Publications by authors named "Tianxia Li"

22Publications

Synphilin-1 Interacts with AMPK and Increases AMPK Phosphorylation.

Int J Mol Sci 2020 Jun 18;21(12). Epub 2020 Jun 18.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.3390/ijms21124352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352261PMC
June 2020

GTP-binding inhibitors increase LRRK2-linked ubiquitination and Lewy body-like inclusions.

J Cell Physiol 2020 Oct 17;235(10):7309-7320. Epub 2020 Mar 17.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/jcp.29632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473462PMC
October 2020

The Drosophila hep pathway mediates Lrrk2-induced neurodegeneration.

Biochem Cell Biol 2018 08 21;96(4):441-449. Epub 2017 Dec 21.

a Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://www.nrcresearchpress.com/doi/10.1139/bcb-2017-0262
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http://dx.doi.org/10.1139/bcb-2017-0262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441734PMC
August 2018

68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment.

Front Aging Neurosci 2016 10;8:337. Epub 2017 Jan 10.

Department of Psychiatry, Johns Hopkins University School of Medicine Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fnagi.2016.00337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222795PMC
January 2017

Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models.

Hum Mol Genet 2016 Feb 6;25(4):672-80. Epub 2016 Jan 6.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD 21201, USA,

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http://hmg.oxfordjournals.org/content/early/2016/01/10/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743687PMC
February 2016

CCK Response Deficiency in Synphilin-1 Transgenic Mice.

PLoS One 2015 16;10(11):e0142314. Epub 2015 Nov 16.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142314PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646498PMC
June 2016

A novel GTP-binding inhibitor, FX2149, attenuates LRRK2 toxicity in Parkinson's disease models.

PLoS One 2015 27;10(3):e0122461. Epub 2015 Mar 27.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122461PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376719PMC
March 2016

Synphilin-1 binds ATP and regulates intracellular energy status.

PLoS One 2014 29;9(12):e115233. Epub 2014 Dec 29.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115233PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278857PMC
September 2015

Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models.

Hum Mol Genet 2014 Dec 3;23(23):6212-22. Epub 2014 Jul 3.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA

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http://dx.doi.org/10.1093/hmg/ddu341DOI Listing
December 2014

Behavioral characterization of the hyperphagia synphilin-1 overexpressing mice.

PLoS One 2014 14;9(5):e91449. Epub 2014 May 14.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091449PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020742PMC
December 2014

From fat fruit fly to human obesity.

Physiol Behav 2014 Sep 6;136:15-21. Epub 2014 Feb 6.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.physbeh.2014.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125553PMC
September 2014

Ellagic acid-induced thrombotic focal cerebral ischemic model in rats.

J Pharmacol Toxicol Methods 2014 May-Jun;69(3):217-22. Epub 2014 Jan 10.

Department of Pharmacology, Xi'an Jiaotong University School of Medicine, Xi'an, China. Electronic address:

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http://dx.doi.org/10.1016/j.vascn.2014.01.001DOI Listing
November 2014

LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin.

Neurobiol Dis 2012 Sep 2;47(3):385-92. Epub 2012 Jun 2.

Department of Physiology and Pathophysiology, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi, PR China.

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http://dx.doi.org/10.1016/j.nbd.2012.05.020DOI Listing
September 2012

Preproendothelin-1 expression is negatively regulated by IFNγ during hepatic stellate cell activation.

Am J Physiol Gastrointest Liver Physiol 2012 May 2;302(9):G948-57. Epub 2012 Feb 2.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8887, USA.

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http://dx.doi.org/10.1152/ajpgi.00359.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362071PMC
May 2012

Models for LRRK2-Linked Parkinsonism.

Parkinsons Dis 2011 7;2011:942412. Epub 2011 Apr 7.

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.4061/2011/942412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096154PMC
July 2011

Protective effect of protopine on the focal cerebral ischaemic injury in rats.

Basic Clin Pharmacol Toxicol 2007 Aug;101(2):85-9

Department of Pharmacology, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1111/j.1742-7843.2007.00075.xDOI Listing
August 2007