Thor Theander

Thor Theander

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Malaria in Early Pregnancy and the Development of the Placental Vasculature.

J Infect Dis 2019 Sep;220(9):1425-1434

Centre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen.

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http://dx.doi.org/10.1093/infdis/jiy735DOI Listing
September 2019

Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein.

Cells 2019 Aug 28;8(9). Epub 2019 Aug 28.

Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Disease, Copenhagen University Hospital, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.3390/cells8090998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769911PMC
August 2019

Anemia in late pregnancy induces an adaptive response in fetoplacental vascularization.

Placenta 2019 May 26;80:49-58. Epub 2019 Mar 26.

Core Center for Molecular Morphology, Section for Stereology and Microscopy, Centre for Stochastic Geometry and Advanced Bioimaging, Department of Clinical Medicine, C113, level 1, Palle Juul Jensens Boulevard 99, Aarhus University, DK-8200, Aarhus N, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2019.03.009DOI Listing
May 2019

Immunization with Recombinant Plasmodium falciparum Erythrocyte Membrane Protein 1 CIDRα1 Domains Induces Domain Subtype Inhibitory Antibodies.

Infect Immun 2018 11 25;86(11). Epub 2018 Oct 25.

Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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http://dx.doi.org/10.1128/IAI.00435-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204696PMC
November 2018

Virus-like particle display of HER2 induces potent anti-cancer responses.

Oncoimmunology 2018 5;7(3):e1408749. Epub 2018 Jan 5.

Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, and Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/2162402X.2017.1408749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790387PMC
January 2018

Plasmodium falciparum Infection Early in Pregnancy has Profound Consequences for Fetal Growth.

J Infect Dis 2017 12;216(12):1601-1610

Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1093/infdis/jix530DOI Listing
December 2017

Pre-clinical and clinical development of the first placental malaria vaccine.

Expert Rev Vaccines 2017 06 28;16(6):613-624. Epub 2017 Apr 28.

a Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Science , University of Copenhagen , Copenhagen , Denmark.

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http://dx.doi.org/10.1080/14760584.2017.1322512DOI Listing
June 2017

Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display.

Vaccine 2017 06 31;35(30):3726-3732. Epub 2017 May 31.

Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Denmark; Department of Infectious Diseases, Copenhagen University Hospital, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.05.054DOI Listing
June 2017

Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1.

J Infect Dis 2017 06;215(12):1918-1925

UMR 216, Mère et enfant face aux infections tropicales, Institut de Recherche pour le développement, COMUE Sorbonne Paris Cité, Faculté de pharmacie, Laboratoire d'Excellence GR-Ex, DHU Risques et Grossesse, France.

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http://dx.doi.org/10.1093/infdis/jix230DOI Listing
June 2017

The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.

Infect Immun 2017 04 23;85(4). Epub 2017 Mar 23.

Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, University of Copenhagen, and Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark

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http://dx.doi.org/10.1128/IAI.00841-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364309PMC
April 2017

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.

Cell Host Microbe 2017 Mar;21(3):403-414

Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen, 1165 Copenhagen, Denmark; Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), 2100 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374107PMC
March 2017

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites.

Malar J 2017 02 10;16(1):69. Epub 2017 Feb 10.

Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, Centre for Medical Parasitology, University of Copenhagen, CSS Building 22-23, Øster Farimagsgade 5, PO Box 2099, 1014, Copenhagen K, Denmark.

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http://dx.doi.org/10.1186/s12936-017-1714-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301330PMC
February 2017

Comparison of functional assays used in the clinical development of a placental malaria vaccine.

Vaccine 2017 01 21;35(4):610-618. Epub 2016 Dec 21.

Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.12.028DOI Listing
January 2017

Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1.

Sci Rep 2016 10 27;6:35950. Epub 2016 Oct 27.

Centre for Medical Parasitology, Department of Immunology &Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/srep35950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082358PMC
October 2016

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.

EMBO Mol Med 2016 08 1;8(8):839-50. Epub 2016 Aug 1.

Centre for Medical Parasitology, Department of Immunology & Microbiology, University of Copenhagen, Copenhagen, Denmark Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark

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http://dx.doi.org/10.15252/emmm.201606188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967939PMC
August 2016

Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting.

Sens Biosensing Res 2016 Jul;9:23-30

Centre for Medical Parasitology at Department of Immunology and Microbiology, University of Copenhagen, Denmark; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.sbsr.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942562PMC
July 2016

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.

PLoS One 2015 23;10(11):e0143071. Epub 2015 Nov 23.

Centre for Medical Parasitology at the Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143071PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657905PMC
June 2016

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.

Malar J 2016 05 26;15(1):292. Epub 2016 May 26.

Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen and at Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://dx.doi.org/10.1186/s12936-016-1342-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881162PMC
May 2016

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania.

Malar J 2015 Dec 1;14:474. Epub 2015 Dec 1.

Centre for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Science, University of Copenhagen, Østerfarimagsgade 5, Building 22-23, 1356, Copenhagen K, Denmark.

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http://dx.doi.org/10.1186/s12936-015-1007-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666078PMC
December 2015

Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant.

Thromb Haemost 2015 Nov 9;114(5):1038-48. Epub 2015 Jul 9.

Jens E. V. Petersen, Centre for Medical Parasitology, Dept. of International Health, Immunology & Microbiology, University of Copenhagen and Dept. of Infectious Diseases, Rigshospitalet, 1014 Copenhagen, Denmark, Tel.: +45 35327549, Fax: +45 35327851, E-mail:

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http://dx.doi.org/10.1160/TH15-01-0018DOI Listing
November 2015

IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria.

Infect Immun 2015 Aug 26;83(8):3096-103. Epub 2015 May 26.

Centre for Medical Parasitology, Department of International Health, Immunology, and Microbiology, University of Copenhagen, and Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1128/IAI.00271-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496620PMC
August 2015

Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.

PLoS One 2014 21;9(1):e84981. Epub 2014 Jan 21.

Centre for Medical Parasitology at Department of International Health, Immunology, and Microbiology, University of Copenhagen and at Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084981PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897377PMC
October 2014

Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.

PLoS One 2013 9;8(7):e69117. Epub 2013 Jul 9.

Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, Copenhagen University Hospital (Rigshospitalet), University of Copenhagen, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069117PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706608PMC
February 2014

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.

Nucleic Acids Res 2014 Feb 18;42(4):2270-81. Epub 2013 Nov 18.

Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5, Building 22 & 23, PO Box 2099, 1014 Copenhagen K, Denmark, Centre for Medical Parasitology, Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen K, Denmark, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark, Department of Biology, University of Copenhagen, Ole Maaloees Vej 5, DK-2200 Copenhagen N, Denmark, Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark, Institute of Infection and Immunology Research, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, Scotland, UK and Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1093/nar/gkt1174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936766PMC
February 2014

Severe malaria is associated with parasite binding to endothelial protein C receptor.

Nature 2013 Jun 5;498(7455):502-5. Epub 2013 Jun 5.

Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nature12216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870021PMC
June 2013

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.

PLoS One 2012 6;7(9):e43663. Epub 2012 Sep 6.

Centre for Medical Parasitology at the Department of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043663PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435390PMC
May 2013

Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: a longitudinal observational study.

PLoS One 2012 21;7(9):e44773. Epub 2012 Sep 21.

Centre for Medical Parasitology, Institute of International Health, Immunology, and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044773PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448622PMC
March 2013

A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.

J Immunol 2013 Jan 3;190(1):240-9. Epub 2012 Dec 3.

Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 1014, Denmark.

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http://dx.doi.org/10.4049/jimmunol.1202578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539686PMC
January 2013

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.

Authors:
Selidji Todagbe Agnandji Bertrand Lell José Francisco Fernandes Béatrice Peggy Abossolo Barbara Gaelle Nfono Ondo Methogo Anita Lumeka Kabwende Ayola Akim Adegnika Benjamin Mordmüller Saadou Issifou Peter Gottfried Kremsner Jahit Sacarlal Pedro Aide Miguel Lanaspa John J Aponte Sonia Machevo Sozinho Acacio Helder Bulo Betuel Sigauque Eusébio Macete Pedro Alonso Salim Abdulla Nahya Salim Rose Minja Maxmillian Mpina Saumu Ahmed Ali Mohammed Ali Ali Takadir Mtoro Ali Said Hamad Paul Mutani Marcel Tanner Halidou Tinto Umberto D'Alessandro Hermann Sorgho Innocent Valea Biébo Bihoun Issa Guiraud Berenger Kaboré Olivier Sombié Robert Tinga Guiguemdé Jean Bosco Ouédraogo Mary J Hamel Simon Kariuki Martina Oneko Chris Odero Kephas Otieno Norbert Awino Meredith McMorrow Vincent Muturi-Kioi Kayla F Laserson Laurence Slutsker Walter Otieno Lucas Otieno Nekoye Otsyula Stacey Gondi Allan Otieno Victorine Owira Esther Oguk George Odongo Jon Ben Woods Bernhards Ogutu Patricia Njuguna Roma Chilengi Pauline Akoo Christine Kerubo Charity Maingi Trudie Lang Ally Olotu Philip Bejon Kevin Marsh Gabriel Mwambingu Seth Owusu-Agyei Kwaku Poku Asante Kingsley Osei-Kwakye Owusu Boahen David Dosoo Isaac Asante George Adjei Evans Kwara Daniel Chandramohan Brian Greenwood John Lusingu Samwel Gesase Anangisye Malabeja Omari Abdul Coline Mahende Edwin Liheluka Lincoln Malle Martha Lemnge Thor G Theander Chris Drakeley Daniel Ansong Tsiri Agbenyega Samuel Adjei Harry Owusu Boateng Theresa Rettig John Bawa Justice Sylverken David Sambian Anima Sarfo Alex Agyekum Francis Martinson Irving Hoffman Tisungane Mvalo Portia Kamthunzi Rutendo Nkomo Tapiwa Tembo Gerald Tegha Mercy Tsidya Jane Kilembe Chimwemwe Chawinga W Ripley Ballou Joe Cohen Yolanda Guerra Erik Jongert Didier Lapierre Amanda Leach Marc Lievens Opokua Ofori-Anyinam Aurélie Olivier Johan Vekemans Terrell Carter David Kaslow Didier Leboulleux Christian Loucq Afiya Radford Barbara Savarese David Schellenberg Marla Sillman Preeti Vansadia

N Engl J Med 2012 Dec 9;367(24):2284-95. Epub 2012 Nov 9.

Albert Schweitzer Hospital, Lambaréné, Gabon.

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http://dx.doi.org/10.1056/NEJMoa1208394DOI Listing
December 2012

Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes.

Malar J 2012 Dec 21;11:429. Epub 2012 Dec 21.

Centre for Medical Parasitology, Department of International Health, Immunology, and Microbiology, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1475-2875-11-429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544569PMC
December 2012

Factors associated with and causes of perinatal mortality in northeastern Tanzania.

Acta Obstet Gynecol Scand 2012 Sep;91(9):1061-8

Centre for Medical Parasitology, Institute of International Health, Immunology, and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital, Øster Farimagsgade 5, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1600-0412.2012.01478.xDOI Listing
September 2012

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children.

Proc Natl Acad Sci U S A 2012 Jun 22;109(26):E1791-800. Epub 2012 May 22.

Centre for Medical Parasitology, Department of International Health, Immunology, and Microbiology, Faculty of Health Sciences, University of Copenhagen, Rigshospitalet, 1014 Copenhagen K, Denmark.

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http://dx.doi.org/10.1073/pnas.1120455109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387094PMC
June 2012

Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.

Malar J 2012 Apr 25;11:129. Epub 2012 Apr 25.

Centre for Medical Parasitology at Department of International Health, Immunology, and Microbiology, University of Copenhagen and at Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), 1014, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1475-2875-11-129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407477PMC
April 2012

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.

Authors:
Selidji Todagbe Agnandji Bertrand Lell Solange Solmeheim Soulanoudjingar José Francisco Fernandes Béatrice Peggy Abossolo Cornelia Conzelmann Barbara Gaelle Nfono Ondo Methogo Yannick Doucka Arnaud Flamen Benjamin Mordmüller Saadou Issifou Peter Gottfried Kremsner Jahit Sacarlal Pedro Aide Miguel Lanaspa John J Aponte Arlindo Nhamuave Diana Quelhas Quique Bassat Sofia Mandjate Eusébio Macete Pedro Alonso Salim Abdulla Nahya Salim Omar Juma Mwanajaa Shomari Kafuruki Shubis Francisca Machera Ali Said Hamad Rose Minja Ali Mtoro Alma Sykes Saumu Ahmed Alwisa Martin Urassa Ali Mohammed Ali Grace Mwangoka Marcel Tanner Halidou Tinto Umberto D'Alessandro Hermann Sorgho Innocent Valea Marc Christian Tahita William Kaboré Sayouba Ouédraogo Yara Sandrine Robert Tinga Guiguemdé Jean Bosco Ouédraogo Mary J Hamel Simon Kariuki Chris Odero Martina Oneko Kephas Otieno Norbert Awino Jackton Omoto John Williamson Vincent Muturi-Kioi Kayla F Laserson Laurence Slutsker Walter Otieno Lucas Otieno Otsyula Nekoye Stacey Gondi Allan Otieno Bernhards Ogutu Ruth Wasuna Victorine Owira David Jones Agnes Akoth Onyango Patricia Njuguna Roma Chilengi Pauline Akoo Christine Kerubo Jesse Gitaka Charity Maingi Trudie Lang Ally Olotu Benjamin Tsofa Philip Bejon Norbert Peshu Kevin Marsh Seth Owusu-Agyei Kwaku Poku Asante Kingsley Osei-Kwakye Owusu Boahen Samuel Ayamba Kingsley Kayan Ruth Owusu-Ofori David Dosoo Isaac Asante George Adjei George Adjei Daniel Chandramohan Brian Greenwood John Lusingu Samwel Gesase Anangisye Malabeja Omari Abdul Hassan Kilavo Coline Mahende Edwin Liheluka Martha Lemnge Thor Theander Chris Drakeley Daniel Ansong Tsiri Agbenyega Samuel Adjei Harry Owusu Boateng Theresa Rettig John Bawa Justice Sylverken David Sambian Alex Agyekum Larko Owusu Francis Martinson Irving Hoffman Tisungane Mvalo Portia Kamthunzi Ruthendo Nkomo Albans Msika Allan Jumbe Nelecy Chome Dalitso Nyakuipa Joseph Chintedza W Ripley Ballou Myriam Bruls Joe Cohen Yolanda Guerra Erik Jongert Didier Lapierre Amanda Leach Marc Lievens Opokua Ofori-Anyinam Johan Vekemans Terrell Carter Didier Leboulleux Christian Loucq Afiya Radford Barbara Savarese David Schellenberg Marla Sillman Preeti Vansadia

N Engl J Med 2011 11 18;365(20):1863-75. Epub 2011 Oct 18.

Albert Schweitzer Hospital, Lambarene, Gabon.

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http://dx.doi.org/10.1056/NEJMoa1102287DOI Listing
November 2011

Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women.

J Infect Dis 2011 Jun;203(11):1679-85

Centre for Medical Parasitology, Department of International Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/infdis/jir168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096795PMC
June 2011

The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains.

J Biol Chem 2011 May 11;286(18):15908-17. Epub 2011 Mar 11.

Department of International Health, Immunology, University of Copenhagen and the Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen K, Denmark.

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http://dx.doi.org/10.1074/jbc.M110.191510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091200PMC
May 2011

Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection.

J Pharm Biomed Anal 2011 Jan 17;54(1):168-72. Epub 2010 Aug 17.

Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen, Denmark.

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http://linkinghub.elsevier.com/retrieve/pii/S073170851000469
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http://dx.doi.org/10.1016/j.jpba.2010.08.009DOI Listing
January 2011

Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1.

PLoS Pathog 2010 Sep 2;6(9):e1001083. Epub 2010 Sep 2.

Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, Faculty of Health Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://dx.doi.org/10.1371/journal.ppat.1001083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932717PMC
September 2010

Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.

PLoS Comput Biol 2010 Sep 16;6(9). Epub 2010 Sep 16.

Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark.

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http://dx.doi.org/10.1371/journal.pcbi.1000933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940729PMC
September 2010

Clustering of malaria treatment failure (TF) in Daraweesh: hints for host genetic susceptibility to TF with emphasis on immune-modulating SNPs.

Infect Genet Evol 2010 May 7;10(4):481-6. Epub 2010 Mar 7.

Department of Medical Biochemistry, Faculty of Medicine and Medical Sciences, Arabian Gulf University, PO Box 26671, Manama, Bahrain.

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http://linkinghub.elsevier.com/retrieve/pii/S156713481000047
Publisher Site
http://dx.doi.org/10.1016/j.meegid.2010.02.013DOI Listing
May 2010

The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs.

Malar J 2010 Apr 19;9:100. Epub 2010 Apr 19.

Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, Faculty of Health Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), CSS Øster Farimagsgade 5, Building 22 & 23, Postbox 2099, 1014 Copenhagen K, Denmark.

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http://dx.doi.org/10.1186/1475-2875-9-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868858PMC
April 2010

Age-dependent association between IgG2 and IgG3 subclasses to Pf332-C231 antigen and protection from malaria, and induction of protective antibodies by sub-patent malaria infections, in Daraweesh.

Vaccine 2010 Feb 28;28(7):1732-9. Epub 2009 Dec 28.

Department of Medical Biochemistry, Faculty of Medicine and Medical Sciences, Arabian Gulf University AGU, PO Box 26671, Manama, Kingdom of Bahrain.

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http://dx.doi.org/10.1016/j.vaccine.2009.12.018DOI Listing
February 2010

Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies.

Malar J 2010 Jan 11;9:11. Epub 2010 Jan 11.

Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817698PMC
January 2010

The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer.

Parasitol Int 2009 Dec 16;58(4):478-80. Epub 2009 Jul 16.

Department of International Health, Immunology, and Microbiology, University of Copenhagen, Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.parint.2009.07.004DOI Listing
December 2009

Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites.

Int J Parasitol 2009 Sep 24;39(11):1195-204. Epub 2009 Mar 24.

Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, University of Copenhagen ), CSS, Øster Farimagsgade 5 A, DK-1014 Copenhagen K, Denmark.

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http://dx.doi.org/10.1016/j.ijpara.2009.02.022DOI Listing
September 2009

Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains.

J Immunol 2009 Sep 12;183(5):3356-63. Epub 2009 Aug 12.

Centre for Medical Parasitology at Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.4049/jimmunol.0901331DOI Listing
September 2009

Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA.

Infect Immun 2009 Jun 23;77(6):2482-7. Epub 2009 Mar 23.

Department of International Health, Immunology, and Microbiology, University of Copenhagen, Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.

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http://iai.asm.org/content/early/2009/03/23/IAI.00159-09.ful
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687338PMC
June 2009

Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines.

Int J Parasitol 2009 May 30;39(6):655-64. Epub 2008 Dec 30.

Centre for Medical Parasitology at Department of International Health, Immunology, and Microbiology, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.ijpara.2008.11.014DOI Listing
May 2009

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes.

J Infect Dis 2008 Oct;198(7):1071-4

Institute of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1086/591502DOI Listing
October 2008

CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression.

Malar J 2008 Oct 9;7:204. Epub 2008 Oct 9.

Centre for Medical Parasitology at the Institute of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1475-2875-7-204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572619PMC
October 2008

Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania.

Infect Immun 2008 Jun 4;76(6):2706-14. Epub 2008 Feb 4.

Centre for Medical Parasitology at Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), and Institute of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1128/IAI.01401-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423063PMC
June 2008

A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes.

Malar J 2008 Jun 5;7:101. Epub 2008 Jun 5.

Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, Faculty of Health Sciences, University of Copenhagen, Copenhagen K, Denmark.

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http://dx.doi.org/10.1186/1475-2875-7-101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453135PMC
June 2008

Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA.

Malar J 2008 Jun 6;7:104. Epub 2008 Jun 6.

Centre for Medical Parasitology, Institute of International Health Immunology and Microbiology, University of Copenhagen, Department of Clinical Microbiology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://malariajournal.biomedcentral.com/articles/10.1186/147
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430714PMC
June 2008

A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma.

Malar J 2008 Jun 12;7:108. Epub 2008 Jun 12.

Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1475-2875-7-108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435541PMC
June 2008

Reduced risk of uncomplicated malaria episodes in children with alpha+-thalassemia in northeastern Tanzania.

Am J Trop Med Hyg 2008 May;78(5):714-20

Centre for Medical Parasitology, Institute for International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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May 2008

Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.

PLoS One 2008 Mar 26;3(3):e1855. Epub 2008 Mar 26.

Institut de Recherche pour le Développement, UR010 at Université Paris Descartes, Mother and Child Health in the Tropics, Faculté de Pharmacie, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001855PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267001PMC
March 2008

Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum.

Malar J 2007 Nov 16;6:153. Epub 2007 Nov 16.

Centre for Medical Parasitology, Institute of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1475-2875-6-153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206045PMC
November 2007

Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites.

Malar J 2007 Jun 12;6:78. Epub 2007 Jun 12.

Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1475-2875-6-78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904452PMC
June 2007