Publications by authors named "Thomas W Frazier"

99Publications

Affective Processing Biases in Relation to Past, Current, and Future Depression in Children and Adolescents.

J Affect Disord 2020 08 1;273:146-156. Epub 2020 May 1.

Department of Psychiatry, Division of Child and Adolescent Psychiatry, Case Western Reserve University, Cleveland, OH; and Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA; and Division of Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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August 2020

Exploring Social Subtypes in Autism Spectrum Disorder: A Preliminary Study.

Autism Res 2020 08 18;13(8):1335-1342. Epub 2020 Mar 18.

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.

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August 2020

Copy Number Variation and Clinical Outcomes in Patients With Germline PTEN Mutations.

JAMA Netw Open 2020 01 3;3(1):e1920415. Epub 2020 Jan 3.

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.

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January 2020

Developing more clinically useful biomarkers in autism spectrum disorder.

Dev Med Child Neurol 2020 02;62(2):153

Department of Health Sciences, Northeastern University, Boston, MA, USA.

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February 2020

Is the Finding Too Good to Be True? Moving from "More Is Better" to Thinking in Terms of Simple Predictions and Credibility.

J Clin Child Adolesc Psychol 2019 Nov-Dec;48(6):811-824. Epub 2019 Oct 16.

Division of Health Research, Faculty of Health and Medicine, Lancaster University.

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May 2020

Distinct Alterations in Tricarboxylic Acid Cycle Metabolites Associate with Cancer and Autism Phenotypes in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome.

Am J Hum Genet 2019 10 26;105(4):813-821. Epub 2019 Sep 26.

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Germline High Risk Cancer Focus Group, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address:

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October 2019

A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder: An RCT.

Pediatrics 2019 09 6;144(3). Epub 2019 Aug 6.

Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, California.

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September 2019

Autism Spectrum Disorder Associated with Germline Heterozygous Mutations.

Authors:
Thomas W Frazier

Cold Spring Harb Perspect Med 2019 10 1;9(10). Epub 2019 Oct 1.

Autism Speaks, New York, New York 10016, USA.

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October 2019

A proton MR spectroscopy study of the thalamus in twins with autism spectrum disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2018 Feb 21;81:153-160. Epub 2017 Sep 21.

Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA.

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February 2018

Erratum to: Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study.

Int J Bipolar Disord 2017 Sep 18;5(1):33. Epub 2017 Sep 18.

UT Center of Excellence on Mood Disorder, Department of Psychiatry and Behavioral Sciences, The University of Texas Science Center at Houston, Houston, TX, USA.

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September 2017

Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study.

Int J Bipolar Disord 2017 Sep 1;5(1):32. Epub 2017 Sep 1.

UT Center of Excellence on Mood Disorder, Department of Psychiatry and Behavioral Sciences, The University of Texas Science Center at Houston, Houston, TX, USA.

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September 2017

A Longitudinal Pilot Study of Behavioral Abnormalities in Children with Autism.

J Psychiatry Psychiatr Disord 2017 Jul 12;1(4):215-223. Epub 2017 Jul 12.

Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA, 94305, USA.

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July 2017

Parenting Stress Among Caregivers of Children With Bipolar Spectrum Disorders.

J Clin Child Adolesc Psychol 2018 26;47(sup1):S306-S320. Epub 2017 Feb 26.

e Department of Psychiatry and Behavioral Health , The Ohio State University Wexner Medical Center.

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September 2019

Sensing Technologies for Autism Spectrum Disorder Screening and Intervention.

Sensors (Basel) 2016 Dec 27;17(1). Epub 2016 Dec 27.

Al Jalila Children's Specialty Hospital, Dubai, United Arab Emirates.

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December 2016

Disease Burden and Symptom Structure of Autism in Neurofibromatosis Type 1: A Study of the International NF1-ASD Consortium Team (INFACT).

JAMA Psychiatry 2016 Dec;73(12):1276-1284

Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri12Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri.

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December 2016

Equivalence of symptom dimensions in females and males with autism.

Autism 2017 08 7;21(6):749-759. Epub 2016 Aug 7.

2 Stanford University, USA.

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August 2017

Erratum to: Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits.

Mol Autism 2016 3;7:14. Epub 2016 Feb 3.

Genomic Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Mailstop NE-50, Cleveland, OH 44195 USA ; Lerner Research Institute, Cleveland Clinic, Cleveland, OH USA ; HHMI Graduate Program, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH USA ; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH USA ; Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, Cleveland, OH USA ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH USA ; CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH USA.

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February 2016

Perceived barriers to medication adherence in pediatric and adolescent solid organ transplantation.

Pediatr Transplant 2016 Mar 16;20(2):307-15. Epub 2015 Dec 16.

St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, MO, USA.

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March 2016

Development and psychometric evaluation of a psychosocial quality-of-life questionnaire for individuals with autism and related developmental disorders.

Autism 2016 10 10;20(7):832-44. Epub 2015 Dec 10.

Cleveland Clinic Children's Hospital Center for Autism, USA Cleveland Clinic Children's Hospital Center for Pediatric Behavioral Health, USA

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October 2016

Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits.

Mol Autism 2015 17;6:63. Epub 2015 Nov 17.

Genomic Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Mailstop NE-50, Cleveland, OH 44195 USA ; Lerner Research Institute, Cleveland Clinic, Cleveland, OH USA ; HHMI Graduate Program, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH USA ; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH USA ; Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, Cleveland, OH USA ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH USA ; CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH USA.

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November 2015

Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families.

Mol Autism 2015 27;6:58. Epub 2015 Oct 27.

Genomic Medicine Institute, Taussig Cancer Institute, and Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195 USA.

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October 2015

Affective Processing in Pediatric Bipolar Disorder and Offspring of Bipolar Parents.

J Child Adolesc Psychopharmacol 2015 Nov 15;25(9):684-90. Epub 2015 Oct 15.

1 Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston , Houston, Texas.

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November 2015

Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder.

Neurotherapeutics 2015 Jul;12(3):609-19

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.

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July 2015

Pivotal Response Treatment Parent Training for Autism: Findings from a 3-Month Follow-Up Evaluation.

J Autism Dev Disord 2015 Sep;45(9):2889-98

Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA, 94305, USA,

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September 2015

A randomized controlled trial of Pivotal Response Treatment Group for parents of children with autism.

J Child Psychol Psychiatry 2015 Aug 27;56(8):884-92. Epub 2014 Oct 27.

Seattle Children's Hospital/Seattle Children's Research Institute, Seattle, WA, USA.

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August 2015

Chronic pain in children and adolescents: 24-42 month outcomes of an inpatient/day hospital interdisciplinary pain rehabilitation program.

J Pediatr Rehabil Med 2014 ;7(3):197-206

Pediatric Pain Rehabilitation Program, Cleveland Clinic, Cleveland, OH, USA Center for Pediatric Behavioral Health, Cleveland Clinic, Cleveland, OH, USA.

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May 2015

Antidepressants for cognitive impairment in schizophrenia--a systematic review and meta-analysis.

Schizophr Res 2014 Nov 18;159(2-3):385-94. Epub 2014 Sep 18.

The Zucker Hillside Hospital, Psychiatry, North Shore-Long Island Jewish Health System, Glen Oaks, NY, USA; Hofstra North Shore LIJ School of Medicine, Hempstead, NY, USA; The Feinstein Institute for Medical Research, Manhasset, NY, USA; Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address:

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November 2014

Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes.

Brain Behav 2014 May 18;4(3):418-30. Epub 2014 Mar 18.

Department of Psychiatry and Behavioral Sciences, UT Center of Excellence on Mood Disorders, University of Texas Medical School at Houston Houston, Texas.

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May 2014

Dr. Frazier et al. reply.

J Am Acad Child Adolesc Psychiatry 2014 Jun;53(6):700-1

Stanford University, Stanford, CA.

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June 2014

A twin study of heritable and shared environmental contributions to autism.

J Autism Dev Disord 2014 Aug;44(8):2013-25

Center for Autism, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA,

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August 2014

Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.

Hum Mol Genet 2014 Jun 26;23(12):3212-27. Epub 2014 Jan 26.

Howard Hughes Medical Institute Molecular Medicine Program, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Genomic Medicine Institute, Lerner Research Institute, Taussig Cancer Institute, Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, Cleveland, OH 44195, USA, Department of Genetics and Genome Sciences, CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA

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June 2014

A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism.

Prog Neuropsychopharmacol Biol Psychiatry 2014 Jan 25;48:124-8. Epub 2013 Sep 25.

Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford, United States.

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January 2014

Biochemical screening and PTEN mutation analysis in individuals with autism spectrum disorders and macrocephaly.

Eur J Hum Genet 2014 Feb 22;22(2):273-6. Epub 2013 May 22.

1] Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA [2] Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA [3] Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA [4] CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

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February 2014

A two-year longitudinal pilot MRI study of the brainstem in autism.

Behav Brain Res 2013 Aug 22;251:163-7. Epub 2013 Apr 22.

Child Neuroscience Laboratory, Child Study Center, Yale School of Medicine, 230 South Frontage Road, New Haven, CT 06519, USA.

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August 2013

Cognitive characteristics of PTEN hamartoma tumor syndromes.

Genet Med 2013 Jul 7;15(7):548-53. Epub 2013 Mar 7.

Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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July 2013

Age differences in the phenomenology of pediatric bipolar disorder.

J Affect Disord 2013 May 6;147(1-3):295-303. Epub 2012 Dec 6.

Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, OH, United States.

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May 2013

Parents' perceptions of benefit of children's mental health treatment and continued use of services.

Psychiatr Serv 2012 Aug;63(8):793-801

Department of Pediatrics and the Center for Health Policy, Stanford University, 117 Encina Commons, MC 6019, Stanford, CA 94305, USA.

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August 2012

In defense of lumping (and splitting).

J Am Acad Child Adolesc Psychiatry 2012 Apr;51(4):441-2; author reply 442-3

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April 2012

A meta-analysis of adherence to antiretroviral therapy and virologic responses in HIV-infected children, adolescents, and young adults.

AIDS Behav 2013 Jan;17(1):41-60

Services Research Branch, Division of Epidemiology, Services and Prevention Research, National Institute on Drug Abuse, 6001 Executive Blvd, Bethesda, MD 20892, USA.

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January 2013

A two-year longitudinal MRI study of the corpus callosum in autism.

J Autism Dev Disord 2012 Nov;42(11):2312-22

Center for Autism (CRS10) and Pediatric Behavioral Health, Cleveland Clinic, 2801 Martin Luther King Jr. Drive, Cleveland, OH 44104, USA.

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November 2012

A randomized controlled pilot trial of oral N-acetylcysteine in children with autism.

Biol Psychiatry 2012 Jun 18;71(11):956-61. Epub 2012 Feb 18.

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California 94305, USA.

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June 2012

Validation of proposed DSM-5 criteria for autism spectrum disorder.

J Am Acad Child Adolesc Psychiatry 2012 Jan 21;51(1):28-40.e3. Epub 2011 Nov 21.

Center for Pediatric Behavioral Health and Center for Autism, Cleveland Clinic, OH, USA.

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January 2012

Prevalence and correlates of psychotropic medication use in adolescents with an autism spectrum disorder with and without caregiver-reported attention-deficit/hyperactivity disorder.

J Child Adolesc Psychopharmacol 2011 Dec 13;21(6):571-9. Epub 2011 Dec 13.

Center for Autism and Center for Pediatric Behavioral Health, The Cleveland Clinic, Cleveland, Ohio 44195, USA.

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December 2011

Pediatric bipolar spectrum disorder and ADHD: comparison and comorbidity in the LAMS clinical sample.

Bipolar Disord 2011 Aug-Sep;13(5-6):509-21

Division of Child and Adolescent Psychiatry, Department of Psychiatry, Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA.

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February 2012

Portability of a screener for pediatric bipolar disorder to a diverse setting.

Psychol Assess 2012 Jun 26;24(2):341-51. Epub 2011 Sep 26.

Department of Psychology, University of North Carolina at Chapel Hill, NC 27599, USA.

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June 2012

An open-label study of aripiprazole in children with a bipolar disorder.

J Child Adolesc Psychopharmacol 2011 Aug 8;21(4):345-51. Epub 2011 Aug 8.

Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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August 2011

Relationship of persistent manic symptoms to the diagnosis of pediatric bipolar spectrum disorders.

J Clin Psychiatry 2011 Jun 22;72(6):846-53. Epub 2011 Mar 22.

Center for Pediatric Behavioral Health and Center for Autism, Cleveland Clinic, 2801 Martin Luther King Jr Drive, Cleveland, OH 44104, USA.

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June 2011

Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model.

Eur J Hum Genet 2011 Jul 23;19(7):763-8. Epub 2011 Feb 23.

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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July 2011

Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model.

Eur J Hum Genet 2011 Jul 23;19(7):763-8. Epub 2011 Feb 23.

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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July 2011

Bipolar and ADHD Comorbidity: Both Artifact and Outgrowth of Shared Mechanisms.

Clin Psychol (New York) 2010 Dec;17(4):350-359

University of North Carolina at Chapel Hill.

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December 2010

Longitudinal Assessment of Manic Symptoms (LAMS) study: background, design, and initial screening results.

J Clin Psychiatry 2010 Nov 5;71(11):1511-7. Epub 2010 Oct 5.

Department of Pediatrics and Stanford Health Policy, Stanford University School of Medicine, 117 Encina Commons, Stanford, CA 94305-6019, USA.

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November 2010

A meta-analysis of the corpus callosum in autism.

Biol Psychiatry 2009 Nov 12;66(10):935-41. Epub 2009 Sep 12.

Center for Autism and Center for Pediatric Behavioral Health, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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November 2009