Publications by authors named "Tilmann Bochtler"

41Publications

RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.

Authors:
Anna L Brown Peer Arts Catherine L Carmichael Milena Babic Julia Dobbins Chan-Eng Chong Andreas W Schreiber Jinghua Feng Kerry Phillips Paul P S Wang Thuong Ha Claire C Homan Sarah L King-Smith Lesley Rawlings Cassandra Vakulin Andrew Dubowsky Jessica Burdett Sarah Moore Grace McKavanagh Denae Henry Amanda Wells Belinda Mercorella Mario Nicola Jeffrey Suttle Ella Wilkins Xiao-Chun Li Joelle Michaud Peter Brautigan Ping Cannon Meryl Altree Louise Jaensch Miriam Fine Carolyn Butcher Richard J D'Andrea Ian D Lewis Devendra K Hiwase Elli Papaemmanuil Marshall S Horwitz Georges Natsoulis Hugh Y Rienhoff Nigel Patton Sally Mapp Rachel Susman Susan Morgan Julian Cooney Mark Currie Uday Popat Tilmann Bochtler Shai Izraeli Kenneth Bradstock Lucy A Godley Alwin Krämer Stefan Fröhling Andrew H Wei Cecily Forsyth Helen Mar Fan Nicola K Poplawski Christopher N Hahn Hamish S Scott

Blood Adv 2020 03;4(6):1131-1144

Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, SA, Australia.

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March 2020

Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary.

Authors:
Tilmann Bochtler Anna Reiling Volker Endris Thomas Hielscher Anna-Lena Volckmar Olaf Neumann Martina Kirchner Jan Budczies Lukas C Heukamp Jonas Leichsenring Michael Allgäuer Daniel Kazdal Harald Löffler Wilko Weichert Peter Schirmacher Albrecht Stenzinger Alwin Krämer

Int J Cancer 2020 06 11;146(11):3053-3064. Epub 2020 Mar 11.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.

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June 2020

RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples.

Authors:
Martina Kirchner Olaf Neumann Anna-Lena Volckmar Fabian Stögbauer Michael Allgäuer Daniel Kazdal Jan Budczies Eugen Rempel Regine Brandt Suranand Babu Talla Moritz von Winterfeld Jonas Leichsenring Tilmann Bochtler Alwin Krämer Christoph Springfeld Peter Schirmacher Roland Penzel Volker Endris Albrecht Stenzinger

Cancers (Basel) 2019 Sep 5;11(9). Epub 2019 Sep 5.

Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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September 2019

TP53 deficiency permits chromosome abnormalities and karyotype heterogeneity in acute myeloid leukemia.

Authors:
Anna Cazzola Christin Schlegel Ilka Jansen Tilmann Bochtler Anna Jauch Alwin Krämer

Leukemia 2019 11 23;33(11):2619-2627. Epub 2019 Aug 23.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.

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November 2019

Does Cancer of Unknown Primary (CUP) Truly Exist as a Distinct Cancer Entity?

Authors:
Tilmann Bochtler Alwin Krämer

Front Oncol 2019 17;9:402. Epub 2019 May 17.

Clinical Cooperation Unit Molecular Hematology/Oncology, Department of Internal Medicine V, German Cancer Research Center, University Hospital Heidelberg, Heidelberg, Germany.

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May 2019

In Reply.

Authors:
Tilmann Bochtler

Dtsch Arztebl Int 2019 04;116(14):251

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April 2019

Fludarabine-treosulfan compared to thiotepa-busulfan-fludarabine or FLAMSA as conditioning regimen for patients with primary refractory or relapsed acute myeloid leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT).

Authors:
Francesco Saraceni Myriam Labopin Arne Brecht Nicolaus Kröger Matthias Eder Johanna Tischer Hélène Labussière-Wallet Hermann Einsele Dietrich Beelen Donald Bunjes Dietger Niederwieser Tilmann Bochtler Bipin N Savani Mohamad Mohty Arnon Nagler

J Hematol Oncol 2019 04 25;12(1):44. Epub 2019 Apr 25.

EBMT Paris study office- CEREST-TC, Paris, France, Department of Haematology, Saint Antoine Hospital, Paris, France.

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April 2019

Comparative genetic profiling aids diagnosis and clinical decision making in challenging cases of CUP syndrome.

Authors:
Tilmann Bochtler Volker Endris Jonas Leichsenring Anna Reiling Olaf Neumann Anna-Lena Volckmar Martina Kirchner Michael Allgäuer Peter Schirmacher Alwin Krämer Albrecht Stenzinger

Int J Cancer 2019 12 29;145(11):2963-2973. Epub 2019 Apr 29.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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December 2019

Hematological Malignancies in Adults With a Family Predisposition.

Authors:
Tilmann Bochtler Georg-Martin Haag Sarah Schott Matthias Kloor Alwin Krämer Carsten Müller-Tidow

Dtsch Arztebl Int 2018 12;115(50):848-854

Department of Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital and Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) Heidelberg, Germany; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany; Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany; Section Head of Translational Gynecology, University Women's Hospital Heidelberg, German Cancer Consortium (DKTK), Heidelberg, Germany; Institute of Pathology, Department of Applied Tumor Biology, Heidelberg University Hospital, Heidelberg, Germany.

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December 2018

Performance analysis of AL amyloidosis cardiac biomarker staging systems with special focus on renal failure and atrial arrhythmia.

Authors:
Tobias Dittrich Axel Benner Christoph Kimmich Fabian Aus dem Siepen Kaya Veelken Arnt V Kristen Tilmann Bochtler Hugo A Katus Carsten Müller-Tidow Ute Hegenbart Stefan O Schönland

Haematologica 2019 07 17;104(7):1451-1459. Epub 2019 Jan 17.

Department of Internal Medicine V, Division of Hematology/Oncology, Heidelberg University Hospital

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July 2019

Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial.

Authors:
Uwe Platzbecker Jan Moritz Middeke Katja Sockel Regina Herbst Dominik Wolf Claudia D Baldus Uta Oelschlägel Anke Mütherig Lars Fransecky Richard Noppeney Gesine Bug Katharina S Götze Alwin Krämer Tilmann Bochtler Matthias Stelljes Christoph Groth Antje Schubert Marika Mende Friedrich Stölzel Christine Borkmann Anne Sophie Kubasch Malte von Bonin Hubert Serve Mathias Hänel Ulrich Dührsen Johannes Schetelig Christoph Röllig Michael Kramer Gerhard Ehninger Martin Bornhäuser Christian Thiede

Lancet Oncol 2018 12 12;19(12):1668-1679. Epub 2018 Nov 12.

Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.

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December 2018

Micronucleus formation in human cancer cells is biased by chromosome size.

Authors:
Tilmann Bochtler Mutlu Kartal-Kaess Martin Granzow Thomas Hielscher Marco R Cosenza Christel Herold-Mende Anna Jauch Alwin Krämer

Genes Chromosomes Cancer 2019 06 17;58(6):392-395. Epub 2019 Jan 17.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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June 2019

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma.

Authors:
Tilmann Bochtler Maximilian Merz Thomas Hielscher Martin Granzow Korbinian Hoffmann Alwin Krämer Marc-Steffen Raab Jens Hillengass Anja Seckinger Christoph Kimmich Tobias Dittrich Carsten Müller-Tidow Dirk Hose Hartmut Goldschmidt Ute Hegenbart Anna Jauch Stefan O Schönland

Blood Adv 2018 10;2(20):2607-2618

Department of Medicine V, Hematology/Oncology/Rheumatology, University of Heidelberg, Heidelberg, Germany.

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October 2018

Treatment of AL amyloidosis with bendamustine: a study of 122 patients.

Authors:
Paolo Milani Stefan Schönland Giampaolo Merlini Christoph Kimmich Andrea Foli Tobias Dittrich Marco Basset Carsten Müller-Tidow Tilmann Bochtler Giovanni Palladini Ute Hegenbart

Blood 2018 11 14;132(18):1988-1991. Epub 2018 Aug 14.

Department of Internal Medicine V, Hematology/Oncology/Rheumatology, Amyloidosis Center, University of Heidelberg, Heidelberg, Germany.

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November 2018

Enasidenib.

Authors:
Alwin Krämer Tilmann Bochtler

Recent Results Cancer Res 2018;212:187-197

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), University of Heidelberg, Heidelberg, Germany.

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May 2019

Integrated Histogenetic Analysis Reveals -Mutated Epithelioid Mesothelioma in a Patient With Cancer of Unknown Primary.

Authors:
Tilmann Bochtler Volker Endris Anna Reiling Jonas Leichsenring Michal R Schweiger Sebastian Klein Fabian Stögbauer Benjamin Goeppert Peter Schirmacher Alwin Krämer Albrecht Stenzinger

J Natl Compr Canc Netw 2018 06;16(6):677-682

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June 2018

Phase I dose-escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia.

Authors:
Oliver G Ottmann Carsten Müller-Tidow Alwin Krämer Richard F Schlenk Michael Lübbert Gesine Bug Utz Krug Tilmann Bochtler Florian Voss Tillmann Taube Dan Liu Pilar Garin-Chesa Hartmut Döhner

Br J Haematol 2019 03 8;184(6):1018-1021. Epub 2018 Jun 8.

Department of Internal Medicine III, University of Ulm, Ulm, Germany.

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March 2019

Prognostic significance of cytogenetic heterogeneity in patients with newly diagnosed multiple myeloma.

Authors:
Maximilian Merz Anna Jauch Thomas Hielscher Tilmann Bochtler Stefan Olaf Schönland Anja Seckinger Dirk Hose Uta Bertsch Kai Neben Marc Steffen Raab Jens Hillengass Hans Salwender Igor Wolfgang Blau Hans-Walter Lindemann Ingo G H Schmidt-Wolf Christof Scheid Mathias Haenel Katja C Weisel Hartmut Goldschmidt

Blood Adv 2018 01 27;2(1):1-9. Epub 2017 Dec 27.

Medizinische Klinik V and.

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January 2018

Diagnosis and management of metastatic neoplasms with unknown primary.

Authors:
Tilmann Bochtler Harald Löffler Alwin Krämer

Semin Diagn Pathol 2018 May 26;35(3):199-206. Epub 2017 Nov 26.

Clinical Cooperation Unit Molecular Hematology / Oncology, German Cancer Research Center (DKFZ) and Department of Medicine V, University of Heidelberg, Heidelberg, Germany; Department of Internal Medicine V, Hematology / Oncology, University of Heidelberg, Heidelberg, Germany. Electronic address:

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May 2018

Mesenchymal stromal cells contribute to quiescence of therapy-resistant leukemic cells in acute myeloid leukemia.

Authors:
Wenwen Wang Tilmann Bochtler Patrick Wuchter Linda Manta Haiju He Volker Eckstein Anthony D Ho Christoph Lutz

Eur J Haematol 2017 Nov 13;99(5):392-398. Epub 2017 Sep 13.

Department of Medicine V, University of Heidelberg, Heidelberg, Germany.

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November 2017

Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia.

Authors:
Wenwen Wang Thomas Stiehl Simon Raffel Van T Hoang Isabel Hoffmann Laura Poisa-Beiro Borhan R Saeed Rachel Blume Linda Manta Volker Eckstein Tilmann Bochtler Patrick Wuchter Marieke Essers Anna Jauch Andreas Trumpp Anna Marciniak-Czochra Anthony D Ho Christoph Lutz

Haematologica 2017 09 26;102(9):1567-1577. Epub 2017 May 26.

Department of Medicine V, Heidelberg University, Germany

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September 2017

AL amyloidosis patients with low amyloidogenic free light chain levels at first diagnosis have an excellent prognosis.

Authors:
Tobias Dittrich Tilmann Bochtler Christoph Kimmich Natalia Becker Anna Jauch Hartmut Goldschmidt Anthony D Ho Ute Hegenbart Stefan O Schönland

Blood 2017 08 26;130(5):632-642. Epub 2017 May 26.

Amyloidosis Center and.

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August 2017

Lenalidomide/melphalan/dexamethasone in newly diagnosed patients with immunoglobulin light chain amyloidosis: results of a prospective phase 2 study with long-term follow up.

Authors:
Ute Hegenbart Tilmann Bochtler Axel Benner Natalia Becker Christoph Kimmich Arnt V Kristen Jörg Beimler Ernst Hund Markus Zorn Anja Freiberger Marianne Gawlik Hartmut Goldschmidt Dirk Hose Anna Jauch Anthony D Ho Stefan O Schönland

Haematologica 2017 08 18;102(8):1424-1431. Epub 2017 May 18.

Department of Internal Medicine, Division of Hematology/Oncology, University of Heidelberg, Germany.

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August 2017

Response to bendamustine is associated with a survival advantage in a heavily pretreated patients with AL amyloidosis.

Authors:
Paolo Milani Stefan Schönland Giovanni Palladini Christoph Kimmich Marco Basset Francesca Russo Andrea Foli Stefano Perlini Tilmann Bochtler Anthony D Ho Giampaolo Merlini Ute Hegenbart

Amyloid 2017 03;24(sup1):56-57

c Amyloidosis Center, University Hospital Heidelberg , Heidelberg , Germany.

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March 2017

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis.

Authors:
Martin Granzow Ute Hegenbart Katrin Hinderhofer Dirk Hose Anja Seckinger Tilmann Bochtler Kari Hemminki Hartmut Goldschmidt Stefan O Schönland Anna Jauch

Haematologica 2017 07 24;102(7):1281-1290. Epub 2017 Mar 24.

Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.

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July 2017

Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia.

Authors:
Tilmann Bochtler Martin Granzow Friedrich Stölzel Christina Kunz Brigitte Mohr Mutlu Kartal-Kaess Katrin Hinderhofer Christoph E Heilig Michael Kramer Christian Thiede Volker Endris Martina Kirchner Albrecht Stenzinger Axel Benner Martin Bornhäuser Gerhard Ehninger Anthony D Ho Anna Jauch Alwin Krämer

Blood 2017 03 24;129(10):1333-1342. Epub 2017 Jan 24.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center.

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March 2017

Evolution of a FLT3-TKD mutated subclone at meningeal relapse in acute promyelocytic leukemia.

Authors:
Tilmann Bochtler Stefan Fröhling Wilko Weichert Volker Endris Christian Thiede Barbara Hutter Michael Hundemer Anthony D Ho Alwin Krämer

Cold Spring Harb Mol Case Stud 2016 Sep;2(5):a001123

Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany;; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany;

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September 2016

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study.

Authors:
Tilmann Bochtler Ute Hegenbart Christina Kunz Axel Benner Christoph Kimmich Anja Seckinger Dirk Hose Hartmut Goldschmidt Martin Granzow Peter Dreger Anthony D Ho Anna Jauch Stefan O Schönland

Blood 2016 07 2;128(4):594-602. Epub 2016 Jun 2.

Amyloidosis Center, and Division of Hematology/Oncology/Rheumatology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany;

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July 2016

Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD.

Authors:
Anthony D Ho Johannes Schetelig Tilmann Bochtler Markus Schaich Kerstin Schäfer-Eckart Mathias Hänel Wolf Rösler Hermann Einsele Martin Kaufmann Hubert Serve Wolfgang E Berdel Matthias Stelljes Jiri Mayer Albrecht Reichle Claudia D Baldus Norbert Schmitz Michael Kramer Christoph Röllig Martin Bornhäuser Christian Thiede Gerhard Ehninger

Biol Blood Marrow Transplant 2016 Mar 10;22(3):462-9. Epub 2015 Nov 10.

Medizinische Klinik und Poliklinik I, TU Dresden, Dresden, Germany.

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March 2016

Reply to R. Warsame et al.

Authors:
Tilmann Bochtler Ute Hegenbart Christina Kunz Axel Benner Stefan O Schönland

J Clin Oncol 2015 Nov 31;33(33):3976-7. Epub 2015 Aug 31.

University of Heidelberg, Heidelberg, Germany

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November 2015

Translocation t(11;14) is associated with adverse outcome in patients with newly diagnosed AL amyloidosis when treated with bortezomib-based regimens.

Authors:
Tilmann Bochtler Ute Hegenbart Christina Kunz Martin Granzow Axel Benner Anja Seckinger Christoph Kimmich Hartmut Goldschmidt Anthony D Ho Dirk Hose Anna Jauch Stefan O Schönland

J Clin Oncol 2015 Apr 16;33(12):1371-8. Epub 2015 Mar 16.

Tilmann Bochtler, Ute Hegenbart, Anja Seckinger, Christoph Kimmich, Hartmut Goldschmidt, Anthony D. Ho, Dirk Hose, and Stefan O. Schönland, Amyloidosis Center, University Hospital Heidelberg; Christina Kunz and Axel Benner, German Cancer Research Center; Martin Granzow and Anna Jauch, Institute of Human Genetics, University Heidelberg; and Hartmut Goldschmidt and Dirk Hose, National Center for Tumor Diseases, Heidelberg, Germany.

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April 2015

Outcome of patients with abnl(17p) acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation.

Authors:
Jan M Middeke Min Fang Jan J Cornelissen Brigitte Mohr Frederick R Appelbaum Michael Stadler Jaime Sanz Herrad Baurmann Gesine Bug Kerstin Schäfer-Eckart Ute Hegenbart Tilmann Bochtler Christoph Röllig Friedrich Stölzel Roland B Walter Gerhard Ehninger Martin Bornhäuser Bob Löwenberg Johannes Schetelig

Blood 2014 May 20;123(19):2960-7. Epub 2014 Mar 20.

Universitätsklinikum Carl Gustav Carus der Technische Universität Dresden, Medizinische Klinik und Poliklinik I, Dresden, Germany;

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May 2014

Azacitidine and low-dose cytarabine in palliative patients with acute myeloid leukemia and high bone marrow blast counts--a retrospective single-center experience.

Authors:
Aleksandar Radujkovic Sascha Dietrich Tilmann Bochtler Alwin Krämer Tilman Schöning Anthony D Ho Peter Dreger Thomas Luft

Eur J Haematol 2014 Aug 3;93(2):112-7. Epub 2014 Apr 3.

Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.

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August 2014

Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone.

Authors:
Tilmann Bochtler Ute Hegenbart Christina Kunz Axel Benner Anja Seckinger Sascha Dietrich Martin Granzow Kai Neben Hartmut Goldschmidt Anthony D Ho Dirk Hose Anna Jauch Stefan O Schönland

Amyloid 2014 Mar 23;21(1):9-17. Epub 2014 Jan 23.

Amyloidosis Center, Department of Internal Medicine, University of Heidelberg , Heidelberg, Germany .

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March 2014

Clonal heterogeneity as detected by metaphase karyotyping is an indicator of poor prognosis in acute myeloid leukemia.

Authors:
Tilmann Bochtler Friedrich Stölzel Christoph E Heilig Christina Kunz Brigitte Mohr Anna Jauch Johannes W G Janssen Michael Kramer Axel Benner Martin Bornhäuser Anthony D Ho Gerhard Ehninger Markus Schaich Alwin Krämer

J Clin Oncol 2013 Nov 23;31(31):3898-905. Epub 2013 Sep 23.

Tilmann Bochtler, Christoph E. Heilig, Anna Jauch, Johannes W.G. Janssen, Anthony D. Ho, and Alwin Krämer, University of Heidelberg; Tilmann Bochtler, Christina Kunz, Axel Benner, and Alwin Krämer, German Cancer Research Center (DKFZ), Heidelberg; and Friedrich Stölzel, Brigitte Mohr, Michael Kramer, Martin Bornhäuser, Gerhard Ehninger, and Markus Schaich, University Hospital Carl Gustav Carus, Dresden, Germany.

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November 2013

Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients.

Authors:
Stefan O Schönland Ute Hegenbart Tilmann Bochtler Anja Mangatter Marion Hansberg Anthony D Ho Peter Lohse Christoph Röcken

Blood 2012 Jan 21;119(2):488-93. Epub 2011 Nov 21.

Medical Department V, Amyloidosis Center, University of Heidelberg, Germany.

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January 2012

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).

Authors:
Tilmann Bochtler Ute Hegenbart Christiane Heiss Axel Benner Marion Moos Anja Seckinger Stephanie Pschowski-Zuck Désirée Kirn Kai Neben Claus R Bartram Anthony D Ho Hartmut Goldschmidt Dirk Hose Anna Jauch Stefan O Schonland

Blood 2011 Apr 10;117(14):3809-15. Epub 2011 Feb 10.

Amyloidosis Center, Department of Internal Medicine, Division of Hematology/Oncology/Rheumatology, University of Heidelberg, Heidelberg, Germany.

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April 2011

Treatment with intravenous melphalan and dexamethasone is not able to overcome the poor prognosis of patients with newly diagnosed systemic light chain amyloidosis and severe cardiac involvement.

Authors:
Sascha Dietrich Stefan O Schönland Axel Benner Tilmann Bochtler Arnt V Kristen Jörg Beimler Ernst Hund Markus Zorn Hartmut Goldschmidt Antony D Ho Ute Hegenbart

Blood 2010 Jul 7;116(4):522-8. Epub 2010 Apr 7.

Division of Hematology/Oncology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany.

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July 2010

Evaluation of the cytogenetic aberration pattern in amyloid light chain amyloidosis as compared with monoclonal gammopathy of undetermined significance reveals common pathways of karyotypic instability.

Authors:
Tilmann Bochtler Ute Hegenbart Friedrich W Cremer Christiane Heiss Axel Benner Dirk Hose Marion Moos Jelena Bila Claus R Bartram Anthony D Ho Hartmut Goldschmidt Anna Jauch Stefan O Schonland

Blood 2008 May 27;111(9):4700-5. Epub 2008 Feb 27.

Department of Internal Medicine, Division of Hematology/Oncology, Amyloidosis Clinic, University of Heidelberg, Heidelberg, Germany.

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May 2008

Evaluation of the serum-free light chain test in untreated patients with AL amyloidosis.

Authors:
Tilmann Bochtler Ute Hegenbart Christiane Heiss Axel Benner Friedrich Cremer Martin Volkmann Jochen Ludwig Jolanta B Perz Anthony D Ho Hartmut Goldschmidt Stefan O Schonland

Haematologica 2008 Mar 20;93(3):459-62. Epub 2008 Feb 20.

Department of Internal Medicine Division of Hematology/Oncology, Amyloidosis Clinic, University of Heidelberg, Germany.

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March 2008

DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function.

Authors:
Harald Löffler Tilmann Bochtler Britta Fritz Björn Tews Anthony D Ho Jiri Lukas Jiri Bartek Alwin Krämer

Cell Cycle 2007 Oct 30;6(20):2541-8. Epub 2007 Jul 30.

Clinical Cooperation Unit for Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.

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October 2007