Publications by authors named "Till Beuerle"

61Publications

A validated HPTLC method for the simultaneous quantifications of three phenolic acids and three withanolides from Withania somnifera plants and its herbal products.

J Chromatogr B Analyt Technol Biomed Life Sci 2019 Aug 6;1124:154-160. Epub 2019 Jun 6.

Plant Molecular Biology Group, Biotechnology Department, Indian Institute of Technology Roorkee, Roorkee 247667, India. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2019.06.009DOI Listing
August 2019

HILIC HPLC-ESI-MS/MS identification and quantification of the alkaloids from the genus Equisetum.

Phytochem Anal 2019 Nov 22;30(6):669-678. Epub 2019 May 22.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstr, Braunschweig, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pca.2840
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http://dx.doi.org/10.1002/pca.2840DOI Listing
November 2019

Quantitative and qualitative analysis of pyrrolizidine alkaloids in liqueurs, elixirs and herbal juices.

Fitoterapia 2019 Jul 14;136:104172. Epub 2019 May 14.

Technische Universität Braunschweig, Institut für Pharmazeutische Biologie, Mendelssohnstr. 1, Braunschweig 38106, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.104172DOI Listing
July 2019

Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: Update of the German situation in summer 2018.

Forensic Sci Int 2019 Jan 15;294:96-102. Epub 2018 Nov 15.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2018.11.001DOI Listing
January 2019

Uncertainties in the determination of pyrrolizidine alkaloid levels in naturally contaminated honeys and comparison of results obtained by different analytical approaches.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2018 Jul 7;35(7):1366-1383. Epub 2018 Jun 7.

d Institut für Pharmazeutische Biologie , Technische Universität Braunschweig (TUB) , Braunschweig , Germany.

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http://dx.doi.org/10.1080/19440049.2018.1468929DOI Listing
July 2018

Incidence of Pyrrolizidine Alkaloids in Herbal Medicines from German Retail Markets: Risk Assessments and Implications to Consumers.

Phytother Res 2017 Dec 28;31(12):1903-1909. Epub 2017 Sep 28.

Institute of Pharmaceutical Biology, Technische Universitat Carolo Wilhelmina zu Braunschweig, Braunschweig, Niedersachsen, Germany.

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http://dx.doi.org/10.1002/ptr.5935DOI Listing
December 2017

Determination of cross-reactivity of poly- and monoclonal antibodies for synthetic cannabinoids by direct SPR and ELISA.

Forensic Sci Int 2017 Nov 18;280:25-34. Epub 2017 Sep 18.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2017.09.011DOI Listing
November 2017

Pyrrolizidine alkaloids in floral honeys of tropical Ghana: a health risk assessment.

Food Addit Contam Part B Surveill 2017 Dec 16;10(4):300-310. Epub 2017 Jul 16.

d Institut für Pharmazeutische Biologie , Technische Universität Braunschweig , Braunschweig , Germany.

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http://dx.doi.org/10.1080/19393210.2017.1354336DOI Listing
December 2017

Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: Update of the German situation in early 2017.

Forensic Sci Int 2017 Aug 26;277:51-58. Epub 2017 May 26.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2017.05.019DOI Listing
August 2017

Toxic pyrrolizidine alkaloids in herbal medicines commonly used in Ghana.

J Ethnopharmacol 2017 Apr 8;202:154-161. Epub 2017 Mar 8.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstrasse 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.03.008DOI Listing
April 2017

Identification and quantification of synthetic cannabinoids in "spice-like" herbal mixtures: Update of the German situation for the spring of 2016.

Forensic Sci Int 2016 Dec 4;269:31-41. Epub 2016 Nov 4.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2016.10.023DOI Listing
December 2016

Bifunctional CYP81AA proteins catalyse identical hydroxylations but alternative regioselective phenol couplings in plant xanthone biosynthesis.

Nat Commun 2016 05 5;7:11472. Epub 2016 May 5.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstraße 1, Braunschweig 38106, Germany.

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http://www.nature.com/articles/ncomms11472
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http://dx.doi.org/10.1038/ncomms11472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858744PMC
May 2016

Development and Validation of a New HPLC Method for the Determination of Biphenyl and Dibenzofuran Phytoalexins in Rosaceae.

J Chromatogr Sci 2016 Jul 26;54(6):918-22. Epub 2016 Feb 26.

Plant Molecular Biology Group, Biotechnology Department, Indian Institute of Technology Roorkee, Roorkee 247 667, India

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http://dx.doi.org/10.1093/chromsci/bmw019DOI Listing
July 2016

Survey of pyrrolizidine alkaloids in seven varieties of Lappula squarrosa: An alternative source of heart-healthy vegetable oil.

Phytochem Anal 2016 Mar-Apr;27(2):133-9

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstrasse 1, 38106, Braunschweig, Germany.

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http://dx.doi.org/10.1002/pca.2608DOI Listing
October 2016

Hyperforin production in Hypericum perforatum root cultures.

J Biotechnol 2016 Mar 10;222:47-55. Epub 2016 Feb 10.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Braunschweig, Germany; Center of Pharmaceutical Engineering, Technische Universität Braunschweig, Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2016.02.016DOI Listing
March 2016

Molecular Cloning and Characterization of a Xanthone Prenyltransferase from Hypericum calycinum Cell Cultures.

Molecules 2015 Aug 27;20(9):15616-30. Epub 2015 Aug 27.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstraße 1, Braunschweig 38106, Germany.

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http://dx.doi.org/10.3390/molecules200915616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332024PMC
August 2015

Single cell subtractive transcriptomics for identification of cell-specifically expressed candidate genes of pyrrolizidine alkaloid biosynthesis.

Phytochemistry 2015 Sep 5;117:17-24. Epub 2015 Jun 5.

Botanical Institute and Botanical Garden, Christian-Albrechts University Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2015.05.003DOI Listing
September 2015

O-Methyltransferases involved in biphenyl and dibenzofuran biosynthesis.

Plant J 2015 Jul 25;83(2):263-76. Epub 2015 Jun 25.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr 1, 38106, Braunschweig, Germany.

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http://dx.doi.org/10.1111/tpj.12885DOI Listing
July 2015

Pyrrolizidine alkaloids in herbal teas for infants, pregnant or lactating women.

Food Chem 2015 Nov 22;187:491-8. Epub 2015 Apr 22.

Technische Universität Braunschweig, Institut für Pharmazeutische Biologie, Mendelssohnstr. 1, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2015.04.067DOI Listing
November 2015

Shoot cultures of Hoppea fastigiata (Griseb.) C.B. Clarke as potential source of neuroprotective xanthones.

J Nat Med 2015 Jul 22;69(3):375-86. Epub 2015 Apr 22.

Natural Product Biotechnology Group, Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, Kharagpur, 721 302, India.

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http://link.springer.com/10.1007/s11418-015-0904-x
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http://dx.doi.org/10.1007/s11418-015-0904-xDOI Listing
July 2015

Biphenyl 4-Hydroxylases Involved in Aucuparin Biosynthesis in Rowan and Apple Are Cytochrome P450 736A Proteins.

Plant Physiol 2015 Jun 10;168(2):428-42. Epub 2015 Apr 10.

Institute of Pharmaceutical Biology (D.S., M.M.G., D.R., T.B., B.L., L.B.) and Institute of Plant Biology (D.K., R.H.), Technische Universität Braunschweig, 38106 Braunschweig, Germany;Plant Pathology, Institute of Integrative Biology, Eidgenössische Technische Hochschule Zürich, 8092 Zurich, Switzerland (C.C., G.A.L.B.); andJulius Kühn-Institute, Federal Research Centre for Cultivated Plants, Institute for Breeding Research on Horticultural and Fruit Crops, 01326 Dresden, Germany (H.F.)

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http://dx.doi.org/10.1104/pp.15.00074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453778PMC
June 2015

Structural and quantitative analysis of Equisetum alkaloids.

Phytochemistry 2015 Aug 27;116:269-282. Epub 2015 Mar 27.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2015.03.003DOI Listing
August 2015

Pyrrolizidine alkaloids in the food chain: development, validation, and application of a new HPLC-ESI-MS/MS sum parameter method.

J Agric Food Chem 2013 Nov 19;61(47):11382-91. Epub 2013 Nov 19.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig , Mendelssohnstr. 1, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1021/jf403647uDOI Listing
November 2013

Biosynthesis of the biphenyl phytoalexin aucuparin in Sorbus aucuparia cell cultures treated with Venturia inaequalis.

Phytochemistry 2013 Dec 24;96:101-9. Epub 2013 Sep 24.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2013.09.003DOI Listing
December 2013

Crematoenones - a novel substance class exhibited by ants functions as appeasement signal.

Front Zool 2013 Jun 6;10(1):32. Epub 2013 Jun 6.

Department of Evolutionary Biology, University of Mainz, Institute of Zoology, Johannes-von-Müller-Weg 6, 55099, Mainz, Germany.

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http://dx.doi.org/10.1186/1742-9994-10-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691653PMC
June 2013

Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: a snapshot of the German situation in the autumn of 2012.

Drug Test Anal 2014 Jan-Feb;6(1-2):59-71. Epub 2013 May 30.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106, Braunschweig, Germany.

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http://dx.doi.org/10.1002/dta.1499DOI Listing
September 2014

In vitro formation of the anthranoid scaffold by cell-free extracts from yeast-extract-treated Cassia bicapsularis cell cultures.

Phytochemistry 2013 Apr 8;88:15-24. Epub 2013 Feb 8.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstrasse 1, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2013.01.001DOI Listing
April 2013

Detection and quantification of pyrrolizidine alkaloids in antibacterial medical honeys.

Planta Med 2012 Dec 16;78(18):1976-82. Epub 2012 Nov 16.

Department of Pharmaceutical Biology, Technical University of Braunschweig, Germany.

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http://dx.doi.org/10.1055/s-0032-1327900DOI Listing
December 2012

Synthetic cannabinoids in "spice-like" herbal blends: first appearance of JWH-307 and recurrence of JWH-018 on the German market.

Forensic Sci Int 2012 Oct 28;222(1-3):216-22. Epub 2012 Jun 28.

Chemistry Department, Central NMR Laboratory, Technische Universität Braunschweig, Hagenring 30, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.forsciint.2012.05.027DOI Listing
October 2012

Analysis of synthetic cannabinoids in "spice-like" herbal highs: snapshot of the German market in summer 2011.

Anal Bioanal Chem 2012 Jul 19;404(1):157-71. Epub 2012 Jun 19.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Braunschweig, Germany.

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http://link.springer.com/content/pdf/10.1007/s00216-012-6122
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http://link.springer.com/10.1007/s00216-012-6122-4
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http://dx.doi.org/10.1007/s00216-012-6122-4DOI Listing
July 2012

Independent recruitment of a flavin-dependent monooxygenase for safe accumulation of sequestered pyrrolizidine alkaloids in grasshoppers and moths.

PLoS One 2012 20;7(2):e31796. Epub 2012 Feb 20.

Biochemical Ecology and Molecular Evolution, Botanical Institute and Botanical Garden, Christian-Albrechts-Universität, Kiel, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031796PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282741PMC
June 2012

Identification and characterization of JWH-122 used as new ingredient in "Spice-like" herbal incenses.

Forensic Sci Int 2011 May 8;208(1-3):e31-5. Epub 2011 Apr 8.

Chemistry Department, Central NMR Laboratory, Technische Universität Braunschweig, Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.forsciint.2011.03.020DOI Listing
May 2011

4-Coumarate:CoA ligase family members from elicitor-treated Sorbus aucuparia cell cultures.

J Plant Physiol 2011 Jun 18;168(9):944-51. Epub 2011 Feb 18.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstraße 1, D-38106 Braunschweig, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01761617110002
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http://dx.doi.org/10.1016/j.jplph.2010.11.021DOI Listing
June 2011

Cinnamyl alcohols and methyl esters of fatty acids from Wedelia prostrata callus cultures.

Nat Prod Res 2011 Jan;25(1):45-52

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.

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http://www.tandfonline.com/doi/abs/10.1080/14786419.2010.482
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http://dx.doi.org/10.1080/14786419.2010.482937DOI Listing
January 2011

Differential effect of elicitors on biphenyl and dibenzofuran formation in Sorbus aucuparia cell cultures.

J Agric Food Chem 2010 Nov 20;58(22):11977-84. Epub 2010 Oct 20.

Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstrasse 1, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1021/jf1026857DOI Listing
November 2010

Pyrrolizidine alkaloids (PAs) in honey and pollen-legal regulation of PA levels in food and animal feed required.

Mol Nutr Food Res 2010 Jan;54(1):158-68

Lehrstuhl für Lebensmittelchemie, Universität Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/mnfr.200900529DOI Listing
January 2010

Pyrrolizidine alkaloids in pollen and pollen products.

Mol Nutr Food Res 2010 Feb;54(2):292-300

Lehrstuhl für Lebensmittelchemie, Universität Würzburg, Am Hubland, Würzburg, Germany.

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http://dx.doi.org/10.1002/mnfr.200900289DOI Listing
February 2010

A novel 4-hydroxycoumarin biosynthetic pathway.

Plant Mol Biol 2010 Jan 15;72(1-2):17-25. Epub 2009 Sep 15.

Institut für Pharmazeutische Biologie, Mendelssohnstrasse 1, 38106, Braunschweig, Germany.

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http://link.springer.com/10.1007/s11103-009-9548-0
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http://dx.doi.org/10.1007/s11103-009-9548-0DOI Listing
January 2010

A single amino acid substitution converts benzophenone synthase into phenylpyrone synthase.

J Biol Chem 2009 Nov 26;284(45):30957-64. Epub 2009 Aug 26.

Institute of Pharmaceutical Biology, Technical University of Braunschweig, Mendelssohnstrasse 1, D-38106 Braunschweig, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.038927
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http://dx.doi.org/10.1074/jbc.M109.038927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781496PMC
November 2009

Spice: a never ending story?

Forensic Sci Int 2009 Oct 8;191(1-3):58-63. Epub 2009 Jul 8.

Institute of Pharmaceutical Biology, Braunschweig University of Technology, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.forsciint.2009.06.008DOI Listing
October 2009

Homospermidine in transgenic tobacco results in considerably reduced spermidine levels but is not converted to pyrrolizidine alkaloid precursors.

Plant Mol Biol 2009 Sep 21;71(1-2):145-55. Epub 2009 Jun 21.

Botanisches Institut und Botanischer Garten, Universität Kiel, Olshausenstrasse 40, Kiel, Germany.

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http://dx.doi.org/10.1007/s11103-009-9514-xDOI Listing
September 2009

Benzaldehyde dehydrogenase from chitosan-treated Sorbus aucuparia cell cultures.

J Plant Physiol 2009 Sep 1;166(13):1343-9. Epub 2009 May 1.

Institute of Pharmaceutical Biology, Technical University of Braunschweig, Mendelssohnstrasse 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.jplph.2009.03.003DOI Listing
September 2009

Pyrrolizidine alkaloids in honey: risk analysis by gas chromatography-mass spectrometry.

Mol Nutr Food Res 2008 Oct;52(10):1193-200

Lehrstuhl für Lebensmittelchemie, Universität Würzburg, Würzburg, Germany.

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http://doi.wiley.com/10.1002/mnfr.200800051
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http://dx.doi.org/10.1002/mnfr.200800051DOI Listing
October 2008

Pyrrolizidine alkaloids of the endemic Mexican genus Pittocaulon and assignment of stereoisomeric 1,2-saturated necine bases.

Phytochemistry 2008 Jan 23;69(1):154-67. Epub 2007 Aug 23.

Laboratorio de Fitoquímica, UBIPRO, FES Iztacala, Universidad Nacional Autónoma de México, Av. De Los Barrios 1, Tlalnepantla 54090, Estado de México, Mexico.

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http://dx.doi.org/10.1016/j.phytochem.2007.07.004DOI Listing
January 2008

Absolute configuration of the creatonotines and callimorphines, two classes of arctiid-specific pyrrolizidine alkaloids.

Insect Biochem Mol Biol 2007 Jan 3;37(1):80-9. Epub 2006 Nov 3.

Institut für Pharmazeutische Biologie, Technische Universität, Mendelssohnstr. 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.ibmb.2006.10.005DOI Listing
January 2007

Biosynthesis of the hyperforin skeleton in Hypericum calycinum cell cultures.

Phytochemistry 2005 Jan;66(2):139-45

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstrasse 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2004.11.003DOI Listing
January 2005

The first prenylation step in hyperforin biosynthesis.

Phytochemistry 2005 Jan;66(1):51-7

Institut fuer Pharmazeutische Biologie, Technische Universitaet Braunschweig, Mendelssohnstr. 1, D-38106 Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.phytochem.2004.10.020DOI Listing
January 2005

Direct evidence for membrane transport of host-plant-derived pyrrolizidine alkaloid N-oxides in two leaf beetle genera.

J Chem Ecol 2004 Oct;30(10):2003-22

Biozentrum Grindel und Zoologisches Museum, Universität Hamburg, Martin-Luther-King-Platz 3, 20146 Hamburg, Germany.

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http://dx.doi.org/10.1023/b:joec.0000045591.26364.72DOI Listing
October 2004

Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia.

Planta 2004 Jan 1;218(3):492-6. Epub 2003 Nov 1.

Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstrasse 1, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.1007/s00425-003-1144-yDOI Listing
January 2004

O-methyltransferases involved in the biosynthesis of volatile phenolic derivatives in rose petals.

Plant Physiol 2002 Aug;129(4):1899-907

Vegetable Crops, Newe Ya'ar Research Center, Agricultural Research Organization, P.O. Box 1021, Ramat Yishay, 30095, Israel.

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http://dx.doi.org/10.1104/pp.005330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166779PMC
August 2002

Purification and characterization of benzoate:coenzyme A ligase from Clarkia breweri.

Arch Biochem Biophys 2002 Apr;400(2):258-64

Department of Molecular, Cellular and Developmental Biology, University of Michigan, 830 N. University Street, Ann Arbor, MI 48109-1048, USA.

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http://dx.doi.org/10.1016/S0003-9861(02)00026-7DOI Listing
April 2002

Enzymatic synthesis and purification of aromatic coenzyme a esters.

Anal Biochem 2002 Mar;302(2):305-12

Department of Molecular, Cellular and Developmental Biology, University of Michigan, 830 North University Street, Ann Arbor, Michigan 48109-1048, USA.

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http://dx.doi.org/10.1006/abio.2001.5574DOI Listing
March 2002