Publications by authors named "Tilman T Rau"

56Publications

Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer.

J Clin Oncol 2020 Sep 8:JCO1903205. Epub 2020 Sep 8.

INSERM, Laboratory of Integrative Cancer Immunology, Paris, France.

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http://dx.doi.org/10.1200/JCO.19.03205DOI Listing
September 2020

Prognostic impact of tumor budding in endometrial carcinoma within distinct molecular subgroups.

Mod Pathol 2020 Jul 29. Epub 2020 Jul 29.

Institute of Pathology, University Bern Murtenstrasse 31, 3008, Bern, Switzerland.

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http://dx.doi.org/10.1038/s41379-020-0626-9DOI Listing
July 2020

Editorial: Computational Pathology.

Front Med (Lausanne) 2020 9;7:245. Epub 2020 Jun 9.

École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fmed.2020.00245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295903PMC
June 2020

Inter-observer reproducibility of classical lobular neoplasia (B3 lesions) in preoperative breast biopsies: a study of the Swiss Working Group of breast and gynecopathologists.

J Cancer Res Clin Oncol 2020 Jun 30;146(6):1473-1478. Epub 2020 Mar 30.

Institute of Pathology and Molecular Pathology, University Hospital Zurich, Schmelzbergstrasse 12, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00432-020-03195-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230045PMC
June 2020

Interpretation of somatic POLE mutations in endometrial carcinoma.

J Pathol 2020 03 29;250(3):323-335. Epub 2020 Jan 29.

Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1002/path.5372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065171PMC
March 2020

Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells.

J Cancer Res Clin Oncol 2019 Sep 17;145(9):2227-2240. Epub 2019 Jul 17.

Experimental Tumorpathology, Institute of Pathology, Friedrich-Alexander-University of Erlangen-Nürnberg, Universitätsstr. 22, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00432-019-02977-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708512PMC
September 2019

Phenotype of POLE-mutated endometrial cancer.

PLoS One 2019 27;14(3):e0214318. Epub 2019 Mar 27.

Department of Oncology-Pathology, Karolinska Institutet, and Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214318PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436745PMC
December 2019

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.

Authors:
Franck Pagès Bernhard Mlecnik Florence Marliot Gabriela Bindea Fang-Shu Ou Carlo Bifulco Alessandro Lugli Inti Zlobec Tilman T Rau Martin D Berger Iris D Nagtegaal Elisa Vink-Börger Arndt Hartmann Carol Geppert Julie Kolwelter Susanne Merkel Robert Grützmann Marc Van den Eynde Anne Jouret-Mourin Alex Kartheuser Daniel Léonard Christophe Remue Julia Y Wang Prashant Bavi Michael H A Roehrl Pamela S Ohashi Linh T Nguyen SeongJun Han Heather L MacGregor Sara Hafezi-Bakhtiari Bradly G Wouters Giuseppe V Masucci Emilia K Andersson Eva Zavadova Michal Vocka Jan Spacek Lubos Petruzelka Bohuslav Konopasek Pavel Dundr Helena Skalova Kristyna Nemejcova Gerardo Botti Fabiana Tatangelo Paolo Delrio Gennaro Ciliberto Michele Maio Luigi Laghi Fabio Grizzi Tessa Fredriksen Bénédicte Buttard Mihaela Angelova Angela Vasaturo Pauline Maby Sarah E Church Helen K Angell Lucie Lafontaine Daniela Bruni Carine El Sissy Nacilla Haicheur Amos Kirilovsky Anne Berger Christine Lagorce Jeffrey P Meyers Christopher Paustian Zipei Feng Carmen Ballesteros-Merino Jeroen Dijkstra Carlijn van de Water Shannon van Lent-van Vliet Nikki Knijn Ana-Maria Mușină Dragos-Viorel Scripcariu Boryana Popivanova Mingli Xu Tomonobu Fujita Shoichi Hazama Nobuaki Suzuki Hiroaki Nagano Kiyotaka Okuno Toshihiko Torigoe Noriyuki Sato Tomohisa Furuhata Ichiro Takemasa Kyogo Itoh Prabhu S Patel Hemangini H Vora Birva Shah Jayendrakumar B Patel Kruti N Rajvik Shashank J Pandya Shilin N Shukla Yili Wang Guanjun Zhang Yutaka Kawakami Francesco M Marincola Paolo A Ascierto Daniel J Sargent Bernard A Fox Jérôme Galon

Lancet 2018 05 10;391(10135):2128-2139. Epub 2018 May 10.

INSERM, Laboratory of Integrative Cancer Immunology, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Centre de Recherche des Cordeliers, Université Pierre et Marie Curie, Sorbonne Universités, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)30789-XDOI Listing
May 2018

Restoration of an academic historical gross pathology collection-refreshed impact on current medical teaching?

Virchows Arch 2018 Aug 10;473(2):219-228. Epub 2018 May 10.

Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Krankenhausstrasse 8, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00428-018-2369-2DOI Listing
August 2018

Retrospective validation of the laparoscopic ICG SLN mapping in patients with grade 3 endometrial cancer.

J Cancer Res Clin Oncol 2018 Jul 24;144(7):1385-1393. Epub 2018 Apr 24.

Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Effingerstrasse 102, 3010, Bern, Switzerland.

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http://dx.doi.org/10.1007/s00432-018-2648-yDOI Listing
July 2018

Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery.

Cell Host Microbe 2017 Oct;22(4):552-560.e5

Department of Biology, Division of Microbiology, University of Erlangen-Nuremberg, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.09.005DOI Listing
October 2017

Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients.

J Pathol Clin Res 2017 Jan 13;3(1):58-70. Epub 2017 Jan 13.

Institute of PathologyFriedrich Alexander University Erlangen-NurembergErlangenGermany; Institute of PathologyUniversity BernBernSwitzerland.

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http://doi.wiley.com/10.1002/cjp2.62
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http://dx.doi.org/10.1002/cjp2.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259563PMC
January 2017

Cytokine-Induced Modulation of Colorectal Cancer.

Front Oncol 2016 19;6:96. Epub 2016 Apr 19.

Institute of Pathology, University of Bern , Bern , Switzerland.

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http://dx.doi.org/10.3389/fonc.2016.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835502PMC
May 2016

Jejunitis and brown bowel syndrome with multifocal carcinogenesis of the small bowel.

World J Gastroenterol 2015 Sep;21(36):10461-7

Martin Raithel, Alexander F Hagel, Heinz Albrecht, Thomas de Rossi, Eckhart G Hahn, Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen D-91054, Germany.

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http://www.wjgnet.com/1007-9327/full/v21/i36/10461.htm
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http://dx.doi.org/10.3748/wjg.v21.i36.10461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579893PMC
September 2015

Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer.

J Transl Med 2015 Aug 27;13:279. Epub 2015 Aug 27.

Translational Research Unit (TRU), Institute of Pathology, University of Bern, Murtenstrasse 31, 3010, Bern, Switzerland.

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http://dx.doi.org/10.1186/s12967-015-0647-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551690PMC
August 2015

miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis.

Inflamm Bowel Dis 2015 Sep;21(9):2039-51

*Department of Experimental Tumor Pathology, Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany; †Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany; ‡First Department of Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany; Departments of §Urology and ‖Pediatrics and Adolescent Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany; ¶Stratifyer Molecular Pathology GmbH, Cologne, Germany; **Faculty of School of Chemical and Biotechnology, SASTRA University, Thanjavur, India; ††Institute of Pathology, University Regensburg, Regensburg, Germany; and ‡‡Department of Basic Biomedical Sciences, Laboratory of Biology, School of Medicine, University of Athens, Athens, Greece.

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http://dx.doi.org/10.1097/MIB.0000000000000453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603667PMC
September 2015

Interplay between the prostaglandin transporter OATP2A1 and prostaglandin E2-mediated cellular effects.

Cell Signal 2015 Mar 26;27(3):663-72. Epub 2014 Nov 26.

Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Fahrstraße 17, 91054 Erlangen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08986568140038
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http://dx.doi.org/10.1016/j.cellsig.2014.11.027DOI Listing
March 2015

DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells.

J Cell Sci 2014 Dec 6;127(Pt 24):5273-87. Epub 2014 Nov 6.

Department of Experimental Tumor Pathology, Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen 91054, Germany

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http://dx.doi.org/10.1242/jcs.157024DOI Listing
December 2014

Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer.

Mol Cancer 2014 Aug 29;13:201. Epub 2014 Aug 29.

Experimental Tumorpathology, Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.

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http://dx.doi.org/10.1186/1476-4598-13-201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158125PMC
August 2014

Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations.

Int J Cancer 2015 Mar 30;136(6):E559-68. Epub 2014 Aug 30.

Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/ijc.29149DOI Listing
March 2015

Immunohistochemical panel for the diagnosis of Hirschsprung's disease using antibodies to MAP2, calretinin, GLUT1 and S100.

Histopathology 2015 May 30;66(6):824-35. Epub 2015 Jan 30.

Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; Comprehensive Cancer Centre Erlangen - Metropolitan Region Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/his.12527DOI Listing
May 2015

A histopathologic and immunohistochemical study on liquification of human adipose tissue ex vivo.

Aesthetic Plast Surg 2014 Oct 12;38(5):976-84. Epub 2014 Jul 12.

Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00266-014-0371-xDOI Listing
October 2014

IL-9 and its receptor are predominantly involved in the pathogenesis of UC.

Gut 2015 May 23;64(5):743-55. Epub 2014 Jun 23.

Department of Medicine 1, University of Erlangen-Nuremberg, Erlangen, Germany Department of Gastroenterology, Sana Clinic, Ostholstein, Germany.

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http://dx.doi.org/10.1136/gutjnl-2013-305947DOI Listing
May 2015

Piwi-like 1 and 4 gene transcript levels are associated with clinicopathological parameters in renal cell carcinomas.

Biochim Biophys Acta 2014 May 7;1842(5):686-90. Epub 2014 Feb 7.

Department of Urology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.01.014DOI Listing
May 2014

Brown bowel syndrome: a rare complication in diseases associated with long-standing malabsorption.

Digestion 2014 31;89(2):105-9. Epub 2014 Jan 31.

Department of Internal Medicine 1, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1159/000357228DOI Listing
November 2014

Comparative microRNA profiling of prostate carcinomas with increasing tumor stage by deep sequencing.

Mol Cancer Res 2014 Feb 13;12(2):250-63. Epub 2013 Dec 13.

Saarland University Medical School; Department of Virology, Kirrbergerstrasse, Haus 47, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-13-0230DOI Listing
February 2014

Expression and localization of axin 2 in colorectal carcinoma and its clinical implication.

Int J Colorectal Dis 2013 Nov 24;28(11):1469-78. Epub 2013 May 24.

Division of Molecular and Experimental Surgery, University Medical Center Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00384-013-1709-6DOI Listing
November 2013

Substance P- and choline acetyltransferase immunoreactivities in somatostatin-containing, human submucosal neurons.

Histochem Cell Biol 2013 Aug 30;140(2):157-67. Epub 2013 Jan 30.

Institute of Anatomy I, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00418-013-1078-9DOI Listing
August 2013

Circulating regulatory T cells of cancer patients receiving radiochemotherapy may be useful to individualize cancer treatment.

Radiother Oncol 2012 Jul 9;104(1):131-8. Epub 2012 Jun 9.

Department of Radiation Oncology, Friedrich-Alexander-University Erlangen-Nürnberg, Universitätsstrasse 27, Erlangen, Germany.

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http://dx.doi.org/10.1016/j.radonc.2012.05.003DOI Listing
July 2012

Isolation of endothelial cells from human tumors.

Methods Mol Biol 2011 ;731:209-18

Division of Molecular and Experimental Surgery, University Medical Center Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1007/978-1-61779-080-5_18DOI Listing
August 2011

Inflammation in gastric adenocarcinoma of the cardia: how do EBV infection, Her2 amplification and cancer progression influence tumor-infiltrating lymphocytes?

Virchows Arch 2011 Apr 26;458(4):403-11. Epub 2011 Feb 26.

Department of Radiation Oncology, University Hospital Friedrich-Alexander-University of Erlangen-Nuremberg, Universitätsstr. 27, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00428-011-1058-1DOI Listing
April 2011

Expression and localization of the uptake transporters OATP2B1, OATP3A1 and OATP5A1 in non-malignant and malignant breast tissue.

Cancer Biol Ther 2011 Mar 15;11(6):584-91. Epub 2011 Mar 15.

Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.4161/cbt.11.6.14533DOI Listing
March 2011

Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter organic anion-transporting polypeptide 2A1 expressed in human gastroduodenal mucosa.

J Pharmacol Exp Ther 2010 Feb 20;332(2):345-51. Epub 2009 Oct 20.

Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.109.15451
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http://dx.doi.org/10.1124/jpet.109.154518DOI Listing
February 2010