Tillie L Hackett

Tillie L Hackett

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Tillie L Hackett

Tillie L Hackett

Publications by authors named "Tillie L Hackett"

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miR-146a-5p plays an essential role in the aberrant epithelial-fibroblast cross-talk in COPD.

Eur Respir J 2017 05 25;49(5). Epub 2017 May 25.

Dept of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/13993003.02538-2016DOI Listing
May 2017

Heterogeneity of airway wall dimensions in humans: a critical determinant of lung function in asthmatics and nonasthmatics.

Am J Physiol Lung Cell Mol Physiol 2017 Mar 6;312(3):L425-L431. Epub 2017 Jan 6.

Department of Mathematics, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1152/ajplung.00421.2016DOI Listing
March 2017

Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD.

Eur Respir J 2016 08 13;48(2):359-69. Epub 2016 Jul 13.

University of Groningen, University Medical Center Groningen, Dept of Pathology and Medical Biology, Groningen, The Netherlands University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands University of Groningen, University Medical Center Groningen, Dept of Pulmonology, Groningen, The Netherlands These two authors contributed equally to this work.

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http://dx.doi.org/10.1183/13993003.01911-2015DOI Listing
August 2016

Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects.

Part Fibre Toxicol 2016 Jan 13;13. Epub 2016 Jan 13.

Department of Medicine, Division of Respiratory Medicine, Chan-Yeung Centre for Occupational and Environmental Respiratory Disease, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.

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http://dx.doi.org/10.1186/s12989-016-0114-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711081PMC
January 2016

Pathological changes in the COPD lung mesenchyme--novel lessons learned from in vitro and in vivo studies.

Pulm Pharmacol Ther 2014 Dec 18;29(2):121-8. Epub 2014 Apr 18.

Centre for Heart Lung Innovation and Department of Anesthesiology Pharmacology & Therapeutics, University of British Columbia, St Paul's Hospital, 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pupt.2014.04.004DOI Listing
December 2014

A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.

Genome Med 2012 31;4(8):67. Epub 2012 Aug 31.

Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA ; Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA.

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http://dx.doi.org/10.1186/gm367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064320PMC
August 2014

Airway epithelial regulation of pulmonary immune homeostasis and inflammation.

Clin Immunol 2014 Mar 14;151(1):1-15. Epub 2013 Dec 14.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S15216616130032
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http://dx.doi.org/10.1016/j.clim.2013.12.003DOI Listing
March 2014

Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-β1.

PLoS One 2012 30;7(3):e33163. Epub 2012 Mar 30.

UBC James Hogg Research Centre, Institute for Heart+Lung Health, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033163PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316562PMC
August 2012

Mechanical properties of asthmatic airway smooth muscle.

Eur Respir J 2012 Jul 20;40(1):45-54. Epub 2012 Jan 20.

Dept of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1183/09031936.00065411DOI Listing
July 2012

Granzyme K activates protease-activated receptor-1.

PLoS One 2011 30;6(6):e21484. Epub 2011 Jun 30.

Institute for Heart and Lung Health, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021484PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128063PMC
November 2011

Dual organism transcriptomics of airway epithelial cells interacting with conidia of Aspergillus fumigatus.

PLoS One 2011 31;6(5):e20527. Epub 2011 May 31.

UBC James Hogg Research Centre, Institute for HEART+LUNG Health, Providence Health Care, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020527PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105077PMC
October 2011

E-cadherin: gatekeeper of airway mucosa and allergic sensitization.

Trends Immunol 2011 Jun 12;32(6):248-55. Epub 2011 Apr 12.

Department of Pathology & Medical Biology, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.it.2011.03.004DOI Listing
June 2011

Human lung parenchyma but not proximal bronchi produces fibroblasts with enhanced TGF-beta signaling and alpha-SMA expression.

Am J Respir Cell Mol Biol 2010 Dec 8;43(6):641-51. Epub 2010 Jan 8.

UBC James Hogg Research Centre, Heart + Lung Institute, St. Paul's Hospital, 1081 Burrard Street, Vancouver, BC, Canada.

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http://dx.doi.org/10.1165/rcmb.2009-0318OCDOI Listing
December 2010

Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism.

J Virol 2010 Nov 11;84(21):11359-73. Epub 2010 Aug 11.

UBC James Hogg Research Centre, Providence Heart+Lung Institute, Department of Pathology and Laboratory Medicine, University of British Columbia, Room 166, Burrard Building, St. Paul's Hospital, 1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6.

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http://jvi.asm.org/content/84/21/11359.full.pdf
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http://jvi.asm.org/cgi/doi/10.1128/JVI.00804-10
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http://dx.doi.org/10.1128/JVI.00804-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953195PMC
November 2010

Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus.

BMC Genomics 2010 Jun 4;11:358. Epub 2010 Jun 4.

UBC James Hogg Research Centre, Providence Heart + Lung Institute, St, Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1186/1471-2164-11-358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897809PMC
June 2010

Potential role of stem cells in management of COPD.

Int J Chron Obstruct Pulmon Dis 2010 Apr 7;5:81-8. Epub 2010 Apr 7.

UBC James Hogg Research Centre, Heart and Lung Institute, St Paul's Hospital, Vancouver, BC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865028PMC
http://dx.doi.org/10.2147/copd.s7373DOI Listing
April 2010