Tim Forshew

Tim Forshew

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Tim Forshew

Tim Forshew

Publications by authors named "Tim Forshew"

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Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246.

Nat Commun 2018 02 22;9(1):771. Epub 2018 Feb 22.

Laboratory of Human Carcinogenesis, NCI-CCR, National Institutes of Health, Bethesda, 20892-4258, MD, USA.

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http://dx.doi.org/10.1038/s41467-018-03224-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823939PMC
February 2018

Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways.

Acta Neuropathol Commun 2015 Dec 18;3:86. Epub 2015 Dec 18.

Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.

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http://dx.doi.org/10.1186/s40478-015-0266-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683939PMC
December 2015

Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma.

Genes Chromosomes Cancer 2014 Jan 29;53(1):38-51. Epub 2013 Oct 29.

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1002/gcc.22116DOI Listing
January 2014

Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro.

Cancer Res 2013 Sep 25;73(18):5834-44. Epub 2013 Jul 25.

Authors' Affiliations: Division of Neuropathology, Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London; Department of Histopathology, Neural Development Unit, and UCL Genomics, UCL Institute of Child Health, Great Ormond Street Hospital, London; and Children's Brain Tumour Research Centre, Queen's Medical Centre, Nottingham, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1299DOI Listing
September 2013

Analysis of circulating tumor DNA to monitor metastatic breast cancer.

N Engl J Med 2013 Mar 13;368(13):1199-209. Epub 2013 Mar 13.

Department of Oncology, University of Cambridge and Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa1213261DOI Listing
March 2013

RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology.

Genome Res 2011 Apr 10;21(4):505-14. Epub 2011 Mar 10.

Queen Mary University of London, Centre for Neuroscience and Trauma, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, United Kingdom.

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http://dx.doi.org/10.1101/gr.115782.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065698PMC
April 2011

MAPK pathway activation and the origins of pediatric low-grade astrocytomas.

J Cell Physiol 2010 Mar;222(3):509-14

Queen Mary University of London, Centre for Neuroscience and Trauma, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1002/jcp.21978DOI Listing
March 2010

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

J Pathol 2009 Jun;218(2):172-81

Neuroscience Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Institute of Cell and Molecular Science, London, UK.

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http://doi.wiley.com/10.1002/path.2558
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http://dx.doi.org/10.1002/path.2558DOI Listing
June 2009

Replication timing profile reflects the distinct functional and genomic features of the MHC class II region.

Cell Cycle 2007 Oct 17;6(19):2393-8. Epub 2007 Oct 17.

Human Cytogenetics Laboratory, Cancer Research, UK London Research Institute, London, UK.

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http://dx.doi.org/10.4161/cc.6.19.4762DOI Listing
October 2007

Locus heterogeneity in autosomal recessive congenital cataracts: linkage to 9q and germline HSF4 mutations.

Hum Genet 2005 Sep 16;117(5):452-9. Epub 2005 Jun 16.

Section of Medical and Molecular Genetics, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

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http://link.springer.com/content/pdf/10.1007/s00439-005-1309
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http://link.springer.com/10.1007/s00439-005-1309-9
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http://dx.doi.org/10.1007/s00439-005-1309-9DOI Listing
September 2005