Thorarinn Gudjonsson

Thorarinn Gudjonsson

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Thorarinn Gudjonsson

Thorarinn Gudjonsson

Publications by authors named "Thorarinn Gudjonsson"

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Azithromycin has lung barrier protective effects in a cell model mimicking ventilator-induced lung injury.

ALTEX 2020 May 19. Epub 2020 May 19.

Stem Cell Research Unit, BioMedical Center, School of Health Sciences, University of Iceland, Reykjavík, Iceland.

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http://dx.doi.org/10.14573/altex.2001271DOI Listing
May 2020

Innovative in vitro method to study ventilator induced lung injury.

ALTEX 2019 5;36(4):634-642. Epub 2019 Jun 5.

Stem Cell Research Unit, BioMedical Centre, School of Health Sciences, University of Iceland, Reykjavík, Iceland.

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http://dx.doi.org/10.14573/altex.1901182DOI Listing
April 2020

YKL-40/CHI3L1 facilitates migration and invasion in HER2 overexpressing breast epithelial progenitor cells and generates a niche for capillary-like network formation.

In Vitro Cell Dev Biol Anim 2019 Dec 3;55(10):838-853. Epub 2019 Sep 3.

Stem Cell Research Unit, Biomedical Center, Department of Anatomy, Faculty of Medicine, School of Health Sciences, University of Iceland, Vatnsmyrarvegi 16, 101, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s11626-019-00403-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881255PMC
December 2019

Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D Culture.

J Mammary Gland Biol Neoplasia 2019 06 25;24(2):139-147. Epub 2019 Jan 25.

Stem Cell Research Unit, Biomedical Center, Department of Anatomy, Faculty of Medicine, School of Health Sciences, University of Iceland, Vatnsmyrarvegi 16, 101, Reykjavík, Iceland.

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http://link.springer.com/10.1007/s10911-018-09424-w
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http://dx.doi.org/10.1007/s10911-018-09424-wDOI Listing
June 2019

Cell Internalization in Fluidic Culture Conditions Is Improved When Microparticles Are Specifically Targeted to the Human Epidermal Growth Factor Receptor 2 (HER2).

Pharmaceutics 2019 Apr 11;11(4). Epub 2019 Apr 11.

Unitat de Biologia Cel·lular, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Facultat de Biociències, Universitat Autònoma de Barcelona, Bellaterra, 08193 Barcelona, Spain.

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http://dx.doi.org/10.3390/pharmaceutics11040177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523092PMC
April 2019

MiR-203a is differentially expressed during branching morphogenesis and EMT in breast progenitor cells and is a repressor of peroxidasin.

Mech Dev 2019 02 1;155:34-47. Epub 2018 Dec 1.

Stem Cell Research Unit, Biomedical Center, Department of Anatomy, Faculty of Medicine, School of Health Sciences, University of Iceland, Iceland; Department of Laboratory Hematology, Landspitali - University Hospital, Iceland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254773183009
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http://dx.doi.org/10.1016/j.mod.2018.11.002DOI Listing
February 2019

Metabolic re-wiring of isogenic breast epithelial cell lines following epithelial to mesenchymal transition.

Cancer Lett 2017 06 18;396:117-129. Epub 2017 Mar 18.

Center for Systems Biology, University of Iceland, Reykjavik, Iceland; Biomedical Center, University of Iceland, Reykjavík, Iceland.

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http://dx.doi.org/10.1016/j.canlet.2017.03.019DOI Listing
June 2017

Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cells.

Cell Death Dis 2017 05 11;8(5):e2769. Epub 2017 May 11.

Stem Cell Research Unit, Department of Medical Faculty, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/cddis.2017.177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520702PMC
May 2017

Epithelial Plasticity During Human Breast Morphogenesis and Cancer Progression.

J Mammary Gland Biol Neoplasia 2016 12 4;21(3-4):139-148. Epub 2016 Nov 4.

Stem Cell Research Unit, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavík, Iceland.

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http://dx.doi.org/10.1007/s10911-016-9366-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159441PMC
December 2016

Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in culture.

Lab Invest 2015 Dec 21;95(12):1418-28. Epub 2015 Sep 21.

Stem Cell Research Unit, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

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http://www.nature.com/articles/labinvest2015114
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http://dx.doi.org/10.1038/labinvest.2015.114DOI Listing
December 2015

Curcumin, bisdemethoxycurcumin and dimethoxycurcumin complexed with cyclodextrins have structure specific effect on the paracellular integrity of lung epithelia .

Biochem Biophys Rep 2015 Dec 10;4:405-410. Epub 2015 Nov 10.

Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.bbrep.2015.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669517PMC
December 2015

Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia.

Curr Mol Biol Rep 2015 5;1(4):168-174. Epub 2015 Oct 5.

Stem Cell Research Unit, BioMedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s40610-015-0027-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487766PMC
October 2015

MicroRNA-200c-141 and ∆Np63 are required for breast epithelial differentiation and branching morphogenesis.

Dev Biol 2015 Jul 9;403(2):150-61. Epub 2015 May 9.

Stem Cell Research Unit, Biomedical Center, Department of Anatomy, Faculty of Medicine, School of Health Sciences, University of Iceland, Iceland; Department of Laboratory Hematology, Landspitali-University Hospital, Iceland. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2015.05.007DOI Listing
July 2015

deltaNp63 has a role in maintaining epithelial integrity in airway epithelium.

PLoS One 2014 12;9(2):e88683. Epub 2014 Feb 12.

Stem Cell Research Unit, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland ; Department of Pharmacology & Toxicology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland ; Department of Laboratory Hematology, Landspitali University Hospital, Reykjavik, Iceland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088683PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922990PMC
January 2015

Functional Role of the microRNA-200 Family in Breast Morphogenesis and Neoplasia.

Genes (Basel) 2014 Sep 11;5(3):804-20. Epub 2014 Sep 11.

Stem Cell Research Unit, Department of Medical Faculty, Biomedical Center, University of Iceland, Vatnsmyrarvegi 16, 101 Reykjavík, Iceland.

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http://dx.doi.org/10.3390/genes5030804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198932PMC
September 2014

N-alkylation of highly quaternized chitosan derivatives affects the paracellular permeation enhancement in bronchial epithelia in vitro.

Eur J Pharm Biopharm 2014 Jan 19;86(1):55-63. Epub 2013 Apr 19.

Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Reykjavik, Iceland. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2013.04.002DOI Listing
January 2014

Endothelial-rich microenvironment supports growth and branching morphogenesis of prostate epithelial cells.

Prostate 2013 Jun 31;73(8):884-96. Epub 2012 Dec 31.

Stem Cell Research Unit, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1002/pros.22634DOI Listing
June 2013

Drug delivery characteristics of the progenitor bronchial epithelial cell line VA10.

Pharm Res 2013 Mar 8;30(3):781-91. Epub 2012 Nov 8.

Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Hofsvallagata 53, 107, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s11095-012-0919-xDOI Listing
March 2013

Regioselective fluorescent labeling of N,N,N-trimethyl chitosan via oxime formation.

Carbohydr Polym 2012 Oct 1;90(3):1273-80. Epub 2012 Jul 1.

Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.carbpol.2012.06.070DOI Listing
October 2012

Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary background.

In Vitro Cell Dev Biol Anim 2011 Feb 17;47(2):139-48. Epub 2010 Nov 17.

Stem Cell Research Unit, Biomedical Center, University of Iceland and Department of Laboratory Hematology, Landspitali University Hospital, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s11626-010-9371-6DOI Listing
February 2011

Airway branching morphogenesis in three dimensional culture.

Respir Res 2010 Nov 25;11:162. Epub 2010 Nov 25.

Stem Cell Research Unit, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1186/1465-9921-11-162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002372PMC
November 2010

Endothelial cells stimulate growth of normal and cancerous breast epithelial cells in 3D culture.

BMC Res Notes 2010 Jul 7;3:184. Epub 2010 Jul 7.

Stem cell research unit, Department of anatomy, Faculty of medicine, University of Iceland and Department of laboratory hematology, Landspitali, university hospital, (Vatnsmýrarvegur 16), Reykjavík, (101), Iceland.

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http://dx.doi.org/10.1186/1756-0500-3-184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909928PMC
July 2010

Azithromycin maintains airway epithelial integrity during Pseudomonas aeruginosa infection.

Am J Respir Cell Mol Biol 2010 Jan 16;42(1):62-8. Epub 2009 Apr 16.

Institute of Biology, Biomedical Center, University of Iceland, Landspitali, Eiriksgata 5, Reykjavik, Iceland.

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http://dx.doi.org/10.1165/rcmb.2008-0357OCDOI Listing
January 2010

Evanescent-wave fluorescence microscopy using symmetric planar waveguides.

Opt Express 2009 Mar;17(7):5075-82

Department of Physics, Science Institute, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1364/oe.17.005075DOI Listing
March 2009

Differentiation potential of a basal epithelial cell line established from human bronchial explant.

In Vitro Cell Dev Biol Anim 2007 Sep-Oct;43(8-9):283-9. Epub 2007 Sep 18.

Biology Institute, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s11626-007-9050-4DOI Listing
April 2008

[The application of stem cells for research and treatment of neurological disorders].

Laeknabladid 2008 Feb;94(2):117-22

Taugalaekningadeild Karolinska sjúkrahúsins.

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February 2008

Evidence for a stem cell hierarchy in the adult human breast.

J Cell Biol 2007 Apr;177(1):87-101

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, and Zoophysiological Laboratory, University of Copenhagen, and Department of Pathology, State University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1083/jcb.200611114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064114PMC
April 2007

Establishment of three human breast epithelial cell lines derived from carriers of the 999del5 BRCA2 Icelandic founder mutation.

In Vitro Cell Dev Biol Anim 2005 Nov-Dec;41(10):337-42

Faculty of Medicine, University of Iceland, Molecular and Cell Biology Research Laboratory, Icelandic Cancer Society, Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s11626-005-0005-3DOI Listing
October 2006

Novel effects of azithromycin on tight junction proteins in human airway epithelia.

Antimicrob Agents Chemother 2006 May;50(5):1805-12

Faculty of Medicine, Landspitali University Hospital, Fossvogi E7, 108 Reykjavik, Iceland.

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http://dx.doi.org/10.1128/AAC.50.5.1805-1812.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472195PMC
May 2006

Stem cell biology and the cellular pathways of carcinogenesis.

APMIS 2005 Nov-Dec;113(11-12):922-9

Molecular and Cell Biology Research Laboratory, Icelandic Cancer Society, Reykjavik, Iceland.

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http://dx.doi.org/10.1111/j.1600-0463.2005.apm_371.xDOI Listing
April 2006

Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia.

J Mammary Gland Biol Neoplasia 2005 Jul;10(3):261-72

Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/s10911-005-9586-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798159PMC
July 2005

Maintenance of cell type diversification in the human breast.

J Mammary Gland Biol Neoplasia 2005 Jan;10(1):61-74

Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s10911-005-2541-6DOI Listing
January 2005

Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression.

In Vitro Cell Dev Biol Anim 2003 Jul-Aug;39(7):297-303

Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark.

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http://dx.doi.org/10.1290/1543-706X(2003)039<0297:CGCSTR>2.0.CO;2DOI Listing
July 2004

Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia.

Cell Prolif 2003 Oct;36 Suppl 1:33-44

Structural Cell Biology Unit, Institute of Medical Anatomy, The Panum Institute, Copenhagen, Denmark.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933221PMC
http://dx.doi.org/10.1046/j.1365-2184.36.s.1.4.xDOI Listing
October 2003

Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma.

Am J Pathol 2003 Feb;162(2):391-402

Structural Cell Biology Unit, Department of Medical Anatomy, Section A, the Panum Institute, Copenhagen, Denmark.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851146PMC
http://dx.doi.org/10.1016/S0002-9440(10)63834-5DOI Listing
February 2003