Tim Maughan

Tim Maughan

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Tim Maughan

Tim Maughan

Publications by authors named "Tim Maughan"

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Guidelines for using sigQC for systematic evaluation of gene signatures.

Nat Protoc 2019 05 10;14(5):1377-1400. Epub 2019 Apr 10.

Computational Biology and Integrative Genomics Lab, MRC/CRUK Oxford Institute and Department of Oncology, University of Oxford, Oxford, UK.

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http://www.nature.com/articles/s41596-019-0136-8
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http://dx.doi.org/10.1038/s41596-019-0136-8DOI Listing
May 2019

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Nat Commun 2019 05 14;10(1):2154. Epub 2019 May 14.

Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://www.nature.com/articles/s41467-019-09775-w
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http://dx.doi.org/10.1038/s41467-019-09775-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517433PMC
May 2019

Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses.

Oncotarget 2019 May 21;10(36):3408-3423. Epub 2019 May 21.

Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.26909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534362PMC
May 2019

[F]Fluoromisonidazole PET in rectal cancer.

EJNMMI Res 2017 Sep 20;7(1):78. Epub 2017 Sep 20.

CRUK/MRC Oxford Institute of Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Off Roosevelt Drive, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1186/s13550-017-0324-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607050PMC
September 2017

Standardising RNA profiling based biomarker application in cancer-The need for robust control of technical variables.

Biochim Biophys Acta Rev Cancer 2017 Aug 23;1868(1):258-272. Epub 2017 May 23.

Centre for Cancer Research and Cell Biology, Queen's University Belfast, UK; Northern Ireland Molecular Pathology Laboratory, Queen's University Belfast, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2017.05.005DOI Listing
August 2017

Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study.

Anticancer Drugs 2017 06;28(5):546-550

aDepartment of Oncology, University College London Hospital bCancer Research UK & UCL Cancer Trials Centre cMRC Clinical Trials Unit at UCL dUCL Cancer Institute, London, UK eInstitute of Cancer & Genetics, Cardiff University School of Medicine, Velindre Hospital, Cardiff fCRUK/MRC Oxford Institute for Radiation, Oxford, UK gOncology Institute, Shaare Zedek Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1097/CAD.0000000000000488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390854PMC
June 2017

From Rosalind Franklin to Barack Obama: Data Sharing Challenges and Solutions in Genomics and Personalised Medicine.

New Bioeth 2017 Apr;23(1):64-73

c CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford , Oxford , UK.

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http://dx.doi.org/10.1080/20502877.2017.1314883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448399PMC
April 2017

The Promise and the Hype of 'Personalised Medicine'.

Authors:
Tim Maughan

New Bioeth 2017 Apr;23(1):13-20

a CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford , Oxford , UK.

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http://dx.doi.org/10.1080/20502877.2017.1314886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448398PMC
April 2017

Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer.

Radiother Oncol 2016 11 10;121(2):232-238. Epub 2016 Nov 10.

Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, The University of Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2016.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154234PMC
November 2016

Changing the Paradigm—Multistage Multiarm Randomized Trials and Stratified Cancer Medicine.

Oncologist 2015 Aug 12;20(8):849-51. Epub 2015 Jun 12.

Cancer Research UK/Medical Research Council Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1634/theoncologist.2015-0014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524758PMC
August 2015

Pathological grading of regression following neoadjuvant chemoradiation therapy: the clinical need is now.

J Clin Pathol 2012 Oct 25;65(10):867-71. Epub 2012 Jun 25.

Oncology Department, Old Road Research Campus Building, Oxford, United Kingdom, OX3 7DQ.

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http://dx.doi.org/10.1136/jclinpath-2012-200958DOI Listing
October 2012

Cetuximab therapy in first-line metastatic colorectal cancer and intermittent palliative chemotherapy: review of the COIN trial.

Expert Rev Anticancer Ther 2008 Aug;8(8):1237-45

Velindre Hospital Cancer Centre, Velindre Road, Whitchurch, Cardiff, CF14 2TL, UK.

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http://www.tandfonline.com/doi/full/10.1586/14737140.8.8.123
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http://dx.doi.org/10.1586/14737140.8.8.1237DOI Listing
August 2008

Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer.

Expert Rev Anticancer Ther 2007 Apr;7(4):503-18

Clinical Oncology, Velindre Hospital, South East Wales Cancer Centre, Whitchurch, Cardiff, South Glamorgan, UK.

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http://dx.doi.org/10.1586/14737140.7.4.503DOI Listing
April 2007