Publications by authors named "Tianzuo Zhan"

24Publications

Multi-omics integration identifies a selective vulnerability of colorectal cancer subtypes to YM155.

Int J Cancer 2020 Nov 13. Epub 2020 Nov 13.

Division of Signaling and Functional Genomics, German Cancer Research Center (DKFZ), Department of Cell and Molecular Biology, Faculty of Medicine Mannheim, Heidelberg University, Heidelberg, Germany.

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November 2020

Cancer-Associated Mutations in Normal Colorectal Mucosa Adjacent to Sporadic Neoplasia.

Clin Transl Gastroenterol 2020 Jul;11(7):e00212

1Department Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; 2German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics and Department of Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany; 3Central Interdisciplinary Endoscopy (ZIE), University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; 4Institute of Pathology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; 5German Cancer Consortium (DKTK), Heidelberg, Germany.

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July 2020

Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids.

Cell Stem Cell 2020 05 28;26(5):782-792.e7. Epub 2020 Apr 28.

German Cancer Consortium (DKTK), 69120 Heidelberg, Germany; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt am Main, Germany; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Frankfurt Cancer Institute, Goethe University, 60596 Frankfurt am Main, Germany. Electronic address:

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May 2020

Complete Remission of Metastatic HER2+ Oesophagogastric Junctional Adenocarcinoma under long-term Trastuzumab Treatment.

J Gastrointestin Liver Dis 2019 Dec 9;28(4):503-507. Epub 2019 Dec 9.

Department of Medicine II, University Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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December 2019

The effect of gender-specific invitation letters on utilization of colorectal cancer screening.

Z Gastroenterol 2019 Sep 16;57(9):1051-1058. Epub 2019 Sep 16.

Department of Internal Medicine II, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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September 2019

Management of immune related adverse events induced by immune checkpoint inhibition.

Cancer Lett 2019 08 30;456:80-87. Epub 2019 Apr 30.

Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Theodor Kutzer Ufer 1-3, 68167, Mannheim, Germany.

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August 2019

A multicenter open-label phase II trial to evaluate nivolumab and ipilimumab for 2nd line therapy in elderly patients with advanced esophageal squamous cell cancer (RAMONA).

BMC Cancer 2019 Mar 14;19(1):231. Epub 2019 Mar 14.

Department of Medicine II, University Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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March 2019

CRISPR/Cas9 for cancer research and therapy.

Semin Cancer Biol 2019 04 16;55:106-119. Epub 2018 Apr 16.

German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics, and Heidelberg University, Department Cell and Molecular Biology, Faculty of Medicine Mannheim, Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:

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April 2019

Invitation letters increase participation in colorectal cancer screening - results from an observational study.

Z Gastroenterol 2017 Dec 6;55(12):1307-1312. Epub 2017 Dec 6.

Department of Internal Medicine II, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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December 2017

Multiple behavioral factors are associated with occurrence of large, flat colorectal polyps.

Int J Colorectal Dis 2017 Apr 28;32(4):575-582. Epub 2016 Nov 28.

Department of Internal Medicine II, Medical Faculty Mannheim, Heidelberg University, Universitätsmedizin Mannheim, Theodor-Kutzer Ufer 1-3, D-68167, Mannheim, Germany.

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April 2017

Risk Factors for Local Recurrence of Large, Flat Colorectal Polyps after Endoscopic Mucosal Resection.

Digestion 2016 7;93(4):311-7. Epub 2016 Jun 7.

Divisions of Signaling and Functional Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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March 2017

CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries.

Genome Biol 2016 Mar 24;17:55. Epub 2016 Mar 24.

Division Signaling and Functional Genomics, German Cancer Research Center (DKFZ) and Heidelberg University, Im Neuenheimer Feld 580, Heidelberg, 69120, Germany.

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March 2016

Towards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells.

Crit Rev Biochem Mol Biol 2016 1;51(2):74-85. Epub 2015 Dec 1.

a Department of Cell and Molecular Biology , Division of Signaling and Functional Genomics, Medical Faculty Mannheim, German Cancer Research Center (DKFZ), Heidelberg University , Heidelberg , Germany and.

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November 2016

caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens.

Bioinformatics 2016 Feb 27;32(4):632-4. Epub 2015 Oct 27.

German Cancer Research Center (DKFZ), Division Signaling and Functional Genomics and Heidelberg University, Heidelberg, Germany and.

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February 2016

Frequent co-occurrence of high-grade dysplasia in large flat colonic polyps (>20 mm) and synchronous polyps.

BMC Gastroenterol 2015 Jul 10;15:82. Epub 2015 Jul 10.

Department of Internal Medicine II, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer Ufer 1-3, D-68167, Mannheim, Germany.

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July 2015