Tie-Lin Yang

Tie-Lin Yang

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Tie-Lin Yang

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An allele-specific functional SNP associated with two systemic autoimmune diseases modulates IRF5 expression by long-range chromatin loop formation.

J Invest Dermatol 2019 Aug 14. Epub 2019 Aug 14.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, P. R. China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.06.147DOI Listing
August 2019

Addressing the Missing Heritability Problem With the Help of Regulatory Features.

Evol Bioinform Online 2019 3;15:1176934319860861. Epub 2019 Jul 3.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P. R. China.

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http://dx.doi.org/10.1177/1176934319860861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610400PMC
July 2019

PopLDdecay: a fast and effective tool for linkage disequilibrium decay analysis based on variant call format files.

Bioinformatics 2019 May;35(10):1786-1788

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/bty875DOI Listing
May 2019

Detecting epistasis within chromatin regulatory circuitry reveals CAND2 as a novel susceptibility gene for obesity.

Int J Obes (Lond) 2019 03 1;43(3):450-456. Epub 2018 May 1.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, People's Republic of China.

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http://dx.doi.org/10.1038/s41366-018-0069-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298858PMC
March 2019

Integrating regulatory features data for prediction of functional disease-associated SNPs.

Brief Bioinform 2019 01;20(1):26-32

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University.

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http://academic.oup.com/bib/article/doi/10.1093/bib/bbx094/4
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http://dx.doi.org/10.1093/bib/bbx094DOI Listing
January 2019

Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia.

Transl Psychiatry 2019 01 31;9(1):56. Epub 2019 Jan 31.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, 710049, Xi'an, China.

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http://dx.doi.org/10.1038/s41398-019-0398-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355777PMC
January 2019

Runs of homozygosity associate with decreased risks of lung cancer in never-smoking East Asian females.

J Cancer 2018 5;9(21):3858-3866. Epub 2018 Oct 5.

Department of Joint Surgery, Honghui Hospital; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University, Xi'an, P. R. China.

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http://www.jcancer.org/v09p3858.htm
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http://dx.doi.org/10.7150/jca.22855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218761PMC
October 2018

Multiple Functional Variants at 13q14 Risk Locus for Osteoporosis Regulate RANKL Expression Through Long-Range Super-Enhancer.

J Bone Miner Res 2018 07 17;33(7):1335-1346. Epub 2018 May 17.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Shaanxi, Xi'an, People's Republic of China.

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http://doi.wiley.com/10.1002/jbmr.3419
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http://dx.doi.org/10.1002/jbmr.3419DOI Listing
July 2018

An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation.

Am J Hum Genet 2018 05 26;102(5):776-793. Epub 2018 Apr 26.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P. R. China. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986728PMC
May 2018

Regulatory element-based prediction identifies new susceptibility regulatory variants for osteoporosis.

Hum Genet 2017 08 20;136(8):963-974. Epub 2017 Jun 20.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, People's Republic of China.

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http://dx.doi.org/10.1007/s00439-017-1825-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550554PMC
August 2017

A functional SNP regulated by miR-196a-3p in the 3'UTR of FGF2 is associated with bone mineral density in the Chinese population.

Hum Mutat 2017 06 13;38(6):725-735. Epub 2017 Apr 13.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.1002/humu.23216DOI Listing
June 2017

SNP-SNP interactions between WNT4 and WNT5A were associated with obesity related traits in Han Chinese Population.

Sci Rep 2017 03 8;7:43939. Epub 2017 Mar 8.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P. R. China.

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http://dx.doi.org/10.1038/srep43939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341019PMC
March 2017

Epigenomic data facilitate genetic studies for osteoporosis in post-GWAS era.

Ann Transl Med 2017 Feb;5(4):93

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.

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http://dx.doi.org/10.21037/atm.2017.02.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337227PMC
February 2017

Replication of Caucasian Loci Associated with Osteoporosis-related Traits in East Asians.

J Bone Metab 2016 Nov 30;23(4):233-242. Epub 2016 Nov 30.

Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.11005/jbm.2016.23.4.233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153380PMC
November 2016

Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk.

Sci Rep 2016 07 28;6:30558. Epub 2016 Jul 28.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P. R. China.

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http://dx.doi.org/10.1038/srep30558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964617PMC
July 2016

Associations of Plasma FGF2 Levels and Polymorphisms in the FGF2 Gene with Obesity Phenotypes in Han Chinese Population.

Sci Rep 2016 Feb 16;6:19868. Epub 2016 Feb 16.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P. R. China.

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http://dx.doi.org/10.1038/srep19868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754629PMC
February 2016

Genome-wide association study identified copy number variants important for appendicular lean mass.

PLoS One 2014 13;9(3):e89776. Epub 2014 Mar 13.

Center of System Biomedical Sciences, University of Shanghai for Science and Technology, Shanghai, People's Republic of China; Department of Biostatistics and Bioinformatics, Tulane University, New Orleans, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953533PMC
January 2016

Genome-wide Survey of Runs of Homozygosity Identifies Recessive Loci for Bone Mineral Density in Caucasian and Chinese Populations.

J Bone Miner Res 2015 Nov 16;30(11):2119-26. Epub 2015 Jun 16.

School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.

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http://dx.doi.org/10.1002/jbmr.2558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615523PMC
November 2015

Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies.

Hum Mol Genet 2015 Aug 4;24(16):4710-27. Epub 2015 May 4.

Center for Bioinformatics and Genomics, Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA, Key Laboratory of Protein Chemistry and Developmental Biology of State Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, P. R. China,

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https://hmg.oxfordjournals.org/content/early/2015/06/11/hmg.
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512621PMC
August 2015

Association analyses of FGFR2 gene polymorphisms with femoral neck bone mineral density in Chinese Han population.

Mol Genet Genomics 2015 Apr 10;290(2):485-91. Epub 2014 Oct 10.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, People's Republic of China.

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http://dx.doi.org/10.1007/s00438-014-0936-zDOI Listing
April 2015

Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche.

PLoS One 2013 4;8(4):e60362. Epub 2013 Apr 4.

Center of System Biomedical Sciences, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, PR China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060362PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617200PMC
November 2013

Gene-gene interaction between RBMS3 and ZNF516 influences bone mineral density.

J Bone Miner Res 2013 Apr;28(4):828-37

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, PR China.

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http://dx.doi.org/10.1002/jbmr.1788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127986PMC
April 2013

Genome-wide association study identified CNP12587 region underlying height variation in Chinese females.

PLoS One 2012 5;7(9):e44292. Epub 2012 Sep 5.

Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, College of Medicine, Xi'an Jiaotong University, Xi'an, PR China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044292PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434125PMC
February 2013

Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study.

Hum Genet 2013 Feb 30;132(2):189-99. Epub 2012 Oct 30.

School of Basic Medical Science, Institute of Bioinformatics, Southern Medical University, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1007/s00439-012-1236-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682481PMC
February 2013

Copy number variation on chromosome 10q26.3 for obesity identified by a genome-wide study.

J Clin Endocrinol Metab 2013 Jan 21;98(1):E191-5. Epub 2012 Nov 21.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1210/jc.2012-2751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537105PMC
January 2013

The fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypes.

PLoS One 2011 18;6(11):e27312. Epub 2011 Nov 18.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027312PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220685PMC
April 2012

Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese.

Hum Genet 2012 Mar 25;131(3):463-9. Epub 2011 Sep 25.

Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, People's Republic of China.

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http://dx.doi.org/10.1007/s00439-011-1093-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450081PMC
March 2012

Genetic association study of common mitochondrial variants on body fat mass.

PLoS One 2011 29;6(6):e21595. Epub 2011 Jun 29.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021595PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126834PMC
November 2011

Copy number variation in CNP267 region may be associated with hip bone size.

PLoS One 2011 15;6(7):e22035. Epub 2011 Jul 15.

Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, Hunan, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022035PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137628PMC
November 2011

Mitochondria-wide association study of common variants in osteoporosis.

Ann Hum Genet 2011 Sep 18;75(5):569-74. Epub 2011 Jul 18.

Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, PR China.

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http://dx.doi.org/10.1111/j.1469-1809.2011.00663.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155639PMC
September 2011

Copy number variations at the Prader-Willi syndrome region on chromosome 15 and associations with obesity in whites.

Obesity (Silver Spring) 2011 Jun 13;19(6):1229-34. Epub 2011 Jan 13.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, The People's Republic of China.

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http://dx.doi.org/10.1038/oby.2010.323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512297PMC
June 2011

Molecular genetic studies of gene identification for osteoporosis: the 2009 update.

Endocr Rev 2010 Aug 31;31(4):447-505. Epub 2010 Mar 31.

Institute of Molecular Genetics, Xi'an Jiaotong University, Shaanxi, People's Republic of China.

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http://dx.doi.org/10.1210/er.2009-0032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365849PMC
August 2010

Runs of homozygosity identify a recessive locus 12q21.31 for human adult height.

J Clin Endocrinol Metab 2010 Aug 13;95(8):3777-82. Epub 2010 May 13.

Key Laboratory of Biomedical Information Engineering, Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1210/jc.2009-1715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913044PMC
August 2010

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults.

J Hum Genet 2010 Jul 7;55(7):441-7. Epub 2010 May 7.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1038/jhg.2010.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923432PMC
July 2010

IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study.

J Bone Miner Res 2010 May;25(5):1042-8

Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.1359/jbmr.091040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153368PMC
May 2010

Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function.

Immunogenetics 2010 Apr 9;62(4):237-51. Epub 2010 Mar 9.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, People's Republic of China.

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http://dx.doi.org/10.1007/s00251-010-0431-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925024PMC
April 2010

HMGA2 is confirmed to be associated with human adult height.

Ann Hum Genet 2010 Jan 20;74(1):11-6. Epub 2009 Nov 20.

Institute of Molecular Genetics, Xi'an Jiaotong University, P. R. China.

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http://dx.doi.org/10.1111/j.1469-1809.2009.00555.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972475PMC
January 2010

Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population.

J Hum Genet 2009 Apr 20;54(4):199-202. Epub 2009 Feb 20.

Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, Hunan, PR China.

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http://dx.doi.org/10.1038/jhg.2009.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733232PMC
April 2009

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.

Am J Hum Genet 2009 Mar 5;84(3):418-23. Epub 2009 Mar 5.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an Shaanxi, P R China.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970900066
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http://dx.doi.org/10.1016/j.ajhg.2009.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668008PMC
March 2009

Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.

Hum Genet 2009 Feb 23;125(1):1-9. Epub 2008 Nov 23.

Laboratory of Molecular and Statistical Genetics and Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, 410081 Changsha, Hunan, People's Republic of China.

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http://dx.doi.org/10.1007/s00439-008-0590-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730511PMC
February 2009

Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis.

Am J Hum Genet 2008 Dec 6;83(6):663-74. Epub 2008 Nov 6.

Key Laboratory of Biomedical Information Engineering of the Ministry of Education, Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.1016/j.ajhg.2008.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667994PMC
December 2008

Comprehensive association analyses of IGF1, ESR2, and CYP17 genes with adult height in Caucasians.

Eur J Hum Genet 2008 Nov 18;16(11):1380-7. Epub 2008 Jun 18.

The Key Laboratory of Biomedical Information Engineering, Ministry of Education, Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, PR China.

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http://dx.doi.org/10.1038/ejhg.2008.113DOI Listing
November 2008

Polymorphisms in the estrogen receptor genes are associated with hip fractures in Chinese.

Bone 2008 Nov 15;43(5):910-4. Epub 2008 Jul 15.

Department of Orthopaedics, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710061, PR China.

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http://dx.doi.org/10.1016/j.bone.2008.07.001DOI Listing
November 2008

Quantitative trait loci mapping.

Methods Mol Biol 2008 ;455:203-35

Osteoporosis Research Center, Creighton University, Omaha, NE, USA.

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http://dx.doi.org/10.1007/978-1-59745-104-8_16DOI Listing
June 2008

Bivariate genome linkage analysis suggests pleiotropic effects on chromosomes 20p and 3p for body fat mass and lean mass.

Genet Res (Camb) 2008 Jun;90(3):259-68

Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1017/S0016672308009257DOI Listing
June 2008

Molecular genetic studies of gene identification for osteoporosis.

Expert Rev Endocrinol Metab 2008 Mar;3(2):223-267

b The Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, PR China and Departments of Orthopedic Surgery and Basic Medical Sciences, University of Missouri - Kansas City, Kansas City, MO 64108, USA.

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http://dx.doi.org/10.1586/17446651.3.2.223DOI Listing
March 2008

Variations in RANK gene are associated with adult height in Caucasians.

Am J Hum Biol 2007 Jul-Aug;19(4):559-65

Laboratory of Molecular and Statistical Genetics, College of Life Science, Hunan Normal University, Changsha, Hunan 410081, People's Republic of China.

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http://dx.doi.org/10.1002/ajhb.20619DOI Listing
August 2007

Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females.

Hum Reprod 2007 Jun 21;22(6):1789-94. Epub 2007 Mar 21.

The Key Laboratory of Biomedical Information Engineering, Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1093/humrep/dem052DOI Listing
June 2007

Epistatic interactions between genomic regions containing the COL1A1 gene and genes regulating osteoclast differentiation may influence femoral neck bone mineral density.

Ann Hum Genet 2007 Mar;71(Pt 2):152-9

The Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P R China.

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http://dx.doi.org/10.1111/j.1469-1809.2006.00313.xDOI Listing
March 2007

Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.

J Med Genet 2006 Oct 24;43(10):798-803. Epub 2006 May 24.

Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, PR China.

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http://dx.doi.org/10.1136/jmg.2006.041715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829485PMC
October 2006

Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families.

Hum Genet 2006 Aug 30;120(1):119-25. Epub 2006 May 30.

The Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1007/s00439-006-0199-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829483PMC
August 2006

Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females.

Hum Mol Genet 2006 Aug 16;15(16):2401-8. Epub 2006 Jun 16.

Key Laboratory of Biomedical Information Engineering, Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1093/hmg/ddl155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803760PMC
August 2006

Genomewide linkage scan for quantitative trait loci underlying variation in age at menarche.

J Clin Endocrinol Metab 2006 Mar 4;91(3):1009-14. Epub 2006 Jan 4.

Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Molecular Genetics, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.

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http://dx.doi.org/10.1210/jc.2005-2179DOI Listing
March 2006