Thorsten Graef

Thorsten Graef

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Thorsten Graef

Thorsten Graef

Publications by authors named "Thorsten Graef"

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Clinical Experience With Ibrutinib Alone or in Combination With Either Cytarabine or Azacitidine in Patients With Acute Myeloid Leukemia.

Clin Lymphoma Myeloma Leuk 2019 Aug 13;19(8):509-515.e1. Epub 2019 May 13.

City of Hope National Medical Center, Duarte, CA.

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http://dx.doi.org/10.1016/j.clml.2019.05.008DOI Listing
August 2019

Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström's Macroglobulinemia.

N Engl J Med 2018 Jun 1;378(25):2399-2410. Epub 2018 Jun 1.

From the National and Kapodistrian University of Athens School of Medicine, Athens (M.A.D., E.K.); ASST Grande Ospedale Metropolitano Niguarda, Milan (A.T.), and Città della Salute Hospital and University, Turin (L.O.) - both in Italy; Concord Hospital, University of Sydney, Concord, NSW (J.T.), and Peter MacCallum Cancer Centre and St. Vincent's Hospital, Melbourne, VIC (C.T.) - both in Australia; Hospital Universitario de Salamanca, Salamanca, Spain (R.G.-S.); Ottawa Hospital, University of Ottawa, Ottawa (D.M.), and Royal Victoria Hospital at McGill University Health Centre, Montreal (C.S.) - both in Canada; Département d'Hématologie, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie, Paris (V.L.), Centre Hospitalier Universitaire de Nantes, Nantes (B.M.), and Centre Hospitalier Régional Universitaire de Lille, Institute of Hematolog-Tranfusion, Lille (C.H.) - all in France; Memorial Sloan Kettering Cancer Center, New York (M.L.P.); Colorado Blood Cancer Institute, Denver (J.V.M.); Dana-Farber Cancer Institute, Boston (S.P.T.); Pharmacyclics, Sunnyvale, CA (J.L., Z.S., T.G.); and Comprehensive Cancer Center Ulm, Institute of Experimental Cancer Research, Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany (C.B.).

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http://dx.doi.org/10.1056/NEJMoa1802917DOI Listing
June 2018

Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia.

Leuk Lymphoma 2017 08 2;58(8):1880-1886. Epub 2016 Dec 2.

h Service d'Hématologie , Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole , Toulouse , France.

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http://dx.doi.org/10.1080/10428194.2016.1263843DOI Listing
August 2017

Extended follow-up with the Bruton's tyrosine kinase inhibitor ibrutinib in previously treated Waldenström's macroglobulinemia.

Leuk Lymphoma 2017 06 26;58(6):1502-1505. Epub 2016 Oct 26.

b Pharmacyclics LLC, an AbbVie Company , Sunnyvale , CA , USA.

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http://dx.doi.org/10.1080/10428194.2016.1247957DOI Listing
June 2017

Ibrutinib in previously treated Waldenström's macroglobulinemia.

N Engl J Med 2015 Apr;372(15):1430-40

From the Bing Center for Waldenström's Macroglobulinemia, Dana-Farber Cancer Institute (S.P.T., C.K.T., K.M., D.W., G.Y., Y.C., L.X., C.J.P., S.K., I.G., J.J.C., J.P.L., Z.R.H.), Harvard Medical School (S.P.T., G.Y., Y.C., S.R., J.C.A., N.L.H., I.G., J.J.C., J.P.L.), Department of Pathology, Brigham and Women's Hospital (S.R., J.C.A.), Department of Pathology, Massachusetts General Hospital (N.L.H.), and Department of Pathology, Boston University Medical Center (Z.R.H.) - all in Boston; Memorial Sloan Kettering Cancer Center, New York (R.G., K.V.A., M.L.P.); and Stanford University Medical Center, Stanford (G.V., J.L.Z., R.H.A.), and Pharmacyclics, Sunnyvale (Z.S., J.L., M.C., F.C., T.G.) - both in California.

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http://dx.doi.org/10.1056/NEJMoa1501548DOI Listing
April 2015

Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I.

J Immunol 2010 Oct 27;185(7):4233-7. Epub 2010 Aug 27.

Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.4049/jimmunol.1001951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124310PMC
October 2010

Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands.

Proc Natl Acad Sci U S A 2009 Nov 16;106(44):18692-7. Epub 2009 Oct 16.

Department of Structural Biology and Microbiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.0906051106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774017PMC
November 2009

Use of RNA interference to inhibit integrin subunit alphaV-mediated angiogenesis.

Angiogenesis 2005 7;8(4):361-72. Epub 2006 Jan 7.

Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Germany.

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http://dx.doi.org/10.1007/s10456-005-9026-5DOI Listing
March 2009

Escalation therapy with bortezomib, dexamethasone and bendamustine for patients with relapsed or refractory multiple myeloma.

Leuk Lymphoma 2007 Dec;48(12):2345-51

Department of Haematology, Oncology and Clinical Immunology, Heinrich-Heine University, Duesseldorf, Germany.

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http://dx.doi.org/10.1080/10428190701694194DOI Listing
December 2007

Successful treatment of relapsed AML after allogeneic stem cell transplantation with azacitidine.

Leuk Res 2007 Feb 18;31(2):257-9. Epub 2006 Apr 18.

Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine University, Moorenstr. 5, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.leukres.2006.03.003DOI Listing
February 2007

Distinct gene expression pattern of malignant hematopoietic stem and progenitor cells in polycythemia vera.

Ann N Y Acad Sci 2005 Jun;1044:94-108

Klinik für Hämatologie, Onkologie und klinische Immunologie, Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, D-40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1196/annals.1349.013DOI Listing
June 2005