Tibor Kristian

Tibor Kristian

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Tibor Kristian

Tibor Kristian

Publications by authors named "Tibor Kristian"

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Multi-targeted Effect of Nicotinamide Mononucleotide on Brain Bioenergetic Metabolism.

Neurochem Res 2019 Oct 19;44(10):2280-2287. Epub 2019 Jan 19.

Veterans Affairs Maryland Health Care System, 10 North Greene Street, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1007/s11064-019-02729-0DOI Listing
October 2019

Interplay between NAD and acetyl‑CoA metabolism in ischemia-induced mitochondrial pathophysiology.

Biochim Biophys Acta Mol Basis Dis 2019 Aug 24;1865(8):2060-2067. Epub 2018 Sep 24.

Veterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD 21201, USA; Department of Anesthesiology, Center for Shock, Trauma, and Anesthesiology Research (S.T.A.R.), USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.09.025DOI Listing
August 2019

Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice.

J Neurosci Res 2019 Aug 23;97(8):975-990. Epub 2019 Feb 23.

Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/jnr.24397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565489PMC
August 2019

Genetic inhibition of PKCε attenuates neurodegeneration after global cerebral ischemia in male mice.

J Neurosci Res 2019 Apr 29;97(4):444-455. Epub 2018 Nov 29.

Department of Biological Sciences, School of Biomedical Sciences, Kent State University, Kent, Ohio.

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http://dx.doi.org/10.1002/jnr.24362DOI Listing
April 2019

Significance of Mitochondrial Protein Post-translational Modifications in Pathophysiology of Brain Injury.

Transl Stroke Res 2018 06 21;9(3):223-237. Epub 2017 Sep 21.

Veterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1007/s12975-017-0569-8DOI Listing
June 2018

The Protein Modification and Degradation Pathways after Brain Ischemia.

Transl Stroke Res 2018 06 1;9(3):199-200. Epub 2017 Oct 1.

Department of Anesthesiology, Shock Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

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http://link.springer.com/10.1007/s12975-017-0573-z
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http://dx.doi.org/10.1007/s12975-017-0573-zDOI Listing
June 2018

Mitochondrial NUDIX hydrolases: A metabolic link between NAD catabolism, GTP and mitochondrial dynamics.

Neurochem Int 2017 Oct 14;109:193-201. Epub 2017 Mar 14.

Veterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD 21201, United States; Department of Anesthesiology and the Center for Shock, Trauma, and Anesthesiology Research (S.T.A.R.), United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01970186173005
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http://dx.doi.org/10.1016/j.neuint.2017.03.009DOI Listing
October 2017

CD38 Knockout Mice Show Significant Protection Against Ischemic Brain Damage Despite High Level Poly-ADP-Ribosylation.

Neurochem Res 2017 Jan 12;42(1):283-293. Epub 2016 Aug 12.

Veterans Affairs Maryland Health Care System, 10 North Greene Street, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1007/s11064-016-2031-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580240PMC
January 2017

Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.

Neurobiol Dis 2016 Nov 15;95:102-10. Epub 2016 Jul 15.

Veterans Affairs Maryland Health Care System, 10 North Greene Street, Baltimore, MD 21201, USA; Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research, School of Medicine, University of Maryland, Baltimore, 685 West Baltimore Street, MSTF 534, Baltimore, MD 21201, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961163017
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http://dx.doi.org/10.1016/j.nbd.2016.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580241PMC
November 2016

Mitochondrial dynamics: cell-type and hippocampal region specific changes following global cerebral ischemia.

J Bioenerg Biomembr 2015 Apr 24;47(1-2):13-31. Epub 2014 Sep 24.

Veterans Affairs Maryland Health Care System, 10 North Greene Street, Baltimore, MD, 21201, USA.

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http://link.springer.com/10.1007/s10863-014-9575-7
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http://dx.doi.org/10.1007/s10863-014-9575-7DOI Listing
April 2015

Brain diabetic neurodegeneration segregates with low intrinsic aerobic capacity.

Ann Clin Transl Neurol 2014 Aug 19;1(8):589-604. Epub 2014 Aug 19.

Department of Neurology, University of Maryland Baltimore, Maryland, 21201 ; Veterans Affairs Medical Center Baltimore, Maryland, 21201.

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http://dx.doi.org/10.1002/acn3.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184561PMC
August 2014

Mitochondrial dysfunction and NAD(+) metabolism alterations in the pathophysiology of acute brain injury.

Transl Stroke Res 2013 Dec 10;4(6):618-34. Epub 2013 Aug 10.

Veterans Affairs Maryland Health Care System, 10 North Greene Street, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1007/s12975-013-0278-xDOI Listing
December 2013

Utilizing commercial microwave for rapid and effective immunostaining.

J Neurosci Methods 2013 Sep 12;219(1):20-6. Epub 2013 Jul 12.

Veterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD 21201, United States.

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http://dx.doi.org/10.1016/j.jneumeth.2013.07.002DOI Listing
September 2013

Guidelines for using mouse global cerebral ischemia models.

Transl Stroke Res 2013 Jun 14;4(3):343-50. Epub 2012 Dec 14.

Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research, School of Medicine, University of Maryland Baltimore, 685 West Baltimore street, MSTF 534, Baltimore, MD, 21201, USA,

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http://dx.doi.org/10.1007/s12975-012-0236-zDOI Listing
June 2013

Simple model of forebrain ischemia in mouse.

J Neurosci Methods 2012 Mar 28;204(2):254-61. Epub 2011 Nov 28.

Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research, School of Medicine, University of Maryland Baltimore, 685 West Baltimore street, MSTF 534, Baltimore, MD 21201, United States.

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http://dx.doi.org/10.1016/j.jneumeth.2011.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273657PMC
March 2012

Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection.

J Neurosci Res 2011 Dec 12;89(12):1946-55. Epub 2011 Apr 12.

Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research, School of Medicine, University of Maryland Baltimore, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1002/jnr.22626DOI Listing
December 2011

Isolation of mitochondria from the CNS.

Authors:
Tibor Kristian

Curr Protoc Neurosci 2010 Jul;Chapter 7:Unit 7.22

Department of Anesthesiology, Organized Research Center, School of Medicine, University of Maryland, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/0471142301.ns0722s52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908900PMC
July 2010

Visualization and quantification of NAD(H) in brain sections by a novel histo-enzymatic nitrotetrazolium blue staining technique.

Brain Res 2010 Feb 28;1316:112-9. Epub 2009 Dec 28.

Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research, University of Maryland, School of Medicine 685 W. Baltimore St., MSTF 5.34, Baltimore, MD 21201, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00068993090271
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http://dx.doi.org/10.1016/j.brainres.2009.12.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822014PMC
February 2010

Cyclophilin D is expressed predominantly in mitochondria of gamma-aminobutyric acidergic interneurons.

J Neurosci Res 2009 Apr;87(5):1250-9

Department of Anesthesiology Research, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1002/jnr.21921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650012PMC
April 2009

Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders.

J Neurosci Res 2007 Nov;85(15):3407-15

Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1002/jnr.21498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570316PMC
November 2007

Calcium-induced precipitate formation in brain mitochondria: composition, calcium capacity, and retention.

J Neurochem 2007 Aug;102(4):1346-56

Department of Anesthesiology, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04626.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566803PMC
August 2007

The IFN-beta and retinoic acid-induced cell death regulator GRIM-19 is upregulated during focal cerebral ischemia.

J Interferon Cytokine Res 2007 May;27(5):383-92

Department of Anesthesiology, University of Maryland School of Medicine, 685 W. Baltimore Street, Baltimore, MD 21201, USA.

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http://www.liebertpub.com/doi/10.1089/jir.2006.0067
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http://dx.doi.org/10.1089/jir.2006.0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597162PMC
May 2007

Neuron-specific conditional expression of a mitochondrially targeted fluorescent protein in mice.

J Neurosci 2006 Dec;26(51):13123-7

Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4191-06.2
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http://dx.doi.org/10.1523/JNEUROSCI.4191-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572759PMC
December 2006

Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity.

Free Radic Biol Med 2006 Jun 17;40(11):1960-70. Epub 2006 Feb 17.

Department of Anesthesiology, University of Maryland, Baltimore, MD 21201, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490600065
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http://dx.doi.org/10.1016/j.freeradbiomed.2006.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570699PMC
June 2006

Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation.

J Neurosci Methods 2006 Apr 25;152(1-2):136-43. Epub 2005 Oct 25.

Department of Anesthesiology, School of Medicine, University of Maryland, 685 West Baltimore Street, MSTF 534, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2005.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572758PMC
April 2006

Methoxychlor inhibits brain mitochondrial respiration and increases hydrogen peroxide production and CREB phosphorylation.

Toxicol Sci 2005 Dec 21;88(2):495-504. Epub 2005 Sep 21.

Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, 21201, USA.

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http://dx.doi.org/10.1093/toxsci/kfi334DOI Listing
December 2005

Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage.

Authors:
Tibor Kristián

Cell Calcium 2004 Sep-Oct;36(3-4):221-33

Anesthesiology Research Laboratories, Department of Anesthesiology, School of Medicine, University of Maryland, 685 W. Baltimore Street, MSTF 5-34, Baltimore, MD 21201, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S014341600400060
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http://dx.doi.org/10.1016/j.ceca.2004.02.016DOI Listing
January 2005

Calcium-dependent dephosphorylation of brain mitochondrial calcium/cAMP response element binding protein (CREB).

J Neurochem 2005 Jan;92(2):388-94

Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02873.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572760PMC
January 2005

A fluorescence-based technique for screening compounds that protect against damage to brain mitochondria.

Brain Res Brain Res Protoc 2004 Aug;13(3):176-82

Department of Anesthesiology, School of Medicine, University of Maryland, 685 West Baltimore Street, MSTF 5-34, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/j.brainresprot.2004.05.001DOI Listing
August 2004

Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection.

Neurochem Res 2004 Mar;29(3):601-8

Department of Anesthesiology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1023/b:nere.0000014830.06376.e6DOI Listing
March 2004

Heterogeneity of the calcium-induced permeability transition in isolated non-synaptic brain mitochondria.

J Neurochem 2002 Dec;83(6):1297-308

Department of Anesthesiology, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1046/j.1471-4159.2002.01238.xDOI Listing
December 2002

Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition.

Neurobiol Dis 2002 Aug;10(3):219-33

Department of Molecular Cell Physiology, Tokyo Metropolitan Institute of Medical Science, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo, 113-8613, Japan

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August 2002

Effect of NXY-059 on secondary mitochondrial dysfunction after transient focal ischemia; comparison with cyclosporin A.

Brain Res 2002 Apr;932(1-2):99-109

Center for the Study of Neurological Disease, Neuroscience Institute, Queen's Medical Center, Honolulu, HI, USA.

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http://dx.doi.org/10.1016/s0006-8993(02)02286-2DOI Listing
April 2002