Tibor Keler

Tibor Keler

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Tibor Keler

Tibor Keler

Publications by authors named "Tibor Keler"

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57Publications

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Conventional Dendritic Cells Impair Recovery after Myocardial Infarction.

J Immunol 2018 09 10;201(6):1784-1798. Epub 2018 Aug 10.

Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec H3T 1J4, Canada.

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http://dx.doi.org/10.4049/jimmunol.1800322DOI Listing
September 2018

Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.

Cancer Cell 2017 Dec 30;32(6):777-791.e6. Epub 2017 Nov 30.

Antibody and Vaccine Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK; Cancer Research UK Centre, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734932PMC
December 2017

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.

Immunity 2017 12 5;47(6):1037-1050.e6. Epub 2017 Dec 5.

Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA; Program in Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738280PMC
December 2017

M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1.

Cell Rep 2017 Oct;21(1):126-140

Center for Microbial Interface Biology, The Ohio State University, Columbus, OH 43210, USA; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173130
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http://dx.doi.org/10.1016/j.celrep.2017.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960073PMC
October 2017

Safety and Activity of Varlilumab, a Novel and First-in-Class Agonist Anti-CD27 Antibody, in Patients With Advanced Solid Tumors.

J Clin Oncol 2017 Jun 2;35(18):2028-2036. Epub 2017 May 2.

Howard A. Burris and Jeffrey R. Infante, Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN; Stephen M. Ansell, Mayo Clinic, Rochester, MN; John J. Nemunaitis, Mary Crowley Cancer Research Center, Dallas, TX; Geoffrey R. Weiss and Timothy Bullock, University of Virginia, Charlottesville, VA; Victor M. Villalobos and Branimir I. Sikic, Stanford Cancer Institute, Stanford, CA; Matthew H. Taylor, Oregon Health & Science University, Portland, OR; Donald W. Northfelt, Mayo Clinic, Scottsdale, AZ; William E. Carson III, The Ohio State University, Columbus, OH; Thomas R. Hawthorne, Thomas A. Davis, Michael J. Yellin, and Tibor Keler, Celldex Therapeutics, Hampton, NJ.

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http://ascopubs.org/doi/10.1200/JCO.2016.70.1508
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http://dx.doi.org/10.1200/JCO.2016.70.1508DOI Listing
June 2017

Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells.

Cell Metab 2016 05;23(5):852-66

Laboratory of Cellular Physiology and Immunology, Institut de Recherches Cliniques de Montréal, Montréal, QC H2W 1R7, Canada; Division of Experimental Medicine, Department of Medicine, McGill University, Montréal, QC H3A 1A3, Canada; Department of Microbiology, Infectiology, and Immunology, Université de Montréal, Montréal, QC H3C 3J7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.010DOI Listing
May 2016

Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine.

Cell Mol Immunol 2015 Nov 27;12(6):719-28. Epub 2014 Oct 27.

Celldex Therapeutics, Inc., Hampton, NJ, USA.

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http://dx.doi.org/10.1038/cmi.2014.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716615PMC
November 2015

A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.

Neuro Oncol 2015 Jun 13;17(6):854-61. Epub 2015 Jan 13.

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania (J.S.); The Neurological Institute of Columbia University, New York, New York (R.K.L.); Stanford Cancer Center, Stanford, California (L.D.R.); Duke University Medical Center, Durham, North Carolina (D.A.R., G.E.A., D.D.B., J.H.S.); Evanston Northwestern Healthcare, Evanston, Illinois (N.A.P.); University of Texas M.D. Anderson Cancer Center, Houston, Texas (M.D.G.); University of Washington School of Medicine, Seattle, Washington (M.M.M.); Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah (R.J.); Yale University School of Medicine, New Haven, Connecticut (J.M.B); University Hospital-Case Medical Center & Case Comprehensive Cancer Center, Cleveland, Ohio (A.S.); Scott Cruickshank & Associates, Inc., Santa Barbara, C alifornia (S.C.); Celldex Therapeutics, Inc., Hampton, New Jersey (J.A.G., T.K., T.A.D.); University of Texas M.D. Anderson Cancer Center, Houston, Texas (A.B.H.).

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http://dx.doi.org/10.1093/neuonc/nou348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483122PMC
June 2015

Circulating precursors of human CD1c+ and CD141+ dendritic cells.

J Exp Med 2015 Mar 16;212(3):401-13. Epub 2015 Feb 16.

Laboratory of Molecular Immunology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065 Laboratory of Molecular Immunology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065

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http://dx.doi.org/10.1084/jem.20141441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354370PMC
March 2015

Phase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with locally advanced or metastatic breast cancer.

J Clin Oncol 2014 Nov 29;32(32):3619-25. Epub 2014 Sep 29.

Johanna Bendell and Suzanne Jones, Sarah Cannon Research Institute, Nashville, TN; Mansoor Saleh, Georgia Cancer Specialists, Atlanta, GA; April A.N. Rose and Peter M. Siegel, Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada; Lowell Hart, Florida Cancer Specialists, Fort Myers; Surendra Sirpal, Hematology Oncology Associates, Lake Worth, FL; Jennifer Green, Elizabeth Crowley, Ronit Simantov, Tibor Keler, and Thomas Davis, Celldex Therapeutics; and Linda Vahdat, Weill Cornell Medical College, New York, NY.

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http://dx.doi.org/10.1200/JCO.2013.52.5683DOI Listing
November 2014

Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice.

Breast Cancer Res 2012 Mar 7;14(2):R39. Epub 2012 Mar 7.

Laboratory of Cellular Physiology and Immunology and Chris Browne Center of Immunology and Immune Disease, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA.

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http://dx.doi.org/10.1186/bcr3135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446373PMC
March 2012

CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer.

Expert Rev Vaccines 2011 Jun;10(6):733-42

Duke University Medical Center, 10 Bryan Searle Drive, 477 Seeley G. Mudd Building, Durham, NC 27710, USA.

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http://dx.doi.org/10.1586/erv.11.20DOI Listing
June 2011

Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity.

J Immunol 2011 Jan 13;186(2):1218-27. Epub 2010 Dec 13.

Ludwig Institute for Cancer Research, Ltd., New York Branch, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.4049/jimmunol.1000808DOI Listing
January 2011

Assessing vaccine potency using TCRmimic antibodies.

Vaccine 2008 Jun 25;26(25):3092-102. Epub 2008 Feb 25.

Receptor Logic Ltd., Abilene, TX 79601, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S0264410X0800154
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http://dx.doi.org/10.1016/j.vaccine.2008.02.025DOI Listing
June 2008

Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.

Br J Haematol 2006 Feb;132(3):317-25

Immunotherapy Laboratory, Department of Immunology, University Medical Centre Utrecht, Lundlaan, Utrecht, The Netherlands.

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http://doi.wiley.com/10.1111/j.1365-2141.2005.05884.x
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http://dx.doi.org/10.1111/j.1365-2141.2005.05884.xDOI Listing
February 2006

Tumor immunotherapy: preclinical and clinical activity of anti-CTLA4 antibodies.

Curr Opin Investig Drugs 2005 Jun;6(6):582-91

Medarex Inc, 521 Cottonwood Drive, Milpitas, CA 95035, USA.

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June 2005

Development of antibody-targeted vaccines.

Curr Opin Mol Ther 2005 Apr;7(2):157-63

Medarex Inc, 519 Route 173 West, Bloomsbury, NJ 08804, USA.

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April 2005

Mannose receptor-targeted vaccines.

Expert Opin Biol Ther 2004 Dec;4(12):1953-62

Medarex, Inc., 519 Route 173 West, Bloomsbury, NJ 08804, USA.

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http://www.tandfonline.com/doi/full/10.1517/14712598.4.12.19
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http://dx.doi.org/10.1517/14712598.4.12.1953 DOI Listing
December 2004

Flow cytometric determination of FcgammaRIIa (CD32) polymorphism.

J Immunol Methods 2004 Nov 6;294(1-2):135-44. Epub 2004 Oct 6.

Immunotherapy Laboratory, Department of Immunology, KC 02.085.2, University Medical Center Utrecht, Lundlaan 6, 35484 EA, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jim.2004.09.010DOI Listing
November 2004

Activity and safety of CTLA-4 blockade combined with vaccines in cynomolgus macaques.

J Immunol 2003 Dec;171(11):6251-9

Department of Preclinical Development, Medarex, Bloomsbury, NJ 08804, USA.

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http://dx.doi.org/10.4049/jimmunol.171.11.6251DOI Listing
December 2003

The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma.

Blood 2003 Nov 24;102(10):3737-42. Epub 2003 Jul 24.

Klinik I für Innere Medizin der Universität Köln, Joseph-Stelzmann Strasse 9, 50924 Cologne, Germany.

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http://dx.doi.org/10.1182/blood-2003-02-0515DOI Listing
November 2003