Tian-yan Zhou

Tian-yan Zhou

UNVERIFIED PROFILE

Are you Tian-yan Zhou?   Register this Author

Register author
Tian-yan Zhou

Tian-yan Zhou

Publications by authors named "Tian-yan Zhou"

Are you Tian-yan Zhou?   Register this Author

39Publications

620Reads

31Profile Views

Dexamethasone inhibits pancreatic tumor growth in preclinical models: Involvement of activating glucocorticoid receptor.

Toxicol Appl Pharmacol 2020 Jul 1;401:115118. Epub 2020 Jul 1.

Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2020.115118DOI Listing
July 2020

Disease progression model of 4T1 metastatic breast cancer.

J Pharmacokinet Pharmacodyn 2020 Feb 22;47(1):105-116. Epub 2020 Jan 22.

Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10928-020-09673-5DOI Listing
February 2020

Preclinical PK/PD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer.

Acta Pharmacol Sin 2019 Dec 5;40(12):1596-1602. Epub 2019 Jun 5.

Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41401-019-0251-7DOI Listing
December 2019

Antitumor effect of axitinib combined with dopamine and PK-PD modeling in the treatment of human breast cancer xenograft.

Acta Pharmacol Sin 2019 Feb 17;40(2):243-256. Epub 2018 May 17.

Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery System, Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41401-018-0006-x
Publisher Site
http://dx.doi.org/10.1038/s41401-018-0006-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329750PMC
February 2019

Time-dependent pharmacokinetics of dexamethasone and its efficacy in human breast cancer xenograft mice: a semi-mechanism-based pharmacokinetic/pharmacodynamic model.

Acta Pharmacol Sin 2018 Mar 9;39(3):472-481. Epub 2017 Nov 9.

Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2017.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843834PMC
March 2018

Integrated pharmacokinetic/viral dynamic model for daclatasvir/asunaprevir in treatment of patients with genotype 1 chronic hepatitis C.

Acta Pharmacol Sin 2018 Jan 7;39(1):140-153. Epub 2017 Sep 7.

Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/aps.2017.84
Publisher Site
http://dx.doi.org/10.1038/aps.2017.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758672PMC
January 2018

Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer.

Acta Pharmacol Sin 2017 Sep 26;38(9):1282-1296. Epub 2017 Jun 26.

Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2017.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589964PMC
September 2017

Population pharmacokinetic analysis of tacrolimus in Chinese myasthenia gravis patients.

Acta Pharmacol Sin 2017 Aug 29;38(8):1195-1204. Epub 2017 May 29.

Department of Pharmacy, General Hospital of PLA Rocket Force, Beijing 100088, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2016.174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547552PMC
August 2017

[Population pharmacokinetics and its application in new drug research].

Yao Xue Xue Bao 2017 Mar;52(3):371-7

View Article

Download full-text PDF

Source
March 2017

Urea-containing peptide boronic acids as potent proteasome inhibitors.

Eur J Med Chem 2017 Jan 14;125:925-939. Epub 2016 Oct 14.

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmech.2016.10.023DOI Listing
January 2017

Preclinical PK/PD model for combined administration of erlotinib and sunitinib in the treatment of A549 human NSCLC xenograft mice.

Acta Pharmacol Sin 2016 Jul 16;37(7):930-40. Epub 2016 May 16.

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2016.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933764PMC
July 2016

Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen.

Acta Pharmacol Sin 2016 Jun 2;37(6):845-56. Epub 2016 May 2.

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2016.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954770PMC
June 2016

Pharmacokinetic-pharmacodynamic modeling of the antitumor effect of TM208 and EGFR-TKI resistance in human breast cancer xenograft mice.

Acta Pharmacol Sin 2016 Jun 2;37(6):825-33. Epub 2016 May 2.

Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2016.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954772PMC
June 2016

Intratumoral estrogen sulfotransferase induction contributes to the anti-breast cancer effects of the dithiocarbamate derivative TM208.

Acta Pharmacol Sin 2015 Oct 4;36(10):1246-55. Epub 2015 May 4.

Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2015.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814201PMC
October 2015

Model-based meta-analysis of the effects of non-selective and α1-selective GABAA receptor agonists in healthy volunteers.

Eur J Clin Pharmacol 2015 Oct 11;71(10):1209-21. Epub 2015 Aug 11.

The State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00228-015-1918-8DOI Listing
October 2015

[Current applications of dexamethasone for cancer treatment].

Yao Xue Xue Bao 2015 Oct;50(10):1217-24

View Article

Download full-text PDF

Source
October 2015

Breast cancer treatment and sulfotransferase.

Expert Opin Ther Targets 2015 Jun 12;19(6):821-34. Epub 2015 Feb 12.

Institute of Clinical Pharmacology, Peking University First Hospital, Peking University , Beijing , China

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.2015.1014803DOI Listing
June 2015

A population pharmacokinetic study of tacrolimus in healthy Chinese volunteers and liver transplant patients.

Acta Pharmacol Sin 2015 Feb 15;36(2):281-8. Epub 2014 Dec 15.

1] Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China [2] State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2014.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326784PMC
February 2015

Alzheimer's disease progression model based on integrated biomarkers and clinical measures.

Acta Pharmacol Sin 2014 Sep 4;35(9):1111-20. Epub 2014 Aug 4.

1] State Key Laboratory of Natural and Biomimetic Drugs (Peking University), Beijing 100191, China [2] Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2014.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155529PMC
September 2014

Population pharmacokinetic/pharmacodynamic model of clozapine for characterizing the relationship between accumulated exposure and PANSS scores in patients with schizophrenia.

Ther Drug Monit 2014 Jun;36(3):378-86

*Beijing Key Laboratory for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China; †Department of Pharmacy, Guangzhou Brain Hospital, Guangzhou Medical University; ‡Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; §Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University; and ¶Beijing Key Lab of Brain Major Disorders-State Key Lab Incubation Base, Beijing Neuroscience Disciplines, Capital Medical University, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FTD.0000000000000014DOI Listing
June 2014

Inhibition of EGFR autophosphorylation plays an important role in the anti-breast cancer efficacy of the dithiocarbamate derivative TM208.

Acta Pharmacol Sin 2014 Feb 30;35(2):239-47. Epub 2013 Dec 30.

1] State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China [2] Department of Pharmaceutics, School of Pharmaceutical sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/aps2013156
Publisher Site
http://dx.doi.org/10.1038/aps.2013.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651224PMC
February 2014

Pharmacokinetic-pharmacodynamic modeling of the anticancer effect of erlotinib in a human non-small cell lung cancer xenograft mouse model.

Acta Pharmacol Sin 2013 Nov 7;34(11):1427-36. Epub 2013 Oct 7.

Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2013.101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006468PMC
November 2013

Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma.

Acta Pharmacol Sin 2013 Jul 22;34(7):951-9. Epub 2013 Apr 22.

State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2013.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002606PMC
July 2013

Pharmacokinetic/pharmacodynamic studies on exenatide in diabetic rats.

Acta Pharmacol Sin 2012 Nov 4;33(11):1379-86. Epub 2012 Jun 4.

Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2012.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011360PMC
November 2012

Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China.

Acta Pharmacol Sin 2012 Nov 29;33(11):1401-8. Epub 2012 Oct 29.

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/aps.2012.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011351PMC
November 2012

A mechanism-based pharmacokinetic/pharmacodynamic model for CYP3A1/2 induction by dexamethasone in rats.

Acta Pharmacol Sin 2012 Jan;33(1):127-36

Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/aps2011161
Publisher Site
http://dx.doi.org/10.1038/aps.2011.161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010279PMC
January 2012

[Comparison study of model evaluation methods: normalized prediction distribution errors vs. visual predictive check].

Yao Xue Xue Bao 2011 Sep;46(9):1123-31

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
September 2011

[The therapeutic drug monitoring network server of tacrolimus for Chinese renal transplant patients].

Yao Xue Xue Bao 2011 Jul;46(7):828-33

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
July 2011

[Application of Fourier amplitude sensitivity test in Chinese healthy volunteer population pharmacokinetic model of tacrolimus].

Yao Xue Xue Bao 2010 Jul;45(7):883-90

The State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
July 2010

Development of a sensitive high-performance liquid chromatographic method with simple extraction for simultaneous determination of huperzine A and huperzine B in the species containing lycopodium alkaloids.

J AOAC Int 2009 Jul-Aug;92(4):1060-3

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100191, People's Republic of China.

View Article

Download full-text PDF

Source
September 2009

[Population pharmacokinetics research of clozapine in Chinese schizophrenic patients].

Yao Xue Xue Bao 2009 Jul;44(7):785-92

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

View Article

Download full-text PDF

Source
July 2009

[Progress in the study of response surface modeling in investigation of drug-drug interaction in anesthetic drugs].

Yao Xue Xue Bao 2008 Dec;43(12):1171-8

School of Pharmaceutical Science, Pekin University, Beijing 100191, China.

View Article

Download full-text PDF

Source
December 2008

Controlled delivery of recombinant hirudin based on thermo-sensitive Pluronic F127 hydrogel for subcutaneous administration: In vitro and in vivo characterization.

J Control Release 2007 Feb 5;117(3):387-95. Epub 2006 Dec 5.

Department of Pharmaceutics, School of Pharmaceutical Science, Peking University, Beijing 100083, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2006.11.024DOI Listing
February 2007