Publications by authors named "Tim J Yen"

38Publications

OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases.

PLoS One 2016 15;11(4):e0153518. Epub 2016 Apr 15.

Department of Biological Sciences, University of Toledo, Toledo, Ohio, United States of America.

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August 2016

Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet).

Proc Natl Acad Sci U S A 2014 Aug 4;111(33):12019-24. Epub 2014 Aug 4.

Unit of Biochemistry, The Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel;

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August 2014

Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing protein.

J Biol Chem 2014 Aug 10;289(34):23928-37. Epub 2014 Jul 10.

From the Department of Biological Sciences, University of Toledo, Toledo, Ohio 43606,

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August 2014

Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

Dev Cell 2011 Dec 1;21(6):1077-91. Epub 2011 Dec 1.

Women's Cancer Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.

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December 2011

Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases.

Clin Chim Acta 2011 Nov 24;412(23-24):2267-71. Epub 2011 Aug 24.

Departamento de Biomedicina, Biotecnología y Salud Pública, Facultad de Ciencias, 11510 Puerto Real, Cádiz, Spain.

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November 2011

Autoantibody to NA14 is an independent marker primarily for Sjogren's syndrome.

Front Biosci (Landmark Ed) 2009 Jan 1;14:3733-9. Epub 2009 Jan 1.

Department of Rheumatology and Internal Medicine, Juntendo University Urayasu hospital, Institute for Environment and Gender Specific Medicine, Juntendo University Graduate School of Medicine, Chiba, Japan.

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January 2009

p53-dependent apoptosis in response to spindle damage is linked to loss of Bub1.

Cancer Biol Ther 2009 Apr 11;8(7):645-7. Epub 2009 Apr 11.

Fox Chase Cancer Center, Philadelphia, PA, USA.

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April 2009

Cohesin associates with spindle poles in a mitosis-specific manner and functions in spindle assembly in vertebrate cells.

Mol Biol Cell 2009 Mar 30;20(5):1289-301. Epub 2008 Dec 30.

Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700, USA.

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March 2009

Mitotic checkpoint, aneuploidy and cancer.

Adv Exp Med Biol 2005 ;570:477-99

Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

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September 2008

Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20.

Proc Natl Acad Sci U S A 2008 Jul 30;105(27):9181-5. Epub 2008 Jun 30.

Unit of Biochemistry, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.

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July 2008

Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint.

Cancer Res 2008 May;68(10):3724-32

Fox Chase Cancer Center, Department of Pathology, Children's Hospital of Philadelphia, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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May 2008

SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis.

Mol Cell 2008 Mar;29(6):729-41

Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA.

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March 2008

Astrin regulates Aurora-A localization.

Biochem Biophys Res Commun 2008 May 24;370(2):213-9. Epub 2008 Mar 24.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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May 2008

Polo delivers a PICH to the kinetochore.

Authors:
Tim J Yen

Cell 2007 Jan;128(1):20-1

Fox Chase Cancer Center, Philadelphia, PA 19083, USA.

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January 2007

Kinetochore structure and function.

Trends Cell Biol 2005 Nov 7;15(11):589-98. Epub 2005 Oct 7.

Department of Oncology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada T6G 1Z2.

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November 2005

Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B.

Biochim Biophys Acta 2005 Jun 17;1744(2):89-92. Epub 2005 Feb 17.

Dept. of Pathology, Children's Hospital of Philadelphia, PA 19104, USA.

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June 2005