2007 Mar 15;6(6):696-704. Epub 2007 Mar 15.

The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia.

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http://dx.doi.org/10.4161/cc.6.6.4013DOI Listing
March 2007

The transcriptional coactivator Querkopf controls adult neurogenesis.

J Neurosci 2006 Nov;26(44):11359-70

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1523/JNEUROSCI.2247-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674553PMC
November 2006

C3G regulates the size of the cerebral cortex neural precursor population.

EMBO J 2006 Aug 20;25(15):3652-63. Epub 2006 Jul 20.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/sj.emboj.7601234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538562PMC
August 2006

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

Dev Biol 2006 May 20;293(1):90-103. Epub 2006 Mar 20.

Monash Immunology and Stem Cell Laboratories, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.ydbio.2006.01.023DOI Listing
May 2006

Development of hydrocephalus in mice lacking SOCS7.

Proc Natl Acad Sci U S A 2004 Oct 19;101(43):15446-51. Epub 2004 Oct 19.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1073/pnas.0406870101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC524464PMC
October 2004

Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.

Cell Physiol Biochem 2004 ;14(4-6):351-60

Cell Physiology Group, Medical Faculty, Martin-Luther-University Halle, Germany.

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http://dx.doi.org/10.1159/000080345DOI Listing
February 2005

Querkopf, a histone acetyltransferase, is essential for embryonic neurogenesis.

Front Biosci 2004 Jan 1;9:24-31. Epub 2004 Jan 1.

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.2741/1208DOI Listing
January 2004

Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3.

Nat Med 2003 Dec 9;9(12):1513-9. Epub 2003 Nov 9.

Rotary Bone Marrow Research Laboratories, c/o Royal Melbourne Hospital Post Office, Grattan Street, Parkville, Victoria, Australia 3050.

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http://www.nature.com/articles/nm961
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http://dx.doi.org/10.1038/nm961DOI Listing
December 2003

Assessing the impact of major oil spills on seabird populations.

Mar Pollut Bull 2003 Jul;46(7):900-2

University of Aberdeen (SOTEAG), c/o East House, Sumburgh Head Lighthouse, ZE3 9JN Scotland, Virkie, Shetland, UK.

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http://dx.doi.org/10.1016/S0025-326X(03)00098-5DOI Listing
July 2003

The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation.

Development 2003 Jan;130(2):355-67

Development and Neurobiology, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1242/dev.00217DOI Listing
January 2003

Gcm1 expression defines three stages of chorio-allantoic interaction during placental development.

Mech Dev 2002 Jul;115(1-2):27-34

Department of Molecular, Cellular and Developmental Biology, Box 1126, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/s0925-4773(02)00095-3DOI Listing
July 2002